scholarly journals EPIDEMIOLOGICAL STUDY OF SILICOSIS WITH BILATERAL SPONTANEOUS PNEUMOTHORAX IN RAJASTHAN

Author(s):  
Dr Nalin Joshi ◽  
Dr Ramakant Dixit

Background: Silicosis is reported to be an occupational lung disease, which is caused by the inhalation of silica dust. Workers in occupations related to silica dust exposure are characterized by increased foci of fibrogenesis which result in radiological and pathological findings in the lungs. In most circumstances silicosis only develops subsequent to substantial occupational exposures. Material & Methods: The present prospective study was conducted at department of respiratory medicine of our tertiary care hospital. The study was an observational study conducted during a period of one year. The study done at 95% confidence interval at 10% of maximum allowable error. All patients who were diagnosed with silicosis were enrolled into the study. Results: In the present study, all patient had cough at presentation out which 7 (70%) patients had dry cough and 3 patients with productive coughs, four patients experienced loss of appetite. Eight (80%) patients had a history of smoking. Chest X-rays of all patients revealed bilateral, widespread, reticulonodular, and nodular appearances. Six patients had work on crusher machine and four patients as manual stone cutter.  Pneumothorax was located bilaterally in all cases. Conclusion: We concluded from the present study that inhalation of quartz dust or silica dusts was commonly associated with adverse health effects and it can cause serious morbidity like secondary spontaneous pneumothorax and mortalities. Keywords: Silicosis, occupational lung disease, secondary spontaneous pneumothorax.

1999 ◽  
Vol 20 (02) ◽  
pp. 110-114 ◽  
Author(s):  
Deniz Akduman ◽  
Lynn E. Kim ◽  
Rodney L. Parks ◽  
Paul B. L'Ecuyer ◽  
Sunita Mutha ◽  
...  

AbstractObjective:To evaluate Universal Precautions (UP) compliance in the operating room (OR).Design:Prospective observational cohort. Trained observers recorded information about (1) personal protective equipment used by OR staff; (2) eyewear, glove, or gown breaks; (3) the nature of sharps transfers; (4) risk-taking behaviors of the OR staff; and (5) needlestick injuries and other blood and body-fluid exposures.Setting:Barnes-Jewish Hospital, a 1,000-bed, tertiary-care hospital affiliated with Washington University School of Medicine, St Louis, Missouri.Participants:OR personnel in four surgical specialties (gynecologic, orthopedic, cardiothoracic, and general). Procedures eligible for the study were selected randomly. Hand surgery and procedures requiring no or a very small incision (eg, arthroscopy, laparoscopy) were excluded.Results:A total of 597 healthcare workers' procedures were observed in 76 surgical cases (200 hours). Of the 597 healthcare workers, 32% wore regular glasses, and 24% used no eye protection. Scrub nurses and medical students were more likely than other healthcare workers to wear goggles. Only 28% of healthcare workers double gloved, with orthopedic surgery personnel being the most compliant. Sharps passages were not announced in 91% of the surgical procedures. In 65 cases (86%), sharps were adjusted manually. Three percutaneous and 14 cutaneous exposures occurred, for a total exposure rate of 22%.Conclusion:OR personnel had poor compliance with UP. Although there was significant variation in use of personal protective equipment between groups, the total exposure rate was high (22%), indicating the need for further training and reinforcement of UP to reduce occupational exposures.


2021 ◽  
Vol 6 (3) ◽  
pp. 183-187
Author(s):  
M Ravindranath ◽  
C H Raju

Chronic Obstructive Lung Disease (COPD) is a condition where there is poor airflow to the lungs and over a period of time this condition worsen, resulting in severe morbidity. L-carnitine (LC) is a soluble qaurtenary amine and is essential for the tissues and lung tone to function normally. This study was therefore find out the association of L-carnitine in patients with chronic Obstructive Pulmonary Disease. 75 patients who came to the Department of Pulmonology of either sex between 40 to 75 years with confirmed COPD were included into patients group and 75 healthy patients were included into the control group. Blood was collected for Fasting blood sugar, AST, ALP, ALT, Urea, Creatinine, Albumin, pre-albumin, iron , magnesium, sodium, phosphorous, calcium, Acylcarnitines, total and free carnitine levels. X-rays were taken and pulmonary function test was done for all the patients. The mean age of the patients in our study was 62.53 and 61.86 years among the patients and controls respectively. Among the controls the Ph and Fe levels were 3.1 ± 0.9mmol/L and 21.69 ± 3.19 mcg/dL respectively and among the patients the same levels were 2.6 ± 1.9mmol/L and 43.82 ± 8.22mcg/dL respectively. The albumin and the prealbumin in the patients were significantly lower in the patients with 21.81 ± 2.88 and 23.53 ±2.58 mg/dL and in controls they were 32.61 ±3.87 and 26.87 ± 1.93 mg/dL respectively. There was a considerable carnitine deficiencies in COPD patients when compared to the controls and since carnitine can be found in regular diet, people can be educated to have a proper intake of foods containing carnitine in their regular diet.


Author(s):  
Ajay Sharma ◽  
Ashok Sharma ◽  
Pramod Jaret ◽  
Malay Sarkar ◽  
Sanjeev Sharma

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">The spontaneous pneumothorax has been classified as major cause of morbidity and mortality among respiratory diseases. The objectives of the study were to determine the incidence and aetiology of spontaneous pneumothorax and to assess the clinical profile of affected patients admitted in our institute</span>.</p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">A hospital based prospective study was conducted in year 2011-12 in the Department of Medicine, IGMC Shimla (H.P.) India. During study period the total admissions were 7335 out of which 30 patients were diagnosed as spontaneous pneumothorax and treated as cases under study. The data was collected on proforma includes demographic profile, probable cause, clinical and outcome indicators of Spontaneous Pneumothorax, master chart framed and analysed into frequency percentage. </span><span lang="EN-IN"> </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Incidence of spontaneous pneumothorax was found to be 408.99/yr/100000 admissions in the department of medicine. Incidence of primary spontaneous pneumothorax was 81.79/yr/100000 admissions. Incidence of secondary spontaneous pneumothorax was 327.19/yr/100000 admissions. Majority of the patients of primary spontaneous pneumothorax were of the 20-29yrs age group. Higher proportions of cases were from male gender (93.33%). Secondary pneumothorax patients were mostly of 50 to 59 years age group. The predominant aetiology for secondary spontaneous pneumothorax was COPD (36.66%) followed by Pulmonary tuberculosis (33.33%)</span>.</p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Spontaneous pneumothorax was more common in men. The predominant aetiology for secondary spontaneous pneumothorax was COPD (36.66%) followed by pulmonary tuberculosis (33.33%). </span></p><p class="abstract"> </p>


2007 ◽  
Vol 28 (7) ◽  
pp. 774-782 ◽  
Author(s):  
Emily M. O'Malley ◽  
R. Douglas Scott ◽  
Julie Gayle ◽  
John Dekutoski ◽  
Michael Foltzer ◽  
...  

Objective.To determine the cost of management of occupational exposures to blood and body fluids.Design.A convenience sample of 4 healthcare facilities provided information on the cost of management of occupational exposures that varied in type, severity, and exposure source infection status. Detailed information was collected on time spent reporting, managing, and following up the exposures; salaries (including benefits) for representative staff who sustained and who managed exposures; and costs (not charges) for laboratory testing of exposure sources and exposed healthcare personnel, as well as any postexposure prophylaxis taken by the exposed personnel. Resources used were stratified by the phase of exposure management: exposure reporting, initial management, and follow-up. Data for 31 exposure scenarios were analyzed. Costs were given in 2003 US dollars.Setting.The 4 facilities providing data were a 600-bed public hospital, a 244-bed Veterans Affairs medical center, a 437-bed rural tertiary care hospital, and a 3,500-bed healthcare system.Results.The overall range of costs to manage reported exposures was $71-$4,838. Mean total costs varied greatly by the infection status of the source patient. The overall mean cost for exposures to human immunodeficiency virus (HIV)-infected source patients (n = 19, including those coinfected with hepatitis B or C virus) was $2,456 (range, $907-$4,838), whereas the overall mean cost for exposures to source patients with unknown or negative infection status (n = 8) was $376 (range, $71-$860). Lastly, the overall mean cost of management of reported exposures for source patients infected with hepatitis C virus (n = 4) was $650 (range, $186-$856).Conclusions.Management of occupational exposures to blood and body fluids is costly, the best way to avoid these costs is by prevention of exposures.


2007 ◽  
Vol 23 (3) ◽  
pp. 125-132 ◽  
Author(s):  
Iraj Mohebbi ◽  
Isa Abdi Rad

Background: A secondary spontaneous pneumothorax is a complication of an underlying pulmonary disease. In recent years, there have been only a few scattered reports of patients with silicosis also having a pneumothorax. Silicosis, a form of disabling pulmonary fibrosis, is a well-known occupational disease resulting from high-level exposure to silica or silica-containing dusts. The objective of the present study was to elucidate any associations between the occurrence of a pneumothorax, and pulmonary function tests and clinical observations performed prior to the pneumothorax; these two factors may be predictors for a pneumothorax among workers exposed primarily to silica-containing respirable dust. Methods: A diagnosis of silicosis was made on several factors: silica dust exposure, appropriate interval of time after exposure, clinical findings, pulmonary function tests and chest radiological findings. A checklist was designed for collecting data of occupational history, respiratory signs, and symptoms from onset of dust exposure to the occurrence of a pneumothorax. Spirometery was conducted in accordance to the recommendations of standard protocols and guidelines posited by the American Thoracic Society. Autopsies were performed in three cases where the patient had suffered a pneumothorax due to silicosis. Mann—Whitney U-tests and Fisher's exact tests were used to determine any associations between pneumothorax and predictor factors. Results: An association between a progressive decrease in pulmonary function test values and a pneumothorax was observed. The occurrence of a pneumothorax was associated with complaints of pleuretic chest pain, resting dyspnea, respiratory distress, paroxysmal nocturnal dyspnea, orthopnea and crackle. Conclusion: A characteristic decline in pulmonary function test values and the severity of respiratory impairment may facilitate the occurrence of a pneumothorax in silicosis. Toxicology and Industrial Health 2007; 23: 125—132.


Author(s):  
Dr. Mukesh Kumar Mandawariya ◽  
Dr. Nalin Joshi ◽  
Dr. S.P. Agnihotri ◽  
Rekha Mandawariya

Background: Primary spontaneous pneumothoraces (PSP) affect patients who do not have clinically apparent lung disorders.  Secondary pneumothoraces occur in the setting of underlying pulmonary disease.  Methods: A total of 100 patients, including both males and females, admitted during the given period to the hospital with a diagnosis of spontaneous Pneumothorax (SP) were included in the study after applying to the inclusion and exclusion criteria. Results: COPD was the most common cause (45.6%) followed by Tuberculosis (30%). Silicosis was seen in 18.9% of SSP cases. Other less common causes were Bronchiectasis (3.3%), Pneumonia (1.1%) and Malignancy (1.1%). Conclusion:  Secondary spontaneous pneumothorax is far more common than primary spontaneous pneumothoraces and COPD is the predominant underlying cause of secondary spontaneous pneumothorax followed by pulmonary tuberculosis. We also found that silicosis is a significant contributor to secondary spontaneous pneumothorax, after COPD and pulmonary tuberculosis. Keywords: COPD, TB, Etiology


Lung India ◽  
2015 ◽  
Vol 32 (4) ◽  
pp. 415
Author(s):  
ArunabhaDatta Chaudhuri ◽  
Susmita Kundu ◽  
SumitRoy Tapadar ◽  
Sourin Bhuniya ◽  
Bijan Ghosh ◽  
...  

2017 ◽  
Vol 4 (6) ◽  
pp. 1547 ◽  
Author(s):  
Rishi K. Sharma ◽  
Atul Luhadia ◽  
Shanti K. Luhadia ◽  
Yash Mathur ◽  
Harshil Pandya ◽  
...  

Background: Silicosis is an occupational lung disease caused by inhalation of dust containing crystalline silica particles of size 0.5-5 microns in diameter. It commonly occurs in workers involved in quarrying, mining, sandblasting, tunneling, foundry work and ceramics. Pneumothorax is one of the complications of silicosis. The occurrence of pneumothorax in a patient with silicosis is a rare event, but it may be fatal. The incidence of secondary spontaneous pneumothorax (SSP) in silicosis as such is not known. This study aims to report the cases of secondary spontaneous pneumothorax in patients of silicosis in Southern part of Rajasthan.Methods: 50 patients of silicosis established by historical, clinical evaluation and radiological evidence with increased dyspnoea were included in the study. In all patients Chest X ray was done immediately.Results: Among 50 patients of silicosis with increased dyspnoea, Chest X ray showed pneumothorax in 20 patients of which 4 had bilateral pneumothorax, 7 had right pneumothorax and 9 had left pneumothorax. The mean duration of exposure to silica particles was 10 years (5 to 15 years). All the patients had various degrees of dyspnoea and chest pain. Tube thoracostomy was performed in 15 patients while 5 patients were managed conservatively with oxygen and bronchodilators.Conclusions: Our study showed an increased incidence of secondary pneumothorax in silicosis patients. The occurrence of pneumothorax, though rare in silicosis is a potentially life-threatening complication and may cause serious morbidity and mortality. The patients of silicosis who develop sudden onset of dyspnoea should be promptly investigated for this complication.


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