scholarly journals Dummy Molecularly Imprinted Polymers Using DNP as a Template Molecule for Explosive Sensing and Nitroaromatic Compound Discrimination

Chemosensors ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 255
Author(s):  
Anna Herrera-Chacon ◽  
Andreu Gonzalez-Calabuig ◽  
Manel del Valle
Keyword(s):  
Low Cost ◽  
Sol Gel ◽  
Modified Electrodes ◽  
Principal Component ◽  
Species Discrimination ◽  
Template Molecule ◽  
Molecularly Imprinted ◽  
Related Substances ◽  
Response Range ◽  
Potential Applications

This work reports a rapid, simple and low-cost voltammetric sensor based on a dummy molecularly imprinted polymer (MIP) that uses 2,4-dinitrophenol (DNP) as a template for the quantification of 2,4,6-trinitrotoluene (TNT) and DNP, and the identification of related substances. Once the polymer was synthesised by thermal precipitation polymerisation, it was integrated onto a graphite epoxy composite (GEC) electrode via sol–gel immobilisation. Scanning electron microscopy (SEM) was performed in order to characterise the polymer and the sensor surface. Responses towards DNP and TNT were evaluated, displaying a linear response range of 1.5 to 8.0 µmol L−1 for DNP and 1.3 to 6.5 µmol L−1 for TNT; the estimated limits of detection were 0.59 µmol L−1 and 0.29 µmol L−1, for DNP and TNT, respectively. Chemometric tools, in particular principal component analysis (PCA), demonstrated the possibilities of the MIP-modified electrodes in nitroaromatic and potential interfering species discrimination with multiple potential applications in the environmental field.

scholarly journals A simple approach to prepare fluorescent molecularly imprinted nanoparticles

RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7732-7737
Author(s):  
Fenying Wang ◽  
Dan Wang ◽  
Tingting Wang ◽  
Yu Jin ◽  
Baoping Ling ◽  
...  
Keyword(s):  
High Performance ◽  
Low Cost ◽  
Sol Gel ◽  
Silica Sol ◽  
Simple Approach ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Molecularly Imprinted Nanoparticles

Fluorescent molecularly imprinted polymer (FMIP) gains great attention in many fields due to their low cost, good biocompatibility and low toxicity. Here, a high-performance FMIP was prepared based on the autocatalytic silica sol–gel reaction.

Low Cost Integrated Sensors Utilizing Patterned Nano-Structured Titania Arrays Fabricated Using a Simple Process

2004 ◽  
Vol 828 ◽  
Author(s):  
Zuruzi Abu Samah ◽  
Andrei Kolmakov ◽  
Martin Moskovits ◽  
Noel C. MacDonald
Keyword(s):  
Photoelectron Spectroscopy ◽  
Low Cost ◽  
Sol Gel ◽  
X Ray Diffraction ◽  
Aqueous Hydrogen Peroxide ◽  
X Ray ◽  
Sensing Systems ◽  
Potential Applications ◽  
Nano Wires ◽  
Low Temperature Process

ABSTRACTUsing a novel low-temperature process, we demonstrate the facile integration of crack-free nanostructured titania (NST) as sensing elements in microsystems. Unlike conventional sol-gel methods, NST layers of interconnected nano-walls and nano-wires were formed by reacting Ti surfaces with aqueous hydrogen peroxide solution. Cracks were observed in NST layers formed on blanket Ti films but absent on arrays of patterned Ti pads below a threshold dimension. Analyses using TEM, high resolution SEM, X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) reveal that NST consists of anatase TiO2 nano-crystals. NST pads were found able to detect oxygen gas of a few ppm. NST pad arrays were integrated on rigid and flexible substrates with potential applications in low cost and wearable sensing systems.

scholarly journals Graphene Oxide-Silver Nanoparticles in Molecularly-Imprinted Hybrid Films Enabling SERS Selective Sensing

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1674 ◽  
Author(s):  
Yu Jiang ◽  
Davide Carboni ◽  
Luca Malfatti ◽  
Plinio Innocenzi
Keyword(s):  
Silver Nanoparticles ◽  
Graphene Oxide ◽  
Raman Scattering ◽  
Sol Gel ◽  
Template Molecule ◽  
Molecularly Imprinted ◽  
Raman Enhancement ◽  
The Matrix ◽  
Surface Enhanced Raman ◽  
Raman Sensor

A highly sensitive and selective Raman sensor has been developed by combining molecularly imprinted cavities, silver nanoparticles, and graphene oxide into a hybrid organic-inorganic film. The molecular imprinted nanocomposite material is an advanced platform that exhibits Graphene-mediated Surface-Enhanced Raman Scattering. The sensing layers have been prepared via sol-gel process and imprinted with rhodamine 6G to obtain selective dye recognition. Graphene oxide sheets decorated with silver nanoparticles have been incorporated into the matrix to enhance the Raman scattering signal. The template molecule can be easily removed from the films by ultrasonication in ethanol. A 712-fold Raman enhancement has been observed, which corresponds to a 2.15 × 1013 count·μmol−1 signal enhancement per molecular cavity. Besides Raman enhancement, the sensing platform has shown an excellent selectivity toward the test molecule with respect to similar dyes. In addition, the material can be reused at least 10 times without any loss of performance.

scholarly journals Development of Water-Compatible Molecularly Imprinted Polymers Based on Functionalized β-Cyclodextrin for Controlled Release of Atropine

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 130 ◽  
Author(s):  
Yahui He ◽  
Shaomei Zeng ◽  
A. M. Abd El-Aty ◽  
Ahmet Hacımüftüoğlu ◽  
Woldemariam Kalekristos Yohannes ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Molecularly Imprinted Polymers ◽  
Isotherm Models ◽  
Template Molecule ◽  
Stimuli Responsive ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Potential Applications

Herein, a novel method for molecularly imprinted polymers (MIPs) using methacrylic acid functionalized beta-cyclodextrin (MAA-β-CD) monomer is presented, which was designed as a potential water-compatible composite for the controlled release of atropine (ATP). The molecularly imprinted microspheres with pH-sensitive characteristics were fabricated using thermally-initiated precipitation polymerization, employing ATP as a template molecule. The effects of different compounds and concentrations of cross-linking agents were systematically investigated. Uniform microspheres were obtained when the ratio between ATP, MAA-β-CD, and trimethylolpropane trimethacrylate (TRIM) was 1:4:20 (mol/mol/mol) in polymerization system. The ATP loading equilibrium data was best suited to the Freundlich and Langmuir isotherm models. The in vitro drug release study was assessed under simulated oral administration conditions (pH 1.5 and 7.4). The potential usefulness of MIPs as drug delivery devices are much better than non-molecularly imprinted polymers (NIPs). The study shows that the prepared polymers are a pH stimuli-responsive system, which controlled the release of ATP, indicating the potential applications in the field of drug delivery.

Sythesis of Molecularly Imprinted Polymers for the Binding and Recognition of Nonylphenol

2013 ◽  
Vol 641-642 ◽  
pp. 55-59 ◽  
Author(s):  
Yan Jie Bi ◽  
Wen Yan Li ◽  
Chen Yuan ◽  
Bin Song Wang
Keyword(s):  
Molecularly Imprinted Polymers ◽  
High Selectivity ◽  
Sol Gel ◽  
Template Molecule ◽  
Binding Properties ◽  
Adsorption Selectivity ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Selective Enrichment ◽  
Sol Gel Process

In this paper, molecularly imprinted polymers with high selectivity for nonylphenol (NP) were synthesized by sol-gel process using 4-vinylpyridine (4-Vpy) as functional monomer, ethyleneglycol dimethacrylate as crosslinker (EGDMA), azobisisobutyronitrile (AIBN) as initiator, NP as template molecules. The performance of imprinted material was evaluated by adsorption kinetic, adsorption isotherm and adsorption selectivity. The results indicated that this material had not only binding properties but also high selectivity to the template molecule, which had good application prospects in the selective enrichment and separation of NP for pretreatment and analysis of complex environmental samples.

Superparamagnetic Magnetite Nanotubes Synthesized by Template-Assisted Sol–Gel Autocombustion

2020 ◽  
Vol 15 (11) ◽  
pp. 1381-1384
Author(s):  
Xinwei Zhang ◽  
Xuanyu Song ◽  
Huiyi Dong ◽  
Chao Zhang ◽  
Chunlei Wang
Keyword(s):  
Magnetic Measurements ◽  
Low Cost ◽  
Physical Property Measurement System ◽  
Sol Gel ◽  
Physical Property ◽  
Average Diameter ◽  
Blocking Temperature ◽  
Synthetic Process ◽  
Aspect Ratios ◽  
Potential Applications

Magnetite nanotubes with an average diameter of about 140 nm were synthesized by an AAO templateassisted sol–gel autocombustion method. The entire synthetic process is convenient, low-cost and nontoxic. The crystalline structure of the magnetite nanotubes was investigated by X-ray diffraction. From the diffraction pattern, we conclude that pure phase magnetite nanotubes were obtained. Tubular morphologies of the products were observed by transmission electron microscope. The as-prepared magnetite nanotubes have a high aspect ratios. The magnetic properties of the nanotubes were measured by a Physical Property Measurement System. The magnetic measurements indicate that the nanotubes have superparamagnetic characteristic at room temperature, and have ferromagnetic characteristic with a coercivity of about 518 Oe at 5 K. The blocking temperature TB of the nanotubes are measured to be 95 K. The as-prepared magnetite nanotubes may find potential applications in bio-medicine.

scholarly journals Development of Gold Nanoparticles Decorated Molecularly Imprinted–Based Plasmonic Sensor for the Detection of Aflatoxin M1 in Milk Samples

Chemosensors ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 363
Author(s):  
Semra Akgönüllü ◽  
Handan Yavuz ◽  
Adil Denizli
Keyword(s):  
Low Cost ◽  
Raw Milk ◽  
Aflatoxin M1 ◽  
Template Molecule ◽  
Plasmonic Sensor ◽  
Experimental Conditions ◽  
Molecularly Imprinted ◽  
Milk Samples ◽  
Carcinogenic Substances ◽  
Allyl Mercaptan

Aflatoxins are a group of extremely toxic and carcinogenic substances generated by the mold of the genus Aspergillus that contaminate agricultural products. When dairy cows ingest aflatoxin B1 (AFB1)−contaminated feeds, it is metabolized and transformed in the liver into a carcinogenic major form of aflatoxin M1 (AFM1), which is eliminated through the milk. The detection of AFM1 in milk is very important to be able to guarantee food safety and quality. In recent years, sensors have emerged as a quick, low–cost, and reliable platform for the detection of aflatoxins. Plasmonic sensors with molecularly imprinted polymers (MIPs) can be interesting alternatives for the determination of AFM1. In this work, we designed a molecularly–imprinted–based plasmonic sensor to directly detect lower amounts of AFM1 in raw milk samples. For this purpose, we prepared gold–nanoparticle–(AuNP)−integrated polymer nanofilm on a gold plasmonic sensor chip coated with allyl mercaptan. N−methacryloyl−l−phenylalanine (MAPA) was chosen as a functional monomer. The MIP nanofilm was prepared using the light–initiated polymerization of MAPA and ethylene glycol dimethacrylate in the presence of AFM1 as a template molecule. The developed method enabled the detection of AFM1 with a detection limit of 0.4 pg/mL and demonstrated good linearity (0.0003 ng/mL–20.0 ng/mL) under optimized experimental conditions. The AFM1 determination was performed in random dairy farmer milk samples. Using the analogous mycotoxins, it was also demonstrated that the plasmonic sensor platforms were specific to the detection of AFM1.

scholarly journals Photo-Electrochemical Sensing of Dopamine by a Novel Porous TiO2 Array-Modified Screen-Printed Ti Electrode

Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3566 ◽  
Author(s):  
Francesco Tavella ◽  
Claudio Ampelli ◽  
Salvatore Leonardi ◽  
Giovanni Neri
Keyword(s):  
Modified Electrode ◽  
Limit Of Detection ◽  
Low Cost ◽  
Electrochemical Sensing ◽  
Porous Tio2 ◽  
Response Range ◽  
Potential Applications ◽  
Visible Reflectance ◽  
Screen Printed

In this paper, the development of a nanoporous TiO2 array-modified Ti electrode for photo-electrochemical (PEC) sensing of dopamine (DA) is reported. A porous TiO2 array-modified electrode was fabricated from the controlled anodic oxidation of a Ti working electrode of commercial screen-printed electrodes (SPE). The anodization process and the related morphological and microstructural transformation of the bare Ti electrode into a TiO2/Ti electrode was followed by scanning electron microscopy (SEM) and UV-visible reflectance spectroscopy (DR-UV-Vis). The modified electrode was irradiated with a low-power (120 mW) UV-Vis LED lamp (λ = 400 nm) and showed good performance for the detection of DA with a large linear response range, a sensitivity of 462 nA mM−1 cm−2, and a limit of detection of 20 µM. Moreover, it showed higher photocurrents in the presence of DA in comparison to some foreign species such as ascorbic acid, uric acid, glucose, K+, Na+, and Cl−. Thus, this proposed low-cost photo-electrochemical sensor, with the advantage of very simple fabrication, demonstrates potential applications for the determination of dopamine in real samples.

Selective Optosensing of Aminoimidazo-Azaarenes (AIAs) by CdSe/ZnS Quantum Dots-Embedded Molecularly Imprinted Silica Gel

2020 ◽  
Vol 17 ◽  
Author(s):  
Dan Qiao ◽  
Qiliang Deng ◽  
Shuo Wang
Keyword(s):  
Quantum Dots ◽  
Silica Gel ◽  
Limit Of Detection ◽  
Mutagenic Activity ◽  
Low Cost ◽  
Sol Gel ◽  
Fish Fillet ◽  
Molecularly Imprinted ◽  
Relative Standard ◽  
Molecularly Imprinted Silica

Background: The approach for the determination of aminoimidazo-azaarenes (AIAs) is urgent required due to their mutagenic activity and potential carcinogenicity. For this purpose, a CdSe/ZnS quantum dots (CdSe/ZnS QDs) - embedded molecularly imprinted silica gel with high selectivity and sensitivity was successfully prepared and applied to analyze such target. Methods: Herein, CdSe/ZnS QDs acted as the fluorescent probe, and molecularly imprinted silica gel as recognition probe was synthesized on the surface of QDs via sol-gel method. 2-Aminobenzimidazole, which has a similar structure with AIAs, as well as low cost and low toxicity, was selected as the dummy template. Results: The material has a high imprinting factor (IF=6.15); the linear range of CdSe/ZnS@MIP as a fluorescent sensing material for AIAs is 0.5-20.0 μg L -1 with the limit of detection (LOD) of 0.25 μg L -1 (3σ/s). Moreover, the fluorescent materials have been further applied to determine AIAs in beef floss and grilled fish fillet with satisfactory recoveries (82.8-110.8 %), and the relative standard deviation (RSD) is < 5.5%. Conclusion: The proposed CdSe/ZnS QDs-embedded molecularly imprinted silica gel can be used to easily and selectively detect AIAs.

scholarly journals Photocatalytic degradation of ethyl paraben wastewater by mixed crystal molecularly imprinted TiO2

2021 ◽  
Vol 261 ◽  
pp. 02025
Author(s):  
Liangxiao Zhang ◽  
Lei Zhu ◽  
Xun Wang ◽  
Xiumei Tao ◽  
Xian Liu
Keyword(s):  
Mixed Crystal ◽  
Removal Rate ◽  
Sol Gel ◽  
Tetrabutyl Titanate ◽  
Template Molecule ◽  
Molecularly Imprinted ◽  
Characterization Methods ◽  
Molecular Weights ◽  
Ph Values ◽  
Ft Ir

Using ethyl paraben as the template molecule and n-tetrabutyl titanate as the titanium source, the molecularly imprinted titanium dioxide (MIP-TiO2) photocatalyst was prepared by the sol-gel method. The effects of different pH values, imprinting molecular weights and other factors on the degradation of ethyl paraben were studied, and the materials were analyzed by TEM, XRD, FT-IR and other characterization methods. The results show that the catalyst has a mixed crystal structure in which anatase and rutile ore coexist, and the rutile ore content of MIP-TiO2 is calculated to be 78.5%. Catalytic degradation of ethyl paraben by reacting for 40 min under ultraviolet light, the removal rate of ethyl paraben by pure TiO2 is 80.74%, and the removal rate of ethyl paraben by MIP-TiO2 can reach 96.27%. MIP-TiO2 is 15.53% higher than TiO2. MIP-TiO2 has imprinting holes, which can target the target pollutants and effectively improve the selectivity of the photocatalyst MIP-TiO2. The selectivity factor of MIP-TiO2 is 1.69 times that of TiO2.

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