scholarly journals Diyabette Kullanılan Bitkisel Desteklerin Etkinliği ve Güvenilirliği

2019 ◽  
Vol 47 ◽  
pp. 110-117
Author(s):  
Ezgi Bellikci Koyu

Bitkiler uzun yüzyıllar boyunca tedavinin en önemli parçası olmuşlardır. On dokuzuncu yüzyılda kimya alanında önemli gelişmelerin olması ve ilaç moleküllerinin keşfi ile bitkilerin tıbbi amaçlı kullanımları giderek azalsa da, son yıllarda doğaya dönüş çabaları içerisinde kullanımlarında yeniden bir artış gözlenmektedir. Özellikle diyabet gibi kronik seyirli hastalıklarda modern tedaviye destek olarak bu ürünlerin kullanımları sıklıkla tercih edilmektedir. Bu ilgiye paralel olarak son yıllarda bitkilerin diyabet tedavisindeki etkisini araştıran klinik çalışmalar da artmaya başlamıştır. Etkinliğin yanı sıra bitkilerin güvenilir kullanımları da son derece önemlidir. Doğru bitkinin kullanımı, kullanılan ürünün bileşimi, kalitesi, hazırlama yöntemi, yan etkileri, ilaç etkileşimleri ve kontraendikasyonları da tedavi sürecini etkileyen ve güvenilir kullanım için göz önünde bulundurulması gereken faktörlerdir. Bu derlemede tarçın (Cinnamomum sp.), çörek otu (Nigella sativa L.), kudret narı (Momordica charantia L.), çemen otu (Trigonella foenum-graecum L.), zencefil (Zingiber officinale Roscoe) ve ısırgan otu (Urtica dioica L.) gibi diyabet tedavisinde sıklıkla tercih edilen bitkilerin etkinliği ve güvenilirliği değerlendirilmiştir.

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1566
Author(s):  
Sylwia Ewa Pałka ◽  
Agnieszka Otwinowska-Mindur ◽  
Łukasz Migdał ◽  
Michał Kmiecik ◽  
Dorota Wojtysiak

The purpose of the study was to analyse the effect of nettle (Urtica dioica L.) leaves and fenugreek (Trigonella foenum-graecum L.) seeds as additives to fodder in order to improve post-slaughter traits and quality parameters of Termond White rabbit meat (n = 60; 30 , 30 ). Three experimental groups were created. The control group (n = 20; 10 and 10 ) was fed ad libitum feed containing corn, bran, wheat, dried alfalfa, soybean meal, sunflower meal, dicalcium phosphate, calcium carbonate and vitamin-mineral premix. The animals from the first experimental group (n = 20; 10 and 10 ) were fed a complete mixture added with 1% of nettle (Urtica dioica L.) leaves. Rabbits from the second group (n = 20; 10 and 10 ) were fed with a complete mixture added with 1% of fenugreek (Trigonella foenum-graecum L.) seeds. Rabbits fed with pellets with the addition of nettle were characterized by a higher slaughter weight, higher weight of hot and cold carcasses, lungs, kidneys and head as well as a higher weight of the fore, middle and hind part of the carcass compared to the other two groups. The carcasses of animals fed with fenugreek and nettle had a higher percentage of the fore and hind parts compared to the carcasses of the animals from the control group. The female carcasses were characterized by a significantly higher percentage of the middle part compared to the male carcasses. For most colour measurement traits, the differences depending on the feeding regime were significant. The effect of gender on meat colour was non significant. The effect of feeding regime and of gender on texture traits such as shear force, hardness, springiness, cohesiveness and chewiness were non significant. Feeding had no effect on muscle fibre diameter, but it affected the muscle fibre type I percentage. Thus, the group fed with pellets containing nettle leaves had higher percentage of type I muscle fibres than the control group. The effect of gender on muscle fibre traits was non significant.


2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Sleman Kadan ◽  
Bashar Saad ◽  
Yoel Sasson ◽  
Hilal Zaid

Despite the enormous achievements in conventional medicine, herbal-based medicines are still a common practice for the treatment of diabetes.Trigonella foenum-graecum,Atriplex halimus,Olea europaea,Urtica dioica,Allium sativum,Allium cepa,Nigella sativa, andCinnamomum cassiaare strongly recommended in the Greco-Arab and Islamic medicine for the treatment and prevention of diabetes. Cytotoxicity (MTT and LDH assays) of the plant extracts was assessed using cells from the liver hepatocellular carcinoma cell line (HepG2) and cells from the rat L6 muscle cell line. The effects of the plant extracts (50% ethanol in water) on glucose transporter-4 (GLUT4) translocation to the plasma membrane was tested in an ELISA test on L6-GLUT4myc cells. Results obtained indicate thatCinnamomon cassiais cytotoxic at concentrations higher than 100 μg/mL, whereas all other tested extracts exhibited cytotoxic effects at concentrations higher than 500 μg/mL. Exposing L6-GLUT4myc muscle cell to extracts fromTrigonella foenum-graecum,Urtica dioica,Atriplex halimus, andCinnamomum verumled to a significant gain in GLUT4 on their plasma membranes at noncytotoxic concentrations as measured with MTT assay and the LDH leakage assay. These findings indicate that the observed anti-diabetic properties of these plants are mediated, at least partially, through regulating GLUT4 translocation.


2021 ◽  
pp. 2000269
Author(s):  
Esmaeil Rezaei‐Chiyaneh ◽  
Martin Leonardo Battaglia ◽  
Amir Sadeghpour ◽  
Fahime Shokrani ◽  
Adel Dabbagh Mohammadi Nasab ◽  
...  

2012 ◽  
Vol 7 (2) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Michał Tomczyk ◽  
Marijana Zovko-Končić ◽  
Lech Chrostek

Alcoholism is a medical, social, and economic problem where treatment methods mostly include difficult and long-lasting psychotherapy and, in some cases, quite controversial pharmacological approaches. A number of medicinal plants and pure natural compounds are reported to have preventive and therapeutic effects on alcoholism and alcohol dependency, but their constituents, efficacy and mechanism of action are mostly unknown so far. Recently, kudzu [ Pueraria lobata (Willd.) Ohwi], St. John's wort ( Hypericum perforatum L.), danshen ( Salvia miltiorrhiza Bge.), ginseng ( Panax ginseng C.A. Mey.), Japanese raisin tree ( Hovenia dulcis Thunb.), ibogaine ( Tabernanthe iboga H. Bn.), evening primrose ( Oenothera biennis L.), prickly pear fruit ( Opuntia ficus indica (L.) Mill.), purple passionflower ( Passiflora incarnata L.), thyme ( Thymus vulgaris L.), fenugreek seed ( Trigonella foenum-graecum L.), ginger ( Zingiber officinale Roscoe) and many others drew the attention of researchers. Can, therefore, drugs of natural origin be helpful in the treatment of alcoholism or in decreasing alcohol consumption?


2020 ◽  
Vol 10 (2) ◽  
pp. 167-173
Author(s):  
Musyirna Rahmah Nasution ◽  
Syamira

Herbal tea is a formulation of herbal flowers, seeds, leaves, roots, and bark of various plants. It has affectiveness in energizing, healing constipation and approving immune. It has been done an experiment of antioxidant activity of herbal tea from the mixture of bitter melon (Momordica charantia L), red ginger (Zingiber officinale Roscoe) and curcuma (Curcuma xanthorrhiza Roxb). The purpose of this experiment is to make formulation of herbal tea that has strong antioxidant activity and preferably from a mixture of bitter melon (Momordica charantia L), red ginger (Zingiber officinale Roscoe) and curcuma  (Curcuma xanthorrhiza Roxb) that has been dried at a temperature of 50-60°C.The activity of antioxidant is measured by DPPH method, meanwhile organoleptic is analyzed by hedonic method. The result of the experiment from 4 formulations indicates that high antioxidant activity is FIII based on analysis one way ANOVA and Tukey test 99% true. The compositions of FIII are 1,25 g bitter melon, 0,375 g red ginger and 0,375 g curcuma has high antioxidant in 97,25%. Hedonic test indicates FIII in liking category after added 2 g palm sugar and 5mL lemon.  


2020 ◽  
Vol 16 (4, Accepted for print) ◽  
pp. 31-36
Author(s):  
Sylwia Pałka ◽  
Michał Kmiecik ◽  
Łukasz Migdał

<b>The purpose of the experiment was to investigate the effect of the addition of nettle (<i>Urtica dioica</i> L.) leaves or fenugreek (<i>Trigonella foenum-graecum</i> L.) seeds to rabbit feed on their breeding and lactation performance. The research material was female Blanc de Termonde rabbits (n = 22) and their offspring – four consecutive litters. The does were divided into three feeding groups, and each group was fed <i>ad libitum</i> a commercial pelleted complete feed with min. 17,5% crude protein, max. 15% crude fibre, and 2-3% crude fat. The diet for does in the control group (n = 6) contained wheat bran, dried alfalfa, extracted soybeans, barley, beet pulp, sunflower meal, and a vitamin and mineral supplement. The does in experimental group I (n = 8) were fed a diet enriched with 2% dried nettle leaves, while the diet for experimental group II (n = 8) contained fenugreek seeds (2%). The rabbits were mated between 10 and 14 days after kindling. To examine the effect of the herbal supplements on the does’ reproductive and lactation performance, the following information was collected: number of rabbits born per litter, litter weight at 24 h after birth and at 21 days of age, and milk yield. Statistical analysis was performed using the SAS statistical package. The results show positive effects of the use of nettle leaves and fenugreek seeds in the diet of female rabbits, but this should be confirmed in further research.</b>


2013 ◽  
Vol 49 (3) ◽  
pp. 413-422 ◽  
Author(s):  
Ahmad Ghorbani

Diabetes mellitus is a public health problem which leads to serious complications over time. Experimentally, many herbs have been recommended for treating diabetes. In most cases, however, the recommendations are based on animal studies and limited pieces of evidence exist about their clinical usefulness. This review focused on the herbs, the hypoglycemic actions of which have been supported by three or more clinical studies. The search was done in Google Scholar, Medline and Science Direct databases using the key terms diabetes, plants, herbs, glucose and patients. According to the clinical studies, Aegle marmelos, Allium cepa, Gymnema sylvestre, Momordica charantia, Ocimum sanctum, Nigella sativa, Ocimum sanctum, Panax quinquefolius, Salacia reticulate, Silybum marianum and Trigonella foenum-graecum have shown hypoglycemic and, in some cases, hypolipidemic activities in diabetic patients. Among them, Gymnema sylvestre, Momordica charantia, Silybum marianum and Trigonella foenum-graecum have acquired enough reputation for managing diabetes. Thus, it seems that physicians can rely on these herbs and advise for the patients to improve management of diabetes.


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