scholarly journals Parturition in Mammals: Animal Models, Pain and Distress

Animals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2960
Author(s):  
Julio Martínez-Burnes ◽  
Ramon Muns ◽  
Hugo Barrios-García ◽  
Dina Villanueva-García ◽  
Adriana Domínguez-Oliva ◽  
...  

Parturition is a complex physiological process and involves many hormonal, morphological, physiological, and behavioural changes. Labour is a crucial moment for numerous species and is usually the most painful experience in females. Contrary to the extensive research in humans, there are limited pain studies associated with the birth process in domestic animals. Nonetheless, awareness of parturition has increased among the public, owners, and the scientific community during recent years. Dystocia is a significant factor that increases the level of parturition pain. It is considered less common in polytocous species because newborns’ number and small size might lead to the belief that the parturition process is less painful than in monotocous animal species and humans. This review aims to provide elements of the current knowledge about human labour pain (monotocous species), the relevant contribution of the rat model to human labour pain, and the current clinical and experimental knowledge of parturition pain mechanisms in domestic animals that support the fact that domestic polytocous species also experience pain. Moreover, both for women and domestic animal species, parturition’s pain represents a potential welfare concern, and information on pain indicators and the appropriate analgesic therapy are discussed.

1979 ◽  
Vol 83 (3) ◽  
pp. 539-545 ◽  
Author(s):  
M. Eisa ◽  
A. E. Karrar ◽  
A. H. Abd Elrahim

To determine the presence and prevalence of bluetongue (BT) infection in a variety of domestic animal species in different geographical regions of the Sudan, a serological study using the agar gel precipitation technique was initiated. A total of 2142 serum samples were examined. Of the numbers tested approximately 28% of sheep, 11.2% of goats, 8% of cattle and 4.9% of camels were positive for group-specific antibodies to BT virus antigen, indicating previous exposure to BT infection. None of the samples tested from horses or donkeys were positive. The findings suggest that the disease is widely distributed in most parts of the Sudan where possible insect vectors prevail and may be endemic in sheep in Juba District, Equatoria Province, Southern Region. Goats appeared to have some degree of resistance to infection compared with sheep, and there seemed to be no significant differences in positive rates between farm and free-range cattle.It is concluded that BT infection may cause clinical disease in sheep, while it is probably subclinical or inapparent in goats, cattle and camels of the Sudan.


1999 ◽  
Vol 23 (1) ◽  
pp. 113-123
Author(s):  
R. Y. AL-Kubaisee ◽  
M. J. Alwan ◽  
B. AL- Kaisee

Out of 1250 bovine fasciolliasis. 10 cattle were found to have lung fascioliasis, one cow had abomasal fascioliasis and another one wih renal fascioliasis.  The recovered flukes were identified as immature spec imens of Fassciola gigantica .Gross and histopathology of the lesions were studied. The occurrence of Fasciola gigantica in kideny and abomasum was recorded for the first time :  Introduction Infection with Fasciola gigantica is an important cause of disease and economic loss in domestic animals in many parts of the world. Among the effects attributed 10 flucke infection are loss of condition , reduced meat and milk production reduced fertility and rendering of livers unsuitable for human consumpiior. . Severe infection may cause death either directly or indirecily by inzitiating or aggravating bacterial infection (1). One of the reasons making F.gigantica more pathogenic ihan F.hepatica is frequent ecotopic occurence of F.gigantica in most of the domestic animal species (1,2,3). Ectopic ovine F.gigantica infection was reported in spleen, lung, heart, diphragm and portal vein, in additional the liver (4,5). In cattle F.hepatica_ could only produce lesions in the liver but F.gigantica extended its pathogenic effects to the lung tissue (3,6).  The aim of this study is to elucidate the occurence of F.gigantica in organs other than the liver with parasitological and pathological investigation. 


2011 ◽  
Vol 2011 ◽  
pp. 1-14 ◽  
Author(s):  
Christophe Casteleyn ◽  
Sofie Breugelmans ◽  
Paul Simoens ◽  
Wim Van den Broeck

This paper gives an overview of the anatomical localization and histological characteristics of the tonsils that are present in ten conventional domestic animal species, including the sheep, goat, ox, pig, horse, dog, cat, rabbit, rat, and pigeon. Anatomical macrographs and histological images of the tonsils are shown. Six tonsils can be present in domestic animals, that is, the lingual, palatine, paraepiglottic, pharyngeal, and tubal tonsils and the tonsil of the soft palate. Only in the sheep and goat, all six tonsils are present. Proper tonsils are absent in the rat, and pigeon. In the rabbit, only the palatine tonsils can be noticed, whereas the pig does not present palatine tonsils. The paraepiglottic tonsils lack in the ox, horse, and dog. In addition, the dog and cat are devoid of the tubal tonsil and the tonsil of the soft palate.


2019 ◽  
Vol 14 (7) ◽  
pp. 598-606
Author(s):  
Sarah Albogami

Background:: Regeneration is the process by which body parts lost as a result of injury are replaced, as observed in certain animal species. The root of regenerative differences between organisms is still not very well understood; if regeneration merely recycles developmental pathways in the adult form, why can some animals regrow organs whereas others cannot? In the regulation of the regeneration process as well as other biological phenomena, epigenetics plays an essential role. Objective:: This review aims to demonstrate the role of epigenetic regulators in determining regenerative capacity. Results:: In this review, we discuss the basis of regenerative differences between organisms. In addition, we present the current knowledge on the role of epigenetic regulation in regeneration, including DNA methylation, histone modification, lysine methylation, lysine methyltransferases, and the SET1 family. Conclusion:: An improved understanding of the regeneration process and the epigenetic regulation thereof through the study of regeneration in highly regenerative species will help in the field of regenerative medicine in future.


2020 ◽  
Vol 21 (20) ◽  
pp. 7697 ◽  
Author(s):  
Malvina Koni ◽  
Veronica Pinnarò ◽  
Maria Felice Brizzi

Cancer is one of the greatest public health challenges. According to the World Health Organization (WHO), 9.6 million cancer deaths have been reported in 2018. The most common cancers include lung, breast, colorectal, prostate, skin (non-melanoma) and stomach cancer. The unbalance of physiological signalling pathways due to the acquisition of mutations in tumour cells is considered the most common cancer driver. The Wingless-related integration site (Wnt)/β-catenin pathway is crucial for tissue development and homeostasis in all animal species and its dysregulation is one of the most relevant events linked to cancer development and dissemination. The canonical and the non-canonical Wnt/β-catenin pathways are known to control both physiological and pathological processes, including cancer. Herein, the impact of the Wnt/β-catenin cascade in driving cancers from different origin has been examined. Finally, based on the impact of Extracellular Vesicles (EVs) on tumour growth, invasion and chemoresistance, and their role as tumour diagnostic and prognostic tools, an overview of the current knowledge linking EVs to the Wnt/β-catenin pathway is also discussed.


2018 ◽  
Vol 5 (4) ◽  
pp. 92 ◽  
Author(s):  
Kathryn Huyvaert ◽  
Robin Russell ◽  
Kelly Patyk ◽  
Meggan Craft ◽  
Paul Cross ◽  
...  

Diseases that affect both wild and domestic animals can be particularly difficult to prevent, predict, mitigate, and control. Such multi-host diseases can have devastating economic impacts on domestic animal producers and can present significant challenges to wildlife populations, particularly for populations of conservation concern. Few mathematical models exist that capture the complexities of these multi-host pathogens, yet the development of such models would allow us to estimate and compare the potential effectiveness of management actions for mitigating or suppressing disease in wildlife and/or livestock host populations. We conducted a workshop in March 2014 to identify the challenges associated with developing models of pathogen transmission across the wildlife-livestock interface. The development of mathematical models of pathogen transmission at this interface is hampered by the difficulties associated with describing the host-pathogen systems, including: (1) the identity of wildlife hosts, their distributions, and movement patterns; (2) the pathogen transmission pathways between wildlife and domestic animals; (3) the effects of the disease and concomitant mitigation efforts on wild and domestic animal populations; and (4) barriers to communication between sectors. To promote the development of mathematical models of transmission at this interface, we recommend further integration of modern quantitative techniques and improvement of communication among wildlife biologists, mathematical modelers, veterinary medicine professionals, producers, and other stakeholders concerned with the consequences of pathogen transmission at this important, yet poorly understood, interface.


2021 ◽  
pp. 190-195
Author(s):  
Pushkar Pal ◽  
Adisorn Yawongsa ◽  
Rajesh Bhatta ◽  
Hiroshi Shimoda ◽  
Theera Rukkwamsuk

Background and Aim: Animal rabies is endemic in Nepal, and it occurs in two forms. Although governmental and non-governmental agencies are working toward the control of rabies by mass dog vaccination and stray dog population management, there is still massive number of rabies incidence reported to the reference veterinary laboratory, Nepal. Therefore, this study aimed to assess animal species, temporal, regional, and agro-ecological distribution patterns of animal rabies in Nepal from 2005 to 2017. Materials and Methods: The epidemiological data on animal rabies from the period of 2005 to 2017 were obtained from the Central Veterinary Laboratory, Tripureshwor, Kathmandu, Nepal. The laboratory-confirmed rabies cases were analyzed according to animal species, temporal, regional (developmental zones), and agro-ecological distributions. In addition, descriptive statistics were used to evaluate the distribution patterns of rabies. Results: From 2005 to 2017, a total of 2771 suspected rabies cases in animals were reported to The Central Veterinary Hospital, Kathmandu. Of which, 1302 were found laboratory-confirmed cases. The rabies cases were most commonly reported and confirmed in dogs followed by other domestic animals. The high occurrences were recorded between 2005 and 2007. However, the incidence was increased during 2016 and 2017. The highest number of rabies cases was recorded in the eastern development zone, and the least number in the central zone at regional level. Likewise, it was highest in the Terai (plain) region and lowest in mountainous areas at agro-ecological zones. The findings also revealed that the occurrences of rabies significantly differed among seasons. Conclusion: Rabies is present in Nepal throughout the year and all seasons with seasonal variation. Among the animal species, dogs are the primary animals affected with rabies followed by cattle and other domestic animals. At the regional level, eastern development zone had the highest incidence and Central development zone recorded the least. Similarly, the Terai region had the highest incidence rates, and the least overall prevalence rate was observed in mountainous regions among agro-ecological zones. Therefore, the government should implement the strict enforcement of mass dog vaccination and dog population management through one health approach to control rabies incidence in the country.


2020 ◽  
Vol 20 (1) ◽  
pp. 2-11
Author(s):  
Nilsen Aparecida Vieira Marcondes

Objetiva-se discutir neste breve intróito retrospectivo de revisão de normatizações constitucionais pátrias a tutela do animal doméstico. Esta síntese reflexiva sobre a tutela do animal doméstico brasileiro no âmbito constitucional se apresenta quanto à forma de abordagem do assunto, como qualitativo, no que tange a modalidade investigativa como básico, do ponto de vista de seus objetivos, como descritivo, com relação aos procedimentos técnicos, qualifica-se como documental e bibliográfico. Conclui-se que os delineamentos, os limites, bem como os avanços na conquista da tutela animal e consequentemente do animal doméstico demonstram o quanto o reconhecimento de tal questão é socialmente construído. Além disso, a expansão, a solidificação e o desenvolvimento contínuo também da vida humana e da sociedade implicam necessariamente na preservação e na ampliação de acesso um direito fundamental nominalmente reconhecido pela Constituição Federal de 1988 como direito ao ambiente ecologicamente equilibrado no qual se insere evidentemente a fauna, ou seja, os animais domésticos, domesticados, silvestres e exóticos. Palavras-chave: Animal Doméstico. Tutela. Constituições Federais. Brasil.  AbstractThe objective of this brief retrospective introjective review of constitutional norms is to discuss the protection of domestic animals. This reflexive synthesis about the protection of the Brazilian domestic animal in the constitutional scope presents itself as to the way of approaching the subject, as qualitative, in what refers to the research modality as basic, from the point of view of its objectives, as descriptive, with respect to the procedures technicians, qualifies as documentary and bibliographical. It is concluded that the delineations, the limits, as well as the advances in the conquest of the animal guardianship and consequently of the domestic animal demonstrate how much the recognition of such question is socially constructed. In addition, the expansion, solidification and continuous development of human life and society necessarily imply the preservation and expansion of access to a fundamental right nominally recognized by the Federal Constitution of 1988 as a right to an environmentally balanced environment in which the animal, domesticated, wild and exotic animals. Keywords: Domestic Animals. Guardianship. Federal Constitutions. Brasil.


2013 ◽  
Vol 18 (18) ◽  
Author(s):  
S Tsiodras ◽  
G Dougas ◽  
A Baka ◽  
C Billinis ◽  
S Doudounakis ◽  
...  

Greece has been rabies-free since 1987 with no human cases since 1970. During 2012 to 2013, rabies has re-emerged in wild and domestic animals in northern Greece. By end March 2013, rabies was diagnosed in 17 animals including 14 red foxes, two shepherd dogs and one cat; 104 subsequent human exposures required post-exposure prophylaxis according to the World Health Organization criteria. Human exposures occurred within 50 km radius of a confirmed rabies case in a wild or domestic animal, and most frequently stray dogs were involved.


Genes ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 1009 ◽  
Author(s):  
Saqib Umer ◽  
Shan Jiang Zhao ◽  
Abdul Sammad ◽  
Bahlibi Weldegebriall Sahlu ◽  
YunWei Pang ◽  
...  

Anti-Müllerian hormone (AMH) is a reliable and easily detectable reproductive marker for the fertility competence of many farm animal species. AMH is also a good predictor of superovulation in cattle, sheep, and mares. In this review, we have summarized the recent findings related to AMH and its predictive reliability related to fertility and superovulation in domestic animals, especially in cattle. We focused on: (1) the dynamics of AMH level from infancy to prepubescence as well as during puberty and adulthood; (2) AMH as a predictor of fertility; (3) the association between antral follicle count (AFC) and plasma AMH level; (4) AMH as a predictor of superovulation; and (5) factors affecting AMH levels in domestic animals, especially cattle. Many factors affect the circulatory levels of AMH when considering the plasma, like nutrition, activity of granulosa cells, disease state and endocrine disruptions during fetal life. Briefly, we concluded that AMH concentrations are static within individuals, and collection of a single dose of blood has become more popular in the field of assisted reproductive technologies (ART). It may act as a potential predictor of fertility, superovulation, and ovarian disorders in domestic animals. However, due to the limited research in domestic animals, this potential of AMH remains underutilized.


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