scholarly journals A STUDY TO ASSESS KNOWLEDGE ATTITUDE AND PRACTICES OF PHARMACOVIGILANCE AMONGST SECOND YEAR MEDICAL STUDENTS OF A TEACHING HOSPITAL IN NORTH MAHARASHTRA.

Author(s):  
Smita Avhad ◽  
Jeetendra Singh ◽  
Sakshi Mishra

Pharmacovigilance (PV) plays a vital role in the healthcare system through assessment, monitoring and discovery of interactions amongst drugs and their effects in human. Medicines do come with their respective adverse effects.  Therefore it is imperative to do Adverse Drug Reaction (ADR) monitoring while they are being marketed. PV is a part of the second MBBS curriculum, but often given less importance by the students. If this Knowledge Attitude & Practice of PV can be made effective during the MBBS course itself, it may make the students better aware about ADR monitoring. Aims & Objective: Our purpose was to find out the knowledge, attitude & practices amongst the second year medical students in a tertiary care hospital in North Maharashtra. Methods: This was an observational based study which had predesigned questions. After seeking the approval from the Institutional Ethics Committee, questionnaire was given to second year students of a tertiary care hospital in north Maharashtra. MS Excel was used for data analysis. Results:  The overall response rate was 76%. 30% answered knowledge question correctly whereas 70% answered the attitude questions correctly. Only 4 % had reported an ADR and majority felt that busy duty hours and fear of legal action was the reason for underreporting. Conclusion: Our study revealed that in spite of PV being part of 2nd year MBBS, it still needs more emphasis and attention. The   student feedback regarding ADR after they visit wards may help in improving the general awareness. Keywords: Pharmacovigilance, Knowledge, Attitude, ADR.

Children ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. 282
Author(s):  
Alina Grama ◽  
Cornel Olimpiu Aldea ◽  
Lucia Burac ◽  
Dan Delean ◽  
Bogdan Bulata ◽  
...  

Background: Acute liver failure (ALF) is a rare disease, associated with high mortality, despite optimal medical therapy without emergency liver transplantation. Knowing the possible cause of ALF plays a vital role in the management, as the child could benefit from effective specific therapies in emergencies. Methods: We have analyzed the etiology and outcome of ALF in children followed-up in a tertiary care hospital between January 2012–December 2018. The patients were grouped into different age categories: neonates (0–1 month), infants (1–12 months), children (1–14 years), and teenagers (14–18 years). Results: 97 children (46 males, 47.42%, the mean age of 7.66 ± 8.18 years) were admitted with ALF. The most important causes of ALF were in neonates and infants, infections (72.72%), and metabolic disorders (43.47%), in children and adolescents were the toxic causes (60% and 79.41%). The mortality rate was 31.95% (31 patients), mainly in ALF due to infections or metabolic disorders. Conclusions: In neonates and infants, the main causes of ALF were infections and metabolic diseases, while in older children and teenagers, were toxin-induced liver injuries. The mortality among neonates and infants was significantly higher than in other ages. Early recognition and immediate therapeutic intervention could improve the outcome of these patients.


Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 5294-5294
Author(s):  
Dharma R. Choudhary ◽  
Rajat Kumar ◽  
R. Saxena ◽  
Manoranjan Mahapatra ◽  
Atul Kotwal ◽  
...  

Abstract Background: There is very little published epidemiological data from developing countries regarding ITP and no large series from India. The aim of the study was to analyze the presenting features, response to different therapeutic options and suggest cost effective therapy. Method: The records of hematology department of All India Institute Of Medical Science were analyzed from January 1992 to June 2004. This is a premium tertiary care hospital in India. Diagnosis of ITP was made according to the standard criteria. Response criteria: complete response was defined as a platelet count increase to 100x109 /l or more, for at least 2 months: partial response was defined as doubling of platelet counts from initial levels and > 50x 109/l for at least 2 months; no response included none of the above. Statistical methods: Database was created in MS Access and SPSS ver 11 was used for statistical analysis. Descriptive statistics were calculated and appropriate tests of significance like Chi Square, repeated measure linear model were carried out. Results: During the study period, 1230 patients of ITP were seen in hematology department, with a median age of 19.6 years (range 0.9–80). Females were 51.1% and males 48.9%. Median follow-up was of 9 months (range 0–178). Presenting features were: skin bleed − 91.1%; mucosal bleed − 57.5%; hematuria − 7.2%; gastrointestinal bleed − 12.5% and intracraniall bleed − 2.8%. Per-vaginal bleeding − 31.2 % of females. History of preceding viral fever was seen in 13.1% and palpable spleen in 2.5%. The mean platelet counts at presentation were 34+ 18.3x109/l. There were 595 (48.4%) patients of acute ITP and 635 (51.6%) patients of chronic ITP. Childhood ITP (age ≤ 12 yr) was seen in 46.5% and adult ITP in 53.5%. Response to therapy: Prednisolone was given to 99.6% patients with response of 57.3 %; Intravenous gamma globulin was given to 8.9% with response in 63.6%. Splenectomy was performed in 5% of acute ITP and 15.1% of chronic ITP (p = 0.00). The overall number of splenectomies was 126, with a response rate of 83.3%. Of these 126, acute ITP constituted 23.8% while chronic ITP formed 76.2% of cases. There was no statistically significant difference in response rate in these two groups (p =0.575). Danazole was given to 66 patients with response in 44%. Various other modalities of treatment were given to 24 patients (Anti D-14; Dapsone-2; Cyclosporin-2; Azathioprine-5; and Vincristine with Cyclophosphamide -1 patient), with a response in 25% of patients. The overall response rate with all treatment modalities was 68%: in childhood ITP − 65% and in adult ITP − 70.5%. Childhood ITP did not respond as expected, possibly due to referral bias of more refractory cases being referred to the center. The values of platelets showed a continuous increase during follow up and this increase was statistically significant (P=0.000 for all, Repeated measure model). Conclusion: Pattern of ITP in India is similar to that seen in other centers. In this study Prednisolone was given as first line agent to almost all patients with response in 57.3%; Splenectomy were done in 10.2% of prednisolone refractory or dependent patients with a response in 83.3%. These should form the primary modalities of therapy in developing countries. Significant numbers of patients were refractory to above-mentioned modalities and thus there is a requirement for other cost-effective therapies.


Author(s):  
Raj Lavadi ◽  
Mangala Subramanian ◽  
Meghana Panchaseelan ◽  
Lakshmi Chintala ◽  
Lalasa Reddy ◽  
...  

Background: Internet usage is prevalent among medical students as they utilize it for both study purposes as well as for entertainment. Widespread usage of the internet may lead to its addiction. The objective of the study was to determine the prevalence of internet addiction and identify its contributing factors among medical students.Methods: 239 second and third year medical students completed the internet addiction test as well as the supplementary questionnaire at Vydehi institute of medical sciences and research center. The assessment of addiction was performed using Dr. Kimberley Young's internet addiction test.Results: It was found that 120 (50.2%) students were mildly addicted and 39 (16.3%) students were moderately addicted and 1 (0.42%) student was severely addicted.Conclusions: 66.9% of medical students had various levels of internet addiction from mild to severe. Therefore, behavior change communication is required to overcome addiction in these students. 


Author(s):  
Roshi . ◽  
Vishal R. Tandon

Abstract: Transfusion by blood and blood products forms an important part of treatment. But this is not free from transfusion reactions which may be in the form of fever, rashes, shivering, anaphylaxis or even death. Hemovigilance is a programme of reporting such events.Materials and Methods: The present study was conducted in a tertiary care hospital of Jammu, (J& K). Permission was taken from Institutional Ethics Committee, Govt. Medical College, Jammu. A pretested questionnaire was prepared and circulated among practitioners. They were given time of 15 minutes to fill that questionnaire. After 15 minutes, the filled questionnaire were collected and were analysed. The data was presented in tabulated form.Results: Total 50 practitioners were included in the study. All the practitioners had knowledge about transfusion reactions. Only 10% of the practitioners had knowledge that transfusion reactions can be prevented, 40% of the practitioners had knowledge about hemovigilance programme and had an idea that transfusion reactions can be reported. But only 10% of the practitioners knew where to report and who can report, 6% knew how to report. Only 48% of the practitioners thought that transfusion reactions should be reported, 70% of the practitioners thought that transfusion reactions can be dangerous. 40% of practitioners told that seminars/CMEs should be planned. 80% of practitioners had encountered transfusion reactions, but only 2% had documented the same. 10% of the practitioners had attended seminars, CMEs. Many reasons were quoted for not reporting transfusion reactions.Conclusion:  Overall, most of the practitioners have a positive attitude towards transfusion reaction reporting but knowledge regarding the haemovigilance concept is poor and the majority of them never reported such reaction. Hence, our study demands increased awareness and continued training to strengthen the haemovigilance system.


Author(s):  
Amullya C. Pednekar ◽  
Padma N. Bhandare ◽  
Shantadurga S. Kerkar

Background: Management of medical ailments requires sound knowledge of diseases and drugs. Medical students are more likely to practice self-medication due to easy access to information. Inappropriate and inadequate treatment can lead to morbidity and mortality. Thus, the current study was carried out to understand the perception and practice of self-medication in medical students so that habit of ethical practice can be inculcated in them.Methods: A self-developed and prevalidated questionnaire was distributed amongst 145 students of second MBBS after approval from Institutional ethics Committee. Data was collected; analysed using MS Excel and the results were expressed as counts and percentages.Results: In this study authors noted 136 (93.79%) out of the 145 students practised self-medication. The commonest reason being effectiveness of medications for similar conditions in the past 92 (69.17%). 111 (81.61%) students reported fever as the most common indication. Analgesics/anti-pyretics 117 (86.02%) were the most frequently used drug groups. Majority 87 (63.97%) obtained information from friends and relatives. Adverse effects of self-medication were noted in 20 (14.70%).Conclusions: This study indicates higher prevalence of self-medication in medical students of Goa. Students can be sensitised and made aware about possible adverse effects and drug interactions with self-medication and how simple looking illness may take an ugly turn. Students being future doctors will continue this chain of spread of awareness of self-medication. Easy access to healthcare can also solve these problems.


2020 ◽  
pp. 48-50
Author(s):  
Dipsikha Das ◽  
Kalpana Gohain

Introduction: Self medication is referred to the use of medications to treat self-diagnosed disorders or symptoms without a valid prescription. Self medication practice is seen widely due to availability of over the counter drugs and lack of awareness of adverse drug reactions. Aims and Objectives: To study the knowledge, attitude and practice of self medication for diarrhoea among undergraduate medical students in a tertiary care hospital of Assam. Materials and methods: A cross-sectional questionnaire based study was carried out among the Undergraduate medical students of Assam Medical College & Hospital, Dibrugarh. The questionnaire was designed to assess the Knowledge, attitude and practice of self-medication for diarrhoea. A total of 130 students were included in the study after obtaining written informed consent from them. The data of the completely filled up questionnaire was analyzed and presented as mean and percentage. Results: Out of 130 students 89.23% practised self-medication for diarrhoea. The most common cause of self medication practice was to save time and source of information was from medical textbooks. The most common source of medicines was medical stores and commonly used drugs for diarrhoea were ORS, Metronidazole, Ofloxacin, probiotics and anti-motility drugs. Only 17.25% of students had awareness of the harmful effects of self medication for diarrhoea. Conclusion: There is high prevalence of self-medication practice to treat diarrhoea among undergraduate medical students which necessitates proper education and awareness regarding the benefits and hazards associated with self medication practice.


2021 ◽  
Vol 59 (236) ◽  
Author(s):  
Priyanka Shah ◽  
Alisha Sapkota ◽  
Anjeel Chhetri

Introduction: Medical students are prone to develop stress, anxiety and depression owing to vastness of curriculum, hectic lifestyle, economic burden, and competitiveness of medical field. The study aims to find out the prevalence of depression, anxiety, and stress among first-year medical students. Methods: A descriptive cross-sectional study was conducted among 91 first-year students of Bachelor of Medicine and Bachelor of Surgery enrolled in a tertiary care hospital using depression, anxiety, and stress-42 scale along with a questionnaire regarding sociodemographic and stressors for their problems. Whole sampling was done and the study was conducted between June and July 2018 after taking ethical approval from the Research and Institutional Review Committee (Reference Number: 57-074/075). Results: The highest prevalence among undergraduate medical students was found to be anxiety 54 (59.3%), followed by stress 41 (45.1%) and depression 40 (44%). Conclusions: Almost half of the first-year medical students reported some level of depression, anxiety, or stress. It is important to implement programs in the early years of the medical school from the administrative level to help and identify students suffering from depression, anxiety, and stress.


2020 ◽  
Vol 7 ◽  
pp. 238212052096303
Author(s):  
John Holten ◽  
Karthika Ramakrishnan ◽  
Abbas Charlie ◽  
Taylor Standiford ◽  
Hillel Maresky ◽  
...  

The COVID-19 pandemic has created unprecedented challenges in healthcare including pressure to provide efficient and timely patient care while maintaining a safe environment for physicians and staff. Radiology plays a vital role as part of a multidisciplinary team in the care of these patients. We address the experiences of our radiology residency at a large urban US academic institution with an underserved population in our fight against COVID-19. The unprecedented challenges faced during this pandemic has created monumental impacts on our training and allowed for development of skills and resources in order to better handle future situations.


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