A Study On Clinical and Laboratory Profile of Children with COVID-19 Attending A Tertiary Care Hospital in Bangladesh

Background: An outbreak of COVID-19 caused by 2019 novel coronavirus started first in Wuhan, Hubei province of China. Thereafter it spreaded to different countries of the world. Cases among children has been increasing day by day. Despite taking all measures of prevention virus spreading is uncontrolled. Objectives: To determine the clinical features and laboratory profile of children with COVID-19. Methods: This was a cross sectional study conducted in Dr. MR Khan Shishu Hospital and Institute of Child Health, Dhaka. Clinical and laboratory profile were analyzed among the children (aged 0-16 years) admitted between 1st May 2020 to November 2020 with positive RT-PCR for COVID-19. Data were analyzed by using SPSS. Results: Total 159 cases were included in the study. The most common symptom was fever (97.5%), then the second most common was cough (80.5%), other symptoms were diarrhea (28.3%), vomiting (17%), anorexia (30.8%) and weakness (30.2%). WBC count was within normal limit, leucocytosis was found in 5% cases and leucopenia in 3% cases. Few cases were reported with neutropenia and lymphopenia. Few cases were reported as thrombocytosis. ESR and CRP were high. Chest X-ray showed opacities in 62.9% cases. In most of the cases it was bilateral, few cases showed unilateral. In 37.1% cases it was normal. The disease category of all infected children remained same all through the hospital stay and no mortality was seen. Conclusion: Children with COVID-19 had distinct clinical features. Fever and cough were the most common symptoms. WBC count was found within normal limit but ESR and CRP were high. Chest radiograph showed opacities in majority cases. The outcome of COVID-19 in children was good. DS (Child) H J 2020; 36(2): 95-100

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Clinical and laboratory profile of multisystem inflammatory syndrome in children: A cross-sectional study in a tertiary care hospital, Mysuru

Indian Journal of Child Health ◽

10.32677/ijch.v8i11.3110 ◽

2021 ◽

Vol 8 (11) ◽

pp. 386-390

Author(s):

Raksha Kottakki ◽

Sudha Rudrappa ◽

Pratibha Manjunath Patagar

Keyword(s):

Tertiary Care ◽

Cross Sectional Study ◽

Medical Attention ◽

Common Symptom ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Long Term Outcome ◽

Laboratory Profile ◽

Inflammatory Syndrome

Background: Multisystem inflammatory syndrome in children (MIS-C) is considered to be a rare, yet serious complication of coronavirus disease 2019, where there is immune dysregulation related to past infection with the virus. It is an inflammatory syndrome affecting multiple systems with varied manifestations including gastrointestinal, cardiovascular, respiratory, neurological, renal, hepatobiliary, and dermatological symptoms. Aim: Current study aimed to investigate the clinical and laboratory profile of MIS-C. Materials and Methods: A cross-sectional study of 40 hospitalized children who were diagnosed as MIS-C and studied over a 12-month period from June 2020 to May 2021 at Cheluvamba Hospital in a tertiary care center attached to Mysore Medical College and Research Institute Mysuru, Karnataka. Results: Out of the 40 children studied, all fulfilled the diagnostic criteria of MIS-C. The most common symptom was fever (100%), followed by gastrointestinal symptoms (90%). The next most common system involved in our study was cardiovascular system (52.5%). The most common laboratory findings included elevated inflammatory markers (100%). Furthermore, there was high incidence of hematological alterations, in the form of anemia (62.5%), thrombocytopenia (57.5%), and neutrophilia (27.5%). About 33.3% cases had echocardiography abnormalities. All patients received intravenous methylprednisolone and intravenous immunoglobulin. There were six deaths (15%) in our study and the remaining cases had good immediate outcome. Conclusion: Early recognition and prompt medical attention are necessary for a favorable outcome in MIS-C. However, there is scarcity of data regarding its long-term outcome.

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Clinical profile and changes in laboratory parameters among dengue patients at tertiary care hospital: an observational study

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20191857 ◽

2019 ◽

Vol 6 (5) ◽

pp. 2276

Author(s):

Pankaj Ashok Pande ◽

Amit Jagdish Jogdande

Keyword(s):

Observational Study ◽

Clinical Features ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Lifestyle Changes ◽

Common Symptom ◽

Care Hospital ◽

Rapid Urbanization ◽

Dengue Patient ◽

Laboratory Profile

Background: Globally the incidence of dengue has increased in the past three decades. It is predominantly found in the urban and semi-urban area however now it is spreading in rural areas also. In India the incidence of dengue has increased due to rapid urbanization, lifestyle changes and improper water storage practices. Hence this study was planned to study the clinical and laboratory profile of dengue patient as the number of dengue patients is on rise every year and there is varied presentation of clinical features in different parts of India.Methods: This observational study was carried out in tertiary care hospital. Confirmed cases of Dengue were included in the study. There cases were observed seven days. During this period their clinical and biochemical profile was recorded in pre structured and pre tested proforma. Data was compiled and analyzed by MS-Office (Excel) and SPSS-21.Results: In this study total 129 patients were enrolled. Out of total 91 were males and 38 were females. Laboratory profile of dengue patients suggested steep decline in total leucocytes count and platelet during first five days but started to increase by seventh day but platelets have not reached to its original normal value while TLC reverted to normal range. Fever and headache were most common symptom in our study.Conclusions: Clinical and laboratory profile of dengue patient changes with every new epidemic and different region in India. Clinical features like organomegaly are more common in paediatrics age group than adults.

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A study about urinary tract infection among patients attending tertiary care hospital

International Surgery Journal ◽

10.18203/2349-2902.isj20173399 ◽

2017 ◽

Vol 4 (8) ◽

pp. 2620 ◽

Cited By ~ 2

Author(s):

Arunachalam U. ◽

Ponmudi C. ◽

Prashant V. Solanke ◽

Deepam Das ◽

Vignesh N. ◽

...

Keyword(s):

Tertiary Care ◽

Cross Sectional Study ◽

Study Group ◽

Common Symptom ◽

Care Hospital ◽

Medical Sciences ◽

Cross Sectional ◽

Recurrent Uti ◽

Study Population

Background: UTI is a second most common type of infection, accounting for nearly 25% of all infections. Lower UTIs are much more common in women than in men, particularly in the under 50’s. UTI are common among patients with type 2 diabetes mellitus. Recurrent UTI is a common phenomenon that is observed among women who have experienced uncomplicated UTIs. Usually 5-10 days of antibiotic therapy is done for treating UTI. Successful antimicrobial therapy will usually ameliorate symptoms promptly, with substantial clinical improvement in 48 to 72 hours. The objective is to find out the knowledge and practice about UTI among UTI sufferers.Methods: The study design is cross sectional study. The study period is from July 2016 to February 2017. The study place is Sree Mookambika Institute of Medical Sciences. The sample size is (4PQ/d²) = 31. Systematic random sampling techniques are used. Institutional ethical committee clearance was obtained.Results: In the study 90.3% are women. In the study 32.3% had a recurrent UTI. In the study population about 51.7% take adequate or plenty of water. In this study 35.5% have poor knowledge, 42% have moderate knowledge and 19.5% have a good knowledge about UTI.Conclusions: From the study, it is learnt that UTI is common among the women and recurrence is the most common thing among the asymptomatic UTI group. The common symptom experienced by the study group is dysuria and frequency and most in the study group used to take less than recommended amount of water daily. They believe drinking plenty of water and cleanliness can prevent the UTI. The knowledge about UTI among the group is fairly good.

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Knowledge, attitude and practice regarding tuberculosis among the patients attending a tertiary care hospital in Maharashtra, India: a cross sectional study

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20191143 ◽

2019 ◽

Vol 6 (2) ◽

pp. 371

Author(s):

Nilesh S. Sonawane ◽

Chaitanya R. Patil

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Cross Sectional Study ◽

Common Symptom ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Female Ratio ◽

Attitude And Practice ◽

Knowledge Attitude And Practice

Background: Tuberculosis is major public health problem especially in the low and middle income countries like India. We conducted a study to assess the knowledge, attitude and practice related to tuberculosis among the patients attending our tertiary care institute.Methods: A cross sectional study was conducted in a tertiary care hospital on the patients attending OPD of tertiary care hospital in Maharashtra. The patients with debilitating illness or bed bound patients and those diagnosed and cured of tuberculosis or were on treatment of tuberculosis were excluded from the study. A pretested and designed questionnaire was used to assess the knowledge, attitude and practice about the cause, clinical features and treatment of tuberculosis.Results: The mean age of the study subjects was 43.34±11.23 years with male: female ratio of 1.45. About 16.67% of the subjects stated that cause of TB is bacteria, 51.33% reported that cough was the most common symptom, 58.67% believed that it spreads from person to person and among the people who said it spreads 58.67% said that it can be preventable.Conclusions: About 1/5th of the study subjects expressed the cause of TB is bacteria or germs, and more than ½ believed that TB spreads from person to person. About 2/3rd of the patients felt that TB was a very serious disease; more than ½ of them expressed fear if they were diagnosed with TB but more than ½ of them also expressed rejection if they have a TB patient as a closed one.

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Clinico-demographic profile of deceased patients with coronavirus disease in a tertiary care centre of central India

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20211777 ◽

2021 ◽

Vol 8 (5) ◽

pp. 2474

Author(s):

Rupali A. Patle ◽

Ashok R. Jadhao ◽

Priya B. Dhengre ◽

Manjusha A. Dhoble

Keyword(s):

Clinical Characteristics ◽

Tertiary Care ◽

Case Fatality ◽

Central India ◽

Cross Sectional Study ◽

Common Symptom ◽

Care Hospital ◽

Tertiary Care Centre ◽

Cross Sectional ◽

The Difference

Background: The covid pandemic started from Hubei, Wuhan in December 2020 then covered many other countries including India. Understanding the demographic and clinical characteristics of deceased COVID-19 patients could inform public health interventions focusing on preventing mortality due to COVID-19. The present study was done with the objective of studying the socio-demographic and clinical profile of deceased patients with coronavirus disease.Methods: This is a hospital based cross-sectional study on 1190 deceased patients of coronavirus disease in a tertiary care hospital of central India which is a dedicated covid hospital from 11 March 2020 to 28 February 2021. Socio-demographic and clinical characteristics of deceased patients were recorded.Results: Overall case fatality rate was 13.24%. Maximum number of deaths occurred in the month of August 2020 and September 2020 were 372 (31.26%) and 477 (40.08%). It was higher in the males 791 (66.47%) as compared to females 399 (33.53%), but the difference was not significant. The most common symptom was fever on hospitalization 924 (77.65%), followed by generalized weakness 771 (64.79%). 352 (29.58%) patients died within 24 hours of the admission to hospital. Hypertension and type 2 diabetes mellitus were the most prevalent morbidity in 557 (46.80%) and 357 (30.00%). It was found that 232 (19.50%) deceased patients had oxygen saturation less than 50% on admission.Conclusions: Higher age and presence of co-morbidities at the time of admission were significantly associated with mortality.

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Hospital Based Prevalence of SARS-CoV-2 and Clinico-Demographic Profile of COVID-19 Patients: A Study from a Tertiary Care Hospital of North India

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i1430979 ◽

2021 ◽

pp. 126-136

Author(s):

Anjum Farhana ◽

Shoaib Khan ◽

Reyaz Khan ◽

Umara Amin

Keyword(s):

Severe Disease ◽

Tertiary Care ◽

Cross Sectional Study ◽

North India ◽

Common Symptom ◽

Care Hospital ◽

Cross Sectional ◽

Medical College ◽

History Of ◽

One Year

Aims: To find out the prevalence, predominant risk factors and various clinico-demographic variables among patients infected with SARS-CoV-2 during the first year of the pandemic. Study Design: Hospital based, cross sectional study. Place and Duration of Study: Postgraduate department of Microbiology, Government Medical College, Srinagar, and associated hospitals, between March 2020 and March 2021. Methodology: Individuals with acute respiratory infection (ILI and SARI), high risk contacts and asymptomatic close contacts of COVID-19 positive patients, hospitalized patients dated for surgeries, pregnant women near expected date of deliveries, travellers were screened. A confirmed case of Covid-19 was defined as a positive result on real-time RT-PCR assay of nasopharyngeal and or Oropharyngeal swab specimens. A total of 2,17,665 samples were collected and processed over a period of one year. Results: Out of 2,17,665 samples, 61.3% were males and 38.7% were females, overall mean age was 34.3 years. 24,009 (11%) tested positive for SARS-CoV-2 infection, among them 63.5% were males while 36.5% were females, the mean age observed was 35.3 years. Highest positivity was observed in the age group of 30 – 39 years (22%), followed by 20 -29 years (20.4%), 12 (0.1%). Among positive cases, 19.4% had a history of contact with a lab confirmed case of SARS-CoV-2, 4.3% were HCW’s and 2.6% were pregnant females. 929 (3.9%) patients who tested positive had presented with SARI. Fever was the most common symptom (62%), followed by cough (41%) and fatigue was reported by 37% patients. Comorbidities were present in 23.2% patients, of which Hypertension 10.8% was the most common, followed by COPD 4.9% and Diabetes mellitus 4%. Conclusion: As evident from our study, COVID-19 has a high positivity (11%) in our region, with males twice more likely susceptible than females. High percentages (62%) of people were symptomatic at presentation, while severe disease was seen in only 3.9% patients. Early aggressive testing is essential to decrease the morbidity and mortality rates associated with COVID-19.

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How safe is Covishield (ChAdOx1nCoV-19) vaccine? Experience from a tertiary care hospital in South India

10.1101/2021.03.16.21253744 ◽

2021 ◽

Author(s):

Leeberk Raja Inbaraj ◽

Carolin Elizabeth George ◽

Nirupama Navamani Franklyn

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Real Life ◽

Female Gender ◽

Cross Sectional Study ◽

Self Report ◽

Vaccine Hesitancy ◽

Common Symptom ◽

Care Hospital ◽

Cross Sectional

AbstractBackgroundCOVID vaccine has been recently rolled out for Health care workers in India. Though vaccine trials and data are available, people, including HCWs, need more real-life data from their contexts to get over the vaccine hesitancy. We aimed to determine the incidence of Adverse Event Following Immunisation (AEFI) among HCWs after their first dose of ChAdOx1nCoV-19 vaccineMethodsWe conducted a cross-sectional study among 218 staff of a tertiary care hospital. We circulated a google form with informed consent on the hospital WhatsApp platform and asked them to self-report their vaccination experience.ResultsTwo thirds (69.7% (152/218), 95% CI: 63.1-75.7) had minor AEFI, and none had severe AEFI. Body ache (46.8% (102/218), 95% CI :40 – 53.6) was the most common symptom followed by headache (30.3% (66/218), 95% CI :24.2 – 36.8) and fever (22% 948/218), 95% CI :16.7 – 28.1). Most of them (39.4% (87/218) 95% CI:32.9 – 46.2) experienced symptoms within 4-24 hours after taking the vaccine while 22.3% (49/218) (95% CI: 17.1 – 28.6) experienced it after a day. Majority of the HCWs (78.9% (172/218), 95% CI: 72.8 – 84.1) were anxious before the vaccination. Younger age group and female gender were significantly associated with AEFI compared to their counterparts.ConclusionHCWs experienced minor, self-limiting AEFI with the first dose of ChAdOx1nCoV-19. The hospital reported no serious AEFI following the vaccination

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Clinical profile of Dengue fever in an urban tertiary care hospital in South India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20192086 ◽

2019 ◽

Vol 6 (3) ◽

pp. 618

Author(s):

Dhivya P. ◽

Monica A. ◽

Jayaramachandran S.

Keyword(s):

Dengue Fever ◽

Clinical Features ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Viral Disease ◽

Cross Sectional Study ◽

Care Hospital ◽

Cross Sectional ◽

The World ◽

Study Population

Background: Dengue is among the most common flavivirus infections in the world. Today dengue ranks as the most important mosquito- borne viral disease in the world. Current estimates report that, at least 112 countries are endemic for Dengue and about 40% of the world populations (2.5-3 billion people) are at risk in tropics and subtropics. Annually 100 million cases of dengue fever and half a million cases of DHF occur worldwide. The clinical features are noted to be different in varying demographics of the world outlining the importance of bringing out data from different parts of the world, so clinicians are better equipped to anticipate the problems associated with clinical dengue.Methods: The study was conducted over a period of 2 years at a tertiary care hospital in urban Bengaluru, India. A cross sectional study of a total of 250 patients was done. They were diagnosed to be positive for dengue serology (NS1 or IgM) before including them in the study. Clinical features, haematological, biochemical and radiological parameters were assessed.Results: Out of 250 patients with dengue fever, the most common symptoms were fever (100%), headache (94.4%) and myalgia (97.2%). Bleeding manifestations were noted in 11.6% of the patients. Bradycardia was noted in 14.8% of the study population. Leukopenia was noted in 36% of the study population. Increased SGOT was seen in 59.6% and increased SGPT in 52.8% of the 250 subjects. The clinical outcome of the 250 patients of dengue fever was classical dengue fever in 86.8%, DHF in 11.6%, DSS in 0.8% and death in 0.8%.Conclusions: All patients with dengue fever present with fever. Other common features noted were headache, myalgia. Bleeding manifestations are to be looked out for. Rare but important features that a clinician must be vigilant to look for are bradycardia and leucopenia.

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Prevalence and pattern of self-medication among urban population Chidambaram: a cross-sectional study

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20195842 ◽

2019 ◽

Vol 7 (1) ◽

pp. 132

Author(s):

R. Gowthaman ◽

A. Viknesh Ambayiram

Keyword(s):

Tamil Nadu ◽

Tertiary Care ◽

Cross Sectional Study ◽

Common Symptom ◽

Care Hospital ◽

Sectional Study ◽

Self Medication ◽

Cross Sectional ◽

Field Practice ◽

Study Participants

Background: Self-medication as the selection and use of medicines by the individuals to treat self-recognised illness or symptoms. Self-medication is recognised as a part of self-care. The objectives of this study was to find out the prevalence of self-medication in an urban Chidambaram, Tamil Nadu, to find out the pattern of self-medication with regard to its practice and to find out the reasons favoring the practice of self-medication.Methods: The cross-sectional study was carried out in the month of September 2018 in a randomly selected urban field practice area of a tertiary care hospital. The sample size was calculated to be 360. Data was collected from all the houses in the selected field practice area. The data collected was entered into Microsoft excel spread sheet 2018 and analysis was done using SPSS version 21.Results: Self-medication was practiced by 195 (48.75%) of the households and 215 (18.6%) of the study participants. 42.1% reported pharmacist as source of knowledge. Most common symptom/sign for which self-medication was practiced was fever (42%). Most commonly (57.9%) used self-medicament was non-steroidal anti-inflammatory agents. Antibiotics were used by 15.4% as self- medicament. Among the 195 households practising self-medication, 65 (33.3%) reported that accessibility to pharmacy was more than that of clinic as reason for practicing self-medication.Conclusions: The usage of antibiotics as self-medicament and decreased awareness regarding the side effects of self-medicaments indicated decreased practice of responsible self-medication in the study area. More studies have to be conducted regarding the awareness, barriers and facilitators for practicing responsible self-medication.

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