scholarly journals Platelet-Rich Fibrin: A Viable Therapy for Endodontic-Periodontal Lesions? A Preliminary Assessment

2021 ◽  
Vol 11 (15) ◽  
pp. 7081
Author(s):  
Maria Ioana Onicas ◽  
Laura Elena Narita ◽  
Alexandru Mester ◽  
Florin Onisor ◽  
Leonardo Mancini

Background and Objectives: The endodontic system and the periodontium are closely interrelated and the infection of both leads to the appearance of endodontic-periodontal lesions. Along with the endodontic and periodontal classic treatment, in most cases, there is a need for regenerative periodontal therapy for the repair of the damaged tissue. One material that stimulates bone healing is represented by platelet-rich fibrin (PRF). The aim of this study was to determine if the inclusion of PRF in the treatment protocol of endodontic-periodontal lesions is effective. Materials and Methods: This review was conducted according to the PRISMA guidelines. Four databases, MEDLINE (through PubMed), Scopus, Web of Science, and Google Scholar, were used in order to find all significant articles on the topic. Relevant keywords were used in different combinations. Results: The inclusion criteria were met by six studies, published between 2014 and 2020 and they were selected for the review. The use of PRF for the regenerative therapy of endodontic-periodontal lesions showed favorable outcomes in all of the studies included, with significant reductions in the probing depths. Conclusion: While platelet-rich fibrin may be beneficial, further research is needed.

Author(s):  
Ana Marchena-Rodriguez ◽  
Ana Belen Ortega-Avila ◽  
Pablo Cervera-Garvi ◽  
David Cabello-Manrique ◽  
Gabriel Gijon-Nogueron

Objective: Our study aim is to identify and describe the definitions used for different types of running shoes. In addition, we highlight the existence of gaps in these concepts and propose possible new approaches. Methods: This review was undertaken in line with the guidelines proposed by Green et al., based on a literature search (until December 2019) of the PubMed, Web of Science, Scopus, SPORTDiscus and Google Scholar databases. A total of 23 papers met the inclusion criteria applied to identify the definition of running shoes. Results: Although there is a certain consensus on the characteristics of minimalist footwear, it is also described by other terms, such as barefoot-style or barefoot-simulating. Diverse terms are also used to describe other types of footwear, and in these cases, there is little or no consensus regarding their characteristics. Conclusions: The terms barefoot-simulated footwear, barefoot-style footwear, lightweight shoes and full minimalist shoes are all used to describe minimalist footwear. The expressions partial minimalist, uncushioned minimalist and transition shoes are used to describe footwear with non-consensual characteristics. Finally, labels such as shod shoes, standard cushioned running shoes, modern shoes, neutral protective running shoes, conventional, standardised, stability style or motion control shoes span a large group of footwear styles presenting different properties.


2019 ◽  
Vol 24 ◽  
Author(s):  
Josimar Antônio de Alcântara Mendes ◽  
Thomas Ormerod

The best interests of the child (BIC) should be of primary consideration in any situation involving children. Thus, BIC is commonly adopted as a principle, doctrine or test to weight decision-making regarding children. This study consists of an integrative literature review of English and Portuguese publications aimed at investigating how various studies address BIC definitions, characteristics and applications. The inclusion criteria were: 1) articles published between 2012 and 2017, and 2) those clearly addressing a BIC definition, characteristic and/or application. The chosen English databases were ASSIA, PsychARTICLES, PsychInfo, Scopus, Web of Science and Google Scholar; the Portuguese databases were: LILACS, PePsic, Redalyc, Periódicos CAPES and Google Scholar. The main descriptor used was ‘best interests of the child’ which led to 1488 articles being found, and 14 selected. Brazilian articles have focused on the need to protect the child’s physical and psycho-socioemotional well-being, highlighting the child as a subject of rights, and maintaining child’s familial bonds. English articles have broadened the BIC perspective, highlighting the child’s idiosyncrasies, the role of the parent’s interests, and BIC as non-individualistic, flexible and complex. Other results show that BIC is largely related to the child’s development, which is divided into ‘material-physiological’ (basic needs and surviving) and ‘contextual’ (non-material and psychosocial and emotional needs) domains. Overall, BIC is a pluralistic, complex and multi-dimensional construct that depends on the child’s relational contexts.


2020 ◽  
Vol 10 (3) ◽  
pp. 116-125
Author(s):  
Thainá Ferreira Silva ◽  
Amanda Alves de Melo ◽  
Dener Lucas Araújo dos Santos ◽  
Elisa Carvalho Vaz ◽  
Leonardo Carlos Jeronimo Corvalan ◽  
...  

Objective: To perform a systematic review of articles that evaluated the scientific production on SARS-CoV-2 through bibliometric analyzes. Methods: Scopus, Web of Science and Google Scholar databases were used. After applying the pre-established inclusion criteria, 30 articles were included. Results. The total number of articles found in the bibliometric studies on SARS-CoV-2 varied widely from 153 to 21,395 articles and an average equal to 4,279 (± 5,510). A total of 17 countries published within the scope of this study, but only six published more than one article, emphasizing authors from Chinese institutions (17%). Scopus was the most used database in bibliometric studies (50%, n = 15). The articles used 72 different keywords with emphasis on: COVID-19 (15%), SARS-CoV-2 (12%) and 2019-nCoV (9%). Conclusion. We are facing an unprecedented scenario of information about SARS-CoV-2 and this has required a collective scientific effort reflected in the daily publication of hundreds of studies (articles, pre-prints, clinical guides, protocols). Bibliometric methods are being increasingly used by the scientific community to systematize this information. Therefore, the systematic review carried out in this study provided an overview of the bibliometric literature on the SARS-CoV-2 virus.


2021 ◽  
pp. 003022282110382
Author(s):  
Mohammadreza Firouzkouhi ◽  
Nasrollah Alimohammadi ◽  
Abdolghani Abdollahimohammad ◽  
Gholamreza Bagheri ◽  
Jebraeil Farzi

Families encounter some issues after the death of their loved one due to COVID-19. Therefore, this study aimed to explore the family’s views on the death of their loved one due to COVID-19. This integrative review was conducted from May to Jan 2021. We searched PubMed, Google Scholar, Scopus, Web of Science, CINHAL, Magiran, and SID databases. Fifteen studies met the inclusion criteria. The results were classified into two categories, including before and after death. The issues raised before the death of the loved ones include no visit and absence at death time, fear of being infected with the COVID-19, death anxiety, failure to perform religious rites at death, and psychological problems. The after-death issues were related to funeral, burial, rituals, prolonged grieving, maladaptation, loneliness, and repeated mourning. Therefore, health policymakers should provide support before and after the death of loved ones for families.


2020 ◽  
pp. 116-116
Author(s):  
Natasa Nikolic-Jakoba ◽  
Milena Barac ◽  
Ksenija Zelic ◽  
Arso Vukicevic ◽  
Gordana Jovicic ◽  
...  

Introduction/Objective. Finite element analysis (FEA) is mathematical method which can be used for the assessment of biomechanical behavior of dento-alveolar complex. The objective was to analyze biomechanical behavior changes of teeth and supporting tissues under occlusal load in cases of horizontal and vertical alveolar bone loss, to assess potential impact of tooth displacement and altered stress distribution on further damage, and to evaluate the impact of regenerative periodontal therapy. Methods. Three patient-specific three-dimensional-Finite-Element (3D FE) models were developed from the acquired cone beam computed tomography, comprising the patient's upper left canine, first and second premolar, and adjacent bone. Model 1 represented horizontal bone loss; Model 2 included intrabony defect along distal aspect of tooth #24. Model 3 represented situation six months after the regenerative periodontal surgery. Displacement, Von Mises, and principal stresses were evaluated through FEA, under moderate vertical occlusal load. Results. FEA demonstrated that in model with vertical bone loss significant tooth displacement was present, even though the clinically evident tooth mobility was absent. Biomechanical behavior and stress distribution of teeth and surrounding tissues under moderate occlusal load was much more altered in case with vertical bone loss in comparison with horizontal bone loss. Six months following the regenerative therapy, the values of all evaluated parameters were noticeable reduced. Conclusion. Regenerative periodontal therapy improved the biomechanical characteristics of the affected teeth and the related periodontal structures.


2019 ◽  
Vol 27 (1) ◽  
pp. 31-42
Author(s):  
Gloria Cristina Aranzazu-Moya

Background: Periodontal disease is considered as a diabetes complication and has been suggested that periodontal treatment plus antibiotics should reduce glycated hemoglobin A, by reducing local production of pro inflammatory substances. Objective: To evaluate diabetic patients with periodontal disease under periodontal treatment plus topical antibiotics and reduction of  HbA1c, compared to diabetic patients under periodontal treatment without antibiotics. Materials and Methods: Using PUBMED, SCOPUS, WEB OF SCIENCE, EMBASE and Google Scholar data bases, were screened documents from 2008 to 2018. The documents included were the clinical studies, which included non-surgical periodontal treatment plus topical antibiotics, whose outcomes included the HbA1c report. Two independent researchers evaluate title; abstract and bias risk with Downs Black scale and Cochrane tool. Documents with a score higher than 15 on average by the two evaluators were included. Results: Five articles, which find inclusion criteria, were identified. Two documents failed to demonstrate statistically significant effect when compared to non-surgical periodontal therapy alone. Conclusion: In general a modest reduction of HbA1c was identified when using antibiotic therapy.


2020 ◽  
Vol 01 ◽  
Author(s):  
Carla Pires ◽  
Ana Fernandes

Background: Natural products are commonly used for treating health problems. These products may be associated with adverse events, which are defined as "noxious and unintended response to a medicinal product" by the European Medicine Agency. Objectives: To identify studies describing at least one adverse event (or with potential to promote an adverse event) related to the use of natural products, as well as to describe the involved product(s) and adverse event(s). Methods: A pre-systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Keywords: "natural product(s)" and ["adverse drug reaction(s)" or "adverse effect(s)"]. Screened databases: PubMed, SciELO, DOAJ and Google Scholar. Inclusion criteria: papers describing at least one adverse event associated with the use of natural products and published between 2017 and 2019. Exclusion criteria: Repeated studies, reviews and papers written in other languages than English, Portuguese, French or Spanish. Results: 104 studies were identified (20 PubMed; 0 SciELO; 2 DOAJ; 82 Google Scholar), but only 10 were selected (4 PubMed and 6 Google Scholar): 1 in-vitro study; 2 non-clinical studies, 1 study reporting in-vitro and clinical data and 5 studies were cases reports. Globally, 997 reports of adverse drug reactions with natural products were identified, mainly non-severe cases. Conclusion: Since a limited number of studies was found, we conclude that adverse events due to natural products may be underreported, or natural products may have a good safety profile. This review contributes for assuring the safety of natural products consumers, by evaluating the knowledge/information on the potential adverse events and interactions of these products.


2021 ◽  
Vol 10 (13) ◽  
pp. 2862
Author(s):  
Đorđe Pojatić ◽  
Ivana Tolj ◽  
Davorin Pezerović ◽  
Dunja Degmečić

Alexithymia is a construct defined as the inability to differentiate between emotional experiences and bodily sensations. According to existing knowledge, alexithymia may have a major effect on the process of treatment and the outcome of the hemodialysis disease. The objective of this literature review was to determine the significance that alexithymia has for compliance and variables of clinical and mental health in the population of hemodialysis patients. For the above purpose, bibliographic databases “MEDLINE” and “Web of Science” were searched. The matrix method was used in analysis of articles. Searching both databases resulted in 248 articles. After applying exclusion and inclusion criteria, we included results of 13 articles in the literature review. The results of the search are findings regarding the prevalence and correlation of alexithymia with variables of clinical and mental health in hemodialysis patients. Alexithymia is significantly more common in the population of hemodialysis patients, and it has a negative effect on their mental and somatic health. Alexithymia levels in hemodialysis patients are more pronounced in cases where there is a greater number of comorbidities. Alexithymia is the predictor of high mortality rate in the population of hemodialysis patients, independent of other comorbidities.


2021 ◽  
pp. 030157422110195
Author(s):  
Ashish Agrawal ◽  
TM Chou

Introduction: The objective of this systematic review is to assess the effect of vibrational force on biomarkers for orthodontic tooth movement. Methods: An electronic search was conducted for relevant studies (up to December 31, 2020) on the following databases: Pubmed, Google scholar, Web of Science, Cochrane Library, Wiley Library, and ProQuest Dissertation Abstracts and Thesis database. Hand searching of selected orthodontic journals was also undertaken. The selected studies were assessed for the risk of bias in Cochrane collaboration risk of bias tool. The “traffic plot” and “weighted plot” risk of bias distribution are designed in the RoB 2 tool. The 2 authors extracted the data and analyzed it. Results: Six studies fulfilled the inclusion criteria. The risks of biases were high for 4, low and some concern for other 2 studies. The biomarkers, medium, device, frequency and duration of device, as well as other data were extracted. The outcomes of the studies were found to be heterogenous. Conclusion: One study showed highly statistically significant levels of IL-1 beta with <.001. Rate of tooth movement was correlated with levels of released biomarkers under the influence of vibrational force in 3 studies, but it was found to be significant only in 1 study. It was further observed that vibration does not have any significant reduction in pain and discomfort.


Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 868
Author(s):  
Jorge Lorenzo Calvo ◽  
Xueyin Fei ◽  
Raúl Domínguez ◽  
Helios Pareja-Galeano

Cognitive functions are essential in any form of exercise. Recently, interest has mounted in addressing the relationship between caffeine intake and cognitive performance during sports practice. This review examines this relationship through a structured search of the databases Medline/PubMed and Web of Science for relevant articles published in English from August 1999 to March 2020. The study followed PRISMA guidelines. Inclusion criteria were defined according to the PICOS model. The identified records reported on randomized cross-over studies in which caffeine intake (as drinks, capsules, energy bars, or gum) was compared to an identical placebo situation. There were no filters on participants’ training level, gender, or age. For the systematic review, 13 studies examining the impacts of caffeine on objective measures of cognitive performance or self-reported cognitive performance were selected. Five of these studies were also subjected to meta-analysis. After pooling data in the meta-analysis, the significant impacts of caffeine only emerged on attention, accuracy, and speed. The results of the 13 studies, nevertheless, suggest that the intake of a low/moderate dose of caffeine before and/or during exercise can improve self-reported energy, mood, and cognitive functions, such as attention; it may also improve simple reaction time, choice reaction time, memory, or fatigue, however, this may depend on the research protocols.


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