Investigation of the Effects of Probiotics on Sub-Chronic Neonicotinoid Toxicity in Rats

Agronomy ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2003
Author(s):  
Cigdem Sevim ◽  
Erol Akpinar ◽  
Aristides Tsatsakis ◽  
Serkan Yildirim ◽  
Manolis Tzatzarakis ◽  
...  
Keyword(s):  
Pesticide Residues ◽  
Dietary Supplementation ◽  
Saccharomyces Boulardii ◽  
Environmental Toxins ◽  
Toxic Effects ◽  
Health Issues ◽  
Positive Effects ◽  
Beneficial Insects ◽  
Probiotic Yeast ◽  
Metabolic Properties

Probiotics have been shown to have positive effects when it comes to combating various health issues when consumed, preventing even the absorption of environmental toxins. One of the main environmental toxins encountered today is pesticide residues. Neonicotinoids, widely applied today in countries that have approved of them, are a known class of insecticides with an excellent and effective potency. Neonicotinoids have been shown to cause various toxic effects, either acutely or chronically, on human health and on beneficial insects when exposed. To clarify the assumption that probiotics could counteract these toxic effects, especially on vital organs, the probiotic yeast “Saccharomyces boulardii” (S. boulardii) was tested against the neonicotinoids, acetamiprid (ACE) and imidacloprid (IMI), as it has outstanding physiological and metabolic properties. The results obtained from the studies indicated that although ACE and IMI induced liver, kidney, brain and bowel damage, there was a considerable level of protection by the dietary supplementation of S. boulardii, as it reduced the absorption of these insecticides.

Kluyveromyces marxianus as a Probiotic Yeast: A Mini-review

2020 ◽  
Vol 16 (8) ◽  
pp. 1163-1169
Author(s):  
Aziz Homayouni-Rad ◽  
Aslan Azizi ◽  
Parvin Oroojzadeh ◽  
Hadi Pourjafar
Keyword(s):  
Kluyveromyces Marxianus ◽  
Yeast Species ◽  
Human Life ◽  
Saccharomyces Boulardii ◽  
Biotechnological Products ◽  
Probiotic Yeast ◽  
Ancient Times ◽  
Main Components ◽  
Micro Organisms ◽  
Harmful Effects

Background: Yeasts play diverse roles in human life. Since ancient times, these micro organisms have been used to produce food products and beverages including bread and beer. Nowadays, the biotechnological products of yeast are some of the main components of commercial products. Objective: Some species of yeast such as Saccharomyces cerevisiae and Saccharomyces boulardii are recognized as probiotic yeast with extensive applications in the food and drug industries. However, certain species like Kluyveromyces marxianus are still not recognized as probiotic micro organisms despite their widespread industrial usage. In this study, the application of K. marxianus in preparing food and the medicinal product was reviewed in terms of its beneficial or harmful effects. Methods: Pub Med, Google Scholar, Scopus, and Science Direct databases were searched by using “Probiotics”, “Yeast”, and “Kluyveromyces marxianus”. Results: The findings suggest that K. marxianus can be recognized as a probiotic yeast species. Conclusion: It can be concluded that K. marxianus may be considered as a probiotic micro organism with a variety of commercial and medical applications.

scholarly journals In Vitro Bile Salt Hydrolase (BSH) Activity Screening of Different Probiotic Microorganisms

Foods ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 674
Author(s):  
Jimmy G. Hernández-Gómez ◽  
Argelia López-Bonilla ◽  
Gabriela Trejo-Tapia ◽  
Sandra V. Ávila-Reyes ◽  
Antonio R. Jiménez-Aparicio ◽  
...  
Keyword(s):  
Bile Salt ◽  
High Performance ◽  
Probiotic Strain ◽  
Saccharomyces Boulardii ◽  
Bile Salt Hydrolase ◽  
Sodium Glycocholate ◽  
Probiotic Yeast ◽  
Probiotic Strains ◽  
Bsh Activity

Bile salt hydrolase (BSH) activity in probiotic strains is usually correlated with the ability to lower serum cholesterol levels in hypercholesterolemic patients. The objective of this study was the evaluation of BSH in five probiotic strains of lactic acid bacteria (LAB) and a probiotic yeast. The activity was assessed using a qualitative direct plate test and a quantitative high-performance thin- layer chromatography assay. The six strains differed in their BSH substrate preference and activity. Lactobacillus plantarum DGIA1, a potentially probiotic strain isolated from a double cream cheese from Chiapas, Mexico, showed excellent deconjugation activities in the four tested bile acids (69, 100, 81, and 92% for sodium glycocholate, glycodeoxycholate, taurocholate, and taurodeoxycholate, respectively). In the case of the commercial probiotic yeast Saccharomyces boulardii, the deconjugation activities were good against sodium glycodeoxycholate, taurocholate, and taurodeoxycholate (100, 57, and 63%, respectively). These last two results are part of the novelty of the work. A weak deconjugative activity (5%) was observed in the case of sodium glycocholate. This is the first time that the BSH activity has been detected in this yeast.

scholarly journals In Vitro Probitotic Evaluation of Saccharomyces boulardii with Antimicrobial Spectrum in a Caenorhabditis elegans Model

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1428
Author(s):  
Ramachandran Chelliah ◽  
Eun-Ji Kim ◽  
Eric Banan-Mwine Daliri ◽  
Usha Antony ◽  
Deog-Hwan Oh
Keyword(s):  
Pancreatic Enzyme ◽  
Saccharomyces Boulardii ◽  
Antimicrobial Spectrum ◽  
Antimicrobial Efficiency ◽  
Heat Stable ◽  
Yeast Strains ◽  
Probiotic Yeast ◽  
Probiotic Strains

In the present study, we screened for potential probiotic yeast that could survive under extreme frozen conditions. The antimicrobial and heat-stable properties of the isolated yeast strains Saccharomyces boulardii (S. boulardii) (KT000032, KT000033, KT000034, KT000035, KT000036, and KT000037) was analyzed and compared with commercial probiotic strains. The results revealed that the tested S. boulardii KT000032 strain showed higher resistance to gastric enzymes (bile salts, pepsin, and pancreatic enzyme) at low pH, with broad antibiotic resistance. In addition, the strain also showed efficient auto-aggregation and co-aggregation abilities and efficient hydrophobicity in the in-vitro and in-vivo C. elegens gut model. Further, the KT000032 strain showed higher antimicrobial efficiency against 13 different enteropathogens and exhibited commensal relationships with five commercial probiotic strains. Besides, the bioactive compounds produced in the cell-free supernatant of probiotic yeast showed thermo-tolerance (95 °C for two hours). Furthermore, the thermo-stable property of the strains will facilitate their incorporation into ready-to-eat food products under extreme food processing conditions.

scholarly journals Pesticide residue in fishes from Rangpur

2016 ◽  
Vol 44 (1) ◽  
pp. 1-8
Author(s):  
Maria Zaman ◽  
Nasim Sultana ◽  
Mozaffar Husain ◽  
M Niamul Naser
Keyword(s):  
Public Health ◽  
Ethyl Acetate ◽  
Sulphuric Acid ◽  
Food Chain ◽  
Pesticide Residues ◽  
Organic Pollutant ◽  
Health Issues ◽  
Gas Chromatograph ◽  
Fish Samples ◽  
Northwestern Bangladesh

Pesticide residues, specially the persistent organic pollutant (POP) were analyzed from some fish species of Rangpur floodplain, Bangladesh. Fish samples were extracted with ethyl acetate, cleaned by sulphuric acid and analyzed by gas chromatograph and gas chromatograph-mass spectrometer. Presence of endrin was detected in Taki fish (Channa punctatus) samples. Traces of other pesticides were also evident. This confirms the use of banned pesticide in the northwestern Bangladesh. We discussed some consequences of public health issues if these contaminantspasses through in the higher food chain from the wetland ecosystem.Bangladesh J. Zool. 44(1): 1-8, 2016

scholarly journals PUFA Supplementation and Heart Failure: Effects on Fibrosis and Cardiac Remodeling

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2965
Author(s):  
Francesca Oppedisano ◽  
Rocco Mollace ◽  
Annamaria Tavernese ◽  
Micaela Gliozzi ◽  
Vincenzo Musolino ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Remodeling ◽  
Dietary Supplementation ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Related Factor ◽  
Ventricular Ejection Fraction ◽  
Pufa Supplementation ◽  
Positive Effects ◽  
Mitral Annulus Velocity

Heart failure (HF) characterized by cardiac remodeling is a condition in which inflammation and fibrosis play a key role. Dietary supplementation with n-3 polyunsaturated fatty acids (PUFAs) seems to produce good results. In fact, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have anti-inflammatory and antioxidant properties and different cardioprotective mechanisms. In particular, following their interaction with the nuclear factor erythropoietin 2 related factor 2 (NRF2), the free fatty acid receptor 4 (Ffar4) receptor, or the G-protein coupled receptor 120 (GPR120) fibroblast receptors, they inhibit cardiac fibrosis and protect the heart from HF onset. Furthermore, n-3 PUFAs increase the left ventricular ejection fraction (LVEF), reduce global longitudinal deformation, E/e ratio (early ventricular filling and early mitral annulus velocity), soluble interleukin-1 receptor-like 1 (sST2) and high-sensitive C Reactive protein (hsCRP) levels, and increase flow-mediated dilation. Moreover, lower levels of brain natriuretic peptide (BNP) and serum norepinephrine (sNE) are reported and have a positive effect on cardiac hemodynamics. In addition, they reduce cardiac remodeling and inflammation by protecting patients from HF onset after myocardial infarction (MI). The positive effects of PUFA supplementation are associated with treatment duration and a daily dosage of 1–2 g. Therefore, both the European Society of Cardiology (ESC) and the American College of Cardiology/American Heart Association (ACC/AHA) define dietary supplementation with n-3 PUFAs as an effective therapy for reducing the risk of hospitalization and death in HF patients. In this review, we seek to highlight the most recent studies related to the effect of PUFA supplementation in HF. For that purpose, a PubMed literature survey was conducted with a focus on various in vitro and in vivo studies and clinical trials from 2015 to 2021.

scholarly journals Characterization of the Probiotic Yeast Saccharomyces boulardii in the Healthy Mucosal Immune System

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153351 ◽  
Author(s):  
Lauren E. Hudson ◽  
Courtney D. McDermott ◽  
Taryn P. Stewart ◽  
William H. Hudson ◽  
Daniel Rios ◽  
...  
Keyword(s):  
Immune System ◽  
Saccharomyces Boulardii ◽  
Mucosal Immune System ◽  
Probiotic Yeast

NEW FOOD PRODUCTS WITH PROBIOTIC YEAST

2021 ◽  
Vol 1 (19) ◽  
pp. 314-316
Author(s):  
A.G. Khramtsov ◽  
S.N. Sazanova
Keyword(s):  
Ice Cream ◽  
Food Products ◽  
Saccharomyces Boulardii ◽  
Functional Ingredients ◽  
Probiotic Yeast

Saccharomycete yeast can be an alternative to traditional probiotics. The beneficial properties of Saccharomyces boulardii are well understood. By adding this yeast to food products, you can enrich them with functional ingredients. A method for producing ice cream with probiotic yeast has been developed.

scholarly journals Effect of pyrroloquinoline quinone disodium in female rats during gestating and lactating on reproductive performance and the intestinal barrier functions in the progeny

2019 ◽  
Vol 121 (7) ◽  
pp. 818-830 ◽  
Author(s):  
Boru Zhang ◽  
Wei Yang ◽  
Hongyun Zhang ◽  
Shiqi He ◽  
Qingwei Meng ◽  
...  
Keyword(s):  
Reproductive Performance ◽  
Intestinal Barrier ◽  
Dietary Supplementation ◽  
Pyrroloquinoline Quinone ◽  
Female Rats ◽  
Jejunal Mucosa ◽  
Solute Carrier Family ◽  
Barrier Functions ◽  
Positive Effects ◽  
Solute Carrier

AbstractThe objective of this study was to investigate the effects of dietary pyrroloquinoline quinone disodium (PQQ·Na2) supplementation on the reproductive performance and intestinal barrier functions of gestating and lactating female Sprague–Dawley (SD) rats and their offspring. Dietary supplementation with PQQ·Na2increased the number of implanted embryos per litter during gestation and lactation at GD 20 and increased the number of viable fetuses per litter, and the weight of uterine horns with fetuses increased at 1 d of newborn. The mRNA expression levels of catalase (CAT), glutathione peroxidase (GPx2), superoxide dismutase (SOD1), solute carrier family 2 member 1 (Slc2a1) and solute carrier family 2 member 3 (Slc2a3) in the placenta were increased with dietary PQQ·Na2supplementation. Dietary supplementation with PQQ·Na2in gestating and lactating rats increased the CAT, SOD and GPx activities of the jejunal mucosa of weaned rats on PD 21. Dietary supplementation with PQQ·Na2in female rats affected the expression of tight junction proteins (claudin, zonula occludens-1(ZO-1) andoccludin) in the jejunal mucosa of their offspring by increasing the expression ofZO-1mRNA in the expression ofZO-1and claudin mRNA in the jejunal mucosa of weaned rats on PD 21. In conclusion, dietary supplementation with PQQ·Na2in gestating and lactating female rats had positive effects on their reproductive performance and on the intestinal barrier of weaned rats.

scholarly journals Dietary cadmium chloride impairs shell biomineralization by disrupting the metabolism of the eggshell gland in laying hens

2020 ◽  
Vol 98 (2) ◽  
Author(s):  
Mingkun Zhu ◽  
Huaiyu Li ◽  
Liping Miao ◽  
Lanlan Li ◽  
Xinyang Dong ◽  
...  
Keyword(s):  
Laying Hens ◽  
Egg Quality ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Complement C3 ◽  
Mrna Levels ◽  
Palisade Layer ◽  
Positive Effects ◽  
Laying Performance ◽  
Dietary Cadmium

Abstract In this study, we identified cadmium (Cd) as a potential endocrine disruptor that impairs laying performance, egg quality, and eggshell deposition and induces oxidative stress and inflammation in the eggshell glands of laying hens. A total of 480 38-wk-old laying hens were randomly assigned into 5 groups that were fed a basal diet (control) or a basal diet supplemented with Cd (provided as CdCl2·2.5 H2O) at 7.5, 15, 30, and 60 mg Cd per kg feed for 9 wk. The results showed that, when compared with the control group, a low dose of dietary Cd (7.5 mg/kg) had positive effects on egg quality by improving albumen height, Haugh unit, yolk color, and shell thickness at the third or ninth week. However, with the increase in the dose and duration of Cd exposure, the laying performance, egg quality, and activities of eggshell gland antioxidant enzymes (catalase [CAT], glutathione peroxide [GSH-Px]), and ATPase (Na+/K+-ATPase, Ca2+-ATPase, and Mg2+-ATPase) deteriorated, and the activity of total nitric oxide synthase (T-NOS) and the level of malondialdehyde (MDA) increased significantly (P < 0.05). The histopathology and real-time quantitative PCR results showed that Cd induced endometrial epithelial cell proliferation accompanied by upregulation of the mRNA levels of progesterone receptor (PgR) and epidermal growth factor receptor (EGFR), downregulation of the mRNA levels of estrogen receptor α (ERα) and interleukin 6 (IL6), and inflammation of the eggshell gland accompanied by significantly increased expression of complement C3 and pro-inflammatory cytokine tumor necrosis factor α (TNFα) (P < 0.05). In addition, the ultrastructure of the eggshell showed that dietary supplementation with 7.5 mg/kg Cd increased the palisade layer and total thickness of the shell, but with the increase in dietary Cd supplementation (30 and 60 mg/kg) the thickness of the palisade layer and mammillary layer decreased significantly (P < 0.05), and the outer surface of the eggshell became rougher. Correspondingly, the expression of calbindin 1 (CALB1), ovocalyxin-32 (OCX-32), ovocalyxin-36 (OCX-36), osteopontin (SPP1), and ovocledidin-17 (OC-17) decreased significantly (P < 0.05) with increasing dietary Cd supplementation. Conclusively, the present study demonstrates that dietary supplementation with Cd negatively affects laying performance, egg quality, and eggshell deposition by disturbing the metabolism of eggshell glands in laying hens but has a positive effect on egg quality at low doses.

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