scholarly journals Platelet Phaeresis for Component Therapy in Dhaka Medical College- A Study of 26 Procedures

1970 ◽  
Vol 8 (2) ◽  
pp. 53-56
Author(s):  
Laila Arjumand Banu ◽  
Kazi Nowshad Hossain
Keyword(s):  
Platelet Count ◽  
Blood Transfusion ◽  
Dengue Shock Syndrome ◽  
Caesarian Section ◽  
Ovarian Tumour ◽  
College Hospital ◽  
Medical College ◽  
Single Donor ◽  
Different Types ◽  
Low Platelet Count

Platelet separation by aphaeresis machine from single donor was started in Blood Transfusion Department of Dhaka Medical College Hospital, from 10th April 2002. This study includes 26 procedures done in this dept. from the period of 10th April 2002 to 4th June 2003. Observation showed that demand of platelet came from different wards for different types of diseases such as , for Dengue- 8 cases, for Aplastic anaemia-2 cases, for Ovarian tumour-2 cases, for Caesarian section post operative DIC -2 cases, for AML with low platelet count -3 cases, for IUD with low platelet count -1 case, for Blood cancer -1 case , for NHL chemotherapy induced thrombocytopenia- 1 case , for Dengue Shock Syndrome - 1 case , 5 units donated in Shishu Hospital . Platelet was supplied according to group specific of the patient. Such as, 12 cases were O +ve, 10 cases were B +ve ,3 cases were A+ve and 1 case was AB+ve.      DOI = 10.3329/jom.v8i2.1407 J MEDICINE 2007; 8 : 53-56

scholarly journals A study of thrombocytopenia in pregnancy

2020 ◽  
Vol 9 (3) ◽  
pp. 1115
Author(s):  
Komal Modi ◽  
Jaydeep Chaudhari ◽  
Disha Vaja
Keyword(s):  
Platelet Count ◽  
Mode Of Delivery ◽  
Antenatal Clinic ◽  
Fetal Outcome ◽  
Medical College ◽  
Single Donor ◽  
Gestational Thrombocytopenia ◽  
Low Platelet Count ◽  
Labour Room ◽  
Donor Plasma

Background: Thrombocytopenia is defined as low platelet count and if it is present during pregnancy can jeopardize the maternal and fetal outcome. Thrombocytopenia occurs in 6-15% of pregnancies. Causes of thrombocytopenia include gestational, idiopathic thrombocytopenia, preeclampsia, HELLP, DIC, malignancy and marrow failure. Aim of this study was to find out the common causes of thrombocytopenia in this hospital and management being used.Methods: Data was collected form those women who came to the antenatal clinic (booked) and labour room (unbooked) in the department of obstetrics and gynecology, GMERS Medical College and Hospital, Sola, Ahmedabad. Data of a total of 75 pregnant women were collected during the period of July 2018 to June 2019.Results: There were 66.67% cases of gestational thrombocytopenia, 13.33% related to preeclampsia, 8% in Eclamptic patients, 2.67% in HELLP and DIC, 6.67 in ITP, and lastly 2.67% in dengue cases. There were number of associated complication whether directly related (PPH) or part of the disorder. PPH was observed in 22.67% which is maximum among all complications. Other complications were part of major associated illness i.e. liver failure (6.67%), renal failure (5.3%), DIC (5.3%) and HELLP (8%).Conclusions: Mode of delivery was not influenced by platelet count, but for obstetric indications. Management of patients was as per the diagnosis. Single donor plasma is preferable to random donor plasma. PPH was the commonest complication and we should be wary of that.

scholarly journals A clinical study of spectrum of low platelet count to establish etiology, diagnosis, complications and prognosis in newborns admitted in Al-Ameen medical college hospital NICU, Bijapur, Karnataka, India

2020 ◽  
Vol 7 (7) ◽  
pp. 1451
Author(s):  
Rizwan U. Zama ◽  
Naushad Ali N. Malagi ◽  
A. N. Thobbi ◽  
Salim A. Dhundasi
Keyword(s):  
Platelet Count ◽  
Capsular Polysaccharide ◽  
Common Finding ◽  
Severe Thrombocytopenia ◽  
College Hospital ◽  
Platelet Counts ◽  
Medical College ◽  
Red Cell Indices ◽  
Low Platelet Count ◽  
Complete Blood Counts

Background: In the newborn low platelet count is a common finding in both preterm and term newborn. It has been estimated that as many as 22% of all new borns admitted to NICU develop low platelet counts. A platelet count of less than 150,000/mL is defined as thrombocytopenia irrespective of the age of the individual.Methods: All the neonates underwent necessary blood investigations like Complete blood counts, (including platelet counts, HB estimation, Red cell indices and PCV), Capsular Polysaccharide - reactive protein. (CRP), Peripheral Smear study, Blood culture, BT, CT, PT, aPPT, Anti-platelet Antibodies.Results: The prevalence of thrombocytopenia in our study was 28%. The proportion of severe thrombocytopenia among the neonatal thrombocytopenia, 11.2% in our study.Conclusions: It can be concluded that thrombocytopenia is very much common in among our NICU admissions. Septicemia is its most important and most common cause.

Effect of Donor Variables on Platelet Yield Among Donor Undergoing Plateletpheresis at Transfusion Medicine Department, Dhaka Medical College Hospital (Experience of 350 Procedures)

2021 ◽  
Vol 28 (2) ◽  
pp. 179-183
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Kashfia Islam ◽  
ABM Al Mamun
Keyword(s):  
Platelet Count ◽  
Statistical Significance ◽  
Haemoglobin Concentration ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Platelet Recovery ◽  
Medicine Department ◽  
Medical College ◽  
Donor Factors

Background: The platelet transfusions help in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelet transfusion plays an important role in the treatment of haematological, oncological, surgical, and transplant patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. Over the last decade there has been a trend towards the use of SDPs rather than pooled random donor platelets in thrombocytopenic patients. Optimization of platelet yield is an emerging issue to identify factors which may help in selecting donors to obtain higher platelet yields in shorter time and consequently better clinical outcome. Objective: The quality of single donor platelets (SDP) in terms of yield influences the platelet recovery in the recipient. The aim was to identify the SDP donor factors that influence platelet yield. Methods: The study was undertaken at transfusion medicine department, DMCH from 1st January 2017 to 31st December 2017. The study included 350 plateletpheresis procedures. All procedures were performed according to manufacturer’s manual and standard operating procedure. Results: During the period of study, 350 platelet pheresis donors were studied. All of the donors were male. Platelet yield showed high statistical significance with pre donation platelet count and its indices. (p=0.000). Statistical significant negative correlation was seen between pre donation Hb concentration and the platelet yield. (p =0.005). No statistical significance was seen height (p=0.933), weight (p=0.760) of donor on platelet yield. Conclusion: Platelet recovery in the patient is influenced by the transfused dose of platelets, which in turn is dependent on the quality of the platelet product in terms of yield. Various donor factors such as pre donation platelet count and haemoglobin concentration may affect platelet yield. J Dhaka Medical College, Vol. 28, No.2, October, 2019, Page 179-183

scholarly journals Plasma D-Dimer Level in Different Types of Acute Ischaemic Stroke Patients: Experience at a Tertiary Hospital in Dhaka City

2019 ◽  
Vol 5 (1) ◽  
pp. 13-17
Author(s):  
Paritosh Kumar Sarkar ◽  
Anwar Israil ◽  
Mohammad Sayeed Hassan ◽  
Abu Nayeem ◽  
Md Azharul Hoque ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Ischemic Stroke ◽  
Ischaemic Stroke ◽  
Clinical Diagnosis ◽  
Acute Ischaemic Stroke ◽  
Stroke Patients ◽  
College Hospital ◽  
Medical College ◽  
Different Types ◽  
D Dimer

Background: Plasma D-Dimer is a biomarker of thrombo-embolism. Objective: The purpose of the present study was to see the plasma D-dimer level in different types of acute ischaemic stroke patients. Methodology: This cross-sectional study was conducted in the Department of Neurology & Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2010 to June 2012 for a period of two (02) years. Patients with ischemic stroke with history within 7 days attending in the stroke clinic of Department of Neurology or admitted in the Department of Neurology and Internal Medicine through the outpatient and emergency Department of Dhaka Medical College Hospital (DMCH) were selected as study population for this study. Analysis of plasma D-Dimer was done in the Department of Hematology of DMCH.b Result: A total of 50 cases were recruited for this study. There were 24.0% lacunar infarcts, 40.0% atherothrombotic and 36.0% embolic infarcts in the study group. Highest level of plasma D-Dimer was observed in embolic (1700±964 ηg/ml) followed by atherothrombotic group (536±234 ηg/ml). The plasma D-Dimer was lowest (100±0 ηg/ml) in lacunar group. Concentration of Plasma D-Dimer showed significant correlation with clinical diagnosis in different subtypes of ischemic stroke (r=0.902; p=0.001) and also with risk factors, example, diabetes (r=0.319; p=0.012) and valvular heart disease (r=0.281; p=0.024), but no significant correlation with age, hypertension, hyperlipidaemia and smoking. Conclusion: In conclusion plasma D-Dimer is an important bio-marker in the clinical diagnosis and subtypes of ischemic stroke patients. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 13-17

scholarly journals Spectrum of dengue morbidity in pregnancy and its impact on maternal and perinatal outcome

2019 ◽  
Vol 8 (4) ◽  
pp. 1511
Author(s):  
Anuradha G. ◽  
Sandya M. R. ◽  
Shirley George
Keyword(s):  
Dengue Infection ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Severe Form ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Medical College ◽  
Still Births ◽  
Record Review ◽  
In Pregnancy

Background: Dengue is a vector borne viral infection with seasonal outbreaks every year. The spectrum varies from just a febrile morbidity to the severe form of dengue shock syndrome (DSS). The objective of the present study was to study the influence of dengue fever on pregnancy and to analyze the maternal and perinatal outcome.Methods: Thirty-six pregnant women beyond 28weeks of gestation who tested positive for dengue infection were retrospectively analyzed during a 5year study period (Jan 2014-Dec 2018). The study was conducted in the Department of OBGYN St John’s Medical College Hospital, Bangalore. Thirty-three of these patients delivered at St John’s and there were three postpartum referral cases. The necessary data was obtained by patient record review. The data was analyzed using SPSS and the results were expressed as Mean±SD and percentages.Results: Out of 36 women analyzed the mean age was found to be 23.93±4.5 years. Majority were primigravidae (58.3%). The most common clinical manifestation was fever seen in 47.2%. Twenty five percent of patients had platelet count of <20,000 on admission. Overall 66% of the patients required transfusion. Nearly fifty three percent of the patients had vaginal delivery. There were 4 maternal mortalities (11.1%) and 2 perinatal mortalities (5.5%) both were still births in the present study.Conclusions: Dengue infection in pregnancy was associated with increased maternal and perinatal morbidity as well as mortality. The severity of the infection has direct impact on the outcome. Hence early diagnosis and prompt management in a tertiary care centre, with multidisciplinary approach improves the outcome and minimizes the complications.

scholarly journals A cross sectional study on adequacy of blood transfusion and transfusion related infections in thalassemic patients attending a medical college hospital, West Bengal

2018 ◽  
Vol 5 (8) ◽  
pp. 3596
Author(s):  
Tarun Kumar Sarkar ◽  
Pulak Kumar Jana ◽  
Jasmine M. ◽  
Timiresh Kumar Das ◽  
Mrinmoy Adhikary ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
West Bengal ◽  
Ferritin Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Blood Samples ◽  
Medical College ◽  
Study Participants

Background: Thalassemia is more prevalent in India. The main treatment of Thalassemia is blood transfusion. But the transfusion of blood has many side effects like iron overload, transfusion related infections etc. The objectives of the study were to assess the adequacy of blood transfusion for thalassemic patients and to determine the magnitude of transfusion transmitted infections among those patients.Methods: A cross sectional study was conducted in Murshidabad Medical College and Hospital, West Bengal for 1 month with the sample size of 116. The blood samples from the patients were taken from the patients attending for blood transfusion in transfusion centre of Murshidabad Medical College and Hospital for two weeks dated from 24.04.2017 to 05.05.2017 to check for the hemoglobin, ferritin level and hepatitis B, C and HIV infection.Results: Among the 116 patients, even after transfusion, 94% of the study participants have their hemoglobin levels below 7 gm/dl. Only 2 individuals got their hemoglobin levels more than 9 gm/dl and only 1 patient got HIV infection post transfusion which accounts for 0.9% of study population.Conclusions: Frequent Hb estimation will help to maintain the adequacy of blood transfusion and proper screening of the blood before transfusion can help in reducing these transfusion transmitted infections.

scholarly journals Chorangioma - A Case Report

2014 ◽  
Vol 14 (2) ◽  
pp. 185-186
Author(s):  
Rehana Khanam ◽  
P.K. Ghosh ◽  
Fauzia Jahan ◽  
Saidur Rahman
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Live Birth ◽  
Microscopic Examination ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Caesarian Section ◽  
College Hospital ◽  
Medical College ◽  
Clinically Normal

We present a female patient with pregnancy associated with normal live birth and the unusual concomitance of chorangioma. It was an incidental finding during the routine microscopic examination of the placenta of the 30 year multipara whose pregnancy was clinically normal. She was admitted to the Bangladesh Medical College Hospital for labor at 34 weeks gestation. She was investigated thoroughly because of irregular pervaginal bleeding before delivary. Caesarian section was done at 37th weeks of pregnancy. The placenta was found enlarged, irregular and haemorrhagic. Histopathological examination from the sections of specimen was done and diagnosed as Chorangioma. The case is presented as below.DOI: http://dx.doi.org/10.3329/jom.v14i2.19671 J Medicine 2013, 14(2): 185-186

scholarly journals Clinical Presentation of Dengue in 150 Admitted Cases in Dhaka Medical College Hospital

1970 ◽  
Vol 7 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Md Abul Kalam Azad ◽  
Hanif Mohammad ◽  
Md Billal Alam ◽  
Anup Kumar Saha ◽  
Tofayel Ahmed
Keyword(s):  
Dengue Fever ◽  
Prospective Observational Study ◽  
Health Hazard ◽  
Dengue Shock Syndrome ◽  
Hemorrhagic Fever ◽  
Medical College Hospital ◽  
College Hospital ◽  
Medical College ◽  
Group 3 ◽  
Group 2

Dengue fever was not recognized as a major public health hazard in Bangladesh before 1999 outbreak, so there was little evidence and awareness in this regard. A prospective observational study was carried out to determine the risk group of patients suffering from dengue syndrome; clinical parameters of the subjects for hospitalization and the pattern of presentation of dengue fever in hospital care in different medicine units of Dhaka Medical College hospital from July 2000 to March 2001. Total 150 cases were selected randomly and diagnosed clinically as dengue, and were classified into 3 groups, i.e. 18 cases of classical dengue fever, 127 cases of dengue hemorrhagic fever (DHF-I and DHF-II) and 5 cases of dengue shock syndrome (DSS), and were discharged uneventfully. Among them 125(83.3%) were male and 25(16.7%) were female. Mean ages of the subjects were 26.75 ±3.69, 27.59 ± 1.18 and 10.67 ± 2.33 years in respective groups. Mean temperature was 103.45±0.28, 103.08±0.13, and 104.00±1.00 °F with mean duration was 5.50±0.51 days, 6.12±0.2 days, and 5.00±1.15 in respective groups. Majority had profound weakness, headache, myalgia, anorexia, nausea, and vomiting. Diarrhoea, abdominal pain, organomegaly, ascites, and pleural effusion were frequent complaints in group-3 patients, whereas infrequent complaints in other groups. Haemorrhagic manifestations were common in group 2 and 3 patients, melaena being the most common manifestations.   DOI = 10.3329/jom.v7i1.1355 J MEDICINE 2006; 7: 3-9

scholarly journals Incidence and predictors of severe obstetric morbidity in a teaching hospital

2017 ◽  
Vol 5 (2) ◽  
pp. 44-48
Author(s):  
Rupa Bajagain ◽  
Rachana Saha Saha
Keyword(s):  
Intensive Care Unit ◽  
Platelet Count ◽  
Elevated Liver Enzyme ◽  
Maternal Deaths ◽  
Medical College ◽  
Obstetric Haemorrhage ◽  
Before And After ◽  
Obstetric Morbidity ◽  
Low Platelet Count ◽  
Disease Specific

Background: Evaluation of severe obstetric morbidity is an important aspect of optimum maternal health. Towards this, the Water stone and Mantel criteria have been used to know the incidence, predictors and causes of severe obstetric morbidity.Objectives: The study aimed to estimate incidence, predictors and causes of obstetric morbidity at Kathmandu Medical College and Teaching Hospital.Methods: A hospital-based prospective study was carried out from 1st September 2014 to 31st August 2015. All cases of severe obstetric morbidity according to the Mantel and Water stone criteria were identified. The socio-demographic and healthcare characteristics of extremely severe cases were compared with controls which included women who were admitted before and after the indexed cases.Results: There were 2270 deliveries during the study period, out of which 74 cases of severe obstetric morbidities were identified i.e. an incidence of 32.5 per 1000 deliveries. During the study period, there were three maternal deaths attributed to conditions studied. Disease-specific morbidities per 1000 deliveries were 18.9 for haemorrhage, 9.2 for severe pre-eclampsia, 0.88 for eclampsia, 0.44 for haemolysis elevated liver enzyme and low platelet count and 3.08 for sepsis. A total of 26 patients were admitted in Intensive care unit which was 1.145 per 100 of total deliveries.Conclusion: Severe obstetric morbidity and its relation to mortality may be more sensitive measures of pregnancy outcome than mortality alone. In this study, most events are related to obstetric haemorrhage and severe pre-eclampsia.Journal of Kathmandu Medical College Vol. 5, No. 2, Issue 16, Apr.-Jun., 2016, page: 44-48

scholarly journals Study on ABO & Rhesus Blood Groups in Rajshahi Medical College Hospital

1970 ◽  
Vol 17 (1) ◽  
pp. 38-40
Author(s):  
MM Hossain ◽  
SFM Khyirul Ataturk ◽  
ARM Saifuddin Ekram ◽  
M Abul Kalam
Keyword(s):  
Blood Transfusion ◽  
Blood Groups ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Group A ◽  
Group B

About fifty two thousand admitted patients in different wards & cabins of Rajshahi Medical College Hospital are grouped in the Transfusion Medicine Department for the purpose of blood transfusion during the period of July/ 1997 to June/2000. It is found that out of 51966 patients, 16928 (32.38%) are group B, 16704(32.15%) are group O 13005 (25.02%) are group A, & 5329 (10.25%) are group AB, Among those patients, 50141 (96.51%) are Rh D positive, 1828(3.49%) are negative.   doi: 10.3329/taj.v17i1.3488 TAJ 2004; 17(1) : 38-40

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