scholarly journals Study on Palmar Dermatoglyphics and their Association with β Thalassemia Major Patients among Bangladeshi Population

Mediscope ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 94-102
Author(s):  
Afroj Zahan ◽  
Humaira Naushaba ◽  
Uttam Kumar Paul ◽  
AHM Mazharul Islam ◽  
Sharna Moin ◽  
...  
Keyword(s):  
Thalassemia Major ◽  
Diagnostic Value ◽  
Control Group ◽  
Case Group ◽  
Healthy Individuals ◽  
Ridge Count ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
Bangladeshi Population

Objectives: To observe the palmar dermatoglyphic patterns of β thalassemia major patients. Methods: This cross-sectional type of analytical study was performed in the Department of Anatomy, Sir Sallimullah Medical College, Dhaka between the periods of January 2016 to December 2016. 55 β thalassemia major patients aged between (5-35) years were considered as case group and 55 healthy individuals of the same age & sex were considered as control group in this study. The palmar dermatoglyphic patterns and Total Finger Ridge count (TFRC) on the distal phalanges of the β thalassemia major patients were observed and compared with healthy individuals. Results: The palmar dermatoglyphic patterns were significantly different between the two groups (p > 0.05). The mean (±SD) of Total Finger Ridge count (TFRC) were higher in β thalassemia major patients in comparison to the healthy individuals. Conclusion: This study concludes that, palmar dermatoglyphic has a diagnostic value for β thalassemia major patients. Mediscope 2021;8(2): 94-102

A STUDY OF HYPERURICACIDEMIA AND THE PRESENCE AND SEVERITY OF ACUTE CORONARY SYNDROME IN INDEX MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTER, INDORE ( M.P.)

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
B. Khanam ◽  
M. Imran Khan ◽  
Ajay Kumar Singh ◽  
Sumit Solanki ◽  
S.M. Holkar
Keyword(s):  
Acute Coronary Syndrome ◽  
Control Group ◽  
Case Group ◽  
College Hospital ◽  
Medical College ◽  
Coronary Syndrome ◽  
Luminal Stenosis ◽  
Angiographic Evidence ◽  
The Mean ◽  
High Uric Acid

Background: Few studies have assessed the relation of hyperuricacidemia with the acute coronary syndrome (ACS). This study investigated the association between high uric acid levels with the presence and severity of ACS.  Methods: Three hundred and seventy patients having angiographic evidence of atherosclerosis (CAD + case group) compared to 170 patients with no luminal stenosis (n=110) or with <50% luminal stenosis (n=60) at coronary angiography (CAD – control group). Results: The mean age of the patients was 60 ± 10 years (317 men, 58.7%). Hyperuricacidemia was more likely associated with a trend toward higher vessel scores, indicating a more severe CAD (adjusted OR=1.51, 95% CI=1.09-2.09; P=0.005) in the whole population. A comparison of sex-specific values showed a significant association existed only in men. Conclusions: Asymptomatic hyperuricacidemia may be associated with the presence and severity of ACS. Keywords: Hyperuricacidemia, Severity & Acute Coronary Syndrome.

scholarly journals Hematological changes in pregnancy induced hypertension in their third trimester at Jhalawar Medical College, Jhalawar, India

2019 ◽  
Vol 8 (9) ◽  
pp. 3497
Author(s):  
Neelam Jhajharia ◽  
Madhureema Verma
Keyword(s):  
Control Group ◽  
Case Group ◽  
Haematocrit Level ◽  
Haematological Parameter ◽  
Pregnancy Induced Hypertension ◽  
Medical College ◽  
Induced Hypertension ◽  
Life Threatening ◽  
The Mean ◽  
And Control

Background: Pregnancy induced hypertension (PIH) is one of the most common and potential life-threatening complications of pregnancy. This study is aimed to investigate and correlate the hemoglobin, haematocrit, white blood cell count, lymphocytes and platelets in PIH patients in their third trimester.Method: Total 126 subjects were studied out of them 63 patients (case) and 63 healthy pregnant women (control) visiting the Obstetrics and Gynaecology department Jhalawar Medical College, Jhalawar were registered in the study and followed during their pregnancy. Two millilitre of blood sample was drawn aseptically using the 5ml syringe from the median ante cubital vein of all the cases and control participants into EDTA-anticoagulated tubes. Haematological parameter calculated by using Sysmex XN-9100™ Automated Haematology System.Results: The mean hemoglobin level of the case group (8.8206±2.53779) was significantly lower than that of the control group (9.7289±2.47033) (p<0.05). The mean platelet count of the case group (131.4937±62.05999) was significantly lower than that of the control group (324.9683±230.78764) (p<0.05). The mean lymphocytes level of case group (1.2510±0.56369) was significantly lower than that of the control group (1.9295±1.4150) (p<0.05). The mean WBC level of case group (36.3467±119.90635) was significantly high than control group (11.5260±4.83059) (p<0.05). The mean haematocrit level of case group (32.6851±7.29789) was significantly high than control group (30.0424±23.38116) (p<0.05).Conclusion: The mean hemoglobin, mean platelets and mean lymphocytes are lower in PIH patients. The mean WBC and haematocrit are higher in PIH patient. 

scholarly journals Association of Hypertension and Smoking with Ischaemic Stroke

2013 ◽  
Vol 3 (1) ◽  
pp. 16-18
Author(s):  
K Kirtania ◽  
N Sultana ◽  
S Ahmed ◽  
A Khatun
Keyword(s):  
Cigarette Smoking ◽  
Ischaemic Stroke ◽  
Matched Control ◽  
Strong Relationship ◽  
Control Group ◽  
Case Group ◽  
Medical College ◽  
Study Population ◽  
The Mean ◽  
Control Study

Hypertension is one of the most important modifiable risk factors for ischemic stroke. Cigarette smoking is a risk factor for atherosclerotic disease. There is a strong relationship between hypertension and cigarette smoking with ischaemic stroke. A case control study was undertaken to see the association of hypertension and cigarette smoking with ischaemic stroke. The study was done from January to December 2009 in the Department of Biochemistry, Dhaka Medical College, Dhaka. A total of 60 subjects were selected as study population. Among them 30 were diagnosed case of ischaemic stroke and 30 were age-and sex-matched control subjects. It was found that 60% patients of case group and 20% respondents of control group were hypertensive and diffrence was significant. Study showed that 56.66% of cases and 53.33% of controls were smoker and the findings were insignificant. The mean duration of smoking was 27.41 ± 2.98 years in cases and 15.63 ± 2.85 years in controls which was significant. The study suggests that hypertension is significantly associated with ischaemic stroke and longer duration of smoking also associated with ischaemic stroke. DOI: http://dx.doi.org/10.3329/bjmb.v3i1.13802 Bangladesh J Med Biochem 2010; 3(1): 16-18

scholarly journals Histomorphometric Study of the Glomeruli of the Kidney in Bangladeshi Population

2015 ◽  
Vol 9 (1) ◽  
pp. 11-16
Author(s):  
Fatema Johora ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Sunjida Shahriah ◽  
Rukshana Ahmed ◽  
Shamim Ara
Keyword(s):  
Left Kidney ◽  
Age Groups ◽  
Population Based ◽  
Cross Sectional ◽  
Medical College ◽  
Histomorphometric Study ◽  
The Mean ◽  
Group 10 ◽  
Bangladeshi Population ◽  
The Right

Background: Controversies still prevail on glomerular changes of kidney whether due to normal aging or its association with diseases Objective: The aim of the present study was to see the variation in number and size of the glomeruli of kidney with increasing age in a Bangladeshi population based on autopsy. Methods: This cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2008 to June 2009, based on collection of 140 post mortem human kidneys collected from 70 unclaimed dead bodies from the morgue. All the samples were divided into three age-groups: 10-19 years, 20-39 years and 40-59 years. Histological slides were prepared by using routine Harris’ Haematoxylin and Eosin (H & E) stain. The number of glomeruli was measured by point counting technique, while the size (diameter) was measured by using ocular and stage micrometer. Results: The mean ± SE number of glomeruli per sq. mm found in the right and left kidney were 8.45±0.52 and 8.67±0.80 in group 10-19 years, 9.90±0.42 and 9.92±0.47 in 20-39 years, and 8.52±0.18 and 8.55±0.16 in 40-59 years respectively. Besides, the size (mean ± SE diameter) of glomeruli was found in the right and left kidney were 43.96±3.01ìm and 143.92±2.90ìm in group 10-19 years, 153.69±5.18ìm and 153.61±5.24ìm in 20-39 years, and 140.48±0.95ìm and 140.78±0.88ìm in 40-59 years respectively. Conclusion: No difference was found in number and size of glomeruli between right and left kidney in any group. Similarly, no difference was also evident among different age groups. DOI: http://dx.doi.org/10.3329/jbsp.v9i1.22788 Bangladesh Soc Physiol. 2014, June; 9(1): 11-16

scholarly journals Serum Dihydropyrimidinase-Like 3 Concentration in Patients with Gastric Cancer and Its Diagnostic Value

2021 ◽  
Author(s):  
Huiqiu Zhong ◽  
Xiaojiang Luo
Keyword(s):  
Gastric Cancer ◽  
Diagnostic Value ◽  
Control Group ◽  
Case Group ◽  
Serum Concentrations ◽  
Medical College ◽  
Healthy Control ◽  
Serum Cea ◽  
Gastric Cancer Patients ◽  
Group Serum

Background: We aimed to investigate the serum concentration of dihydropyrimidinase-like 3 (DPYSL3) in patients with gastric cancer and its clinical significance. Methods: Seventy four patients with gastric cancer from Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, China from October 2018 to April 2019 were selected as the case group. Sixty patients with normal gastric mucosa or mild non-atrophic gastritis were selected as the control group. Serum DPYSL3, CA72-4 and CEA concentrations were measured in both groups. Results: The serum DPYSL3 concentration in the case group was significantly higher than that in the healthy control group (22.04±9.22 vs. 8.36±4.19 μg/L, P<0.001). The serum DPYSL3 concentration in patients with advanced gastric cancer was significantly higher than that in early gastric cancer (27.09±9.12 vs. 13.04±8.22 μg/L, P<0.01); serum DPYSL3 concentration was significantly correlated with tumor size, TNM stage and differentiation (P<0.05). When the cutoff value was 20.98 μg/L, the serum DPYSL3 concentration could differentiate the gastric cancer with ROCAUC 0.882 (95% CI: 0.828-0.937) with sensitivity and specificity of 75% and 94%, respectively. Serum CA72-4 concentration could differentiate the gastric cancer from health controls with ROCAUC 0.812 (95% CI: 0.734-0.834), serum CEA concentration could differentiate gastric cancer with ROCAUC 0.612 (95% CI: 0.534 ~ 0.634). The serum concentrations of DPYSL3, CA72-4 and CEA in gastric cancer patients were increased compared to health controls. Conclusion: Three serological markers have complementary diagnostic value for gastric cancer. Serum DPYSL3 is a new potential molecular marker for gastric cancer.

scholarly journals Evaluation of Oxidative Stress in Patients with Fracture Admitted to Khatam Al-Anbia Hospital in Zahedan

2020 ◽  
Vol 18 (3) ◽  
Author(s):  
Mansour Karajibani ◽  
Farzaneh Montazerifar ◽  
Faezeh Kazemi ◽  
Ali Reza Dashipour
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activities ◽  
Control Group ◽  
Case Group ◽  
Cross Sectional ◽  
Stress Markers ◽  
Significant Difference ◽  
Before And After ◽  
Markers Of Oxidative Stress ◽  
The Mean

Background: Caused by an imbalance in the body’s oxidant and antioxidant status, oxidative stress can give rise to tissue damage and exacerbation of many diseases. Objectives: This study investigated the oxidative stress markers in patients with fractures and healthy subjects. Methods: In a cross-sectional case-control study, 40 patients with fractures admitted to an orthopedic ward and 40 healthy, non-fractured patients were selected using convenience sampling. Serum was analyzed for oxidant and antioxidant activities based on standard methods. P < 0.05 was considered statistically significant. Results: There was a significant difference in mean TAC between the case (748.2 ± 302.83 μmol/L) and control (984.90 ± 207.02 μmol/L) groups (P = 0.003). The mean MDA was 16.61 ± 4.16 µmol/L in the case group and 18.45 ± 5.43 µmol/L in the control group (P = 0.09). The mean SOD was 63.41 ± 16.67 U/g Hb in the case group and 58.54 ± 21.83 U/g Hb in the control group (P = 0.2). There was no significant difference between the two groups in terms of BMI and other variables. Conclusions: A significant difference existed in TAC between the two groups, which indicated increased oxidative stress in patients. However, oxidative stress could occur before and after undergoing fractures. The results suggested a slight, but not significant, difference between the two groups in the SOD and MDA scores. More conclusive results are required to determine the enzymatic and non-enzymatic markers of oxidative stress in larger sample sizes and during different stages of treatment.

scholarly journals Study on weight of the postmortem parathyroid glands in a Bangladeshi population

2013 ◽  
Vol 22 (1) ◽  
pp. 34-38
Author(s):  
Sabiha Mahbub ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Abdul Alim ◽  
Rukshana Ahmed ◽  
Shamim Ara
Keyword(s):  
Age Groups ◽  
Parathyroid Glands ◽  
Cross Sectional ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Bangladeshi Population ◽  
Group B ◽  
The Right

Context: A cross-sectional descriptive type of study was designed to find out the difference in weight of the parathyroid glands of Bangladeshi people in relation to age and sex and to compare with the previous studies. Methods: This study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008. The study was performed on 207 post mortem human parathyroid glands collected from 60 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age-groups including group A (10-30 years), group B (31-60 years) & group C (61-90 years) and the weight of the parathyroids were measured and recorded. Results: The mean weight of the right superior parathyroid glands were 13.43±13.77 mg in group A, 13.86±19.15 mg in group B and 9.25±5.12 mg in group C in males and 16.00±6.69 mg in group A and 8.57±5.97 mg in group B in females respectively. The mean weight of the right inferior parathyroids were 17.78±13.94 mg, 16.75±15.67 mg and 23.00±11.53 mg in group A, B and C respectively in males and 26.00±4.18 mg in group A and 15.20±4.32 mg in group B in females. The mean weight of the left superior parathyroid glands were 13.63±6.08 mg in group A, 10.58±7.57 mg in group B and 11.00±3.74 mg in group C in males and 16.20±7.89 mg in group A and 8.29±5.47 mg in group B in females respectively. The mean weight of the left inferior parathyroid gland was 26.11±24.29 mg, 15.81±10.28 mg and 25.25±25.28 mg in group A, B and C respectively in males and 32.25±13.82 mg in group A and 13.29±5.41 mg in group B in females. No difference was found in the weight of superior parathyroid glands at right side between sexes and age groups excepting in superior and inferior parathyroid glands at left side between group A & B (p<0.05). DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15603 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 34-38

scholarly journals Assessment of religious coping in patients with COPD

2020 ◽  
Vol 46 (1) ◽  
Author(s):  
Francisco Alessandro Braga do Nascimento ◽  
Guilherme Pinheiro Ferreira da Silva ◽  
Geisyani Francisca Gomes Prudente ◽  
Rafael Mesquita ◽  
Eanes Delgado Barros Pereira
Keyword(s):  
Quality Of Life ◽  
Depressive Symptoms ◽  
Religious Coping ◽  
Control Group ◽  
Inverse Association ◽  
Healthy Individuals ◽  
Cross Sectional ◽  
The Mean ◽  
Minute Walk

ABSTRACT Objective: To compare religious coping (RC) in patients with COPD and healthy individuals, as well as to determine whether RC is associated with demographic characteristics, quality of life, depression, and disease severity in the patients with COPD. Methods: This was a cross-sectional study conducted between 2014 and 2016, involving outpatients with moderate to severe COPD seen at one of two hospitals in Fortaleza, Brazil, as well as gender- and age-matched healthy controls. The Brief RCOPE scale assessed RC in all of the participants. We also evaluated the COPD group patients regarding symptoms, quality of life, and depression, as well as submitting them to spirometry and a six-minute walk test. Results: A total of 100 patients were evaluated. The mean age was 67.3 ± 6.8 years, and 54% were men. In the COPD group, the mean positive RC score was significantly higher than was the mean negative RC score (27.17 ± 1.60 vs. 8.21 ± 2.12; p = 0.001). The mean positive RC score was significantly higher in women than in men (27.5 ± 1.1 vs. 26.8 ± 2.8; p = 0.02). Negative RC scores were significantly higher in the COPD group than in the control group (p = 0.01). Negative RC showed an inverse association with six-minute walk distance (6MWD; r = −0.3; p < 0.05) and a direct association with depressive symptoms (r = 0.2; p < 0.03). Positive RC correlated with none of the variables studied. Multiple regression analysis showed that negative RC was associated with 6MWD (coefficient = −0.009; 95% CI: −0.01 to −0.003). 6MWD explained the variance in negative RC in a linear fashion. Conclusions: Patients with COPD employ negative RC more often than do healthy individuals. Exercise capacity and depressive symptoms are associated with negative RC.

scholarly journals A postmortem study on morphometry of the human stomach in a Bangladeshi population

2013 ◽  
Vol 22 (1) ◽  
pp. 16-18
Author(s):  
Gul Newaz Begum ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Sunjida Shahriah ◽  
Khandaker Abu Rayhan ◽  
Hosna Ara Perven
Keyword(s):  
Age Groups ◽  
Human Stomach ◽  
Cross Sectional ◽  
Medical College ◽  
C 23 ◽  
Group A ◽  
Measuring Tape ◽  
The Mean ◽  
Bangladeshi Population ◽  
Group B

Context: A Cross-sectional, descriptive type of study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2005 to June 2006, to see the variation in the size of the stomach with age in Bangladeshi people. Methods: The study was performed on 60 post mortem human stomach collected from unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including group A (2-16 years), group B (17-22 years) and group C (23-65 years). The length and breadth of each stomach were measured by using a measuring tape. Results: The mean length of the stomach were found 12.18±1.77 cm in group A, 17.74±1.95 cm in group B, and 25.31±1.63 cm in group C. The mean breadth of the stomach were found 6.81±0.40 cm, 8.26±0.57 cm and 9.54±0.45 cm in group A, B and C respectively. The differences between age groups were statistically significant (P<0.001). Conclusion: The length and breadth of the human stomach increase with age. DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15598 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 16-18

scholarly journals SOCIO-DEMOGRAPHIC PROFILE IN PREECLAMPSIA

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Kumari Amrita ◽  
Verma Asha ◽  
Bajiya Monika ◽  
Gurjar Anil ◽  
Muhal Poonam
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Medical College ◽  
Maternal Morbidity And Mortality ◽  
The Mean ◽  
Cardiac System ◽  
New Onset

Background: Pre-eclampsia is a complex multisystem condition. It affects 3-5% of all prenancies.It is defined as new onset hypertension after twenty weeks of pregnancy plus involvement of at least one organ system-renal, hepatic, neurological, hematological, pulmonary or cardiac system or as utero-placental dysfunction Methods: This was a hospital based comparative analytical cross sectional study carried out over 2 years period from may 2019 in the Department of Obstetrics and Gynecology, SMS Medical College and attached hospitals, Jaipur. Results:  The mean age of cases (27.36 ± 3.66 years) was higher than the controls (23.43 ± 3.23 years). There was not much difference in the distribution of subjects according to residence. In the study group 26 (57.78%) women belonged to urban areas and 19 (42.22%) belonged to rural areas whereas in the control group, 26 (62.22%) women belonged to rural areas and 17 (37.78%) belonged to urban areas. There were more primigravida in pre eclamptic group compared to the control group. Conclusion: Identification of risk factor in the antenatal period helps in early detection of women who are at high risk of developing pre-eclampsia in order to reduce maternal morbidity and mortality. Keywords: Preclampsia, Age, Gravida

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