scholarly journals Strategy for the Development of a New Lipstick Formula

Cosmetics ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 105
Author(s):  
Luigi Rigano ◽  
Marta Montoli

The strategy to adopt for the development of a new lipstick formula requires, as a first step, the definition of the most important characteristics of a modern product. Successively, the identification of the key properties of any innovative ingredient is necessary. Then, a comprehension of the key parameters in the establishment of a stable equilibrium among the different formula components in the solid state is important. Moreover, it is necessary to study the interactions among the new ingredients and the other structural components in the formula. Finally, an evaluation of the sensory properties of the different final formulae for fine-tuning of practical performances needs to be carefully carried out. In this study, a systematic formulation approach tried to obtain a new lipstick formula using a new vegetal-derived emollient *(INCLUDING COCO-CAPRYLATE/CAPRATE, HYDROGENATED OLIVE OIL UNSAPONIFIABLES) with sensorial properties similar to some types of silicones. Some application trials of the new raw material were carried out. The following aspects of this ingredient were investigated: (1) Compatibility and thickening with waxes, (2) dispersion power of pigments, and (3) influence on sensory characteristics of the formulated lipstick. This new emollient has been shown to improve some aspects of a lipstick formula, in particular shine, homogeneity, and covering effect. The optimization of the formula, in order to increase the sensation of softness on the lips, is described. *Plantasens Olive LD SP ECO, supplier Clariant Gmbh.

Author(s):  
K. T. Tokuyasu

During the past investigations of immunoferritin localization of intracellular antigens in ultrathin frozen sections, we found that the degree of negative staining required to delineate u1trastructural details was often too dense for the recognition of ferritin particles. The quality of positive staining of ultrathin frozen sections, on the other hand, has generally been far inferior to that attainable in conventional plastic embedded sections, particularly in the definition of membranes. As we discussed before, a main cause of this difficulty seemed to be the vulnerability of frozen sections to the damaging effects of air-water surface tension at the time of drying of the sections.Indeed, we found that the quality of positive staining is greatly improved when positively stained frozen sections are protected against the effects of surface tension by embedding them in thin layers of mechanically stable materials at the time of drying (unpublished).


Author(s):  
J.L. Carrascosa ◽  
G. Abella ◽  
S. Marco ◽  
M. Muyal ◽  
J.M. Carazo

Chaperonins are a class of proteins characterized by their role as morphogenetic factors. They trantsiently interact with the structural components of certain biological aggregates (viruses, enzymes etc), promoting their correct folding, assembly and, eventually transport. The groEL factor from E. coli is a conspicuous member of the chaperonins, as it promotes the assembly and morphogenesis of bacterial oligomers and/viral structures.We have studied groEL-like factors from two different bacteria:E. coli and B.subtilis. These factors share common morphological features , showing two different views: one is 6-fold, while the other shows 7 morphological units. There is also a correlation between the presence of a dominant 6-fold view and the fact of both bacteria been grown at low temperature (32°C), while the 7-fold is the main view at higher temperatures (42°C). As the two-dimensional projections of groEL were difficult to interprete, we studied their three-dimensional reconstruction by the random conical tilt series method from negatively stained particles.


2017 ◽  
Vol 2017 (2) ◽  
pp. 41-56
Author(s):  
Thomas Alkemeyer

Two forms or rather perspectives of observations appear alongside practice theories: The first perspective can be called the „theatre perspective“: practice here is observed as a regular, spatiotemporally ordered, socially structured, and therefore recognizable historical form of „practical doings and sayings“, in which participants are understood as mere carriers of practices and their bodies as the raw material for processes of formation. In the other perspective, understood as the perspective of the participants themselves, practices come into view as ongoing, conflictual, and contingent accomplishments, in which participants occur as intelligently collaborating contributors with so called „lived bodies“. These bodies are affectable, sites of experience, and media of a sensitivity that allow an embodied self to orientate itself (with)in a practice. This paper proposes a methodological mediation of both perspectives by taking into account both a sociological analysis of discipline, formation, or adjustment, and the reflexive sensing in action, which can be modeled phenomenologically. Thus, a „lived-body-in-accomplishment“ comes into view that serves the material basis of subjectivation procceses, i. e. the (self-)formation of a constitutionally conditioned (political) agency.


Author(s):  
Juan de Lara ◽  
Esther Guerra

AbstractModelling is an essential activity in software engineering. It typically involves two meta-levels: one includes meta-models that describe modelling languages, and the other contains models built by instantiating those meta-models. Multi-level modelling generalizes this approach by allowing models to span an arbitrary number of meta-levels. A scenario that profits from multi-level modelling is the definition of language families that can be specialized (e.g., for different domains) by successive refinements at subsequent meta-levels, hence promoting language reuse. This enables an open set of variability options given by all possible specializations of the language family. However, multi-level modelling lacks the ability to express closed variability regarding the availability of language primitives or the possibility to opt between alternative primitive realizations. This limits the reuse opportunities of a language family. To improve this situation, we propose a novel combination of product lines with multi-level modelling to cover both open and closed variability. Our proposal is backed by a formal theory that guarantees correctness, enables top-down and bottom-up language variability design, and is implemented atop the MetaDepth multi-level modelling tool.


Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 766
Author(s):  
Magdalena Skotnicka ◽  
Kaja Karwowska ◽  
Filip Kłobukowski ◽  
Aleksandra Borkowska ◽  
Magdalena Pieszko

All over the world, a large proportion of the population consume insects as part of their diet. In Western countries, however, the consumption of insects is perceived as a negative phenomenon. The consumption of insects worldwide can be considered in two ways: on the one hand, as a source of protein in countries affected by hunger, while, on the other, as an alternative protein in highly-developed regions, in response to the need for implementing policies of sustainable development. This review focused on both the regulations concerning the production and marketing of insects in Europe and the characteristics of edible insects that are most likely to establish a presence on the European market. The paper indicates numerous advantages of the consumption of insects, not only as a valuable source of protein but also as a raw material rich in valuable fatty acids, vitamins, and mineral salts. Attention was paid to the functional properties of proteins derived from insects, and to the possibility for using them in the production of functional food. The study also addresses the hazards which undoubtedly contribute to the mistrust and lowered acceptance of European consumers and points to the potential gaps in the knowledge concerning the breeding conditions, raw material processing and health safety. This set of analyzed data allows us to look optimistically at the possibilities for the development of edible insect-based foods, particularly in Europe.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3297
Author(s):  
Shun-Kuo Sun ◽  
Chun-Yi Ho ◽  
Wei-Yang Yen ◽  
Su-Der Chen

Extracts from Hericium erinaceus can cause neural cells to produce nerve growth factor (NGF) and protect against neuron death. The objective of this study was to evaluate the effects of ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product on the brain cells of zebrafish embryos in both pre-dosing protection mode and post-dosing repair mode. The results showed that 1% ethanol could effectively promote zebrafish embryo brain cell death. Both 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product protected brain cells and significantly reduced the death of brain cells caused by 1% ethanol treatment in zebrafish. Moreover, the zebrafish embryos were immersed in 1% ethanol for 4 h to cause brain cell damage and were then transferred and soaked in the 200 ppm of ethanol and water extracts from H. erinaceus solid-state fermented wheat product to restore the brain cells damaged by the 1% ethanol. However, the 200 ppm extracts from the unfermented wheat medium had no protective and repairing effects. Moreover, 200 ppm of ethanol and water extracts from H. erinaceus fruiting body had less significant protective and restorative effects on the brain cells of zebrafish embryos. Both the ethanol and hot water extracts from H. erinaceus solid-state fermented wheat product could protect and repair the brain cells of zebrafish embryos damaged by 1% ethanol. Therefore, it has great potential as a raw material for neuroprotective health product.


2020 ◽  
Vol 19 (10) ◽  
pp. 1602-1618 ◽  
Author(s):  
Thibault Robin ◽  
Julien Mariethoz ◽  
Frédérique Lisacek

A key point in achieving accurate intact glycopeptide identification is the definition of the glycan composition file that is used to match experimental with theoretical masses by a glycoproteomics search engine. At present, these files are mainly built from searching the literature and/or querying data sources focused on posttranslational modifications. Most glycoproteomics search engines include a default composition file that is readily used when processing MS data. We introduce here a glycan composition visualizing and comparative tool associated with the GlyConnect database and called GlyConnect Compozitor. It offers a web interface through which the database can be queried to bring out contextual information relative to a set of glycan compositions. The tool takes advantage of compositions being related to one another through shared monosaccharide counts and outputs interactive graphs summarizing information searched in the database. These results provide a guide for selecting or deselecting compositions in a file in order to reflect the context of a study as closely as possible. They also confirm the consistency of a set of compositions based on the content of the GlyConnect database. As part of the tool collection of the Glycomics@ExPASy initiative, Compozitor is hosted at https://glyconnect.expasy.org/compozitor/ where it can be run as a web application. It is also directly accessible from the GlyConnect database.


2018 ◽  
Vol 6 (4) ◽  
pp. 401-428
Author(s):  
Miriam R. Lowi

Studies of identity and belonging in Gulf monarchies tend to privilege tribal or religious affiliation, if not the protective role of the ruler as paterfamilias. I focus instead on the ubiquitous foreigner and explore ways in which s/he contributes to the definition of national community in contemporary gcc states. Building upon and moving beyond the scholarly literature on imported labor in the Gulf, I suggest that the different ‘categories’ of foreigners impact identity and the consolidation of a community of privilege, in keeping with the national project of ruling families. Furthermore, I argue that the ‘European,’ the non-gcc Arab, and the predominantly Asian (and increasingly African) laborer play similar, but also distinct roles in the delineation of national community: while they are differentially incorporated in ways that protect the ‘nation’ and appease the citizen-subject, varying degrees of marginality reflect Gulf society’s perceptions or aspirations of the difference between itself and ‘the other(s).’


The vapour pressure theory regards osmotic pressure as the pressure required to produce equilibrium between the pure solvent and the solution. Pressure applied to a solution increases its internal vapour pressure. If the compressed solution be on one aide of a semi-permeable partition and the pure solvent on the other, there is osmotic equilibrium when the com-pression of the solution brings its vapour pressure to equality with that of the solvent. So long ago as 1894 Ramsay* found that with a partition of palladium, permeable to hydrogen but not to nitrogen, the hydrogen pressures on each side tended to equality, notwithstanding the presence of nitrogen under pressure on one side, which it might have been supposed would have resisted tin- transpiration of the hydrogen. The bearing of this experiment on the problem of osmotic pressure was recognised by van’t Hoff, who observes that "it is very instructive as regards the means by which osmotic pressure is produced." But it was not till 1908 that the vapour pressure theory of osmotic pressure was developed on a finu foundation by Calendar. He demonstrated, by the method of the "vapour sieve" piston, the proposition that “any two solutions in equilibrium through any kind of membrane or capillary surface must have the same vapour pressures in respect of each of their constituents which is capable of diffusing through their surface of separation"—a generalisation of great importance for the theory of solutions. Findlay, in his admirable monograph, gives a very complete account of the contending theories of osmotic pressure, a review of which leaves no doubt that at the present moment the vapour pressure theory stands without a serious rival Some confusion of ideas still arises from the want of adherence to a strict definition of osmotic pressure to which numerical data from experimental measurements should he reduced. Tire following definitions appear to be tire outcome of tire vapour pressure theory :— Definition I.—The vapour pressure of a solution is the pressure of the vapour with which it is in equilibrium when under pressure of its own vapour only.


1952 ◽  
Vol 2 ◽  
pp. 131-157 ◽  
Author(s):  
G. D. Ramsay

Some share—fluctuating and uncertain, but assuredly significant—of English foreign trade in modern times is to be credited to smugglers, who were ever busy in evading customs regulations and prohibitions. Mere administrative watchfulness and thoroughness could never do more than damp their activities; it was only the triumph of free trade in the early Victorian age that deprived them of their livelihood, and until then they were able to match by increase of cunning and of organization the ever more elaborate network of the customs system—its spies, its coastguards and its cutters as well as its routine officials at the ports. The smuggler flourished right down to the end of the period of protection, despite sporadic seizures by the revenue officers. In the first half of the nineteenth century, French wines, brandies and luxury textiles were being punctually shipped across the Channel in the teeth of prohibitions. In the other direction, we know, for instance, of the existence in the same period of so remarkable á phenomenon as the muslin manufacture of Tarare, near Lyons, which relied for its raw material upon the assured supply of English yarn owled abroad. But it was probably the eighteenth century, when customs regulations were at their most burdensome and complicated, that marked the classic epoch of illicit trade, the period in which the technical skill of both breakers and defenders of the law might earn the highest rewards.


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