scholarly journals Determination of the activity of fungicides against pathogens of dermatomycoses in domestic animals

2020 ◽  
Vol 22 (99) ◽  
pp. 20-23
Author(s):  
I. M. Kushnir ◽  
V. I. Kushnir ◽  
B. V. Gutyj ◽  
I. S. Semen ◽  
S. D. Murska ◽  
...  
Keyword(s):  
Pathogenic Fungi ◽  
Laboratory Diagnosis ◽  
Domestic Animals ◽  
Chlorhexidine Digluconate ◽  
Microscopic Fungi ◽  
Fusarium Spp ◽  
Candida Spp ◽  
Opportunistic Fungi ◽  
Highly Active ◽  
Malassezia Spp

The aim of the study was to identify and identify the causative agents of dermatomycosis in dogs and cats and to determine their sensitivity to solutions of ketonazole and chlorhexidine digluconate, which are part of the drug Skinhard. This is a spray for external use, manufactured by PJSC “Halychpharm”. For laboratory diagnosis of dermatomycoses, samples from the affected parts of the skin and fur of domestic animals were used. To isolate a pure culture of fungi were sown on selective media: wort agar, agar Saburo, Chapek. The optimal cultivation regime for pathogenic fungi was 20–25 °С. Isolated fungal cultures were identified by the appearance and shape of colonies, their consistency, color, ability to grow at 37 °C, microscopic structure, in particular - the nature of mycelial branching and the presence of septa, location of conidiophores, spores and other signs. A microbiological examination of the affected areas of the skin of dogs and cats was performed to detect microscopic fungi. The following fungi were isolated from dogs affected by mycoses: Candida spp., Aspergillus niger, Epidermophyton spp., Microsporum spp., Mucor spp., Trichophyton spp., Mallasseria spp., Sporotrich spp, Candida albicans, and from cats: Microspor Candida spp., Spototrich spp., Rhizorus spp., Fusarium spp. Trichophyton spp. Isolated microscopic fungi of the genus Malassezia spp. belong to superficial mycoses (keratomycoses) and affect the superficial layers of skin and hair. Epidermatophytes: Trichophyton spp., Epidermophyton spp., Microsporum spp. affect the epidermis, skin and coat. In addition, opportunistic fungi of the genus Aspergillus spp, Mucor spp., Rhizorus spp. and Fusarium spp. Chlorhexidine digluconate was found to be highly active against dermatophytes (Trichophyton spp., Microsporum spp.), Less active against fungi of the genus Candida and less active against Aspergillus spp, Mucor spp., Rhizorus spp, Fusarium spp. Ketonazole is highly active against dermatophytes (Trichophyton spp., Epidermophyton spp., Microsporum spp.), Yeast (Malassezia spp., Candida spp.,) And opportunistic fungi (Aspergillus spp., Mucor spp., Rhizorus spp.).

scholarly journals SPECIES COMPOSITION OF CANDIDA SPP. ISOLATED FROM DIFFERENT SOURCES AND THEIR SENSITIVITY TO ANTIFUNGAL PREPARATIONS

2018 ◽  
Vol 97 (3) ◽  
pp. 204-207
Author(s):  
Yana N. Frolova ◽  
M. A. Morozova ◽  
I. V. Didenko
Keyword(s):  
Pathogenic Fungi ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Microscopic Fungi ◽  
Disc Diffusion Method ◽  
Candida Spp ◽  
Adequate Treatment ◽  
Specific Composition ◽  
Different Sources

About 100,000 species of microscopic fungi were currently identified. Data on diseases caused by conditionally pathogenic fungi is particularly noteworthy. Both specific composition of Candida spp. found at fish-rearing farms of Rostov and Krasnodar regions and their susceptibility to antibiotics preparations have been studied. Strain susceptibility to drugs was determined by the disc-diffusion method. Significant variations are observed in the Candida resistance to four antibiotic preparations. Some sturgeon fingerlings and breeders have been found to be infected with candida. The drugs from the group of polyenes showed the greatest activity against the studied crops Candide. Despite the susceptibility of C. glabrata, C. guillermondii, C. tropicalis C. albicans to nystatin, the application of reabsorbing antifungals (in vivo) candidiasis of the intestine fails to be efficient. The data obtained show antibiogram to be expedient when assigning an adequate treatment of candidosis.

scholarly journals The Detection of Pathogenic Fungi on Prayer Rugs of The Mosques at Jatinangor Campus of Universitas Padjadjaran

2019 ◽  
Vol 2 (3) ◽  
Author(s):  
Faturrachman Faturrachman ◽  
Yanti Mulyana
Keyword(s):  
Fungal Growth ◽  
Pathogenic Fungi ◽  
Simple Random Sampling ◽  
Fungal Species ◽  
Moist Air ◽  
Candida Spp ◽  
Opportunistic Fungi ◽  
Plateau Area ◽  
Penicillium Spp ◽  
Descriptive Method

Fungus easily grows in the plateau area with warm moist air. The fungus can enter and contaminate mosque rooms, especially on the surface of prayer rugs. If pathogenic fungi grow on prayer rugs, they can increase the health risk of those who come into contact with them. This research aimed to detect and identify pathogenic fungi on prayer rugs of the mosques in Jatinangor campus of Universitas Padjadjaran using laboratoric descriptive method. The data was collected by sampling of dust from the surface of prayer rugs, fungal culturing and mold identification. The existence of pathogenic fungi has been investigated and observed in twenty-eight samples of thirty mosques using simple random sampling. Sabouraud Dextrose Agar was the chosen medium to grow pathogenic fungi. We found fungal growth in all samples with a total of 8 fungal species (Alternaria spp, Aspergillus spp, Candida spp, Fonsecaea spp, Mucor spp, Penicillium spp, Rhizopus spp, Rhodotorula spp) which are opportunistic fungi; however, no pathogenic fungi were found.Keywords : pathogenic fungi, prayer rugs, fungus, Aspergillus spp., Candida spp.

scholarly journals Ibrexafungerp: A First-in-Class Oral Triterpenoid Glucan Synthase Inhibitor

2021 ◽  
Vol 7 (3) ◽  
pp. 163 ◽  
Author(s):  
Sabelle Jallow ◽  
Nelesh P. Govender
Keyword(s):  
Pathogenic Fungi ◽  
Candida Spp ◽  
Fungal Cell ◽  
Favourable Safety ◽  
Favourable Safety Profile ◽  
Synthase Inhibitor ◽  
Increased Activity ◽  
In Vitro Data

Ibrexafungerp (formerly SCY-078 or MK-3118) is a first-in-class triterpenoid antifungal or “fungerp” that inhibits biosynthesis of β-(1,3)-D-glucan in the fungal cell wall, a mechanism of action similar to that of echinocandins. Distinguishing characteristics of ibrexafungerp include oral bioavailability, a favourable safety profile, few drug–drug interactions, good tissue penetration, increased activity at low pH and activity against multi-drug resistant isolates including C. auris and C. glabrata. In vitro data has demonstrated broad and potent activity against Candida and Aspergillus species. Importantly, ibrexafungerp also has potent activity against azole-resistant isolates, including biofilm-forming Candida spp., and echinocandin-resistant isolates. It also has activity against the asci form of Pneumocystis spp., and other pathogenic fungi including some non-Candida yeasts and non-Aspergillus moulds. In vivo data have shown IBX to be effective for treatment of candidiasis and aspergillosis. Ibrexafungerp is effective for the treatment of acute vulvovaginal candidiasis in completed phase 3 clinical trials.

Mycotic infections in animals in India: An update

2021 ◽  
Vol 1 ◽  
pp. 12
Author(s):  
Harish Chander Gugnani
Keyword(s):  
Literature Search ◽  
West Bengal ◽  
Pathogenic Fungi ◽  
Domestic Animals ◽  
Microsporum Canis ◽  
Geophilic Dermatophyte ◽  
Trichophyton Simii ◽  
Zoophilic Dermatophytes ◽  
Mycotic Infections ◽  
Demographic Features

This review traces the early records of mycotic infections in India, and presents an update of animal mycoses reported from several parts of India. The types of mycoses covered are the dermatophytosis (ringworm) in domestic animals due to well-known species of zoophilic dermatophytes, viz. Trichophyton simii, T. mentagrophytes, T. verrucosum, Microsporum canis and M. nanum, and the geophilic dermatophyte, M. gypseum, Aspergillus spp, Cryptococcus species and other yeast like fungi, histoplasma and blastomyces. The brief clinical and demographic features of infections in different animals are described. A particularly noteworthy finding in literature search is the report of clinical infections in one dog and two cows by an anthropophilic dermatophyte, T. rubrum from Belgachia, Kolkata, West Bengal in 1954. Veterinary scientists are urged to investigate the possible occurrence of infections in animals due to other pathogenic fungi including the dimorphic ones like Histoplasma and Blastomyces.

scholarly journals Evaluation of pathogenic fungi occurrence in traumatogenic structures of freshwater fish

2011 ◽  
Vol 44 (2) ◽  
pp. 182-185 ◽  
Author(s):  
Fabio Caetano Oliveira Leme ◽  
Marcos Mendes de Barros Negreiros ◽  
Fernando Akira Koga ◽  
Sandra de Moraes Gimenes Bosco ◽  
Eduardo Bagagli ◽  
...  
Keyword(s):  
Freshwater Fish ◽  
Fungal Infections ◽  
Pathogenic Fungi ◽  
Dematiaceous Fungi ◽  
Candida Spp ◽  
Pathogenic Potential ◽  
Infection Route ◽  
5.8S Rdna ◽  
Dorsal Fin ◽  
Pimelodus Maculatus

INTRODUCTION: Fungal infections in human skin, such as sporotrichosis, can occur after fish induced trauma. This work aimed to identify fungi in freshwater fish that are pathogenic to humans. METHODS: Extraction of dental arches from Serrassalmus maculatus (piranha) and Hoplias malabaricus (wolf fish), stings from Pimelodus maculatus (mandis catfish), dorsal fin rays from Plagioscion spp. (corvina) and Tilapia spp., for culture in Mycosel agar. Some cultures were submitted to DNA extraction for molecular identification by sequencing ITS-5.8S rDNA. RESULTS: Cultures identified most yeast as Candida spp., while sequencing also permitted the identification of Phoma spp. and Yarrowia lipolytica. CONCLUSIONS: While the search for S. schenckii was negative, the presence of fungus of the genera Phoma and Candida revealed the pathogenic potential of this infection route. The genus Phoma is involved in certain forms of phaeohyphomycosis, a subcutaneous mycosis caused by dematiaceous fungi, with reports of infections in human organs and systems. Traumatizing structures of some freshwater fish present pathogenic fungi and this may be an important infection route that must be considered in some regions of Brazil, since there are a large number of a fisherman in constant contact with traumatogenic fish.

scholarly journals Micoses superficiais na cidade de Manaus, AM, entre março e novembro/2003

2006 ◽  
Vol 81 (3) ◽  
pp. 238-243 ◽  
Author(s):  
José Augusto Almendros de Oliveira ◽  
Jacqueline de Aguiar Barros ◽  
Ana Cláudia Alves Cortez ◽  
Juliana Sarmento Rocha Leal de Oliveira
Keyword(s):  
Tinea Capitis ◽  
Candida Spp ◽  
Malassezia Spp

FUNDAMENTOS: Micoses superficiais estritas são infecções fúngicas que se localizam nas camadas superficiais da pele e seus anexos. As micoses superficiais cutâneas representadas pelas dermatofitoses e candidíases podem ultrapassar a camada córnea da pele. Na região amazônica possuem incidência elevada. OBJETIVOS: Estudar as micoses superficiais, estritas e cutâneas, diagnosticadas sob o ponto de vista epidemiológico e micológico. PACIENTES E MÉTODOS: Pacientes com suspeita clínica de micoses superficiais submetidos a exame micológico no período de março a novembro de 2003 no Laboratório de Micologia Médica/CPCS/INPA. RESULTADOS: Foram realizados 394 exames, tendo 256 apresentado diagnóstico positivo. As micoses mais incidentes foram onicomicoses (135) e pitiríase versicolor (98). Malassezia spp. (77) e Candida spp. (72) foram os agentes fúngicos mais isolados. Tinea capitis apresentou maior ocorrência nos pré-escolares (3), e onicomicoses em adultos (94). O sexo feminino foi o mais acometido (91). Todas as classes sociais foram infectadas, com predominância da C (37). CONCLUSÃO: Onicomicoses e pitiríase versicolor acometeram sobretudo adultos. A Tinea capitis ocorre principalmente, em crianças. As micoses superficiais apresentaram mais incidentes nas mulheres. Malassezia spp. e Candida spp. foram os agentes mais isolados.

scholarly journals Effect of fungal incidence on physiological quality of tobacco seeds used in Brazil

2018 ◽  
Vol 85 (0) ◽  
Author(s):  
Mariane Sayuri Ishizuka ◽  
Maria Heloisa Duarte de Moraes ◽  
Maria Helena Carmignani Pescarin Chamma ◽  
Carlos Eduardo Pulcinelli ◽  
José Otavio Machado Menten
Keyword(s):  
Seed Treatment ◽  
Pathogenic Fungi ◽  
Test Results ◽  
Fusarium Spp ◽  
Germination Test ◽  
Tobacco Seed ◽  
Tobacco Seeds ◽  
Physiological Quality ◽  
Seeds Germination

ABSTRACT: The objectives of the present project were to evaluate the sanity and germination of tobacco seed samples cultivated in Brazil and to identify potential pathogenic fungi to the culture. Thirty-four representatives samples of tobacco seeds were evaluated through germination and sanity test by the blotter-test. On the germination test, results were expressed in percentage of seedlings considered normal, abnormal and non-germinated seeds. The percentage of seeds germination varied between 54.5 and 90%. According to sanity test, it was verified the incidence of Alternaria alternata, Cladosporium spp., Fusarium spp., and Phoma spp. The incidence of A. alternata varied from 3 to 67%, and Fusarium spp. varied from 0 to 19%. There was significative positive correlation between the incidence of A. alternata and the percentage of seed germination. Species of Alternaria and Fusarium can be potential pathogens to tobacco culture and an alarm for the necessity of seed treatment of the seeds that are transporting these fungi.

Bacterial and Fungal Keratitis: A Retrospective Analysis at a University Hospital in Switzerland

2019 ◽  
Vol 236 (04) ◽  
pp. 358-365 ◽  
Author(s):  
Alexandra Bograd ◽  
Theo Seiler ◽  
Sara Droz ◽  
Stefan Zimmerli ◽  
Beatrice Früh ◽  
...  
Keyword(s):  
Contact Lenses ◽  
Topical Therapy ◽  
Fungal Growth ◽  
Fungal Keratitis ◽  
University Hospital ◽  
Fusarium Spp ◽  
Candida Spp ◽  
Coagulase Negative Staphylococci ◽  
History Of ◽  
Time Periods

Abstract Background Infectious keratitis is a serious corneal disease and may lead to permanent visual deterioration if not treated rapidly and effectively. In order to determine possible changes in the spectrum of pathogens over time, we evaluated the pathogenic organisms of keratitis at a university hospital in Switzerland, comparing two time periods within a decade. Methods In this retrospective study, 417 patients with the clinical diagnosis of bacterial or fungal keratitis in 2006/07 and 2015/16 were enrolled. In an additional analysis, all cases of fungal keratitis between 2006 and 2016 were evaluated. Collected parameters were age, gender, side, use of contact lenses, systemic, neurological and ocular diseases, trauma, previous surgery, and systemic and topical therapy before presentation. In each patient, microbiological results of corneal smears such as growth and antibiotic resistance were analysed. Results A total of 163 and 254 eyes were included in 2006/07 and 2015/16, respectively. In 2006/07, a culture of smears revealed a bacterial cause in 70 eyes (42.9%) and a fungal cause in 4 eyes (2.5%), whereas in 2015/16, bacterial growth was found in 115 eyes (45.3%) and fungal growth in 6 eyes (2.4%). The most common bacteria in 2006/07 and 2015/16 were coagulase-negative Staphylococci (44.3 vs. 49.6%), Pseudomonas aeruginosa (18.6 vs. 13.9%), Staphylococcus aureus (10 vs. 16.5%), Corynebacterium spp. (8.6 vs. 5.2%), and Moraxella spp. (7.1 vs. 9.6%). Candida parapsilosis was the most common fungal isolate in both groups (25 vs. 33.3%). Between 2006 and 2016, fungal keratitis was found in 37 eyes (Candida spp. n = 11, Fusarium spp. n = 11, Aspergillus spp. n = 5, others n = 10). All patients with Fusarium spp. keratitis had a history of wearing contact lenses. Conclusion The most commonly isolated bacterial organisms were Staphylococci and Pseudomonas spp., whereas fungal keratitis was mainly due to Candida spp. or Fusarium spp. No relevant variation in causative pathogens was observed between the two time periods.

scholarly journals Communities of bacteria and fungi occurring in the rhizosphere of winter wheat

2017 ◽  
Vol 38 (SI 2 - 6th Conf EFPP 2002) ◽  
pp. 361-363
Author(s):  
E. Patkowska ◽  
D. Pięta ◽  
A. Pastucha
Keyword(s):  
Species Composition ◽  
Winter Wheat ◽  
Pathogenic Fungi ◽  
Microbiological Analysis ◽  
Qualitative Composition ◽  
Fusarium Spp ◽  
Wheat Rhizosphere ◽  
Bacillus Spp ◽  
Bacteria And Fungi ◽  
Total Bacteria

The purpose of the present studies was to establish the species composition of fungi occurring on the underground parts of winter wheat, Kobra cv. and to determine the quantitative and qualitative composition of microorganisms developing in the rhizosphere of this plant. The mycological analysis of the infected roots and the stem base of winter wheat gave 320 fungi isolates. Fusarium spp. were most frequently isolated, and their proportion was 64.7% of all the fungi. This genus was represented by F. avenaceum, F. culmorum, F. equiseti, F. graminearum, F. oxysporum and F. solani. Among these species the dominating ones were F. avenaceum (19.4%) and F. culmorum (38.7%). The microbiological analysis of winter wheat rhizosphere gave the highest number of total bacteria (6.32 × 106 cfu/g of d.w. of soil). The number of Pseudomonas pp. was 3.56 × 106 cfu/g of d.w. of soil, and the number of Bacillus spp. was 2.42 × 106 cfu/g of d.w. of soil. Fusarium spp. and Rhizoctonia solani dominated within pathogenic fungi isolated from the rhizosphere of winter wheat.

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