scholarly journals The Effect of Insect Repellent Exposure on Leukocyte Profile and Histopathologic Findings in Lungs

2021 ◽  
Vol 12 (6) ◽  
pp. 7796-7803

Organophosphate compounds in insect repellent have a role in contributing to mosquito mortality but have toxic effects for humans when exposed for a long time. The research is aimed to analyze the effect of insect repellent exposure in blood leukocyte profile and histopathologic findings in lungs. The study used thirty males Rattus novergicus, which were divided into three groups, such as electric liquid insect repellent (P1) with contain 0.031% dimefluthrin, anti-mosquito coils (P2) with 0.014% dimefluthrin, and electric mat mosquito repellent with 0.566% dimefluthrin for 8 hours in 20 days respectively. Leukocyte profiles were determined by using the blood smear method, and the lung’s health was identified by histopathologic findings. Based on the results study showed mosquito coils exposure increase the lymphocytes count. Meanwhile, the electric liquid-repellent increased the basophil’s numbers. The electric mat exposure had more eosinophils, neutrophils stab, neutrophils segment, and monocytes in the blood. The leukocyte profile of each group showed there were no statistically significant differences (P-value > 0.05). Based on histopathology, lung findings showed that the electric mat exposure contributed to cells degeneration 7.5% and pleural thickening 30%. The higher dimefluthrin concentrations in insect repellents could affect leukocyte profile and lungs health.

SCISCITATIO ◽  
2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Djoko Rahardjo ◽  
Vinsa Cantya Prakasita ◽  
Marlen Aviati Sarah Pepiana

Malaria is known as an endemic disease that often causes death in Indonesia, especially in Papua. The malaria cases control in Papua has not been carried on based on data studies, therefore bionomic of Anopheles sp is important to be studied. Bionomics data are consisted of breeding places, resting places and feeding habits are from direct observation. Interviews and questionnaires were conducted to gain information about respondent behavior. Descriptive and qualitative data were then analyzed. The breeding places of Anopheles sp. were mostly found in swampy areas. Based on the feeding habit, the feeding activity of Anopheles sp. inside the house has only one biting peak at 23.00-02.00 WIT, while outside the house, biting peaks occurred at 21.00-22.00 WIT and 00.00-01.00 WIT. Resting place data shown that Anopheles sp. mostly found in piles of clothes and shoe racks. Recorded factors that affect mosquitos bionomics are temperature, humidity, salinity, pH, community behavior, and the presence of livestock. Environmental factors (temperature, humidity, salinity, and pH), habitual behavior of host (3M action, the habit of using insect repellent, mosquito repellent, and mosquito nets), the presence of livestock, and the type of bait blood type affect mosquito activity.


2019 ◽  
Vol 4 (2) ◽  
pp. 89-101
Author(s):  
Samfriati S ◽  
Lilis N ◽  
Mercy N G

Academic procrastination is one of the postponement behaviors in lecture activities that are often found in students, in this study respondents experiencees a high level of procrastination that could hamper academic activities. One of the causes of procrastination is the use of gadgets that are too long to play games, music, entertainment and so on. Goals : The purpose of this study is to find out the relationship between the use of gadgets and academic procrastination onNursing Students level II Saint Elisabeth Medan 2019. Method : The study design is Cross Sectional. Total sampling technique sample are112 students. The measuring instrument used is a questionnaire. Result : The results shows that the majority of use of positive gadgets (92.9%) and moderate academic procrastination (63.4%). Based on the Fisher's Exact Test, it obtained p-value 0.026 (p <0.05), thus indicating a relationship between the use of gadgets and academic procrastination on nursing students level II STIKes Saint Elisabeth Medan. Conculsion: It is expected that respondents will be able to manage time well and not use gadgets for a long time for things that are not useful. Respondent s are expected to use gadgets for things that can support learning activities.


2018 ◽  
Vol 13 (2) ◽  
pp. 29
Author(s):  
Paolo Pietro Biancone ◽  
Silvana Secinaro ◽  
Valerio Brescia

Local health companies have been trying to report quantitative and qualitative information through social reporting tools for a long time. The OECD has been questioning for quite some time how to evaluate satisfaction and quality by not considering the economic aspect alone in the quest for satisfying the needs of the citizen. The aim of the work is to evaluate how the compound indicator of well-being perceived by the population and the composite indicator of the quality of health services can be used to define health policies considering the incidence of other variables. In the analysis, it is therefore assessed how much the two indicators are related and linked to other variables that need to be considered and how independent indicators are used without further evaluations to target policies. The data are updated to October 18, 2017. All statistical analyses were performed using STATA V.13 (Stata Corp, College Station, Texas, USA, 2013) and p value <0.05 was considered significant for all analyses. The sample is made up of 35 OECD countries.


2021 ◽  
Author(s):  
Daniel Msellemu ◽  
Amanda Ross ◽  
Lucky Temu ◽  
Irene Moshi ◽  
Lorenz Hofer ◽  
...  

Abstract Background: While there is strong evidence that permethrin-treated clothing and topical insect repellents are protective against insect bites, there are few studies assessing the impact on malaria infection. This study will evaluate the impact of the protective efficacy of bite prevention methods on the incidence of malaria infection among military personnel in an operational setting. Permethrin-treated uniforms will be compared to etofenprox-treated uniforms, with both clothing treatments used in conjunction with DEET insect repellent. An additional study arm will test permethrin uniforms with placebo lotion to determine if there is any additional protective effect of using DEET with insecticide-treated clothing. Method: A cluster randomised double-blind placebo-controlled trial is planned to evaluate the effectiveness of the interventions on preventing malaria infections in soldiers on active duty at Mgambo National Service Camp in Tanga, Tanzania. The arms are (1) permethrin-treated uniform with 30% DEET liposome formula; (2) permethrin-treated uniform with placebo lotion; (3) candidate insect repellent system, i.e., etofenprox-treated uniform with 30% DEET liposome formula; and (4) placebo, i.e., untreated uniforms with placebo lotion. The primary outcome is the incidence of Plasmodium falciparum malaria infection detected by polymerase chain reaction (PCR) by active case detection using surveys every 2 weeks for 12 months. Rapid diagnostic tests will be used for diagnosis of participants with symptoms. The unit of randomisation will be combania: companies formed by recruits aged 18 to 25 years; combania do activities together and sleep in the same dormitory. Unequal randomisation will be used to optimise statistical power for the primary comparison between permethrin-treated uniforms with DEET and etofenprox-treated uniforms with DEET. Discussion: This trial will estimate the effects of permethrin with DEET compared to those of the new fabric treatment etofenprox with DEET and any additional effect of using DEET. The results will inform strategies to protect military personnel and civilians who have more outdoor or occupational malaria exposure than the general public. Trial registration: clinicaltrials.gov Registration number NCT02938975.


2019 ◽  
Vol 2 (2) ◽  
pp. 407
Author(s):  
Sarce Babra Awom

The purpose of this study was to measure the effect of venture capital (X1)  and the long time at sea /time work hours (X2) for the offer price of fish (Y) in the tradisional sanggeng market manokwari, with 73 respondents chosen randomly and consisted of sellers and buyers in the sanggeng market. Data  collection  methods are done through interviews,  (primary data)  with a questionnaire and then  carried out  a questionnaire  test  and test the quality of the data, and then analyzed uiple linear regression. The result of research simultan eously or statistically partial variables X1 (venture capital) and variable X2 (long sea)  significantly influence the higt selling price of fish (variable y) in the manokwari sanggeng market  because the value of p. Value (0,000)<(0.05) sig (5%.) so it can be concluded that when fish traders increase capital by 1% the price of fish in the market rises by 13,5% and also when a long time to go to sea increases 1 day than the price of fish increases by  33.900,00. The government needs to control high (expensive) fish prices in the market by activating an inflation control team that continues to monitor the market price (specifically) of the fisheries sector.


2020 ◽  
Vol 5 (1) ◽  
pp. 41-47
Author(s):  
Rina Kurnia

Abstract Background: Musculoskeletal complaints are discomforts to the pain experienced by someone that is triggered by a body that receives statistics, or performs activities in a less ergonomic position repeatedly for a long time. One result of musculoskeletal is a decrease in quality of life. Efforts that can be made to improve the quality of life with musculoskeletal complaints are a combination of low-impact aerobics with routine stretching exercises. This study aims to determine the effectiveness of Aerobic Low Impact with Stretching Exercise on the Quality of Life of Mothers with Musculoskeletal Complaints in Ngegot Selokaton Gondangrejo Karanganyar Hamlet. Method: The design of this study was a pretest-posttest experimental design. Sampling was done by purposive sampling technique. Quality of life complaints data was taken using the WHOQOL-BREF instrument. Results: The results of research through the Wilcoxon statistical test and paired t-test on the domain of quality of life obtained the same results, namely p value = 0.001. Conclusion: The combination of low impact aerobics with stretching exercises is effective to improve the quality of life of mothers with musculoskeletal complaints about Ngegot Selokaton village. Gondangrejo Karanganyar sees from 4 domains of quality of life on the WHOQOL-BREF instrument (health, psychological, social, social, and social)   Keywords: Low impact aerobics, stretching exercises, quality of life


Author(s):  
Jbireal JM ◽  
Azab Elsayed Azab ◽  
Alzahani S ◽  
Elshareef M

Background: Chronic myeloid leukemia (CML) is a clonal myeloid proliferative disorder of primitive haemopoietic progenitor cells. The incidence of CML ranges between 10 and 15 cases/106 /year without any major geographic or ethnic differences. Imatinib mesylate provides good results in the treatment of CML. Early studies demonstrated that Imatinib mesylate can produce clear hematologic and cytogenetic response when used as a treatment of CML patients with positive BCR-ABL gene. Nevertheless, some patient with different stages of CML (chronic, accelerated, or acute phases) either relapse or stay unchanged for a long time after initial doses of treatment. This phenomenon led to the fact that we must explore the possible changes expected to appear if we make some changes in the treatment strategy. Objectives: The present study aimed to evaluate hematologic and molecular responses of CML patients to Imatinib mesylate treatment. Methods: Eighteen CML patients in chronic phase aged (24–65 years) males and females were treated with Imatinib mesylate (400, 500 or 600 mg/day) for sixteen months. Hematologic and cytogenetic changes were analyzed periodically. Results: Overall 18 cases, hematologic response of 14 cases was complete white blood cells (WBCs) decrease to normal range within 4 months) with P value of less than 0.0001 whereas in 4 cases WBCs were decreased slowly (after 8 months). A major cytogenetic response was noticed in 4 cases while in others the response was partially or in minor range. The major hematologic and cytogenetic response was noticed when using 600mg/day of Imatinib mesylate. The correlation appeared as a significant positive correlation between the treatment doses and Hb, hematocrit, MCV, MCH, esinophils%, and monocytes %. And a significant negative correlation between the treatment doses and RDW %, platelets count, WBCs count, and basophils %. On the other hand, no correlation between the treatment doses and RBCs Count, MCHC, Neutrophil % and BCR/APL ratio % Conclusion: It can be concluded that treatment of CML patients with Imatinib mesylate caused complete WBCs decrease to normal range. The major hematologic and cytogenetic response was noticed when using a higher dose of Imatinib mesylate.


Author(s):  
Dewi Pusparani Sinambela ◽  
St. Hateriah

Latar Belakang: Lama Kala II dalam persalinan yaitu jangka waktu mulai dari serviks berdilatasi penuh sampai dengan kelahiran bayi tidak boleh melebihi 2 jam pada primigravidan dan 1 jam pada multigravida. Pemilihan posisi melahirkan sangat dianjurkan untuk memberikan rasa nyaman pada ibu, posisi dapat membantu penurunan janin ke dasar panggul dan mempercepat proses persalinan. Dari data yang diperoleh bulan Januari 2018 jumlah persalinan kala II lama sebanyak 0,30% dari 240 persalinan normal.Tujuan: Menganalisis Perbedaan Posisi Meneran Miring Kiri dan Setengah Duduk Pada Ibu Bersalin Dengan Lama Kala II.Metode: Jenis penelitian ini adalah Analisis kuantitatif. Rancangan penelitian menggunakan quasi eksperiment. Populasi penelitian semua ibu bersalin di RSUD Dr. H. Moch Anshari Saleh Banjarmasin. Pengambilan sebanyak 30 responden. Pengambilan data dilakukan dengan menggunakan ceklist. Analisa data yang dilakukan adalah Analisa Univariat dan Analisa Bivariat dengan uji Fisher Exact Test.Hasil: Responden yang menggunakan posisi meneran miring kiri 15 orang (50%) dan setengah duduk sebanyak 15 orang (50%). Jumlah responden primipara yang mengalami persalinan kala II 60 menit sebanyak 12 orang (40,0%), primipara yang mengalami kala II 60 menit sebanyak 2 orang (6,7%) dan responden multipara yang mengalami kala II 30 menit sebanyak 16 orang (53,3%), multipara yang mengalami kala II 30 menit sebanyak 0 orang (0%) dari hasil uji Fisher Exact Test dengan nilai p sebesar 0,483.Simpulan: Tidak ada perbedaan posisi miring kiri dengan posisi setengah duduk terhadap kemajuan persalinan kala II di RSUD Dr. H. Moch. Anshari Saleh Banjarmasin. Kata Kunci: Lama Kala II, Persalinan, Posisi Meneran.   Analysis of Different Left and Half Posisition Straining on Mother with Second Duration of Labour In RSUD Dr. H. Moch Anshari Saleh BanjarmasinABSTRACT Background: The duration of second stage of labor is the period from the full dilated cervix to the birth of the baby should not exceed 2 hours in primigravida and 1 hour in multigravida. Position selection is very beneficial for giving comfort to the mother, the position can help lower the fetus to the pelvic floor and improve labor. From the data obtained in January 2018 the number of prolonged second stage deliveries was 0.30% of 240 normal deliveries.Objective: Analyze the Differences in Position Meniring Left and Half Seated at the Maternity with Long Time II.Method: This type of research is quantitative analysis. The study design used quasi experiment. The study population of all mothers giving birth at Dr. RSUD H. Moch Anshari Saleh Banjarmasin. Taking as many as 30 respondents. Data retrieval is done using a checklist. Data analysis performed was Univariate Analysis and Bivariate Analysis with Fisher Exact Test.Results: Respondents who used the left oblique piercing position were 15 people (50%) and half sat as many as 15 people (50%). The number of primiparous respondents who increased labor at second time 60 minutes was 12 people (40.0%), primipara who added second stage 60 minutes as many as 2 people (6.7%) and multiparous respondents who used second time 30 minutes as many as 16 people (53.3%), multiparas who replaced time II 30 minutes as many as 0 people (0%) from the results of the Fisher Exact Test with a p value of 0.483.Conclusion: There was no difference in left oblique position with sitting position towards the progress of second stage labor in Dr. Hospital. H. Moch. Ansari Saleh Banjarmasin.  Keywords : Second Duration, Labour, Straining Position 


2021 ◽  
Vol 15 (8) ◽  
pp. 1923-1926
Author(s):  
Hafsah Arshad ◽  
Hafsah Gul Khattak ◽  
Kinza Anwar ◽  
Hazrat Bilal

Aim: This study was conducted to determine the prevalence of musculoskeletal pain disorders and related factors among female school teachers of Peshawar. Methodology: A descriptive cross-sectional survey was conducted from February 2019 to July 2019 among primary and secondary female school teachers (n=289) in Peshawar. Data was collected from using semi-structured questionnaire. Outcome measures were based on modified version of Nordic musculoskeletal questionnaire (NMQ) and Numeric Pain Rating Scale (NPRS). Descriptive statistics was used to summarize qualitative variables in the form of frequencies and percentages. Mean and standard deviation was calculated for quantitative variables. Chi-square test was used to find association. The significant P value was <0.05. Results: Prevalence of musculoskeletal pain disorders was 82.7%. The overall mean age of sample was 37.5±8.47. Most common sites of pain were low back 60.2% followed by neck pain 50.2%, ankle pain 48.4% and shoulder pain 44.3%. Factors that showed significant relationship were long time standing (p=0.001), long time sitting (p=0.039), checking copy/paper marking (p value 0.023) and uncomfortable work chair/table (p = 0.012). Conclusion: Female school teachers showed high prevalence of musculoskeletal pain disorders, low back was the most common site for pain followed by ankle and shoulder. Risk factors associated with pain were long time standing, long time sitting, checking copy/paper marking and uncomfortable work chair/table. Keywords: Musculoskeletal disorder, ergonomics, Nordic musculoskeletal questionnaire, low back pain, neck pain.


2020 ◽  
Vol 12 (18) ◽  
pp. 2898
Author(s):  
Filipe Lisboa ◽  
Vanda Brotas ◽  
Filipe Duarte Santos ◽  
Sakari Kuikka ◽  
Laura Kaikkonen ◽  
...  

Monitoring lakes in high-latitude areas can provide a better understanding of freshwater systems sensitivity and accrete knowledge on climate change impacts. Phytoplankton are sensitive to various conditions: warmer temperatures, earlier ice-melt and changing nutrient sources. While satellite imagery can monitor phytoplankton biomass using chlorophyll a (Chl) as a proxy over large areas, detection of Chl in small lakes is hindered by the low spatial resolution of conventional ocean color satellites. The short time-series of the newest generation of space-borne sensors (e.g., Sentinel-2) is a bottleneck for assessing long-term trends. Although previous studies have evaluated the use of high-resolution sensors for assessing lakes’ Chl, it is still unclear how the spatial and temporal variability of Chl concentration affect the performance of satellite estimates. We discuss the suitability of Landsat (LT) 30 m resolution imagery to assess lakes’ Chl concentrations under varying trophic conditions, across extensive high-latitude areas in Finland. We use in situ data obtained from field campaigns in 19 lakes and generate remote sensing estimates of Chl, taking advantage of the long-time span of the LT-5 and LT-7 archives, from 1984 to 2017. Our results show that linear models based on LT data can explain approximately 50% of the Chl interannual variability. However, we demonstrate that the accuracy of the estimates is dependent on the lake’s trophic state, with models performing in average twice as better in lakes with higher Chl concentration (>20 µg/L) in comparison with less eutrophic lakes. Finally, we demonstrate that linear models based on LT data can achieve high accuracy (R2 = 0.9; p-value < 0.05) in determining lakes’ mean Chl concentration, allowing the mapping of the trophic state of lakes across large regions. Given the long time-series and high spatial resolution, LT-based estimates of Chl provide a tool for assessing the impacts of environmental change.


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