ENDOCRINE PROFILE OF THE MALE POPULATION IN RUSSIA DEPENDING ON THE GEOGRAPHIC LATITUDE OF OCCUPATION

Standardized mortality rates of the male population aged 15-59 in Monchegorsk, where the Kola mining and metallurgical company is located, were higher relative to the Murmansk region and Russia: from diseases of the circulatory system by 34.8% and 52.1%, respectively, from malignant neoplasms by 26.3% and 19.4%, from diseases of the digestive system by 59.0% and 36.3%.

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Estimation of Stature from Somatometric Parameters in Male Population

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2020.12.03.352 ◽

2020 ◽

Vol 12 (03) ◽

Keyword(s):

Male Population

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STUDY CLINICAL FEATURE AND RESULT OF TREATMENT PHACOMORPHIC GLAUCOMA

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2015.1.9 ◽

2015 ◽

pp. 71-75

Author(s):

Van Nam Phan ◽

Ba Ken Tran

Keyword(s):

Visual Acuity ◽

Intraocular Pressure ◽

Statistical Significance ◽

Corneal Edema ◽

Clinical Feature ◽

Anterior Chamber Angle ◽

Male Population ◽

Significant Difference ◽

Operative Complications ◽

Before And After

Purpose: Study clinical feature of phacomorphic glaucoma. To evaluate the result of treatment phacomorphic glaucoma. Method: The retrospective, interventional study on 36 cases with phacomorphic glaucoma who underwent treated at Hue Central Hospital from 6/2010 to 6/2011. Standard of research: visual, IOP, before and after surgery, accompanying lesions and post-operative complications. The surgery is considered successful when postoperative IOP less than 21 mmHg. Results: Age 50-59 presented 30.5 percent, ≥ 60 presented 91.7 percent. There was a slight female preponderance (66.7%) compared to the male population (33.3%) which implies a statistically marginally significant difference. However there was no statistical significance difference when compared by the two subgroups. Patient in country presented 61,1% and city presented 38,9%. The duration between the onset of pain and surgery from 0 to < 5 days (77.8%), from 6 to 10 (16.7%) and >10 days presented 5.5%. The preoperative intraocular pressure 35 to 45mmHg (47.2%), 46-55 (30.6%), 56-65 (13.9%) and more than 65 presented 8.3%. The visual acuity preoperation less than 1metre count finger (94.5%), less than 3 metre count finger presented 5.5%. Close anterior chamber angle presented 80.6% and shallow was presented 19.4%. Corneal edema presented 100%, iritis presented 94.4%, dilated pupil larger 5mm presented 83.3%, Synchynea iris and cataract presented 72.2%. ECCE, implantation IOL combined trabeculectomy presented 11.1%, Phaco, implantation IOL combined trabeculectomy presented 69,5%, ECCE implantation IOL presented 5.6%, Phaco, implantation IOL presented 13.8%. Postoperative visual acuity from 1/10 to 5/10 presented 72.2%, no case have VA larger than 5/10. Postoperative 3 months VA 1/10 to 5/10 presented 72.2%, larger VA 5/10 presented 8.3%. Postoperative 3 months intraocular pressure ≤ 21mmHg presented 91.7%, 22 to 24mmHg presented 8.3%, no case have IOP ≥25mmHg. Postoperative edema presented 58.3%, iritis presented 58.3%. Key words: phacomorphic Glaucoma

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The correlation between lipid metabolism disorders and the prostate cancer

Current Medicinal Chemistry ◽

10.2174/0929867327666200806103744 ◽

2020 ◽

Vol 27 ◽

Author(s):

Justyna Dłubek ◽

Jacek Rysz ◽

Zbigniew Jabłonowski ◽

Anna Gluba-Brzózka ◽

Beata Franczyk

Keyword(s):

Prostate Cancer ◽

Fatty Acids ◽

Lipid Metabolism ◽

Cancer Progression ◽

De Novo ◽

Prostate Gland ◽

Hdl Cholesterol ◽

Atp Citrate Lyase ◽

Male Population ◽

Lipid Metabolism Disorders

: Prostate cancer is second most common cancer affecting male population all over the world. The existence of a correlation between lipid metabolism disorders and cancer of the prostate gland has been widely known for a long time. According to hypotheses, cholesterol may contribute to prostate cancer progression as a result of its participation as a signalling molecule in prostate growth and differentiation via numerous biologic mechanisms including Akt signalling and de novo steroidogenesis. The results of some studies suggest that increased cholesterol levels may be associated with higher risk of more aggressive course of disease. The aforementioned alterations in the synthesis of fatty acids are a unique feature of cancer and, therefore, it constitutes an attractive target for therapeutic intervention in the treatment of prostate cancer. Pharmacological or gene therapy aimed to reduce the activity of enzymes involved in de novo synthesis of fatty acids, FASN, ACLY (ATP citrate lyase) or SCD-1 (stearoyl-CoA desaturase) in particular, may result in cells growth arrest. Nevertheless, not all cancers are unequivocally associated with hypocholesterolaemia. It cannot be ruled out that the relationship between prostate cancer and lipid disorders is not a direct quantitative correlation between carcinogenesis and the amount of the circulating cholesterol. Perhaps the correspondence is more sophisticated and connected to the distribution of cholesterol fractions, or even sub-fractions of e.g. HDL cholesterol.

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The Inflammation Network in the Pathogenesis of Erectile Dysfunction: Attractive Potential Therapeutic Targets

Current Pharmaceutical Design ◽

10.2174/1381612826666200424161018 ◽

2020 ◽

Vol 26 (32) ◽

pp. 3955-3972

Author(s):

Ecem Kaya-Sezginer ◽

Serap Gur

Keyword(s):

Erectile Dysfunction ◽

Endothelial Dysfunction ◽

Metabolic Diseases ◽

Inflammatory Marker ◽

Attractive Potential ◽

Common Denominator ◽

Low Grade ◽

Antiinflammatory Drugs ◽

Male Population ◽

Low Grade Inflammation

Background: Erectile dysfunction (ED) is an evolving health problem in the aging male population. Chronic low-grade inflammation is a critical component of ED pathogenesis and a probable intermediate stage of endothelial dysfunction, especially in metabolic diseases, with the inclusion of obesity, metabolic syndrome, and diabetes. Objective: This review will present an overview of preclinical and clinical data regarding common inflammatory mechanisms involved in the pathogenesis of ED associated with metabolic diseases and the effect of antiinflammatory drugs on ED. Methods: A literature search of existing pre-clinical and clinical studies was performed on databases [Pubmed (MEDLINE), Scopus, and Embase] from January 2000 to October 2019. Results: Low-grade inflammation is a possible pathological role in endothelial dysfunction as a consequence of ED and other related metabolic diseases. Increased inflammation and endothelial/prothrombotic markers can be associated with the presence and degree of ED. Pharmacological therapy and modification of lifestyle and risk factors may have a significant role in the recovery of erectile response through reduction of inflammatory marker levels. Conclusion: Inflammation is the least common denominator in the pathology of ED and metabolic disorders. The inflammatory process of ED includes a shift in the complex interactions of cytokines, chemokines, and adhesion molecules. These data have established that anti-inflammatory agents could be used as a therapeutic opportunity in the prevention and treatment of ED. Further research on inflammation-related mechanisms underlying ED and the effect of therapeutic strategies aimed at reducing inflammation is required for a better understanding of the pathogenesis and successful management of ED.

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Serum Endocrine Profile in Relation to Estrus Synchronization in Surti Does

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.v13i03.10609 ◽

2018 ◽

Vol 13 (03) ◽

Author(s):

M. M. Chaudhary ◽

C. T. Khasatiya ◽

S. B. Patel ◽

S. S. Chaudhary ◽

V. B. Atara ◽

...

Keyword(s):

Jugular Vein ◽

Estrus Synchronization ◽

Progesterone Concentration ◽

Serum Progesterone ◽

Blood Samples ◽

Group Iii ◽

Group I ◽

Endocrine Profile ◽

Group Ii ◽

And Control

The serum progesterone and estradiol profiles during synchronization of estrus by buck effect and PGF2α treatments were monitored in Surti does. Total eighteen non-pregnant does selected were evenly divided into 3 groups, 6 does in each group. The does of Group I were teased with a sexuallyactive- apronized buck; and those of Group II were treated with PGF2α, i.e., Inj. Lutalyse® @ 7.5 mg/doe IM twice 11 days apart, while the Group III served as untreated control. Blood samples were collected from all the animals on day 0 (before 1st PGF2α injection), 3rd day (during treatment), 11th day (before 2nd PGF2α injection), 14th day (after treatment) and 40th day (post-service) by jugular vein puncture. The serum separated was stored at -20°C till further analysis. In all the three groups, 83.33% does, conceived at first service in the sampling cycle. The overall mean serum progesterone concentration of Group I does (5.82±0.72 ng/ml) was significantly higher (p less than 0.01) as compared to Group II (2.93±0.38 ng/ml) and III (2.88±0.30 ng/ml). Similarly, the overall mean serum progesterone concentration of Surti does on day 0 (2.65±0.46 ng/ml), 3rd (2.56±0.80 ng/ml), 11th (4.45±0.84 ng/ml) and 14th (3.40±0.63 ng/ml) did not differ significantly, but the overall mean level at day 40 (6.31±0.45 ng/ml) was significantly (p less than 0.01) higher, because most of animals became pregnant at that time. The overall mean serum oestradiol-17β levels of Group I (24.40±2.98 pg/ ml) was significantly higher (p less than 0.01) than in Group II (15.77±1.77 pg/ml) and III (12.21±1.45 pg/ ml). On the other hand, the overall mean serum oestradiol-17β levels of Surti does on day 0 (12.89±1.21 pg/ml), 3rd (15.84±1.74 pg/ml), 11th (14.81±1.96 pg/ml), 14th (22.15±2.97 pg/ml) and 40th (21.64±5.16 pg/ml) did not differ significantly (p>0.05) and the slightly higher overall mean level found at 40th day might be the influence of the non-pregnant does at first service in the cumulative animals. The hormonal profile reflected the initiation of cyclicity and establishment of pregnancy in treated and control animals.

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Blood Lipid Levels in a Rural Male Population

European Journal of Cardiovascular Prevention & Rehabilitation ◽

10.1177/174182670100800308 ◽

2001 ◽

Vol 8 (3) ◽

pp. 165-174 ◽

Cited By ~ 3

Author(s):

A. Thelin ◽

E.-L. Stiernstrom ◽

S. Holmberg

Keyword(s):

Blood Lipid ◽

Lipid Levels ◽

Male Population ◽

Blood Lipid Levels

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To Establish A Normal Range of Inter-Incisal Opening - A Study of 756 Subjects of Age Group 20-50 Years in Yamunanagar City, Haryana.

Dental Journal of Advance Studies ◽

10.1055/s-0038-1670583 ◽

2013 ◽

Vol 01 (01) ◽

pp. 001-003

Author(s):

Aruna Singh ◽

Nymphea Pandit ◽

Monica Sharma

Keyword(s):

Pearson Correlation ◽

Mouth Opening ◽

Clinical History ◽

P Value ◽

Age Group ◽

Male Population ◽

Female Population ◽

Odontogenic Infections ◽

Anterior Teeth ◽

Average Maximum

Abstract Aim- 1. The aim of this study was to investigate the average maximum range of inter-incisal mouth opening in a representative sample of the adult subjects of Haryana. 2. To see any correlation between maximal inter-incisal opening with age. Methods- Maximum mouth opening was studied in 756 adult subjects with age range of 20-50 years in Yamunanagar, Haryana. Age limit was further divided into three groups (20-30, 31-40, 41-50). Those with clinical history of TMJ involvement, OSMF, any trauma, odontogenic and non-odontogenic infections, dental prosthesis on the anterior teeth, congenital anomalies in the maxillofacial region were excluded from this study. The measurements were recorded twice and mean of the two values were taken. Statistical Analysis- Independent sample t-test was calculated to compare age and mouth opening in both male and females respectively. Bivariate pearson correlation was used to see any relationship between age and mouth opening. P-value ≤ 0.05 and CI (confidence interval) at 95% were considered statistically significant. The Results- The average mouth opening of males (45.36±6.70 mm) subjects was higher as compared to female (41.27 ± 6.75 mm) with significant, p-value 0.000. The mean mouth opening ± SD for both sexes combined was 43.39 ± 7.02 mm. The corresponding values for mean inter-incisal opening in male population aged 20-30, 31-40, 41-50 were 45.52 ± 7.15, 46.16 ± 5.47, 42.96 ± 6.82 mm and in female population aged 20-30, 31-40, 41-50 were 41.40 ± 7.08, 41.60 ± 6.29 and 40.03 ± 6.38 mm respectively. Conclusion- Maximal mouth opening differ significantly with gender. There is a decrease in MMO with older age group.

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