scholarly journals A Lower Dose of Magnesium Sulphate for Control of Convulsion in Eclamptic Women of Bangladesh

2013 ◽  
Vol 25 (2) ◽  
pp. 71-76
Author(s):  
N Sultana ◽  
K Begum ◽  
A Begum ◽  
U Akhter

Eclampsia, a life threatening complication of pregnancy. It is one of the important cause of  maternal mortality of Bangladesh. Eclamptic seizure can effectively controlled by use of  magnesium sulphate. A prospective randomized case control study was conducted at eclampsia ward of Dhaka Medical College Hospital for one year from June 2007 to May 2008.Objective: To find out whether only 8gm of magnesium sulphate heptahydrate (Nalepsin) as a  single loading dose is sufficient to control eclamptic convulsion and also to compare the efficacy between 8gm & 10gm of MgSo4 used to control convulsion.Methodology: A random selection was done by lottery of those antepartum and intrapartum  cases who fulfill the selection criteria. Hundred patient were selected and grouped them into  case & control. 8gm Nalepsion (Magnesium sulphate heptahydrate) as a single I.V dose was  selected for case and 10gm MgSo4 (4gm I.V + 3gm I.M in each buttock) was for control  group. Different variables were compaired and results were analyzed by unpaired ‘t’ test and chi-square test (X2) by SPSS programme. Result: Statistically there was no significant difference of any finding between two groups after comparing all variables individually.Conclusion: 8gm Nalepsin intravenously as a single loading dose is sufficient to control  eclamptic convulsion and prevention of its recurrence.DOI: http://dx.doi.org/10.3329/bjog.v25i2.13743 Bangladesh J Obstet Gynaecol, 2010; Vol. 25(2) : 71-76  

2017 ◽  
Vol 34 (2) ◽  
pp. 85-91
Author(s):  
Salma Rouf ◽  
Shatil Ahmed ◽  
Ms Ashiana Afrin

Background:Intramuscular loading dose of Magnesium Sulphate could be a suitable alternative for community intervention of the management of severe Pre- Eclampsia and Eclampsia.Objective: To compare the efficacy of the loading total IM regime of injection Magnesium Sulphate (MgSO4) with the standard loading combined IV and IM regime for termination & prevention of recurrent convulsions in the treatment of Eclampsia.Methods: Total 200 patients were studied at Dhaka Medical College Hospital, Bangladesh from October 2012 to May 2013 where 100 patients were treated with loading IM regime (Case group) and 100 patients received standard loading combined IV & IM regime (Control Group). The efficacy of both regimes was measured by the rate of recurrent convulsions.Results: No significant differences was observed in both groups in terms of age (23.03±3.90 vs 23.34±4.63 years), parity (64% vs 63% primi), gestational age (36.39±3.64 vs 36.13±3.95 weeks),no of convulsions (5.28±3.21 vs 5.35±3.31 times), mean diastolic blood pressure (98.74±17.22 vs 104.25±15.43 mmHg) and Glasgow Coma Scale (e”8, 96% vs<8, 92%). No significant differences observed between the two groups in mean convulsion to treatment interval (5.16±3.71 vs 4.95±3.12 hr) and convulsion to delivery interval (13.26±8.8 vs 13.95±8.46 hr). The recurrent convulsion rate was almost same in both groups (3% vs 5%, ð2 = 0.521, P> 0.05ns). Case fatality was 2% in case group and 3% in control group (P > 0.05ns).Conclusions: Loading total IM regime of MgSO4 is found as effective as the loading combined IV and IM regime in terms of control of convulsions and prevention of recurrent fits in Eclampsia. So it could be used by the field level workers before referral.J Bangladesh Coll Phys Surg 2016; 34(2): 85-91


2010 ◽  
Vol 80 (1) ◽  
pp. 37-42 ◽  
Author(s):  
S. M. Banabilh ◽  
A. R. Samsudin ◽  
A. H. Suzina ◽  
Sidek Dinsuhaimi

Abstract Objective: To test the null hypothesis that there is no difference in facial profile shape, malocclusion class, or palatal morphology in Malay adults with and without obstructive sleep apnea (OSA). Materials and Methods: Subjects were 120 adult Malays aged 18 to 65 years (mean ± standard deviation [SD], 33.2 ± 13.31) divided into two groups of 60. Both groups underwent clinical examination and limited channel polysomnography (PSG). The mean OSA and control values were subjected to t-test and the chi square test. Results: Physical examination showed that 61.7% of the OSA patients were obese, and 41.7% of those obese patients had severe OSA. The mean body mass index (BMI) was significantly greater for the OSA group (33.2 kg/m2 ± 6.5) than for the control group (22.7 kg/m2 ± 3.5; P &lt; .001). The mean neck size and systolic blood pressure were greater for the OSA group (43.6 cm ± 6.02; 129.1 mm Hg ± 17.55) than for the control group (35.6 cm ± 3.52; 114.1 mm Hg ± 13.67; P &lt; .001). Clinical examination showed that the most frequent findings among OSA groups when compared with the control group were convex profiles (71.7%), Class II malocclusion (51.7%), and V palatal shape (53.3%), respectively; the chi square test revealed a significant difference in terms of facial profile and malocclusion class (P &lt; .05), but no significant difference in palatal shape was found. Conclusion: The null hypothesis is rejected. A convex facial profile and Class II malocclusion were significantly more common in the OSA group. The V palatal shape was a frequent finding in the OSA group.


2021 ◽  
Vol 45 (5) ◽  
pp. 312-316
Author(s):  
Mishra Neha Sanjeev ◽  
Harsimran Kaur ◽  
Sandeep Singh Mayall ◽  
Rishika ◽  
Ramakrishna Yeluri

Objective: To evaluate the effectiveness of placing a resorbable collagen barrier in impeding the extrusion of obturation material in primary molars undergoing resorption. Study design: All the 94 canals in 47 mandibular molars were allocated to 2 groups- Group ‘A’- 47 canals with collagen barrier (Test group) and Group ‘B’- 47 canals without collagen barrier (Control group) based on randomization protocol. Pulpectomy was performed and obturation of both test and control canals were radiographically assessed. Pearson’s chi – square test was applied to analyze the results. The significance level was predetermined at p &lt; 0.05. Results: Among the test group, 93.6% of the canals showed no extrusion while, 6.4% showed visible extrusion of the material outside the apex. In the control group, 83% showed no extrusion whereas 17% of the canals showed visible extrusion outside the apex. But no significant difference was noted (p&gt;0.05). Conclusion: The placement of resorbable collagen barrier in the apical third of the canal prevented the extrusion of obturating material beyond the apex in resorbing primary molars.


2018 ◽  
Vol 5 (2) ◽  
pp. 68-72 ◽  
Author(s):  
Shila Rani Das ◽  
Chinmay Biswas

Background: Medical students are in a huge pressure due to their academic syllabus. Objective: The purpose of the present study was to assess the relationship between anxiety and academic performance among private medical college.Methodology: This cross sectional study was done in private medical College Hospital, Dhaka, Bangladesh and 3rd and 4th year medical student were included. Data was   collected by using semi structured Socio-demographic questionnaire and Burn Anxiety Inventory scale and Checklist. Finally all data and results were analyzed using latest version of SPSS software. For descriptive statistics means, medians, SD and range will be calculated as required. Data will be presented in frequency table, bar, pie and scattered diagram as per need.  Statistical test chi-square test were used and p<0.05 was consider to be statistically significant.Results: A total number of 200 medical students were studied after fulfilling the inclusion and exclusion criteria. Among them 87.0% were Muslim; 98.0% were unmarried; 83.0% were in nuclear family; family member of 42.5% respondents had 4 to 6 persons; monthly income of 64.7% respondents were less than 50,000 Taka; 47.0% of the respondents’ father occupation was businessman. In 1st profession examination 68.0% in Anatomy, 73% in Physiology, 76% in Biochemistry were passed in anatomy. In 1st professional exam, students suffered from moderate to extreme anxiety were passed 78% and referred 22% as well as suffered from minimal to mild anxiety were passed 43% and referred 57% in Physiology. So there was strong association between the two variables (p<0.05).Conclusion: Three fifth of the students are suffered from moderate anxiety level and those who are suffered moderate to extreme anxiety passed more and their class attendance are good.Journal of Current and Advance Medical Research 2018;5(2):68-72


2021 ◽  
Vol 21 ◽  
pp. e226341
Author(s):  
Moses Okechukwu Azouru ◽  
Modupe Olufunmilayo Ashiwaju ◽  
Augustine Edomwonyi ◽  
Afolabi Oyapero ◽  
Bola Obisesan ◽  
...  

Treatment of dental caries in children still remains challenging due to lack of cooperation with conventional treatment modalities. Recently, the use of Silver Diamine Fluoride (SDF) has proved useful in addressing this challenge. Aim: This clinical trial aimed to evaluate the effectiveness of Silver Diamine Fluoride (SDF) in arresting caries in children in Lagos, Nigeria. Methods: This was a phase III balanced randomized controlled school based interventional study on 240 children. The study group was treated with SDF while GIC was used in the control group. Follow up visits in 2 weeks, 1 month, and 3 months were carried out to assess the treatment outcome. Inferential statistics with the use of Pearson Chi-square test and Independent Student t-test were used at 5% level of significance. Results: There was significant relationship between SDF and caries arrest in 2 weeks, 1 month and 3 months’ assessment period (p = 0.001). The control group showed continuous decline (71.7%, 54.3% and 50.9%) in restorative success from 2 weeks to 3 months respectively. The mean ± SD and Confidence Interval (CI) of arrested caries in the SDF group were 113± 1.24 and 113.1 – 113.5 respectively. In the control group the mean ± SD and CI of restorative success were 69.3±11.8 and 67.2 – 71.4. The effect size was 5.24. Conclusion: The result of the study showed that SDF was effective in arresting caries in children without any harm and there was statistically significant difference in the use of 38% SDF in arresting caries in children.


2011 ◽  
Vol 52 (1/3) ◽  
pp. 45-47
Author(s):  
Carolina Dos Santos Guimarães ◽  
Gerhilde Callou Sampaio ◽  
Élvia Barros de Almeida ◽  
Luciano Barreto Silva ◽  
Ana Paula Mourato ◽  
...  

Introduction: The present study sought to assess the effect of apical foramen cleaning in the repair of periapical lesions detected by radiography. Methods: The sample comprised 980 teeth collected from 25 February 1997 to 15 March 2005 which had been subjected to endodontic treatment and exhibited radiographically visible periapical lesions. The sample was then divided into two groups: Group I, 402 root canal treatments in which cleaning of the apical foramen had not been performed, and Group II, composed of the remaining 578 root canal treatments where the procedure had been performed. After one year, the teeth were clinically and radiographically evaluated. Results: In Group I, 360 canals (89.55%) had no evidence of periapical lesions, versus 521 (90.13%) in Group II. Partial presence of these lesions was observed in 23 canals (5.72%) in Group I versus 27 (4.67%) in Group II. No changes in images were observed in 19 (4.72%) canals in Group I and 30 in Group II. Pearson’s chi-square test showed no statistically significant difference between the Groups I and II (p = 0.732). Conclusions: These findings suggest that foramen cleaning is not a determinant of periapical lesion repair.


2019 ◽  
Vol 8 (2) ◽  
pp. 95-100
Author(s):  
Mehry Bozorgnejad ◽  
Mohammad Reza Zarei ◽  
Leila Mamashli ◽  
Fatemeh Mohaddes Ardebili

Background: Burning is one of the worst accidents that people may now experience in modern society. One of the most critical problems of burn patients is the anxiety caused by medical treatments such as burn dressing. The present study aimed to determine the effect of rhythmic breathing on the anxiety of dressing change in burn patients. Materials and Methods: This experimental clinical trial was done on 60 burn hospitalized patients in Ayatollah Mousavi educational-therapeutic hospital of Zanjan province in 2017. The sampling was performed continuously and the samples were randomly assigned to control and experimental groups (30 subjects in each group). The data collection tool included a demographic questionnaire and numerical anxiety scale. First, the demographic characteristics questionnaire was completed by the samples. Then, the rhythmic breathing was taught to the experimental group for 20 minutes until complete learning, and they were asked to perform the rhythmic breathing during dressing. Before and after dressing, anxiety was evaluated in the experimental and control groups for 3 consecutive days. After collecting data and entering them into SPSS 20, data were analyzed using descriptive statistics, chi-square test, independent and dependent t test, and Friedman test. Results: Based on the findings of the study, both groups were homogeneous in terms of age, gender, education, percentage and the degree of burn, and there was no statistically significant difference. The results of the Friedman test showed that the anxiety severity had a statistically significant difference in both control and experimental groups before and after the intervention (P<0.001). However, the severity of anxiety after the intervention further reduced in the experimental group compared to the control group, and this reduction was statistically significant in the experimental group (P<0.001). Conclusion: In general, rhythmic breathing is effective in reducing anxiety caused by a dressing change in burn patients. Thus, this method can be used to decrease the anxiety of dressing.


2021 ◽  
Vol 10 (4) ◽  
pp. 354-367
Author(s):  
Tahereh Baloochi Beydokhti ◽  

Objective: Hemodialysis is one of the most common treatment methods in kidney patients. To do this, repeated insertion of the needle into the vessel is necessary. Patients treated with hemodialysis are exposed to stress and pain caused by perforation of their arteriovenous fistula about 300 times a year. More than 1/5 of hemodialysis patients express this pain as unbearable. This study aims to evaluate the effect of acupressure at SP6 and ST36 acupoints on the pain caused by fistula needle placement in hemodialysis patients. Methods: This study is a double-blind randomized clinical trial conducted in 2016 on 90 hemodialysis patients with arteriovenous fistula in Mashhad, Iran. They were randomly divided into three groups of SP6, ST36, and control. Data were collected after obtaining a written informed consent by a demographic form and the Visual Analog Scale (VAS). Data analysis was performed in SPSS v.16 software by using Kolmogorov-Smirnov test, Kruskal-Wallis test, one-way ANOVA, paired t-test, and Chi-square test. Results: There was a statistically significant difference between VAS scores after the intervention in all three group (P<0.001). The Mean±SD VAS scores before the intervention in SP6, ST36, control groups were 54.47±18.93, 51.5±22.83, 46.6±17.73, respectively which changed to 45.63±20.53, 40.2±20.01, and 51.87±19.05 after the intervention, indicating that acupressure at SP6 and ST36 acupoints reduced pain in patients, while the pain increased in the control group. Conclusion: Acupressure at SP6 and ST36 acupoints is an effective method in relieving pain caused by the insertion of a needle into the arteriovenous fistula in hemodialysis patients.


2019 ◽  
Vol 25 (6) ◽  
pp. 460-463
Author(s):  
Gino Fellipe Santoro ◽  
Katlyn Duarte de Mello ◽  
Zair Cândido de Oliveira Netto ◽  
Gabrielle Pfutzenreuter ◽  
Julio Cesar Bassan ◽  
...  

ABSTRACT Introduction Physical performance depends on a variety of biological and mechanical properties. These different phenotypes are related through the complex interaction between the environment and the individual genetic profile. The hypothesis is that there is a hereditary component that interferes in physical fitness. ACE stands out among the genes that may influence this response. Objectives The objective of this study is to analyze the polymorphism of the ACE gene in American football athletes. Methods: At the end of the study, the sample was composed of 45 male athletes and 72 non-athletes. DNA was extracted from the jugal mucosa. ACE polymorphisms were genotyped through polymerase chain reaction and analyzed using the electrophoresis process. To compare the frequency of genotypes between athletes and the control group, we used the Chi-square test. The association between the frequencies of alleles was verified through the 2X2 contingency tables analyzed using the Chi-square test with Yates correction. The type of study was diagnostic - Investigation of a diagnostic test, level of evidence II. A p-value of ≤0.05 was considered statistically significant for all the analyses. Results The results showed a greater frequency of the D allele in American football athletes when compared with non-athletes, and a significant difference in the genotypic distribution of the athletes being composed of a higher number of the DD genotype as compared to the control group. Conclusion The study provides evidence of the allelic and genotypic influence of ACE polymorphism in amateur American football players in Brazil. Level of evidence II; Investigation of a diagnostic test.


2015 ◽  
Vol 22 (2) ◽  
pp. 173-178
Author(s):  
Mohammad Zaid Hossain ◽  
Khan Abul Kalam Azad ◽  
Pratyay Hasan ◽  
Tahmeed Hussain ◽  
Kazi Monisur Rahman ◽  
...  

Though it is long known that irregular intake of antihypertensive may cause harm, but still there is much lack of awareness among the patients in this matter. This case controlled study was done in Dhaka Medical College Hospital, Dhaka, to determine the relationship between discontinuation of antihypertensive drugs and the risk of stroke among hypertensive patients. Number of cases was 72. Control group was selected via random sampling of stroke free treated hypertensive group, similar in age to stroke cases. Sampling technique was random systematic sampling. The relationship was determined employing statistical methods including Chi-square (?2) test using computer programs, and significant association between discontinuation of antihypertensive and development of stroke in hypertensive adult patients was found ?2(1,N= 103) = 32.637, p<0.001. Odd’s ratio is 15.83. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21530 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 173-178


Sign in / Sign up

Export Citation Format

Share Document