scholarly journals Research Progress on Cell Membrane-Coated Biomimetic Delivery Systems

Author(s):  
Mengyu Guo ◽  
Chenjie Xia ◽  
Yu Wu ◽  
Nong Zhou ◽  
Zhipeng Chen ◽  
...  

Cell membrane-coated biomimetic nanoplatforms have many inherent properties, such as bio-interfacing abilities, self-identification, and signal transduction, which enable the biomimetic delivery system to escape immune clearance and opsonization. This can also maximize the drug delivery efficiency of synthetic nanoparticles (NPs) and functional cell membranes. As a new type of delivery system, cell membrane-coated biomimetic delivery systems have broadened the prospects for biomedical applications. In this review, we summarize research progress on cell membrane biomimetic technology from three aspects, including sources of membrane, modifications, and applications, then analyze their limitations and propose future research directions.

2020 ◽  
Vol 143 ◽  
pp. 02027
Author(s):  
Zhao Bin ◽  
Cheng Yongqiang ◽  
Guo Cuilian ◽  
Liu Maoke ◽  
Yao Puyu ◽  
...  

Microplastics are attracting more and more attention as a new type of pollutant in the ecological environment. Microplastics are difficult to degrade because of their unique physical and chemical properties. Some microplastics adsorbed toxic chemicals (e.g. heavy metals or organic pollutants) will cause a series of toxicological effects in organisms. This paper summarized the research progress in microplastics from the aspects of the types, distribution, detection and the toxicological effects. In addition, future research directions were also proposed and discussed.


2021 ◽  
Vol 1036 ◽  
pp. 20-31
Author(s):  
Jun Jie Ye ◽  
Zhi Rong He ◽  
Kun Gang Zhang ◽  
Yu Qing Du

Ti-Ni based shape memory alloys (SMAs) are of excellent shape memory effect, superelasticity and damping property. These properties of the alloys can be fully displayed only after proper heat treatment. In this paper, the research progresses of the effect of the heat treatment on the microstructure, phase composition, phase transformation behaviors and shape memory properties in Ti-Ni based SMAs are reviewed, the correlation influence mechanism is summarized, and the future research directions in this field are pointed out. It is expected to provide reference for the development of Ti-Ni based SMAs and their heat treatment technologies.


2018 ◽  
Vol 6 (40) ◽  
pp. 10672-10686 ◽  
Author(s):  
Qing Zhang ◽  
Huanli Dong ◽  
Wenping Hu

This article places special focus on the recent research progress of the EP method in synthesizing CPs. In particular, their potential applications as 2D CPs are summarized, with a basic introduction of the EP method, its use in synthesizing CPs as well as the promising applications of the obtained CPs in different fields. Discussions of current challenges in this field and future research directions are also given.


2019 ◽  
Vol 90 (5-6) ◽  
pp. 710-727 ◽  
Author(s):  
Yiwei Ouyang ◽  
Xianyan Wu

In order to review the most effective ways to improve the mechanical properties of composite T-beams and further increase their application potential, research progress on the mechanical properties of textile structural composite T-beams was summarized based on two-dimensional (2-D) ply structure composite T-beams, delamination resistance enhanced 2-D ply structure T-beams, and three-dimensional (3-D) textile structural composite T-beams; future research directions for composite T-beams were also considered. From existing literature, the research status and application bottlenecks of 2-D ply structure composite T-beams and T-beams with enhanced delamination resistance performance were described, as were the specific classification, research progress, and mechanical properties of 3-D textile structural composite T-beams. In addition, the superior mechanical properties of 3-D braided textile structural composite T-beams, specifically their application potential based on excellent delamination resistance capacity, were highlighted. Future research directions for composite T-beams, that is, the applications of high-performance raw materials, locally enhanced design, structural blending enhancement, functionality, and intelligence are presented in this review.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Huixin Wu ◽  
Feng Wang

Zero knowledge proof system which has received extensive attention since it was proposed is an important branch of cryptography and computational complexity theory. Thereinto, noninteractive zero knowledge proof system contains only one message sent by the prover to the verifier. It is widely used in the construction of various types of cryptographic protocols and cryptographic algorithms because of its good privacy, authentication, and lower interactive complexity. This paper reviews and analyzes the basic principles of noninteractive zero knowledge proof system, and summarizes the research progress achieved by noninteractive zero knowledge proof system on the following aspects: the definition and related models of noninteractive zero knowledge proof system, noninteractive zero knowledge proof system of NP problems, noninteractive statistical and perfect zero knowledge, the connection between noninteractive zero knowledge proof system, interactive zero knowledge proof system, and zap, and the specific applications of noninteractive zero knowledge proof system. This paper also points out the future research directions.


2005 ◽  
Vol 19 (3) ◽  
pp. 247-260 ◽  
Author(s):  
Robert J. Meyers ◽  
Michael Villanueva ◽  
Jane Ellen Smith

This article provides an overview of 2 closely linked treatment approaches for the substance abusing client: The Community Reinforcement Approach (CRA) and Community Reinforcement and Family Training (CRAFT). In 1973, Hunt and Azrin created CRA in an attempt to restructure an individual’s “community” so that a sober lifestyle was more rewarding than one dominated by alcohol. One salient CRA premise was that an individual’s substance abuse recovery was heavily influenced by his or her social and occupational environment. Sisson and Azrin (1986) later built upon this premise in their work with a new type of client; the loved one of an alcoholic individual who refused to enter treatment. This program was an early version of CRAFT, which is an intervention that works through a nonusing individual to affect the behavior of a substance abuser. This article provides an empirical review of the evolution of these 2 interventions, including their application to illicit drug using clients. It also outlines the clinical procedures that comprise CRA and CRAFT, and considers future research directions.


2012 ◽  
Vol 550-553 ◽  
pp. 284-291
Author(s):  
Ya Hong Li ◽  
Yu Qin Zhu

Unsupported MoS2hydrodesulfurization(HDS) catalysts is sulfide in its original state, so there is no need to add toxic sulfur compounds to presulfurize the hydrogenation catalyst, which has ultra-high capacity to HDS and causing attentions. This paper focuses on summarizing the preparation, characterization and desulfurization mechanism of unsupported nano MoS2catalyst and provides its future research directions.


2021 ◽  
Vol 11 (12) ◽  
pp. 5725
Author(s):  
Anbesh Jamwal ◽  
Rajeev Agrawal ◽  
Monica Sharma ◽  
Antonio Giallanza

Recent developments in manufacturing processes and automation have led to the new industrial revolution termed “Industry 4.0”. Industry 4.0 can be considered as a broad domain which includes: data management, manufacturing competitiveness, production processes and efficiency. The term Industry 4.0 includes a variety of key enabling technologies i.e., cyber physical systems, Internet of Things, artificial intelligence, big data analytics and digital twins which can be considered as the major contributors to automated and digital manufacturing environments. Sustainability can be considered as the core of business strategy which is highlighted in the United Nations (UN) Sustainability 2030 agenda and includes smart manufacturing, energy efficient buildings and low-impact industrialization. Industry 4.0 technologies help to achieve sustainability in business practices. However, very limited studies reported about the extensive reviews on these two research areas. This study uses a systematic literature review approach to find out the current research progress and future research potential of Industry 4.0 technologies to achieve manufacturing sustainability. The role and impact of different Industry 4.0 technologies for manufacturing sustainability is discussed in detail. The findings of this study provide new research scopes and future research directions in different research areas of Industry 4.0 which will be valuable for industry and academia in order to achieve manufacturing sustainability with Industry 4.0 technologies.


2012 ◽  
Vol 182-183 ◽  
pp. 369-373
Author(s):  
Tao Zhu ◽  
Hai Rong Li ◽  
Yan Dong Wan ◽  
Sha Chen ◽  
Hai Bing Liu

In view of the toxicology and hazardous nature of the submicron particles, it is paid more and more attentions of the domestic and foreign research scholars. In this paper, we introduce the research progress on recognition, attributed and formation mechanism of submicron particles in the world. Simultaneously, the controlling technologies of submicron particles are discussed. The application tendency and the existence problems of the controlling technologies are analyzed. At last, the future research directions are put forward for submicron particles control.


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