scholarly journals Causes, Management and Immediate Complications of Management of Neonatal Jaundice ? A Hospital-Based Study

2015 ◽  
Vol 5 (2) ◽  
pp. 104-109 ◽  
Author(s):  
Mahmud Hossain ◽  
Momotaj Begum ◽  
Shafi Ahmed ◽  
Md Nurul Absar

Background: Jaundice is very common in the neonatal period of life. Although it is not a major cause of mortality, it is an important cause of morbidity. So, assessment of the causes and risk factors of neonatal jaundice is very important.Objectives: The objectives of the study were to find out the causes of jaundice, its clinical features, evaluation of the outcome of current management strategy and complications encountered by the participating subjects following treatment.Materials and Methods: This prospective study was conducted in the Neonatal Unit of Rangpur Medical College Hospital (RpMCH) during July to December 2006. A total of 100 neonates having jaundice on admission or who developed jaundice following admission were included in the study. A number of investigations were done for the purpose of assessment of neonates and their icteric condition. The test statistics used to analyse the data were descriptive statistics, Chi-square (?2) and correlation tests.Results: In the present study the median age of the jaundiced newborns on admission was 5 days, while the median age of appearance of jaundice was 3.5 days. Most of the newborns exhibited jaundice 24 hours after birth and peaked by 3–4 days. Majority of the subjects (77%) had pathological jaundice and only 23% had physiological jaundice. This study shows septicemia was in 28% cases followed by asphyxia (20%), prematurity (18%), Rh incompatibility (15%), IUGR (11%) etc. Half of the newborns (51%) had serum bilirubin (indirect) >10 mg/dL. Gestational age and serum bilirubin was found to exhibit a negative correlation. Preterm babies also tend to develop severe to very severe jaundice more than their term counterparts (p<0.001). Birth weight was also found to bear a negative correlation with serum bilirubin. Low birth weight (LBW) babies also had a significantly higher tendency to develop severe to very severe jaundice (p<0.001). Of the 77 patients who were treated, about 64% received phototherapy, 61% received antibiotics and very few (5.2%) received exchange transfusion. Majority of the patients developed some sorts of complications. The predominant complications of phototherapy were irritability (40.8%) followed by skin rashes (26.5%), loose motion (20.4%) and dehydration (16.3%). Very few newborns (4%) had hyperthermia. All four babies who received exchange transfusion suffered from hypovolaemia, one developed hypoglycaemia and one exhibited anaemia.Conclusion: Neonatal jaundice is a leading cause of hospitalisation in the first few weeks of life throughout the world. Though management of unconjugated hyperbilirubinaemia in newborns has undergone changes based on emerging evidences, phototherapy and exchange blood transfusion are still the most commonly used effective modalities for lowering serum bilirubin level.J Enam Med Col 2015; 5(2): 104-109

PEDIATRICS ◽  
1970 ◽  
Vol 45 (6) ◽  
pp. 918-925
Author(s):  
Bruce D. Ackerman ◽  
Geraldine Y. Dyer ◽  
Mary M. Leydorf

Serum bilirubin levels above 15 mg/100 ml occurred in 7 of 54 infants with a birth weight of less than 1,500 gm. Definite or probable kernicterus occurred in five of these seven infants. The maximum level of indirect serum bilirubin in the five infants with kernicterus varied from 18.5 to 20.4 mg/100 ml in three infants and from 22.2 to 23.2 mg/100 ml in two. Exchange transfusions were performed in four of the five infants at levels of 18 to 22 mg/100 ml but were ineffective in preventing kernicterus. Skin hemorrhage appeared to be one of the etiologic factors causing the hyperbilirubinemia in the five infants with kernicterus. Exchange transfusion must be performed at levels of indirect bilirubin below 20 mg/100 ml if death or neurologic damage are to be prevented in the small, critically ill premature infant.


2000 ◽  
Vol 32 (4) ◽  
pp. 487-493 ◽  
Author(s):  
FARID UDDIN AHMED ◽  
ENAMUL KARIM ◽  
SYEDA NURJAHAN BHUIYAN

In Bangladesh, like other developing countries, most births occur at home or in the community, so logistic problems and taboos prevent the weighing of every newborn child. This study was performed to see whether other simpler measurements could be substituted for weight to identify neonates of low birth weight. A total of 1676 live births at the Chittagong Medical College Hospital constituted the study sample, and this showed a high correlation between mid-arm circumference and birth weight (r=0.792, p<0·000). A mid-arm circumference of <9·0 cm had the best sensitivity and specificity for identifying newborns with a birth weight of less than 2500 g. These neonates were followed up to record neonatal deaths. Neonatal mortality showed an inverse relation with mid-arm circumference. A mid-arm circumference of <9·0 cm and a birth weight of <2500 g were equally useful in predicting neonatal outcome. Mid-arm circumference is a simple, quick and reliable indicator for predicting low birth weight and neonatal outcome, and can be easily measured by medical practitioners and traditional birth attendants (TBAs) in the community of developing countries like Bangladesh.


Author(s):  
M. Sujatha Alagesan ◽  
M. Meena

Background: The incidences and indications of caesarean sections between the primary caesarean multies and caesarean primies were comparable in respect of their demographical and clinical variables of mothers and their foetal outcomes. Aim and objective of the study was to analyze the incidences and indications of primary caesarean multies and caesarean primies. To compare the incidences and indications of mothers between the primary caesarean multies and caesarean primies. To compare the demographic and clinical profiles of the mothers and babies.Methods: During January to June 2016 total of 3583 deliveries were conducted in Tiruneleli Medical College Hospital, Tamil Nadu, India. Among them 89 and 1168 were primary caesarean multies and caesarean primies respectively. They had been compared according to the objectives.Results: The caesarean incidences were 62.5% among the primies and 4.8% among the multies as Primary. The primary caesarean incidences among the multies were statistically significantly lesser in the 15-24 ages than the primi (P<0.05). 25-29 age bracket the incidences were not differed significantly (P>0.05). After 30 years of age, the incidences were statistically significantly increased among the multies (P<0.05). The birth weight of babies did not show any statistically significant indications between the two groups (P>0.05). The indications of Foetal distress, Severe Oligo hydration and others did not show any statistically significantly difference between the groups (P>0.05). Mal presentation and Ante Partum hemorrhage were significantly more among the multies than primies (p<0.05) and Failed indication and CPD were the significantly lesser indication than the primies (P<0.05).Conclusions: Without reducing the caesarean section rate in primi we cannot bring down the overall caesarean rate of delivery.


2018 ◽  
Vol 42 (2) ◽  
pp. 62-66
Author(s):  
MA Rouf ◽  
Md Khairuzzaman ◽  
Nur E Nazni Ferdous ◽  
Md Golam Mowla

Background: Phototherapy is crucially an important aspect for the management of most neonatal jaundice. Neonates are prone to develop bilirubin encephalopathy (kernicterus). LED phototherapy is a new option of managing neonatal jaundice. The objective of this study is to compare the efficacy and safety of LEDs with fluorescent phototherapy in the treatment of indirect hyperbilirubinemia.Method: The study was Experimental research design, prospective study. The Study was conducted at Neonatal unit of Shaheed Suhrawardy Medical College Hospital, Dhaka. Total sample size of the study was one hundred neonates. Fifty for conventional phototherapy and fifty for LED phototherapy. Purposive sampling method was used for the study. The data collection tool of the study was pretested structured questionnaire. The modes of presentation, the clinical examination and investigation findings at admission and during daily follow up were recorded for individual patient.Result: The rate of fall of S. bilirubin was more in those neonates who have had LED phototherapy. As a result, duration of phototherapy as well as hospital stay was less in LED group. Furthermore, higher number of neonates developed rashes in LED group than in conventional group with statistically significant difference. Of course, variables regarding other adverse events did not show any statistically significant difference between two groups.Conclusion: Management of neonatal jaundice may be more effective in LED phototherapy than conventional phototherapy. LED device require shorter duration of phototherapy, thus, shorter hospital stay.Bangladesh J Child Health 2018; VOL 42 (2) :62-66


2018 ◽  
Vol 5 (2) ◽  
pp. 68-72 ◽  
Author(s):  
Shila Rani Das ◽  
Chinmay Biswas

Background: Medical students are in a huge pressure due to their academic syllabus. Objective: The purpose of the present study was to assess the relationship between anxiety and academic performance among private medical college.Methodology: This cross sectional study was done in private medical College Hospital, Dhaka, Bangladesh and 3rd and 4th year medical student were included. Data was   collected by using semi structured Socio-demographic questionnaire and Burn Anxiety Inventory scale and Checklist. Finally all data and results were analyzed using latest version of SPSS software. For descriptive statistics means, medians, SD and range will be calculated as required. Data will be presented in frequency table, bar, pie and scattered diagram as per need.  Statistical test chi-square test were used and p<0.05 was consider to be statistically significant.Results: A total number of 200 medical students were studied after fulfilling the inclusion and exclusion criteria. Among them 87.0% were Muslim; 98.0% were unmarried; 83.0% were in nuclear family; family member of 42.5% respondents had 4 to 6 persons; monthly income of 64.7% respondents were less than 50,000 Taka; 47.0% of the respondents’ father occupation was businessman. In 1st profession examination 68.0% in Anatomy, 73% in Physiology, 76% in Biochemistry were passed in anatomy. In 1st professional exam, students suffered from moderate to extreme anxiety were passed 78% and referred 22% as well as suffered from minimal to mild anxiety were passed 43% and referred 57% in Physiology. So there was strong association between the two variables (p<0.05).Conclusion: Three fifth of the students are suffered from moderate anxiety level and those who are suffered moderate to extreme anxiety passed more and their class attendance are good.Journal of Current and Advance Medical Research 2018;5(2):68-72


2020 ◽  
Vol 32 (2) ◽  
pp. 79-83
Author(s):  
Shiffin Rijvi ◽  
Sharmin Abbasi ◽  
Farhana Dewan ◽  
Sehereen Farhad Siddiqua ◽  
Anuradha Karmakar

Background: Perinatal health is influenced by maternal weight gain. Increase in obesity in population and excess weight during pregnancy may be different complications including large for gestational age fetus. As a result cesarean delivery has increased in prevalence. Maternal weight gain during the 2nd and 3rd trimesters is an important determinant of fetal growth Objective: To determine the relationship between maternal weight gain and birth weight of baby at term. Methodology : A cross sectional study was carried among 50 pregnant women at term in the Department of Obstetrics and Gynaecology, Shaheed Suhrawardy Medical College and Hospital and Anwer Khan Modern Medical College Hospital during the period of January 2013 to July 2013. Data were collected in pre-designed data collection sheet. Results: This study found maximum (36%) were age group 21-25 years followed by 28% were ≤20 years, 24% were between 26-30 years, 8% were between 31-35 years and only 4% were of 36-40 years. The average age was 25 years. Among these 50 pregnant women, 2 cases (4%) had BMI < 18.5, 15 cases (30%) had a BMI 18.5-24.9, 19 cases (38%) had a BMI 25-29.9 and 14 cases (28%) had a BMI ≥30. The mean birth weight was 2.77±0.33. kg. Mean weight gain was 10.72±3.72 Kg. Conclusion: This study showed that reasonable maternal weight gain significantly increased birth weight of the baby at term. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(2) : 79-83


2015 ◽  
Vol 22 (2) ◽  
pp. 173-178
Author(s):  
Mohammad Zaid Hossain ◽  
Khan Abul Kalam Azad ◽  
Pratyay Hasan ◽  
Tahmeed Hussain ◽  
Kazi Monisur Rahman ◽  
...  

Though it is long known that irregular intake of antihypertensive may cause harm, but still there is much lack of awareness among the patients in this matter. This case controlled study was done in Dhaka Medical College Hospital, Dhaka, to determine the relationship between discontinuation of antihypertensive drugs and the risk of stroke among hypertensive patients. Number of cases was 72. Control group was selected via random sampling of stroke free treated hypertensive group, similar in age to stroke cases. Sampling technique was random systematic sampling. The relationship was determined employing statistical methods including Chi-square (?2) test using computer programs, and significant association between discontinuation of antihypertensive and development of stroke in hypertensive adult patients was found ?2(1,N= 103) = 32.637, p<0.001. Odd’s ratio is 15.83. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21530 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 173-178


2015 ◽  
Vol 6 (2) ◽  
pp. 70-72
Author(s):  
Maksudur Rahman ◽  
Probir Kumar Sarkar ◽  
Tahera Nazrin ◽  
Khanta Chowdhury ◽  
Rawshan Akter Jahan ◽  
...  

Objective : To identify etiology of neonatal hyperbilirubinaemia requiring Exchange Transfusion (ET) and to see the complications of ET and its outcomes.Methods : This prospective study was done in a tertiary hospital. Total 39 admitted newborn babies with hyperbilirubinaemia who required exchange transfusion were enrolled and all information regarding etiology of jaundice, laboratory investigations, complications and outcomes of cases were documented and analyzed.Results : During one year of study period ET was done in 39 neonates. Among them 16 (41%) cases were male and 23(59%) were female. Fifteen (38%) babies were preterm and 24(62%) babies were term. Fifteen (38%) babies were preterm low birth weight (PLBW) with or without septicaemia as comorbidity. Twelve (31%) cases had only hyperbilirubinaemia. Rh-incompitability was seen in 17 (44%), ABO incompitability in 15(38%) cases and unknown cause in 7(18%) neonates. Common complications seen were hypoglycaemia in 7(18%) and thrombocytopenia in 6(15%) neonates. Two (5%) neonates who died had comorbidity.Conclusion : Exchange transfusion is required mostly in Rh incompitability and common complications of ET were hypoglycaemia and thrombocytopenia.Northern International Medical College Journal Vol.6(2) 2015: 70-72


Author(s):  
Pradip Kumar Bhue ◽  
Himansu Prasad Acharya ◽  
Subrat Kumar Pradhan ◽  
Pratima Biswal ◽  
Amit Pritam Swain ◽  
...  

Background: World Health Organization has defined low birth weight (LBW) as birth weight less than 2,500 grams. Giving birth to a LBW infant is influenced by several factors. Objective of the study was to measure the proportion of low birth weight babies delivered in V.S.S medical college and hospital, Burla and its association with socio-demographic factors.Methods: Hospital based cross -sectional study comprising of 1030 postnatal women who delivered single live baby in V.S.S Medical College and Hospital, Burla. Selection of study participants was done by systematic random sampling in the study period October 2012 to September 2014. Chi-square test was used to measure association between LBW and socio-demographic factors.Results: The proportion of LBW was found to be 27.76%. The proportion of LBW babies was high and significant in extremes of age i.e. teenage (44.19%) and 30 years and above age group (39.56%) and Muslim mothers (36.36%), illiterate mothers (53.52 %), manual labourer (67.14%), socioeconomic class IV and V (32.98%), consanguinity history (60.58%), smoky fuel (30.02%), consumption of tobacco (49.11%).Conclusions: The proportion of LBW (27.76%) was found to be higher than national average (21.5%).


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