scholarly journals METHODS OF PREVENTING BIOFILMS FORMATION ON THE SURFACES OF POLYMER MATERIALS

Author(s):  
L. R. Lyusova ◽  
А. А. Ilyin ◽  
L. S. Shibryaeva

One of the harmful factors of the interaction of microorganisms with the technosphere is the formation of biofilms on the surface of various products. Steady colonies of bacteria ensure a stable contamination of the handling medium of the product, and their release is a cause of biodestructive processes in materials. In many cases, single or even regular antimicrobial treatment does not lead to complete suppression of colony formation. Therefore, today the most demanded methods of preventing biofilms formation involve the creation of materials that are resistant to colonization by bacteria. Since bacteria cells directly interact with the surface of the material, it is the surface that should have antibacterial properties. In the review, various methods of preventing the formation of biofilms by the example of polymeric materials are considered. The main attention is paid to the methods of creating antibacterial surfaces, which in various ways prevent the formation of biofilms. In accordance with the world practice, all antibacterial surfaces are divided into four types: releasing, contact-active, repelling and self-polishing. The advantages and disadvantages of each type of antibacterial surfaces, their existing limitations in use and prospects for further development are noted. Information on the compatibility of individual types of surfaces is also noted in the literature.

2020 ◽  
Vol 67 (2) ◽  
pp. 115-120
Author(s):  
Raisa A. Alekhina ◽  
Victoriya E. Slavkina ◽  
Yuliya A. Lopatina

The article presents options for recycling polymers. The use of biodegradable materials is promising. This is a special class of polymers that can decompose under aerobic or anaerobic conditions under the action of microorganisms or enzymes forming natural products such as carbon dioxide, nitrogen, water, biomass, and inorganic salts. (Research purpose) The research purpose is in reviewing biodegradable materials that can be used for the manufacture of products used in agriculture. (Materials and methods) The study are based on open information sources containing information about biodegradable materials. Research methods are collecting, studying and comparative analysis of information. (Results and discussion) The article presents the advantages and disadvantages of biodegradable materials, mechanical properties of the main groups of biodegradable polymers. The article provides a summary list of agricultural products that can be made from biodegradable polymer materials. It was found that products from the general group are widely used in agriculture. Authors have found that products from a special group can only be made from biodegradable polymers with a controlled decomposition period in the soil, their use contributes to increasing the productivity of crops. (Conclusions) It was found that biodegradable polymer materials, along with environmental safety, have mechanical properties that allow them producing products that do not carry significant loads during operation. We have shown that the creation of responsible products (machine parts) from biodegradable polymers requires an increase in their strength properties, which is achievable by creating composites based on them. It was found that the technological complexity of their manufacture and high cost are the limiting factors for the widespread use of biodegradable polymers at this stage.


2021 ◽  
Vol 7 (1) ◽  
pp. 31-40
Author(s):  
T. Radzievskaya ◽  
N. Ivanov ◽  
S. Tarasov

The article presents the development prospects of planar optical waveguides for high-speed data transmission systems optoelectronic buses by polymer materials. The advantages and disadvantages of using non-specialized polymeric materials for general use are revealed. The polymer planar optical waveguides fabrication technologies are proposed. The main losses types in planar optical waveguides, the reasons for their occurrence, as well as approaches to their reduction are determined. Using the example of PDMS polymer and soft lithography technology, the technological process critical stages of polymer planar optical waveguides production are noted, which contribute to an scattering losses increase. For each stage, algorithms are proposed to prevent an scattering losses increase. These algorithms were implemented in practice in the manufacture of layouts of polymer planar optical waveguides of the optical-electronic data transmission bus.


2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Irina N. Vikhareva ◽  
Evgeniya A. Buylova ◽  
Gulnara U. Yarmuhametova ◽  
Guliya K. Aminova ◽  
Aliya K. Mazitova

Plastic is one of the most demanded materials on the planet, and the increasing consumption of which contributes to the accumulation of significant amounts of waste based on it. For this reason, a new approach to the development of these materials has been formed: the production of polymers with constant operational characteristics during the period of consumption and capable of then being destroyed under the influence of environmental factors and being involved in the metabolic processes of natural biosystems. The paper outlines the prerequisites for the development of the field of creating biodegradable composite materials, as well as the main technical solutions for obtaining such polymeric materials. The main current solutions for reducing and regulating the degradation time of polymer materials are presented. The most promising ways of further development of the field of bioplastics production are described. Common types of polymers based on renewable raw materials, composites with their use, and modified materials from natural and synthetic polymers are considered.


Author(s):  
I.N. Vikhareva ◽  
I.I. Zaripov ◽  
D.F. Kinzyabulatova ◽  
N.S. Minigazimov ◽  
G.K. Aminova

One of the most demanded materials on the planet is plastic, the excellent performance of which contributes to the accumulation of a significant amount of waste on its basis. In this regard, a new approach to the development of these materials has been formed in scientific circles: the production of polymer composites with constant performance characteristics for a certain period and then capable of destruction under the influence of environmental factors. Analysis of the current state of the industry of polymeric materials shows that the most urgent is the use of such classical polymers as polyolefins and polyvinyl chloride. First of all, the optimal solution to this problem due to the lack of a suitable replacement for traditional polymers is the development of composites based on them with the use of biodegradable additives. In this case, a set of problems associated with waste disposal is solved: the decomposition period of the recycled waste is significantly reduced, the territories required for plastic waste are reduced. The paper outlines the preconditions for the emergence and further development of the field of biodegradable polymers. The main quantitative characteristics of the production capacities of manufactured bioplastics by types, regions and industries of application are given. Modern methods of reducing and regulating the degradation time of polymer materials are presented. The main global and domestic manufacturers of biodegradable polymers and their products are listed, as well as a list of the main manufacturers of biodegradable additives for polymeric materials. Modern types of bioplastics based on renewable raw materials, composites with their use, as well as modified materials from natural and synthetic polymers are listed. The main methods for determining the biodegradability of existing bioplastics are described


2018 ◽  
Vol 8 (3) ◽  
pp. 18-21
Author(s):  
Alexander A. PISHCHULEV ◽  
Ekaterina V. BLINKOVA ◽  
Sholpan N. MAKAROVA

A new type of formwork systems based on the use of BIM technologies and formwork sheets from polymeric materials for the erection of standard and individual building structures with a fi ne fi nish have been proposed. The statistical data on the development trend of monolithic housing construction in Russia and the world are given. The advantages and disadvantages of this technology are presented, it is shown how to deal with them. A system of paraffi n formwork has been proposed to facilitate restoration work, as well as works on the construction of architecturally expressive parts of the facades (moldings, sandriks, bulk compositions). An algorithm for working with it using spatial scanning of facades and 3D printing has been developed.


The main methods (pressing and winding) of the processing of hybrid polymer composites to obtain items were examined. Advantages and disadvantages of the methods were noted. Good combinations of different-module fibers (carbon, glass, boron, organic) in hybrid polymer materials are described, which allow one to prepare materials with high compression strength on the one hand, and to increase fracture energy of samples and impact toughness on the other hand.


2019 ◽  
Vol 2019 (3) ◽  
pp. 47-53
Author(s):  
Галина Глембоцкая ◽  
Galina Glembockaya ◽  
Станислав Еремин ◽  
Stanislav Eremin

In order to identify promising strategic development possibilities for the pharmaceutical industry in the Russian Federation, a pilot study was conducted, which has analyzed the main trends in the development of innovative medicines. As a result of the content analysis of available sources of scientific literature, the characteristics of options used in the world practice for increasing the innovative activity of individual subjects and the pharmaceutical market as a whole are presented. Possible reserves for the further development of the innovative component of the pharmaceutical market within the framework of the concept of personalized medicine according to the P4 principle (predictive - personalized - preventive - participatory) are identified and structured. The results of use by individual pharmaceutical companies of scientifically and practically justified approaches to optimizing the costs of development and promoting drugs are presented. The advantages and real prospects of a generally accepted method to reduce the cost of development by «expanding the pharmacological effect» (label expansion) of already existing drugs with a known safety profile in the world practice are shown. A scientific generalization and structuring of the goals and results of the post-registration phase of clinical trials to expand the pharmacological action of a number of drugs already existed at the market have been carried out.


2019 ◽  
Vol 17 (4) ◽  
pp. 225-239 ◽  
Author(s):  
Lulu Zuo ◽  
Ke Peng ◽  
Yihong Hu ◽  
Qinggang Xu

AIDS is a globalized infectious disease. In 2014, UNAIDS launched a global project of “90-90-90” to end the HIV epidemic by 2030. The second and third 90 require 90% of HIV-1 infected individuals receiving antiretroviral therapy (ART) and durable virological suppression. However, wide use of ART will greatly increase the emergence and spreading of HIV drug resistance and current HIV drug resistance test (DRT) assays in China are seriously lagging behind, hindering to achieve virological suppression. Therefore, recommending an appropriate HIV DRT method is critical for HIV routine surveillance and prevention in China. In this review, we summarized the current existing HIV drug resistance genotypic testing methods around the world and discussed the advantages and disadvantages of these methods.


Impact ◽  
2018 ◽  
Vol 2018 (3) ◽  
pp. 50-51
Author(s):  
Akinori Akaike

The Japanese Pharmacological Society (JPS) was established in 1927 with the express purpose of contributing to the further development of the field of pharmacology through the spread of scientific knowledge on pharmacological theory based on applied research conducted in close coordination with our fellow members as well as other affiliated academic societies throughout the world.


Author(s):  
Arnoud Arntz ◽  
Marleen Rijkeboer ◽  
Edward Chan ◽  
Eva Fassbinder ◽  
Alp Karaosmanoglu ◽  
...  

Abstract Background A central construct in Schema Therapy (ST) is that of a schema mode, describing the current emotional-cognitive-behavioral state. Initially, 10 modes were described. Over time, with the world-wide increasing and broader application of ST to various disorders, additional schema modes were identified, mainly based on clinical impressions. Thus, the need for a new, theoretically based, cross-cultural taxonomy of modes emerged. Methods An international workgroup started from scratch to identify an extensive taxonomy of modes, based on (a) extending the theory underlying ST with new insights on needs, and (b) recent research on ST theory supporting that modes represent combinations of activated schemas and coping. Results We propose to add two emotional needs to the original five core needs that theoretically underpin the development of early maladaptive schemas (EMSs), i.e., the need for Self-Coherence, and the need for Fairness, leading to three new EMSs, i.e. Lack of a Coherent Identity, Lack of a Meaningful World, and Unfairness. When rethinking the purpose behind the different ways of coping with EMS-activation, we came up with new labels for two of those: Resignation instead of Surrender, and Inversion instead of Overcompensation. By systematically combining EMSs and ways of coping we derived a set of schema modes that can be empirically tested. Conclusions With this project, we hope to contribute to the further development of ST and its application across the world.


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