scholarly journals Morbidity of different treatment modalities in advanced Carcinoma larynx

2015 ◽  
Vol 20 (2) ◽  
pp. 66-74
Author(s):  
Md Sirajul Islam Mahfuz ◽  
Belayat Hossain Siddiquee ◽  
A Allam Choudhury ◽  
Shaikh Muniruddin Ahmad
Keyword(s):  
Cross Sectional Study ◽  
Treatment Modalities ◽  
Glottic Carcinoma ◽  
Neck Node ◽  
Cross Sectional ◽  
Advanced Carcinoma ◽  
Carcinoma Larynx ◽  
Neck Node Metastasis ◽  
The Difference ◽  
Almost All

Objectives: To evaluate morbidity of different modalities of treatment in advanced carcinoma larynx (stage III and IV). Methods: It was a cross sectional study conducted among selected 70 patients of advanced carcinoma larynx treated by different modalities of treatment from April 2009 to April 2010 in different tertiary hospitals in Dhaka. Results:The age of the patients ranged from 30 to 79 years (mean ± SD = 54±10.94), maximum age incidence 5th decade. Almost all were male, habituated in betel nut and leaves chewing and smoking. Mostly (60%) from poor socioeconomic group. 70% cases were supraglottic and 30% cases were glottic carcinoma. Nature of lesion was exophytic 71.43% and ulcerative 28.57%. 22.86% had neck node metastasis. Histopathologically 60% were moderately differentiated and grade II squamous cell carcinoma (SCC). In the total laryngectomy patient pharyngocuteneous fistula (30%), wound infection (10%), haematoma (10%), stomal recurrence (10%), stenosis is tracheostomy (10%), recurrent chest infection (10%) and pharyngeal stenosis (10%) were the morbidities. Mucositis or painful erythematous reaction in larynx and pharynx (95%), periconditis (2.5%), dryness of mouth and throat (100%), loss of test (100%), subcutaneous fibrosis (32.5%), nausea vomiting, skin rashes and alopecia (100%) were the morbidities of chemoradiotherapy and radiotherapy. After analysis the major and minor morbidities of different, modalities of treatment there was no significant (p > 0.05) difference among those modalities. Conclusion: The difference between the morbidity of single modality and combined modalities had not significant. So the combined modalities approach may be advocated for the treatment of advanced carcinoma larynx where required. DOI: http://dx.doi.org/10.3329/bjo.v20i2.22021 Bangladesh J Otorhinolaryngol; October 2014; 20(2): 66-74

scholarly journals Contraceptive User’s Profile

2016 ◽  
Author(s):  
Eka R Gunardi
Keyword(s):  
Obstet Gynecol ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Contraceptive Methods ◽  
Cross Sectional ◽  
Study Population ◽  
The Mean ◽  
The Difference ◽  
Almost All ◽  
The Cost

Objective: To obtain informations regarding the profile of contraceptive users in Raden Saleh Clinic, Jakarta. Method: A cross-sectional study was conducted in June 2012, at Raden Saleh Clinic, Jakarta. The study population was the patient who came to Raden Saleh Clinic from 2008 until 2011. Results: The mean age of the contraception users was 34.06 and the mean of their husband’s age was 38.91 years old. Most of the patients were graduated from senior high school (43.2%) and university (37.9%). More than half of the patients (55.2%) were not working and more than a half of their husband (53.2%) were private employee. Almost all (92.6%) of the patient were married. Most of the patient (38.8%) came with no prior contraception. After consultation, all patients had chosen their preferred contraceptive methods, namely IUD (61.4%), injectable contraception (20.9%), pill (13.7%), sterilization (3.4%), and implant (0.6%). Conclusion: Family planning reduces maternal mortality and the best method is different for each patient because of the difference in their own condition and the consideration of the cost and benefit. [Indones J Obstet Gynecol 2013; 1-4:179-82] Keywords: contraception, contraceptive users profile

scholarly journals Patients’ experiences of the use of point-of-care ultrasound in general practice – a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Camilla Aakjær Andersen ◽  
John Brodersen ◽  
Torsten Rahbek Rudbæk ◽  
Martin Bach Jensen
Keyword(s):  
General Practice ◽  
Point Of Care ◽  
Cross Sectional Study ◽  
Future Research ◽  
Point Of Care Ultrasound ◽  
Cross Sectional ◽  
Final Questionnaire ◽  
The Difference ◽  
Point Of Care Ultrasonography ◽  
Almost All

Abstract Background The use of point-of-care ultrasonography (POCUS) performed by general practitioners (GPs) in primary care settings is increasing. Previous studies have focused on GP-reported outcomes and little is known about patients’ perspectives on the use of POCUS technology within the general practice consultation. The purpose of this study was to examine patients’ experiences with POCUS in general practice within the areas where GPs have indicated that POCUS affected aspects of the consultation. Methods A questionnaire was developed using a mixed methods sequential design. Analytical themes from interviews with GPs were converted into items in a questionnaire by the research team. The questionnaire was then further developed in several rounds of pilot tests involving both patients and GPs. The final questionnaire was used in a cohort study conducted in 18 Danish office-based general practice clinics from January 2018 to August 2018. All patients examined with POCUS were asked to complete the questionnaire on tablets immediately after their consultation. Results Out of 691 patients examined, 564 (81.6%) questionnaires were available for analysis. The patients reported that they were well informed about the purpose (98%) and the results (97%) of the POCUS examination; however, 29% reported that they were not informed about the difference between POCUS and an imaging-specialist’s ultrasound examination. Almost all patients (99%) reported that POCUS was integrated naturally into the consultation, and 45% reported that POCUS improved the doctor-patient relationship. The majority of patients felt that they had been more thoroughly examined (92%) and taken more seriously (58%) when POCUS was part of the consultation. They felt POCUS gave them a better understanding of their health problem (82%), made them feel more secure (86%) and increased their trust in the physician’s assessment (65%). Moreover, the patients reported that POCUS use improved the level of service (95%) they experienced and the quality of care (94%) in general practice. Conclusion We found that an examination including POCUS in general practice was a positive experience overall for the majority of patients. Future research should further explore reasons for patient confidence in POCUS and whether or not the reassuring value of POCUS is valid. Trial registration ClinicalTrials.gov Identifier: NCT03416608

scholarly journals Pattern of Neck Node Metastasis in Laryngeal Carcinoma

2019 ◽  
Vol 24 (2) ◽  
pp. 115-124
Author(s):  
Md Momin Uddin ◽  
Samia Quadir ◽  
Kazi Shameemus Salam ◽  
Mohammed Abdus Sattar ◽  
Md Mosleh Uddin ◽  
...  
Keyword(s):  
Laryngeal Carcinoma ◽  
Cervical Lymph Node Metastasis ◽  
Glottic Carcinoma ◽  
Neck Node ◽  
Major Health Problem ◽  
Carcinoma Larynx ◽  
Betel Leaf ◽  
Node Metastasis ◽  
Neck Node Metastasis ◽  
Level Ii

Background: Cancer continues to be a major health problem despite advances in medical technology for its diagnosis and treatment. Cancer of the larynx is the eleventh most common cancer in the world. Carcinoma larynx is a multifactorial disease. Smoking, betel-nut, betel-leaf chewing habit and drinking alcohol are the most important factors associated with carcinoma larynx. Objective: To detect the rate and level of cervical lymph node metastasis in laryngeal carcinoma Methods: Detailed information was obtained in each cases according to protocol. Complete history was taken from accompanying attendants. Thorough clinical examination was done. All the information’s were recorded in the fixed protocol. Patients were randomly assigned to one of three groups by card sampling. Collected data were classified, edited, coded and entered into the computer for statistical analysis by using updated computerized program SPSS-19 Results: Out of 50 cases the mean average age was found 58.5±11.9 years with range from 39 to 78 years. Majority (70.0%) patients presented with supraglottic carcinoma followed by 13(26.0%) glottic carcinoma and 2(4.0%) subglottic carcinoma. More than three fourth (78.0%) patients had difficulty in swallowing followed by 17(34.0%) had hoarseness of voice, 12(24.0%) had discomfort in throat, 10(20.0%) had earache, 6(12.0%) had hemoptysis and 4(8.0%) had cough. Majority (42.0%) patients were found N0 followed by 15(30.0%) N1, 13(26.0%) N2 and 1(2.0%) N3 of neck node. Majority (42.0%) patients was found in stage T3 followed by 7(14.0%) in stage T1, 18(36.0%) in stage T2 and 4(8.0%) in stage T4. Majority (56.0%) patients was found in level-II of neck nodes followed by 12(24.0%) level III, 4(8.0%) level IV, 3(6.0%) level II+III, 2(4.0%) level III+IV and 1(2.0%) level III+IV+V of neck nodes. Conclusion: Laryngeal carcinoma is a common clinical entity in otolaryngology practice. Male were more predominant and the highest age group was 51-60 years. In our study most common Laryngeal carcinoma was supraglottic in nature. T3 was the commonest stage of involvement. Common clinical presentation was difficulty in swallowing and hoarseness of voice. N 0 and N1 was the most common pattern of neck node metastasis. In our series majority of them were in level II  Bangladesh J of Otorhinolaryngology; October 2018; 24(2): 115-124

scholarly journals Topographical Distribution of Carcinoma Larynx

2020 ◽  
Vol 24 (1) ◽  
pp. 56-61
Author(s):  
Md Shahjad Selim ◽  
Md Mozharul Islam ◽  
Md Manjur Rahim ◽  
Md Hasan Zafar ◽  
Md Khalid Asad ◽  
...  
Keyword(s):  
Laryngeal Carcinoma ◽  
Primary Tumour ◽  
Neck Region ◽  
Cross Sectional Study ◽  
Glottic Carcinoma ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
Carcinoma Larynx ◽  
Topographical Distribution

The larynx is the most common site for primary tumour of the head and neck region. It represents world wide approximately 1-2% of all cancers. A cross sectional study of 154 cases of laryngeal carcinoma was carried out in the in-patient department of Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College during the period of two years with an aim to find out the frequency of site and subsite involvement of carcinoma of the larynx. The age range is 33-80 years and the over all male to female ratio is 29.8:1. Smoking and chewing habit are the most important associated factors. Majority of growths are found to be exophytic and most of the patients present at advanced stage. The commonest site of laryngeal carcinoma is supraglottic region and occurrence of supraglottic carcinoma than glottic carcinoma is statistically highly significant. Bangladesh J Otorhinolaryngol; April 2018; 24(1): 56-61

Perceived social support and burden of care of male and female caregivers of patient with schizophrenia

2017 ◽  
Vol 8 (1) ◽  
pp. 10
Author(s):  
Narendra Kumar Singh ◽  
Nishant Goyal
Keyword(s):  
Social Support ◽  
Perceived Social Support ◽  
Family Members ◽  
Well Being ◽  
Cross Sectional Study ◽  
Burden Of Care ◽  
Cross Sectional ◽  
Male And Female ◽  
The Social ◽  
The Difference

Background: Schizophrenia is associated with a high familial, social and economic burden. Schizophrenia is also associated with a high level of disability which may create impediments on the social and economic areas of the patients as well as on their respective family networks. Families with schizophrenia may encounter problems such as impairment of health and well being of other family members, restriction of social activities of the family members and shrinking of support from the social network. Aims: The present study examined the difference in perceived social support and burden of care between the male and female caregivers of patients with schizophrenia. Methods: This was a cross-sectional study examining the difference in perceived social support and burden of care between the male and female caregivers of patients with schizophrenia. The sample consisted of 60 (30 male and 30 female) caregivers of the patients with the diagnosis of schizophrenia as per ICD-10-DCR. Results and Conclusion: This study revealed that male caregivers perceived more social support and less burden of care as compared to female caregivers. Key words: Gender, social support, burden

Hepatitis A Seroprevalence Among Patients with Chronic Hepatitis B Infection: A Cross-Sectional Study in Iran During 2016-2017

2020 ◽  
Vol 20 (5) ◽  
pp. 748-751
Author(s):  
Seyed Ali Dehghan Manshadi ◽  
Neda Alijani ◽  
Mohammadreza Salehi ◽  
Omid Dadras ◽  
SeyedAhmad SeyedAlinaghi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Hepatitis A ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Reasonable Approach ◽  
The Difference ◽  
Prevention Method

Introduction: The aim of this study was to determine the prevalence of exposure to hepatitis A by means of serologic markers in chronic hepatitis B patients, with the secondary aim of finding the best prevention method for hepatitis A infection in susceptible groups of our setting. Methods: During the period between 2016 and 2017, we recruited 403 hepatitis B patients aged more than 14 years and regularly attending the infectious diseases clinic at a referral university hospital, Tehran, Iran. A blood sample was collected from all the patients and tested for hepatitis A IgG. The data was analyzed by SPSS v.19. Results: Although none of the patients had previously received hepatitis A vaccine, the results for serologic level of hepatitis A IgG, demonstrated positive results in 379 (94%) cases. The mean age of patients with negative and positive IgG was 29.17 and 42.46 years, respectively; the difference was statistically significant (P≤0.001). The majority of seronegative patients were young adults aged < 25 years and 25 to 35 years (P <0.001). Conclusion: Seroprevalence of hepatitis A in chronic HBV patients in Iran is high. As HBV infected patients younger than 35 years could be seronagative for HAV infection, evaluation of these patients for HAV infection and vaccination of seronegative patients would be a reasonable approach.

Quality of life in Hungarian polio survivors

2021 ◽  
Author(s):  
Erika Viktória Miszory ◽  
Melinda Járomi ◽  
Annamária Pakai
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Sample Selection ◽  
Cross Sectional Study ◽  
Two Dimensions ◽  
Cross Sectional ◽  
Emotional Role ◽  
The Difference ◽  
Polio Survivors

Abstract Aim The number of Hungarian polio patients can be estimated at approximately 3000. Polio infection is currently affecting people 56–65 years of age. The aim of the study was to reveal the quality of life of patients living with polio virus in Hungary. Subject and methods The quantitative cross-sectional study was conducted in January–April 2017 among polyomyelitis patients living in Hungary. In the non-random, targeted, expert sample selection, the target group was composed of patients infected with poliovirus (N = 268). We have excluded those who refused to sign the consent statement. Our data collection method was an SF-36 questionnaire. Using the IBM SPSS Statistics Version 22 program, descriptive and mathematical statistics (χ2-test) were calculated (p < 0.05). Results The mean age of the members of the examined population is 63.5 years; 68.1% were women and 31.90% were men. The majority of the respondents were infected by the polyovirus in 1956 (11.9%), 1957 (24.3%), and 1959 (19.5%). Polio patients, with the exception of two dimensions (mental health, social operation), on the scale of 100 do not reach the “average” quality of life (physical functioning 23 points, functional role 36 points, emotional role 47 points, body pain 48 points, general health 42 points, vitality 50 points, health change 31 points). Conclusion The quality of life of polio patients is far below the dimensions of physical function, while the difference in mental health compared to healthy people is minimal. It would be important to educate health professionals about the existing disease, to develop an effective rehabilitation method.

scholarly journals The Pandemic and Changes in the Self-Perception of Teacher Digital Competences of Infant Grade Students: A Cross Sectional Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4756
Author(s):  
Rosalía Romero-Tena ◽  
Carmen Llorente-Cejudo ◽  
María Puig-Gutiérrez ◽  
Raquel Barragán-Sánchez
Keyword(s):  
Intervention Group ◽  
Cross Sectional Study ◽  
Self Perception ◽  
Digital Competence ◽  
Cross Sectional ◽  
Self Perceptions ◽  
Group A ◽  
Different Dimensions ◽  
The Difference ◽  
Group B

Without having a reaction time, the pandemic has caused an unprecedented transformation in universities around the world, leading to a revolution from structured models anchored in the conception of transmission of training towards a teaching approach-learning saved thanks to the incorporation of technology. This study aims to verify whether the pandemic situation has influenced the digital competence self-perception of students. Comparing two groups during the academic years 2019/2020 and 2020/2021, the instrument used is the questionnaire for digital competence “DigCompEdu Check-In” for future teachers. After the educational intervention, group A (before COVID-19) presented higher self-perceptions of competence than group B (during COVID-19); the pandemic situation caused by COVID-19 has negatively influenced students’ self-perception of their digital skills in the pretest in the different dimensions under study. Before receiving the training, the group that did not experience the pandemic enjoyed a higher self-perception of their competencies than the group that experienced the pandemic. The data obtained indicate that the difference exists, and that it is statistically significant, and may be a consequence of the clear relationship between self-perception and the way in which students face reality through their personal and subjective vision.

scholarly journals Thyroid cancer overdiagnosis and overtreatment: a cross- sectional study at a thyroid cancer referral center in Ecuador

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Paola Solis-Pazmino ◽  
Jorge Salazar-Vega ◽  
Eddy Lincango-Naranjo ◽  
Cristhian Garcia ◽  
Gabriela Jaramillo Koupermann ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Mortality ◽  
Incidental Finding ◽  
Cross Sectional Study ◽  
Anaplastic Carcinoma ◽  
Treatment Modalities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Referral Center ◽  
Clinical Records

Abstract Background In contrast to the rapid increase in thyroid cancer incidence, the mortality has remained low and stable over the last decades. In Ecuador, however, thyroid cancer mortality has increased. The objective of this study is to determine possible drivers of high rates of thyroid cancer mortality, through a cross-sectional analysis of all patients attending a thyroid cancer referral center in Ecuador. Methods From June 2014 to December 2017, a cross-sectional study was conducted at the Hospital de Especialidades Eugenio Espejo, a regional reference public hospital for endocrine neoplasia in adults in Quito, Ecuador. We identified the mechanism of detection, histopathology and treatment modalities from a patient interview and review of clinical records. Results Among 452 patients, 74.8% were young adults and 94.2% (426) were female. 13.7% had a family history of thyroid cancer, and patients’ median tumor size was 2 cm. The incidental finding was 54.2% whereas 45.8% was non-incidental. Thyroid cancer histology reported that 93.3% had papillary thyroid cancer (PTC), 2.7% follicular, 1.5% Hurtle cells, 1.6% medullary, 0.7% poor differentiated, and 0.2% anaplastic carcinoma. The mean MACIS (metastasis, age, completeness, invasion, and size) score was 4.95 (CI 4.15–5.95) with 76.2% of the thyroid cancer patients having MACIS score less than or equal to 6. The very low and low risk of recurrence was 18.1% (79) and 62% (271) respectively. An analysis of 319 patients with non-metastatic thyroid cancer showed that 10.7% (34) of patients had surgical complications. Moreover, around 62.5% (80 from 128 patients with thyroglobulin laboratory results) of TC patients had a stimulated-thyroglobulin value equal or higher than 2 ng/ml. Overall, a poor surgical outcome was present in 35.1% (112) patients. Out of 436 patients with differentiated thyroid carcinoma, 86% (375) received radioactive iodine. Conclusion Thyroid cancer histological characteristics and method of diagnosis are like those described in other reports without any evidence of the high frequency of aggressive thyroid cancer histology. However, we observed evidence of overtreatment and poor surgical outcomes that demand additional studies to understand their association with thyroid cancer mortality in Ecuador.

scholarly journals Six ultraviolet minutes for cleaner operating theatres

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Bosco ◽  
S Gambelli ◽  
V Urbano ◽  
G Cevenini ◽  
G Messina
Keyword(s):  
Cross Sectional Study ◽  
Cross Sectional ◽  
Before And After ◽  
Operating Theatres ◽  
Cleaning Procedures ◽  
The Difference ◽  
Contamination Levels ◽  
Different Levels ◽  
Better Than ◽  
Final Cleaning

Abstract Background Sanitizing the operating theatres (OT) is important to minimize risk of post-operative infections. Disinfection procedures between one operation and another is less aggressive than final cleaning procedures, at the end of the day. Aim was assessing the difference of contamination: i) between different levels of disinfection; ii) before and after the use of a UVC Device (UVC-D). Methods Between December 2019/February 2020 a cross sectional study was conducted in OT in a real clinical context. 94 Petri dishes (PD) were used in 3 OT. Three different sanitation levels (SL1-3) were compared pre- and post-use of UVC-D: i) No cleaning after surgery (SL1); ii) after in-between cleaning (SL2); iii) after terminal cleaning (SL3). UVC-D was employed for 6 minutes, 3 minutes per bed side. PD were incubated at 36 °C and colony forming unit (CFU) counted at 48h. Descriptive statistic, Wilcoxon and Mann-Whitney tests were performed to assess the contamination levels in total, pre/post use of UVC-D, and between different sanitation levels, respectively. Results In total we had a mean of 3.39 CFU/PD (C.I. 2.05 - 4.74) and a median of 1 CFU/PD (Min. 0 - Max. 39), after UVC-D use we had a mean of 2.20 CFU/PD (C.I. 0.69 - 5.09) and a median of 0 CFU/PD (Min. 0 - Max. 133). The UVC-D led to a significant reduction of CFU (p &lt; 0.001). Without UVC-D we had a significant CFU drop (p &lt; 0.05) between SL1 and SL3. Using UVC-D, we observed significant reductions of contamination (p &lt; 0.05) between SL3 and SL1. Comparing SL1 (median 0) post UVC-D use vs SL2 pre UVC-D use (median 0.5), and SL2 post UVC-D use (median 0) vs SL3 pre UVC-D use (median 1) we had a significant reduction of contamination (p &lt; 0.05). Conclusions UVC-D improved environmental contamination in any of the three sanitation levels. Furthermore, the use of UVC-D alone was better than in-between and terminal cleaning. Although these encouraging results, the cleaning procedures executed by dedicated staff has to be considered. Key messages UVC are efficient to decrease contamination in operating theatres regardless of sanitation levels. The additional use of UVC technology to standard cleaning procedures significantly improves sanitation levels.

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