scholarly journals Total Score Differences of Hospital Anxiety and Depression Scale – Depression (HADS-D) in Patients with Multidrug-Resistant Tuberculosis (MDR-TB) Based on Gender at H. Adam Malik General Hospital Medan

2021 ◽  
Vol 4 (1) ◽  
pp. 1461-1466
Author(s):  
M. Surya Husada ◽  
Bahagia Loebis ◽  
Ariwan Selian
Keyword(s):  
General Hospital ◽  
Psychiatric Morbidity ◽  
Depression Scale ◽  
Multidrug Resistant ◽  
Anxiety And Depression ◽  
P Value ◽  
Hospital Anxiety ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb

Tuberculosis (TB) is a contagious and airborne disease. Over the decades, psychiatric morbidity in patients with MDR-TB has become increasingly recognized. Resistant tuberculosis is currently a serious health problem worldwide. This chronic disease takes a long time and causes various side effects, often causing symptoms of depression and anxiety in patients with Multidrug-resistant tuberculosis (MDR-TB) and pulmonary tuberculosis (TB). However, there are still relatively few who focus on psychiatric disorders in patients with MDR-TB. To find out the total score differences of Hospital Anxiety and Depression Scale - Depression (HADS-D) in patients with Multidrug-Resistant Tuberculosis (MDR-TB) based on gender. This study is an Unpaired Two Group Numerical Comparative Analytical study with a cross-sectional approach, namely by describing and analyzing a situation at a certain time using the Hospital Anxiety and Depression Scale - Depression (HADS-D) instrument. The results of the analysis with the Pearson test obtained a p-value <0.001 (p <0.05). There is a difference in the total score of Hospital Anxiety and Depression Scale - Depression (HADS-D) in patients with Multidrug-resistant tuberculosis (MDR-TB) based on gender at the H. Adam Malik General Hospital Medan.

scholarly journals KAMI-PMO TB (EDUKASI DAN PENDAMPINGAN PENGAWAS MENELAN OBAT TB) DALAM PENGENDALIAN MDR TB

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Mareta Dea Rosaline ◽  
Santi Herlina
Keyword(s):  
Multidrug Resistant ◽  
T Test ◽  
P Value ◽  
Test Analysis ◽  
Pulmonary Tb ◽  
Drug Ingestion ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb ◽  
Paired T Test

Tuberculosis control in Indonesia is still not optimal. The problem of MDR TB (Multidrug-Resistant Tuberculosis) is an obstacle to controlling TB in Indonesia. MDR TB is caused by no response from TB germs to treatment isoniazid and rifampicin, anti-tuberculosis drugs. TB incidence rate in Serang district ranks second in Banten Province after Tangerang. The number of pulmonary TB cases is due to the lack of public knowledge and awareness about pulmonary TB disease. To reduce the adverse effects of MDR TB requires the involvement of cadres or family members who controlling drug ingestion (PMO). The form of activities carried out through the formation of cadres to care for TB through the KAMI-PMO TB (Education and Assistance for TB Medication Supervisors) in Desa Baros, Kabupaten Serang. The purpose is to increase the commitment, ability, and knowledge of cadres as coordinator of PMO (Drug Swallow Supervisor) to control MDR TB. The method of implementing activities is counseling, demonstrations, and assistance to cadres. The media used were PPT, WE-PMO TB Booklet, and educational videos. The result of the training was an increase in the ability of cadres in providing PMO counseling by 87%. The Paired T-Test analysis results showed a p-value of 0.000, which means that the training conducted affected cadres' knowledge of PMO TB. In conclusion, education and assistance to cadres have a good influence in increasing knowledge and abilities. The expected result is TB care cadres can provide aid and become the coordinator of TB PMO (Drug Ingestion Supervisor).  ABSTRAK:Pengendalian Tuberculosi di Indonesia masih belum optimal.Permasalahan MDR TB (Multidrug Resistant Tuberculosis) merupakan hambatan pengendalian TB di Indonesia. MDR TB disebabkan tidak ada respon kuman TB terhadap pengobatan isoniazid dan rifampizin yang merupakan obat anti tuberculosis. Angka kejadian TB di kabupaten Serang menempati urutan kedua di Provinsi Banten setelah Tangerang, dan banyaknya kasus TB Paru dikarenakan pengetahuan dan kesadaran masyarakat tentang penyakit TB Paru masih kurang. Untuk mengurangi dampak buruk MDR TB dibutuhkan keterlibatan peran serta kader peduli TB atau anggota keluarga yang berperan dalam pengawasan menelan obat (PMO). Bentuk kegiatan yang dilakukan sebagai bentuk pemberdayaan masyarakat melalui pembentukan kader peduli TB  melalui KAMI-PMO TB (Edukasi dan Pendampinga Pengawas Menelan Obat TB) di Desa Baros Kabupaten Serang. Tujuan dari pengabdian masyarakat adalah meningkatkan komitmen, kemampuan dan pengetahuan kader sebagai koordinator PMO (Pengawas Menelan Obat) dalam upaya pengendalian MDR TB. Metode pelaksanaan kegiatan adalah penyuluhan, demontrasi, dan pendampingan kader. Media yang digunakan yaitu PPT, Booklet KAMI-PMO TB , dan video edukasi. Hasil dari kegiatan adalah meningkatnya kemampuan kader dalam memberikan penyuluhan PMO cukup tinggi sebesar 87%. Hasil analisis uji Paired T- Test didapatkan nilai p value 0,000 yang artinya ada pengaruh pelatihan yang dilakukan terhadap pengetahuan kader tentang PMO TB. Kesimpulannya edukasi dan pendampingan kepada kader memiliki pengaruh yang baik  dalam meningkatkan pengetahuan dan kemampuan, sehingga hasil yang diharapkan kader peduli TB dapat melakukan pendampingan pada pasien TB dan menjadi koordinator PMO (Pengawas Menelan Obat) TB dalam upaya pengendalian MDR TB

scholarly journals Health education on multidrug-resistant tuberculosis prevention among tuberculosis patients

2021 ◽  
Vol 10 (1) ◽  
pp. 27
Author(s):  
Hema Malini ◽  
Emil Huriani ◽  
Devia Putri Lenggogeni ◽  
Shinta Herlina
Keyword(s):  
Health Education ◽  
Community Health Centers ◽  
Statistical Tests ◽  
Group Discussion ◽  
Sampling Technique ◽  
Multidrug Resistant ◽  
P Value ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb

The high incidence of multidrug-resistant tuberculosis (MDR-TB) in the community due to the lack of socialization or the provision of health education about MDR-TB. During this time, health education is only focused on tuberculosis (TB) generally. The purpose of this study was to determine the effect of health education on the behavior of MDR-TB prevention in patients with pulmonary tuberculosis in two Community Health Centers in Padang. This study design is quasi-experimental with pre and post-test groups only. The program intervention of health education was conducted for a month with lecture method and group discussion using flipchart and video as media. The sampling technique used purposive sampling were 29 patients with TB who are still in the phase of treatment. Data collection used a set of questionnaires. The data analysis in this study using statistical tests t-test. The results showed, there is a significance influence of health education on knowledge with p-value=0.000 (p≤0.05) and attitude with p-value=0.000 (p≤0.05). The result also showed that 65.5% of patients taking medication regularly. It was also that there is the effect of health education on the behavior of MDR-TB prevention in TB patients. It is expected that the providing of health education on the prevention of behavior on MDR-TB is emphasized on the motivation and self-efficacy of the patients and involvement of supervision on taking medication.

scholarly journals The Relationship between Previous Tuberculosis Treatment and HIV Status with Multidrug-Resistant Tuberculosis

2019 ◽  
Vol 14 (3) ◽  
pp. 347-352
Author(s):  
Dyan Kunthi Nugrahaeni ◽  
Salma Zaqiya
Keyword(s):  
Multidrug Resistant ◽  
Dominant Factor ◽  
P Value ◽  
Hiv Status ◽  
Tb Treatment ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb ◽  
History Of ◽  
The Relationship

Multidrug-resistant tuberculosis (MDR-TB) is becoming major public health issues in the world. Among the causes are history of previous TB treatment and increased co-infection of TB-HIV (Human Immunodeficiency Virus). This study aimed to identify the relationship between history of previous TB treatment and HIV status with MDR-TB. This is a case control study. The sample case was patients with MDR-TB, while sample control was patient who have drug-sensitive TB. Secondary data was obtained from patient medical records and laboratory results at Rotinsulu Pulmonary Hospital Bandung. Data were analyzed using chi-square. Multiple logistic regression was used to identify the dominant factor that influence the occurrence of MDR-TB. This study showed that the history of previous TB treatment was statistically significant with MDR-TB (p value= 0.001; OR= 18.889; 95% CI= 4.093-87.172) and it is the dominant factor that influence MDR-TB (p value= 0.0001; OR= 56.84; 95% CI= 6.9- 468.87). HIV infection at control group (who contracted drug-sensitive TB) was 26.1% (p value= 0.022). This finding suggested that HIV testing should be performed to each TB and MDR-TB patients and increased collaboration TB-HIV program between the other health care facilities should ensue. Drug sensitivity testing should be conducted at the start of TB treatment for patients with previous TB treatment and TB-HIV co-infection.

scholarly journals Epidemiology of Drug Resistant Tuberculosis in Samtse General Hospital, Bhutan: A Retrospective Study

2019 ◽  
Vol 17 (1) ◽  
pp. 41-46
Author(s):  
Thinley Dorji
Keyword(s):  
General Hospital ◽  
Multidrug Resistant ◽  
Cross Sectional Study ◽  
Drug Resistant ◽  
Cross Sectional ◽  
Tb Treatment ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
High Prevalence ◽  
Mdr Tb

Introduction: Multidrug resistant tuberculosis (MDR-TB) is defined as a case of tuberculosis resistant to rifampicin and isoniazid which are the first line anti tuberculosis drugs. Globally emergences of MDR-TB possess a challenge to TB control. In Bhutan, the proportion of MDR-TB is high at par with the global level. This study will explore the predictors of MDR-TB and the trend at Samtse General Hospital which has high burden of tuberculosis. Methods: This was a retrospective cross sectional study. The data was extracted from TB treatment cards maintained at TB unit of Samtse General Hospital TB from January 2012 to June 2018. Results: The study showed the prevalence of drug resistant to at least one drug at 21% and MDR-TB prevalence at 16%. The patients with previous treatments (AOR: 4.59; 95% CI .03-.18) and patients under the age of 30 years (AOR: 2.7; 95% CI 1.01- 7.42) were significantly associated with MDR-TB. Conclusion: This study shows high prevalence of MDR-TB in Samtse. Better strategies and concrete actions need to be developed to combat the increase of MDR-TB.

scholarly journals An inexpensive, efficient and safe regimen containing Pasiniazid for MDR-TB in high Tuberculosis epidemic areas – A prospective study in China

2020 ◽  
Author(s):  
Wenwen Sun ◽  
Qin Tang ◽  
Jie Wang ◽  
Jinhui Yang ◽  
Fangyou Yu ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Success Rate ◽  
Treatment Success ◽  
Multidrug Resistant ◽  
P Value ◽  
Prospective Clinical Study ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb ◽  
A Prospective Study

Abstract Background: MDR-TB（multidrug-resistant tuberculosis） remains the challenge with low success rate of treatment. Pasiniazid had been applied in China for two decades, but relevant clinical studies are rare. To verify the efficacy and safety of a regimen containing pasiniazid on MDR-TB, a prospective clinical study was conducted in China. Methods: Patients with MDR-TB satisfied with inclusion criteria were prospectively enrolled into the study from 2017 June to 2018 Dec, given the regimen and followed up, observed the treatment outcome and adverse effect of drugs made up the regimen.Results: A total of 114 patients diagnosed as MDR Pulmonary tuberculosis(MDR-PTB) were enrolled into the study and given the regimen with six months of Capremycin(Cm), Levofloxacin(Lfx), Cycloserine(Cs), Protionamide(Pto), Pyrazinamide(Z) and Pasiniazid（Pa）, followed by 12 months of LfxCsPtoZPa. The overall treatment success rate in all enrolled patients was 79.8% (91/114) while it was significantly higher in newly treated MDR-PTB (91.7%, 33/36) than that in retreated MDR-PTB(74.4%，58/78, p value was 0.03); Patients infected with strains resistant to fluoroquinolones impacted the treatment outcome (P<0.05) while other drugs did not (P >0.05). Pasiniazid was taken safely without adverse reaction during the course of treatment.Conclusions: The long term of anti-MDR-PTB regimen containing Pasiniazid was proved to be effective, safe and inexpensive although it contained injectable agents. This regimen is suited to be applied in areas with poor resource and high TB burden.

scholarly journals FACTORS RELATED TO THE SUCCESS OF THE TREATMENT PROGRAM OF MULTIDRUG-RESISTANT TUBERCULOSIS IN POLYCLINIC OF MDR-TB OF THE GENERAL HOSPITAL OF UNDATA PALU, INDONESIA

2017 ◽  
Vol 3 (4) ◽  
pp. 162-166
Author(s):  
Muhammad Ryman Napirah ◽  
Bertin Ayu Wandira ◽  
Ana Aulia
Keyword(s):  
Side Effects ◽  
General Hospital ◽  
Multidrug Resistant ◽  
Drug Control ◽  
Drug Side Effects ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb ◽  
The Government

Background: Incidence of Multi Drug Resistant Tuberculosis remains high in Indonesia. Thus, understanding the factors related to the success of the Government Program on the treatment of Multidrug-resistant is necessity. Objective: This study aims to determine the factors related to the success of government programs on the treatment of MDR-TB patients in Polyclinic of MDR-TB of Undata Palu Hospital.Methods: This was a correlational study with cross-sectional design conducted in the polyclinic of MDR-TB of the General Hospital of Undata Palu from October 2016 to November 2016. There were 46 patients recruited by total sampling. Chi-square was used for data analysis.Results: Findings showed that there were statistically significant correlations between knowledge (p = 0.002), the regularity of treatment (p = 0.000), the role of drug control (p = 0.010), drug side effects (p = 0.000) and quality of service of health workers (p = 0.001) with the success of multidrug-resistant tuberculosis program. There was no correlation between distance to health facilities (p = 0.315) and the success of the treatment.Conclusion: There were significant relationships between knowledge, regularity of treatment, drug control, drug side effects, quality of health staffs and the success of multidrug-resistant tuberculosis program. These factors could be considered important for the government to the success of multidrug-resistant tuberculosis program, especially in the polyclinic of MDR-TB of the General Hospital of Undata Palu.

scholarly journals Faktor Risiko Yang Berpengaruh Pada Kejadian Tuberkulosis dengan Multidrug-Resistant Tuberculosis (MDR-TB) di RSUD Ulin Banjarmasin

2020 ◽  
Vol 7 (2) ◽  
pp. 139
Author(s):  
Aulia Mashidayanti ◽  
Nurlely Nurlely ◽  
Nani Kartinah
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Research Method ◽  
Multidrug Resistant ◽  
P Value ◽  
Cross Sectional ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Mdr Tb ◽  
Cross Sectional Design

MDR-TB (Multidrug-Resistant Tuberculosis) adalah salah satu jenis TB yang resisten dengan OAT (Obat Anti Tuberculosis) dengan resisten terhadap 2 obat anti tuberculosis yang paling ampuh yaitu rifampisin dan isoniazid. Obat rifampisin dan isoniazid sudah tidak efektif dalam membunuh kuman mycobacterium tuberkulosis dikarenakan kuman yang sudah resisten terhadap obat tersebut. MDR-TB merupakan suatu permasalahan yang menjadi hambatan utama dunia dalam pemberantasan TB. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor risiko apa saja yang dapat berpengaruh pada kejadian tuberkulosis dengan multidrug-resistant tuberculosis (MDR-TB) di RSUD Ulin Banjarmasin dengan variabel yang ditinjau adalah pengetahuan, motivasi dan keteraturan minum obat. Metode penelitian dengaan rancangan Cross Sectional dengan metode pengambilan dengan kuesioner. Populasi dalam penelitian ini adalah seluruh pasien dengan diagnosis tuberkulosis multidrug resistant tuberculosis (MDR-TB) dan pasien TB Non MDR yang digunakan sebagai pembanding yang dipilih secara acak. Hasil pada penelitian ini menunjukkan bahwa faktor risiko yang terbukti berpengaruh pada kejadian TB-MDR adalah keteraturan minum obat (p-value< 0,05). Oleh karena itu, untuk mengurangi potensi bertambahnya penderita TB-MDR, maka perlu diperhatikan lagi keteraturan minum obat penderita, memastikan agar penderita benar-benar rutin dan teratur dalam minum obat.  MDR-TB (Multidrug-Resistant Tuberculosis) is one of tuberculosis characterized by resistant to anti-TB drug (Anti Tuberculosis Drug). An MDR-TB event is a resistance event to 2 of the most effective anti-TB drugs which are rifampicin and isoniazid. Rifampicin and isoniazid are no longer effective in killing Mycobacterium tuberculosis bacteria due to its resistant to the drug. The purpose of this study is to identify any risk factors that can affect the incidence of tuberculosis with multidrug-resistant tuberculosis (MDR-TB) in RSUD Ulin Banjarmasin. The variables in this study were knowledge, motivation and regularity of taking drugs. The research method was a cross sectional design using questionnaire to the patients. The population in this study was all patients with a diagnosis of multidrug resistant tuberculosis (MDR-TB) and non-MDR TB patients who used as a comparison which were selected randomly. The results of this study indicate that the risk factor that has been shown to influence the incidence of MDR-TB was the regularity of taking medication (p-value <0.05). Therefore, to reduce the potential of MDR-TB sufferers to increase, it is necessary to pay attention to taking drug regularity of patient, ensuring that the patient is really routine and taking medication regularly.Keywords: RSUD Ulin Banjarmasin, MDR-TB (Multidrug-Resistant Tuberculosis), Tuberculosis

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