scholarly journals Treatments for Parasitic Diseases Based on Rational Prescribing of Drugs according to Avicenna’s Approach

2021 ◽  
Vol 10 (4) ◽  
pp. 340-353
Author(s):  
Seyyed Amir Hosein Latifi‌ ◽  
◽  
Ali Reza Niknafs ◽  
Keyword(s):  
Clinical Symptoms ◽  
Study Data ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Rational Prescribing ◽  
Iranian Traditional Medicine ◽  
Control And Prevention ◽  
Immunological Diseases ◽  
Review Study ◽  
Parasitic Worms

Objective: Infections caused by parasitic worms are among the most common diseases in the world. Considering the parasitic infections resistant to treatment, drug side effects and the emergence of new immunological diseases, it seems more necessary to pay attention to the views and therapeutic experiences of physicians in Iranian Traditional Medicine (ITM). Methods: As A review study, data related to parasitic diseases and worms were first collected from Avicenna’s the Canon of Medicine book and other ITM books, and then underwent content analysis. Avicenna’s approach in the treatment of these diseases was studied based on the rational prescribing model. Results: Avicenna’s approach in the treatment of parasitic diseases is based on problem-solving model and according to the summary of patients’ conditions in terms of disease severity and prioritization of causes. It varies from person to person. Conclusion: Awareness of the causes of parasitic diseases, categorization of their clinical symptoms based on ITM, knowledge of natural and herbal medicine and various methods of prescribing them according to the health principals along with diagnostic and therapeutic methods of classic medicine can be helpful in control and prevention of parasitic diseases.

Częstość występowania robaczyc u dzieci w wieku przedszkolnym ? określenie czynników predysponujących

2018 ◽  
Vol 21 (4) ◽  
Author(s):  
Piotr Kaleta ◽  
Marta Palacz-Wróbel ◽  
Łukasz Chajec
Keyword(s):  
Statistical Data ◽  
Predisposing Factors ◽  
The Body ◽  
Personal Hygiene ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Frequency Of Occurrence ◽  
The World ◽  
Parasitic Worms ◽  
The Impact

Introduction. Parasitic diseases are common and pose threats to the health and lives of people around the world. Globally improving sanitary conditions also do not provide a sufficient method of preventing the parasitic infections that trigger them. Statistical data show a huge rate of parasitism in the world and a very large share of parasitic diseases in the number of deaths. Worms among pre-school children are quite common to a certain extent, and factors that favor them ? if properly identified, can be significantly reduced. This paper presents the frequency of occurrence of worms in this age range compared to statistical data and a list of factors predisposing the occurrence of these diseases. Aim. The aim of the study was to assess the frequency and predisposing factors for the occurrence of helminthia among children in pre-school age in Poland. Material and methods. An original questionnaire was used to conduct the research. Results. The frequency of occurrence of worms reaches about 10% of confirmed infections. The most common prevalence among children is oatosis. The most important factors predisposing to parasitic worms infection are: inadequate personal hygiene, inadequate food hygiene and its preparation, the impact of places with higher risk of infection (sandpits, playgrounds, kindergartens, nurseries, orphanages). Invasions, when the massiveness of parasite invasions is not large enough, often goes asymptomatically ? that is why the parent's perceptiveness and knowledge about the basic symptoms of the most common worms play a key role. The level of parents’ knowledge and awareness of the risk of being infected with parasitic worms is high. Most of the parents surveyed correctly diagnosed symptoms performed tests for the presence of parasites in the body of their children. Conclusions. Elimination of predisposing factors significantly minimizes the occurrence of helminthiasis.

scholarly journals Hyperlipidemia and the Role of Blood Lipids According to Iranian Traditional Medicine

2021 ◽  
Vol 11 (2) ◽  
pp. 128-139
Author(s):  
Alireza Niknafs ◽  
◽  
Mohamad Reza Rezvanfar ◽  
Mehdi Salehi ◽  
◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Clinical Symptoms ◽  
Therapeutic Interventions ◽  
Compensatory Response ◽  
Laboratory Findings ◽  
Iranian Traditional Medicine ◽  
Wide Range ◽  
Natural Remedies ◽  
Review Study

Objective: The first and most common cause of death in the world is due to cardiovascular diseases, and hyperlipidemia is one of the important and a critical controllable risk factors for these diseases. The connection between fat metabolism and a wide range of diseases, side effects of chemical drugs, and the increasing attention to the use of natural remedies reveal the necessity of further attention to the viewpoints of other schools of medicine, including complementary medicine. This review study aims to interpret hyperlipidemia from the perspective of Iranian Traditional Medicine (ITM). Methods: This is review study conducted based on a library method using the keywords related to hyperlipidemia to collect data through searching in online databases and ITM books. The data were analyzed based on the content analysis method. Results: Hyperlipidemia is mainly diagnosed by laboratory findings and often have no clear clinical symptoms. According to ITM, for diagnosing hyperlipidemia, attention should be paid to the role of liver, heart, and stomach along with the health principles and quadruple digestion. Conclusion: Hyperlipidemia is a condition that can be either pathological or physiological. According to ITM, it occurs due to the imbalance of humors inside the arteries and leads to higher blood concentration and. In some cases, it can be due to a disease and in some cases, it can be caused by the body’s compensatory response. Paying attention to the views of ITM can be effective in preventing disease and improving therapeutic interventions.

scholarly journals A review of the most important medicinal herbs affecting giardiasis

2019 ◽  
Vol 8 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Mohamad Reza Nazer ◽  
Saber Abbaszadeh ◽  
Khatereh Anbari ◽  
Morteza Shams
Keyword(s):  
Medicinal Plants ◽  
Clinical Symptoms ◽  
Artemisia Annua ◽  
Epigastric Pain ◽  
Punica Granatum ◽  
Parasitic Infections ◽  
Lavandula Stoechas ◽  
Iranian Traditional Medicine ◽  
The World ◽  
Effective Drugs

Infection due to the protozoa giardia is one of the most common parasitic infections in the world. Millions of people across the world acquire this infection each year. The most common clinical symptoms of giardiasis include abdominal pain, bloating and diarrhea, indigestion, epigastric pain, nausea, vomiting, and oily feces with bad smell. Drugs used for giardiasis lead to certain side effects, such as unpleasant taste in the mouth, gastrointestinal discomfort, nausea, headache and leukopenia. Considering the importance of giardiasis infection, it is essential to identify anti-parasitic herbal drugs to eliminate cystic and trophozoite types of this disease. Hence, this article is aimed to report the medicinal plants that are used in Iranian traditional medicine against giardiasis. The information in this review study was obtained from scientific articles indexed in databases such as ISI, PubMed, Scopus, SID, Magiran and Google Scholar that were retrieved using the search terms giardia, protozoa, herbs, extracts and essential oils. Medicinal plants such as Lavandula stoechas, Ferula assa-foetida, Tanacetum parthenium, Allium paradoxum, Chenopodium botrys, Carum copticum, Allium sativum, Artemisia annua, Allium ascalonicum, ZizIphora clinopodioides, Zataria multiflorahad, Eucalyptus globulus, Lippia beriandievi, Punica granatum are among the most important herbs used in Iranian herbal medicine as anti-giardiasis agents. These herbs are good candidates to produce natural and effective drugs for giardia.

Recent Advances in the Development of Broad-Spectrum Antiprotozoal Agents

2020 ◽  
Vol 27 ◽  
Author(s):  
Antonio Moreno-Herrera ◽  
Sandra Cortez-Maya ◽  
Virgilio Bocanegra-Garcia ◽  
Bimal Krishna Banik ◽  
Gildardo Rivera
Keyword(s):  
Giardia Lamblia ◽  
Heterocyclic Compounds ◽  
Trichomonas Vaginalis ◽  
Mechanisms Of Action ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Pharmacological Treatments ◽  
Preclinical Development ◽  
Leishmania Spp ◽  
Effective Drugs

: Infections caused by Trypanosoma brucei, Trypanosoma cruzi, Leishmania spp., Entamoeba histolytica, Giardia lamblia, Plasmodium spp., and Trichomonas vaginalis, are part of a large list of human parasitic diseases. Together, they cause more than 500 million infections per year. These protozoa parasites affect both low- and high-income countries and their pharmacological treatment is limited. Therefore, new and more effective drugs in preclinical development could improve overall therapy for parasitic infections even when their mechanisms of action are unknown. In this review, a number of heterocyclic compounds (diamidine, guanidine, quinoline, benzimidazole, thiazole, diazanaphthalene, and their derivatives) reported as antiprotozoal agents are discussed as options for developing new pharmacological treatments for parasitic diseases.

scholarly journals Application of Dendrimers for Treating Parasitic Diseases

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 343
Author(s):  
Veronica Folliero ◽  
Carla Zannella ◽  
Annalisa Chianese ◽  
Debora Stelitano ◽  
Annalisa Ambrosino ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Water Solubility ◽  
Parasitic Infection ◽  
Three Dimensional ◽  
Medical Knowledge ◽  
High Ratio ◽  
Molecular Volume ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Wide Range

Despite advances in medical knowledge, parasitic diseases remain a significant global health burden and their pharmacological treatment is often hampered by drug toxicity. Therefore, drug delivery systems may provide useful advantages when used in combination with conventional therapeutic compounds. Dendrimers are three-dimensional polymeric structures, characterized by a central core, branches and terminal functional groups. These nanostructures are known for their defined structure, great water solubility, biocompatibility and high encapsulation ability against a wide range of molecules. Furthermore, the high ratio between terminal groups and molecular volume render them a hopeful vector for drug delivery. These nanostructures offer several advantages compared to conventional drugs for the treatment of parasitic infection. Dendrimers deliver drugs to target sites with reduced dosage, solving side effects that occur with accepted marketed drugs. In recent years, extensive progress has been made towards the use of dendrimers for therapeutic, prophylactic and diagnostic purposes for the management of parasitic infections. The present review highlights the potential of several dendrimers in the management of parasitic diseases.

scholarly journals The state of art of neutrophil extracellular traps in protozoan and helminthic infections

2019 ◽  
Vol 39 (1) ◽  
Author(s):  
César Díaz-Godínez ◽  
Julio C. Carrero
Keyword(s):  
Neutrophil Extracellular Traps ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Helminth Parasites ◽  
Extracellular Traps ◽  
Helminthic Infections ◽  
Bacteria And Fungi ◽  
Net Release

AbstractNeutrophil extracellular traps (NETs) are DNA fibers associated with histones, enzymes from neutrophil granules and anti-microbial peptides. NETs are released in a process denominated NETosis, which involves sequential steps that culminate with the DNA extrusion. NETosis has been described as a new mechanism of innate immunity related to defense against different pathogens. The initial studies of NETs were carried out with bacteria and fungi, but currently a large variety of microorganisms capable of inducing NETs have been described including protozoan and helminth parasites. Nevertheless, we have little knowledge about how NETosis process is carried out in response to the parasites, and about its implication in the resolution of this kind of disease. In the best case, the NETs entrap and kill parasites in vitro, but in others, immobilize the parasites without affecting their viability. Moreover, insufficient studies on the NETs in animal models of infections that would help to define their role, and the association of NETs with chronic inflammatory pathologies such as those occurring in several parasitic infections have left open the possibility of NETs contributing to pathology instead of protection. In this review, we focus on the reported mechanisms that lead to NET release by protozoan and helminth parasites and the evidence that support the role of NETosis in the resolution or pathogenesis of parasitic diseases.

scholarly journals Actual problems of assessing the quality of disinfection measures for parasitosis in the Russian Federation

2020 ◽  
Vol 99 (3) ◽  
pp. 274-278
Author(s):  
М.М. M. Асланова ◽  
Т.В. V. Гололобова ◽  
К.Ю. Yu. Кузнецова ◽  
А.В. V. Загайнова ◽  
Тамари Резоевна Мания ◽  
...  
Keyword(s):  
Russian Federation ◽  
Professional Community ◽  
Parasitic Infections ◽  
Neglected Diseases ◽  
Parasitic Diseases ◽  
Anthropogenic Pressure ◽  
Difficult Situation ◽  
The Russian Federation ◽  
Parasitic Pathogens

Introduction. The main and the most significant issues of the management of disinfection measures taking into account modern trends and factors affecting the quality of these measures in relation to parasitic infections in the territory of the Russian Federation are considered. The professional community of physicians, epidemiologists, hygienists, disinfectants was almost powerless in the fight against slow or latent infections of a parasitic nature, which are still ca lled “neglected diseases” (“unnoticed diseases”), partly because they occur without pronounced symptoms, and there are a number of unresolved problems in the prevention and diagnosis. Despite the fact that modern medicine in the field of prevention and diagnosis of some infectious diseases has achieved good results, the problems with the disinfection of parasitic pathogens remain relevant. Environmental degradation, various natural disasters, urbanization, increased anthropogenic pressure, as well as climate change do not contribute to improving the difficult situation with regard to the spread, reproduction and formation of new stable foci of parasites. The measures for the improving the system of non-specific prevention of parasitic diseases are determined. Material and methods. In the course of the work, there were analyzed statistical reports of the Federal Reserve and the literature data. Results. The analysis of statistical data showed that during 2014-2018, the incidence of parasites in the Russian population remained at a high level and did not have a pronounced tendency to decrease, and the proposed anti-parasitic disinfectants cannot meet modern anti-epidemiological and hygienic requirements. Conclusion. A number of recommendations and initiatives on disinfection measures for the prevention and spread of parasitic infections in the territory of the Russian Federation were proposed to solve the tasks. There are determined main ways of improving the system of nonspecific prevention of parasitic diseases.

scholarly journals ACTUAL PROBLEMS OF ASSESSING THE QUALITY OF DISINFECTION MEASURES FOR PARASITOSIS IN THE RUSSIAN FEDERATION

2020 ◽  
Vol 99 (3) ◽  
pp. 274-278 ◽  
Author(s):  
M. M. Aslanova ◽  
T. V. Gololobova ◽  
K. Yu. Kuznetsova ◽  
A. V. Zagaynova ◽  
Tamari R. Maniya ◽  
...  
Keyword(s):  
Russian Federation ◽  
Professional Community ◽  
Parasitic Infections ◽  
Neglected Diseases ◽  
Parasitic Diseases ◽  
Anthropogenic Pressure ◽  
Difficult Situation ◽  
The Russian Federation ◽  
Parasitic Pathogens

Introduction. The main and the most significant issues of the management of disinfection measures taking into account modern trends and factors affecting the quality of these measures in relation to parasitic infections in the territory of the Russian Federation are considered. The professional community of physicians, epidemiologists, hygienists, disinfectants was almost powerless in the fight against slow or latent infections of a parasitic nature, which are still ca lled “neglected diseases” (“unnoticed diseases”), partly because they occur without pronounced symptoms, and there are a number of unresolved problems in the prevention and diagnosis. Despite the fact that modern medicine in the field of prevention and diagnosis of some infectious diseases has achieved good results, the problems with the disinfection of parasitic pathogens remain relevant. Environmental degradation, various natural disasters, urbanization, increased anthropogenic pressure, as well as climate change do not contribute to improving the difficult situation with regard to the spread, reproduction and formation of new stable foci of parasites. The measures for the improving the system of non-specific prevention of parasitic diseases are determined. Material and methods. In the course of the work, there were analyzed statistical reports of the Federal Reserve and the literature data. Results. The analysis of statistical data showed that during 2014-2018, the incidence of parasites in the Russian population remained at a high level and did not have a pronounced tendency to decrease, and the proposed anti-parasitic disinfectants cannot meet modern anti-epidemiological and hygienic requirements. Conclusion. A number of recommendations and initiatives on disinfection measures for the prevention and spread of parasitic infections in the territory of the Russian Federation were proposed to solve the tasks. There are determined main ways of improving the system of nonspecific prevention of parasitic diseases.

scholarly journals Infestations Myxobolus sp. in Gills Koi (Cyprinus carpio) That No Clinical Symptoms

2020 ◽  
Vol 11 (1) ◽  
pp. 20-25
Author(s):  
Zulkifli ◽  
Novia Christi Prihartini
Keyword(s):  
Water Quality ◽  
Life Cycle ◽  
Clinical Symptoms ◽  
Water Quality Management ◽  
Ornamental Fish ◽  
Parasitic Diseases ◽  
North Sulawesi ◽  
Ornamental Fish Trade ◽  
The Right ◽  
Fish Trade

Ornamental fish trade between regions in Indonesia allows the transfer of disease, especially if the disease does not show clinical symptoms in fish traded. Koi fish in Tahuna, North Sulawesi, mostly come from the area of ​​East Java, which is one area with many cases of myxobolusis. In addition, the potential for parasitic diseases that come along when koi fish are brought between areas cannot be avoided, because the examination of parasites, especially Myxobolus sp. no longer listed in the regulation as a quarantine inspection requirement. The purpose of this study was to see the Myxobolus sp infestation that infected koi in Tahuna, North Sulawesi, although there were no clinical symptoms using conventional techniques and histopathology. The results of the examination showed Myxobolus spore infestation on the gills of the koi, although the amount was not much, both conventional and histopathological techniques. This shows that our level of awareness of the types of parasites that can infect fish is still lacking. Myxobolus sp is only transmitted through the spore stage back and forth; there is no horizontal or vertical transmission in fish or tubifex T worm populations. More knowledge regarding the life cycle of the Myxobolus sp. in order to obtain the right handling to deal with outbreaks, especially water quality management at the location of the cultivation.

Challenges of Hospital Disaster Risk Management: A Systematic Review Study

2021 ◽  
pp. 1-8
Author(s):  
Somayeh Azarmi ◽  
Amir Hosein Pishgooie ◽  
Simintaj Sharififar ◽  
Hamid Reza Khankeh ◽  
Seyyed Ziya Hejrypour
Keyword(s):  
Risk Management ◽  
Thematic Analysis ◽  
The United States ◽  
Disaster Risk ◽  
Study Data ◽  
Disaster Risk Management ◽  
Financial Barriers ◽  
Qualitative Thematic Analysis ◽  
The Status ◽  
Review Study

Abstract Objective: This study aimed to investigate the challenges of hospital disaster risk management so that it can take a step to provide strategies and interventions to remove these barriers and improve the hospital disaster risk management (HDRM) through identifying and introducing them to disaster experts. Methods: This is a systematic qualitative review study. Data sources included Persian and international databases, which were searched using the keywords of hospital, disaster, risk management, risk reduction, disaster and challenge, and the combination of them. The search period ranged from January 2010 to January 2020. Data were extracted by 2 independent examiners for qualitative thematic analysis. Results: A total of 762 articles and documents were recovered. Finally, 12 articles entered the study, including 7 studies from Asia, 2 articles from Europe, 2 articles from the United States, and 1 article about Africa. After thematic analysis, 17 sub-themes were achieved and were classified into 4 subjects of technical-physical barriers, organizational-managerial barriers, financial barriers, and human barriers. All articles have not discussed on all categories. Conclusions: The results of evaluating the challenges of hospital disaster risk management gained from this study can be beneficial in developing a roadmap to improve the status of HDRM.

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