Providencia Species – Involvement in Pathology and Multidrug Resistance in a Romanian County Hospital

2021 ◽  
Vol 14 (63) (1) ◽  
pp. 43-50
Author(s):  
Mihaela Elena Idomir
Keyword(s):  
Internal Medicine ◽  
Multidrug Resistance ◽  
Antimicrobial Resistance ◽  
General Surgery ◽  
County Hospital ◽  
Internal Medicine Ward ◽  
Emergency Hospital ◽  
Hospital Wards ◽  
Very High

The aim of the study was to evaluate the distribution on hospital wards, the spectrum of infections and the pattern of antimicrobial resistance of Providencia strains identified between 01.01.2018-31.12.2020 in the samples of the patients hospitalized in the Clinical County Emergency Hospital of Brasov. 380 strains of Providencia species were identified in the medical and surgical wards, especially in ICU (76.84%), Internal medicine ward (5.79%) and General surgery (3.95%). More frequently, Providencia spp. were isolated from tracheobronchial secretions (35.79%), pus (22.89%) and urine (19.74%). The levels of antimicrobial resistance of Providencia strains were very high for all the tested antimicrobials.

scholarly journals Elevated Incidences of Antimicrobial Resistance and Multidrug Resistance in the Maumee River (Ohio, USA), a Major Tributary of Lake Erie

2021 ◽  
Vol 9 (5) ◽  
pp. 911
Author(s):  
Maitreyee Mukherjee ◽  
Leah Marie ◽  
Cheyenne Liles ◽  
Nadia Mustafa ◽  
George Bullerjahn ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Antimicrobial Resistance ◽  
High Resistance ◽  
Lake Erie ◽  
Control Measures ◽  
Industrial Water ◽  
Western Basin ◽  
E Coli ◽  
Major Tributary ◽  
Very High

Maumee River, the major tributary in the western basin of Lake Erie, serves as one of major sources of freshwater in the area, supplying potable, recreational, and industrial water. In this study we collected water samples from four sites in the Maumee River Bay between 2016–2017 and E. coli was isolated, enumerated, and analyzed for antimicrobial resistance (AMR) and multidrug resistance (MDR). Strikingly, 95% of the total isolates were found to be resistant to at least one antibiotic. A very high resistance to the drugs cephalothin (95.3%), ampicillin (38.3%), tetracycline (8.8%), gentamicin (8.2%), ciprofloxacin (4.2%), cefoperazone (4%), and sulfamethoxazole (1.5%) was observed within isolates from all four sampling sites. Percentages of AMR and MDR was consistently very high in the summer and fall months, whereas it was observed to be lowest in the winter. A remarkably high number of the isolates were detected to be MDR—95% resistant to ≥1 antibiotic, 43% resistant to ≥2 antibiotics, 15% resistant to ≥3 antibiotics, 4.9% resistant to ≥4 antibiotic and 1.2% resistant to ≥5 antibiotics. This data will serve in better understanding the environmental occurrence and dissemination of AMR/MDR in the area and assist in improving and establishing control measures.

Antimicrobial resistance and ability to form biofilm of coagulase-negative staphylococci isolated from touch surfaces in Polish hospital wards

2018 ◽  
Vol 2018 (2) ◽  
pp. 73-78
Author(s):  
Małgorzata Bulanda ◽  
Edyta Synowiec ◽  
Agnieszka Chmielarczyk ◽  
Dorota Romaniszyn ◽  
Anna Różańska
Keyword(s):  
Antimicrobial Resistance ◽  
Coagulase Negative Staphylococci ◽  
Hospital Wards

Use of Synthetic Protetic Materials in Surgical Abdominal Defects. Analysis of the Advantages and Lack of the Liechtenstein Method

2018 ◽  
Vol 69 (7) ◽  
pp. 1740-1743
Author(s):  
Vlad Dumitru Baleanu ◽  
Denis Vlad Constantin ◽  
Anca Pascal ◽  
Dragos Ovidiu Alexandru ◽  
Simona Bobic ◽  
...  
Keyword(s):  
Relative Risk ◽  
Recurrence Rate ◽  
General Surgery ◽  
Prosthetic Material ◽  
Emergency Hospital ◽  
Rural And Urban ◽  
Abdominal Interventions ◽  
Defects Analysis ◽  
Surgery Department

Liechtenstein procedure represents the most frequent technique used for surgical abdominal interventions. Although, it is a modern and inovative procedure, it still has a relative risk for complications. A number of 93 subjects were included in our research. We develop our study in General Surgery Department of County Emergency Hospital of Craiova, Romania between 1st July 2017-31th March 2018. From the total of 93 patients, 88% were men. Most of subjects had ages between 70 and 79 years old, were operated by Liechtenstein technique and they were coming from quite equal percent from rural and urban areas.The incidence for complications(seroma, hematoma, infection, abscess) was generally lower for the patients diagnosticated with Liechtenstein procedure comparing with the subjects operated by other technique. Liechtenstein procedureis recommended especially for its simplicity and efficiency, reproducibility and safety. It is very important to choose the perfect synthetic prosthetic material to have a good evolution of the disorder and a small recurrence rate.

Recent Review on Subclass B1 Metallo-β-lactamases Inhibitors: Sword for Antimicrobial Resistance

2019 ◽  
Vol 20 (7) ◽  
pp. 756-762 ◽  
Author(s):  
Aditi Kaushik ◽  
Manish Kaushik ◽  
Viney Lather ◽  
J.S. Dua
Keyword(s):  
Antibiotic Resistance ◽  
Multidrug Resistance ◽  
Antimicrobial Resistance ◽  
Global Health ◽  
Human Health ◽  
Microbial Pathogens ◽  
Present Review ◽  
Drug Molecules ◽  
Global Threat ◽  
Powerful Strategy

An emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations, posing a global threat to human health. The production of the metallo-β-lactamase enzyme is the most powerful strategy of bacteria to produce resistance. An efficient way to combat this global health threat is the development of broad/non-specific type of metallo-β-lactamase inhibitors, which can inhibit the different isoforms of the enzyme. Till date, there are no clinically active drugs against metallo- β-lactamase. The lack of efficient drug molecules against MBLs carrying bacteria requires continuous research efforts to overcome the problem of multidrug-resistance bacteria. The present review will discuss the clinically potent molecules against different variants of B1 metallo-β-lactamase.

scholarly journals Commensal Escherichia coli Antimicrobial Resistance and Multidrug-Resistance Dynamics during Broiler Growing Period: Commercial vs. Improved Farm Conditions

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 1005
Author(s):  
Laura Montoro-Dasi ◽  
Arantxa Villagra ◽  
Sandra Sevilla-Navarro ◽  
Maria Teresa Pérez-Gracia ◽  
Santiago Vega ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Multidrug Resistance ◽  
Antimicrobial Resistance ◽  
Antimicrobial Agents ◽  
Horizontal Resistance ◽  
Growing Period ◽  
Broiler Production ◽  
Field Level ◽  
Poultry Houses ◽  
Growing Conditions

New measures applied to reduce antimicrobial resistances (AMR) at field level in broiler production are focused on improving animals’ welfare and resilience. However, it is necessary to have better knowledge of AMR epidemiology. Thus, the aim of this study was to evaluate AMR and multidrug resistance (MDR) dynamics during the rearing of broilers under commercial (33 kg/m2 density and max. 20 ppm ammonia) and improved (17 kg/m2 density and max. 10 ppm ammonia) farm conditions. Day-old chicks were housed in two poultry houses (commercial vs. improved), and no antimicrobial agents were administered at any point. Animals were sampled at arrival day, mid-period and at slaughter day. High AMR rates were observed throughout rearing. No statistical differences were observed between groups. Moreover, both groups presented high MDR at slaughter day. These results could be explained by vertical or horizontal resistance acquisition. In conclusion, AMR and MDR are present throughout rearing. Moreover, although a lower level of MDR was observed at mid-period in animals reared under less intensive conditions, no differences were found at the end. In order to reduce the presence of AMR bacteria in poultry, further studies are needed to better understand AMR acquisition and prevalence in differing broiler growing conditions.

scholarly journals Antimicrobial resistance profile and multidrug resistance patterns of Streptococcus pneumoniae isolates from patients suspected of pneumococcal infections in Ethiopia

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Bekele Sharew ◽  
Feleke Moges ◽  
Gizachew Yismaw ◽  
Wondwossen Abebe ◽  
Surafal Fentaw ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Streptococcus Pneumoniae ◽  
Antimicrobial Resistance ◽  
Addis Ababa ◽  
Pneumococcal Infection ◽  
Test Method ◽  
Resistance Testing ◽  
Global Public Health ◽  
Pneumococcal Infections ◽  
Resistance Patterns

Abstract Background Antimicrobial-resistant strains of Streptococcus pneumoniae have become one of the greatest challenges to global public health today and inappropriate use of antibiotics and high level of antibiotic use is probably the main factor driving the emergence of resistance worldwide. The aim of this study is, therefore, to assess the antimicrobial resistance profiles and multidrug resistance patterns of S. pneumoniae isolates from patients suspected of pneumococcal infections in Ethiopia. Methods A hospital-based prospective study was conducted from January 2018 to December 2019 at Addis Ababa city and Amhara National Region State Referral Hospitals. Antimicrobial resistance tests were performed from isolates of S. pneumoniae that were collected from pediatric and adult patients. Samples (cerebrospinal fluid, blood, sputum, eye discharge, ear discharge, and pleural and peritoneal fluids) from all collection sites were initially cultured on 5% sheep blood agar plates and incubated overnight at 37 °C in a 5% CO2 atmosphere. Streptococcus pneumoniae was identified and confirmed by typical colony morphology, alpha-hemolysis, Gram staining, optochin susceptibility, and bile solubility test. Drug resistance testing was performed using the E-test method according to recommendations of the Clinical and Laboratory Standards Institute. Results Of the 57 isolates, 17.5% were fully resistant to penicillin. The corresponding value for both cefotaxime and ceftriaxone was 1.8%. Resistance rates to erythromycin, clindamycin, tetracycline, chloramphenicol and trimethoprim-sulfamethoxazole were 59.6%, 17.5%, 38.6%, 17.5 and 24.6%, respectively. Multidrug resistance (MDR) was seen in 33.3% isolates. The most common pattern was co-resistance to penicillin, erythromycin, clindamycin, and tetracycline. Conclusions Most S. pneumoniae isolates were susceptible to ceftriaxone and cefotaxime. Penicillin has been used as a drug of choice for treating S. pneumoniae infection. However, antimicrobial resistance including multidrug resistance was observed to several commonly used antibiotics including penicillin. Hence, it is important to periodically monitor the antimicrobial resistance patterns to select empirical treatments for better management of pneumococcal infection.

scholarly journals Screening for atrial fibrillation during automated blood pressure measurement among patients admitted to internal medicine ward

2021 ◽  
Author(s):  
Giacomo Pucci ◽  
Edoardo Santoni ◽  
Valeria Bisogni ◽  
Camilla Calandri ◽  
Alberto Cerasari ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Atrial Fibrillation ◽  
Blood Pressure ◽  
Adult Population ◽  
Blood Pressure Measurement ◽  
University Hospital ◽  
Daily Routine ◽  
Internal Medicine Ward ◽  
Clinical Conditions ◽  
Electrocardiogram Ecg

AbstractAtrial fibrillation (AF), the commonest sustained cardiac arrhythmia affecting the adult population, is often casually discovered among hospitalized people. AF onset is indeed triggered by several clinical conditions such as acute inflammatory states, infections, and electrolyte disturbance, frequently occurring during the hospitalization. We aimed to evaluate whether systematic AF screening, performed through an automated oscillometric blood pressure (BP) device (Microlife WatchBP Office AFIB, Microlife AG, Switzerland), is effective for detecting AF episodes in subjects admitted to an Internal Medicine ward. 163 patients consecutively hospitalized at the Unit of Internal Medicine of the “Santa Maria” Terni University Hospital between November 2019 and January 2020 (mean age ± standard deviation: 77 ± 14 years, men proportion: 40%) were examined. Simultaneously with BP measurement and AF screening, a standard 12-lead electrocardiogram (ECG) was performed in all subjects. AF was diagnosed by ECG in 29 patients (18%). AF screening showed overall 86% sensitivity and 96% specificity. False negatives (n = 4) had RR-interval coefficient of variation lower than true positives (n = 25, p < 0.01), suggesting a regular ventricular rhythm during AF. The repeated evaluation substantially confirmed the same level of agreement. AF screening was positive in all patients with new-onset AF (n = 6, 100%). Systematic AF screening in patients admitted to Internal Medicine wards, performed using the Microlife WatchBP Office AFIB, is feasible and effective. The opportunity to implement such technology in daily routine clinical practice to prevent undiagnosed AF episodes in hospitalized patients should be the subject of further research.

scholarly journals Comparative study of the prevalence of sepsis in patients admitted to dermatology and internal medicine wards

2013 ◽  
Vol 88 (5) ◽  
pp. 739-747
Author(s):  
Luiz Mauricio Costa Almeida ◽  
Michelle dos Santos Diniz ◽  
Lorena dos Santos Diniz ◽  
Jackson Machado-Pinto ◽  
Francisco Chagas Lima Silva
Keyword(s):  
Internal Medicine ◽  
Comparative Study ◽  
Medical Records ◽  
Skin Barrier ◽  
Epidemiological Studies ◽  
Internal Medicine Ward ◽  
Cross Sectional ◽  
Systemic Corticosteroids ◽  
Internal Medicine Wards ◽  
Belo Horizonte

BACKGROUND: Sepsis is a common cause of morbidity and mortality among hospitalized patients. The prevalence of this condition has increased significantly in different parts of the world. Patients admitted to dermatology wards often have severe loss of skin barrier and use systemic corticosteroids, which favor the development of sepsis. OBJECTIVES: To evaluate the prevalence of sepsis among patients admitted to a dermatology ward compared to that among patients admitted to an internal medicine ward. METHODS: It is a cross-sectional, observational, comparative study that was conducted at Hospital Santa Casa de Belo Horizonte. Data were collected from all patients admitted to four hospital beds at the dermatology and internal medicine wards between July 2008 and July 2009. Medical records were analyzed for the occurrence of sepsis, dermatologic diagnoses, comorbidities, types of pathogens and most commonly used antibiotics. RESULTS: We analyzed 185 medical records. The prevalence of sepsis was 7.6% among patients admitted to the dermatology ward and 2.2% (p = 0.10) among those admitted to the internal medicine ward. Patients with comorbidities, diabetes mellitus and cancer did not show a higher incidence of sepsis. The main agent found was Staphylococcus aureus, and the most commonly used antibiotics were ciprofloxacin and oxacillin. There was a significant association between sepsis and the use of systemic corticosteroids (p <0.001). CONCLUSION: It becomes clear that epidemiological studies on sepsis should be performed more extensively and accurately in Brazil so that efforts to prevent and treat this serious disease can be made more effectively.

scholarly journals Prevalence of potential drug–drug interactions among internal medicine ward in University of Gondar Teaching Hospital, Ethiopia

2014 ◽  
Vol 4 ◽  
pp. S204-S208 ◽  
Author(s):  
Akshaya Srikanth Bhagavathula ◽  
Alemayehu Berhanie ◽  
Habtamu Tigistu ◽  
Yishak Abraham ◽  
Yosheph Getachew ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Drug Interactions ◽  
Teaching Hospital ◽  
Potential Drug ◽  
Internal Medicine Ward

scholarly journals The Prevalence of Alprazolam Uses in Geriatric Patients at Dr. Mohammad Hoesin Hospital Palembang

2016 ◽  
Vol 5 (2) ◽  
pp. 193
Author(s):  
Yohanes Febrianto ◽  
Sutomo Tanzil ◽  
Theodorus Parulian
Keyword(s):  
Internal Medicine ◽  
Heart Disease ◽  
Medical Records ◽  
Geriatric Patients ◽  
Age Group ◽  
Internal Medicine Ward ◽  
Drug Utilization Study ◽  
Short Acting ◽  
Infectious Origin ◽  
Male Patients

<p>One of the most frequently prescribed drugs in geriatric patients is a benzodiazepine, especially a short-acting such as alprazolam. Unfortunately, alprazolam is oftenly used inappropriately because this drug has a short acting effect. Geriatric patients are more sensitive to this drug that can lead to the dependence. However, there is still lack of data on the use of this drug in geriatric patients. The aim of this study was to determine the prevalence of the use of alprazolam. A drug utilization study has been done for 2 months through analysis of patient’s medical records in the internal medicine ward at RSMH Palembang from June 1<sup>st</sup>, 2012 to May 31<sup>st</sup>, 2013. There were 25 out of 1634 patients receiving alprazolam, but only 23 patients whose data were obtained from the available medical records. Prevalence of alprazolam use was 1.408%. Based on gender, the prevalence was 1.798% in female and 1.09% in male patients. Proportion by age group was 91.3%, 8.7% and 0% in age group 60-74 years, 75-90 years and over 90 years, respectively. Based on the job, the population study comprised of the housewive (52.1%), unemployment (39.1%), and entrepreneur and farmer (4.3% together). The indication of usage was atheroscerotic heart disease, diarrhoea and gastroenteritis of presumed infectious origin, unspecified gastritis, and thyrotoxic heart disease. In other words, it could be said that the usage of alprazolam was inappropriate.</p>

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