scholarly journals Estimation of Time-Course Core Temperature and Water Loss in Realistic Adult and Child Models with Urban Micrometeorology Prediction

2019 ◽  
Vol 16 (24) ◽  
pp. 5097 ◽  
Author(s):  
Toshiki Kamiya ◽  
Ryo Onishi ◽  
Sachiko Kodera ◽  
Akimasa Hirata
Keyword(s):  
Core Temperature ◽  
Water Loss ◽  
Urban Areas ◽  
Time Course ◽  
The Body ◽  
Computational Method ◽  
Heat Index ◽  
Computational Techniques ◽  
Ambient Conditions ◽  
Urban Micrometeorology

Ambient conditions may change rapidly and notably over time in urban areas. Conventional indices, such as the heat index and wet bulb globe temperature, are useful only in stationary ambient conditions. To estimate the risks of heat-related illness, human thermophysiological responses should be followed for ambient conditions in the time domain. We develop a computational method for estimating the time course of core temperature and water loss by combining micrometeorology and human thermal response. We firstly utilize an urban micrometeorology prediction to reproduce the environment surrounding walkers. The temperature elevations and sweating in a standard adult and child are then estimated for meteorological conditions. With the integrated computational method, we estimate the body temperature and thermophysiological responses for an adult and child walking along a street with two routes (sunny and shaded) in Tokyo on 7 August 2015. The difference in the core temperature elevation in the adult between the two routes was 0.11 °C, suggesting the necessity for a micrometeorology simulation. The differences in the computed body core temperatures and water loss of the adult and child were notable, and were mainly characterized by the surface area-to-mass ratio. The computational techniques will be useful for the selection of actions to manage the risk of heat-related illness and for thermal comfort.

scholarly journals Specificity of Meteorological and Biometeorological Conditions in Central Europe in Centre of Urban Areas in June 2019 (Bydgoszcz, Poland)

Atmosphere ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 1002
Author(s):  
Monika Okoniewska
Keyword(s):  
Heat Stress ◽  
Central Europe ◽  
Water Loss ◽  
Urban Areas ◽  
High Stress ◽  
Body Water ◽  
The Body ◽  
Extreme Situation ◽  
Hot Days ◽  
Degree Of Risk

The work describes diurnal meteorological and biometeorological conditions in June 2019 in the urban areas of Central Europe. UTCI, STI, Oh_H, WL, and OV indices were calculated based on 24-h data from Bydgoszcz (Poland) for hot days. The degree of risk connected with heat stress of different intensities, risk of hyperthermia, body water loss, and decreased oxygen volume was determined. The studies showed that June 2019 was an example of an extreme situation with a heatwave that generated high stress for the inhabitants of urban areas. The conditions were burdensome mostly due to “very strong” and “strong” heat stress and periodic risk of dehydration, situations that could quickly lead to overheating of the body and a decreased oxygen volume leading to stress.

Optimal Swimming Modes of a Homo-Sapien Performing Butterfly-Stroke Kick

2006 ◽  
Author(s):  
Mark W. Pitman ◽  
Anthony D. Lucey
Keyword(s):  
Scoring Function ◽  
Optimal Solution ◽  
Displacement Function ◽  
The Body ◽  
Computational Method ◽  
Computational Techniques ◽  
Two Dimensional ◽  
Discrete Vortex ◽  
Non Linear ◽  
Butterfly Stroke

This paper outlines the development and application of a computational method that finds the most efficient two-dimensional swimming mode of a human performing fully submerged butterfly-stroke kick at high Reynolds number. The optimal solution of this non-linear problem is found using a Genetic Algorithm (GA) search method where possible solutions compete in a ‘survival of the fittest’ scheme to ‘breed’ the optimal solution. The swimming is modelled using Discrete Vortex Method (DVM) and Boundary Element Method (BEM) computational techniques. The BEM solves for the inviscid flow field around the two-dimensional body while the shedding of vorticies from joints where the curvature is high (ie. knee, waist and ankle joints) generate the vortex structures necessary for propulsion. The motion of the limbs is characterised by a displacement function which includes the possibility for simple harmonic or non-harmonic motion with a ‘rest’ period in the kick. The finite number of joints means that a finite length parameter set can be developed which characterises the motion of the swimming body. This parameter set is fed into the GA to perform the optimisation based on a scoring function. In this case, the scoring function is simply the distance that the body swims in a set amount of time. The objective of the GA is to maximise this score for a set kicking frequency. This method opens a wider possibility for optimisation of a variety of systems that involve fluid-structure interactions, particulary the possibility of optimisation in the non-linear regime of prescribed motion coupled with compliant surfaces (such as rubbery flippers) that could further increase efficiency.

Influence of stable iodine on the uptake of the thyroid – model vs. experiment

2001 ◽  
Vol 40 (01) ◽  
pp. 31-37 ◽  
Author(s):  
U. Wellner ◽  
E. Voth ◽  
H. Schicha ◽  
K. Weber
Keyword(s):  
Time Course ◽  
Compartment Model ◽  
The Body ◽  
Iodine Uptake ◽  
Model Calculations ◽  
Physiological Conditions ◽  
Iodine Supply ◽  
Predicted Values ◽  
The Individual ◽  
Stable Iodine

Summary Aim: The influence of physiological and pharmacological amounts of iodine on the uptake of radioiodine in the thyroid was examined in a 4-compartment model. This model allows equations to be derived describing the distribution of tracer iodine as a function of time. The aim of the study was to compare the predictions of the model with experimental data. Methods: Five euthyroid persons received stable iodine (200 μg, 10 mg). 1-123-uptake into the thyroid was measured with the Nal (Tl)-detector of a body counter under physiological conditions and after application of each dose of additional iodine. Actual measurements and predicted values were compared, taking into account the individual iodine supply as estimated from the thyroid uptake under physiological conditions and data from the literature. Results: Thyroid iodine uptake decreased from 80% under physiological conditions to 50% in individuals with very low iodine supply (15 μg/d) (n = 2). The uptake calculated from the model was 36%. Iodine uptake into the thyroid did not decrease in individuals with typical iodine supply, i.e. for Cologne 65-85 μg/d (n = 3). After application of 10 mg of stable iodine, uptake into the thyroid decreased in all individuals to about 5%, in accordance with the model calculations. Conclusion: Comparison of theoretical predictions with the measured values demonstrated that the model tested is well suited for describing the time course of iodine distribution and uptake within the body. It can now be used to study aspects of iodine metabolism relevant to the pharmacological administration of iodine which cannot be investigated experimentally in humans for ethical and technical reasons.

scholarly journals Transition from Emotional to Rational Advertising for Food Products on the Romanian Market

2017 ◽  
Vol 50 (1) ◽  
pp. 101-108
Author(s):  
A.F. Jităreanu ◽  
Elena Leonte ◽  
A. Chiran ◽  
Benedicta Drobotă
Keyword(s):  
Urban Areas ◽  
Eating Habits ◽  
Well Being ◽  
Point Of View ◽  
The Body ◽  
Positive Effects ◽  
New Methods ◽  
Brand Advertising ◽  
Tangible Evidence ◽  
Health And Well Being

Abstract Advertising helps to establish a set of assumptions that the consumer will bring to all other aspects of their engagement with a given brand. Advertising provides tangible evidence of the financial credibility and competitive presence of an organization. Persuasion is becoming more important in advertising. In marketing, persuasive advertising acts to establish wants/motivations and beliefs/attitudes by helping to formulate a conception of the brand as being one which people like those in the target audience would or should prefer. Considering the changes in lifestyle and eating habits of a significant part of the population in urban areas in Romania, the paper aims to analyse how brands manage to differentiate themselves from competitors, to reposition themselves on the market and influence consumers, meeting their increasingly varied needs. Food brands on the Romanian market are trying, lately, to identify new methods of differentiation and new benefits for their buyers. Given that more and more consumers are becoming increasingly concerned about what they eat and the products’ health effects, brands struggle to highlight the fact that their products offer real benefits for the body. The advertisements have become more diversified and underline the positive effects, from the health and well - being point of view, that those foods offer (no additives and preservatives, use of natural ingredients, various vitamins and minerals or the fact that they are dietary). Advertising messages’ diversification is obvious on the Romanian market, in the context of an increasing concern of the population for the growing level of information of some major consumer segments.

scholarly journals Involvement of Autophagy in Rat Tail Static Compression-Induced Intervertebral Disc Degeneration and Notochordal Cell Disappearance

2021 ◽  
Vol 22 (11) ◽  
pp. 5648
Author(s):  
Takashi Yurube ◽  
Hiroaki Hirata ◽  
Masaaki Ito ◽  
Yoshiki Terashima ◽  
Yuji Kakiuchi ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Time Course ◽  
The Body ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Autophagic Flux ◽  
Static Compression ◽  
Notochordal Cell ◽  
Notochordal Cells ◽  
Rat Tail

The intervertebral disc is the largest avascular low-nutrient organ in the body. Thus, resident cells may utilize autophagy, a stress-response survival mechanism, by self-digesting and recycling damaged components. Our objective was to elucidate the involvement of autophagy in rat experimental disc degeneration. In vitro, the comparison between human and rat disc nucleus pulposus (NP) and annulus fibrosus (AF) cells found increased autophagic flux under serum deprivation rather in humans than in rats and in NP cells than in AF cells of rats (n = 6). In vivo, time-course Western blotting showed more distinct basal autophagy in rat tail disc NP tissues than in AF tissues; however, both decreased under sustained static compression (n = 24). Then, immunohistochemistry displayed abundant autophagy-related protein expression in large vacuolated disc NP notochordal cells of sham rats. Under temporary static compression (n = 18), multi-color immunofluorescence further identified rapidly decreased brachyury-positive notochordal cells with robust expression of autophagic microtubule-associated protein 1 light chain 3 (LC3) and transiently increased brachyury-negative non-notochordal cells with weaker LC3 expression. Notably, terminal deoxynucleotidyl transferase dUTP nick end labeling-positive apoptotic death was predominant in brachyury-negative non-notochordal cells. Based on the observed notochordal cell autophagy impairment and non-notochordal cell apoptosis induction under unphysiological mechanical loading, further investigation is warranted to clarify possible autophagy-induced protection against notochordal cell disappearance, the earliest sign of disc degeneration, through limiting apoptosis.

scholarly journals Occupant behaviour and thermal comfort in buildings: Monitoring the end user

2019 ◽  
Vol 111 ◽  
pp. 04056
Author(s):  
Loes Visser ◽  
Boris Kingma ◽  
Eric Willems ◽  
Wendy Broers ◽  
Marcel Loomans ◽  
...  
Keyword(s):  
Thermal Comfort ◽  
Energy Performance ◽  
The Body ◽  
Activity Level ◽  
Biophysical Model ◽  
Zone Model ◽  
Occupant Behaviour ◽  
Ambient Conditions ◽  
Skin Temperatures ◽  
Thermoregulatory Behaviour

Studies indicate that the energy performance gap between real and calculated energy use can be explained for 80% by occupant behaviour. This human factor may be composed of routine and thermoregulatory behaviour. When occupants do not feel comfortable due to high or low operative temperatures and resulting high or low skin temperatures, they are likely to exhibit thermoregulatory behaviour. The aim of this study is to monitor and understand this thermoregulatory behaviour of the occupant. This is a detailed study of two females living in a rowhouse in the city of Heerlen (Netherlands). During a monitoring period of three weeks over a time span of three months the following parameters were monitored: activity level, clothing, micro climate, skin temperatures and thermal comfort and sensation. Their micro climate was measured at five positions on the body to assess exposed near body conditions and skin temperature. Every two hours they filled in a questionnaire regarding their thermal comfort and sensation level (7-point scale), clothing, activities and thermoregulatory behaviour. The most comfortable (optimal) temperature was calculated for each person by adopting a biophysical model, a thermoneutral zone model. This study shows unique indivual comfort patterns in relation to ambient conditions. An example is given how this information can be used to calculate the buildings energy comsumption.

Modeling the Mechanics of Tethers Pulled From the Cochlear Outer Hair Cell Membrane

2008 ◽  
Vol 130 (3) ◽  
Author(s):  
Kristopher R. Schumacher ◽  
Aleksander S. Popel ◽  
Bahman Anvari ◽  
William E. Brownell ◽  
Alexander A. Spector
Keyword(s):  
Cell Membrane ◽  
Hair Cell ◽  
Outer Hair Cell ◽  
Lateral Wall ◽  
Outer Hair Cells ◽  
The Body ◽  
Computational Method ◽  
Membrane Properties ◽  
Bending Modulus ◽  
Sound Amplification

Cell membrane tethers are formed naturally (e.g., in leukocyte rolling) and experimentally to probe membrane properties. In cochlear outer hair cells, the plasma membrane is part of the trilayer lateral wall, where the membrane is attached to the cytoskeleton by a system of radial pillars. The mechanics of these cells is important to the sound amplification and frequency selectivity of the ear. We present a modeling study to simulate the membrane deflection, bending, and interaction with the cytoskeleton in the outer hair cell tether pulling experiment. In our analysis, three regions of the membrane are considered: the body of a cylindrical tether, the area where the membrane is attached and interacts with the cytoskeleton, and the transition region between the two. By using a computational method, we found the shape of the membrane in all three regions over a range of tether lengths and forces observed in experiments. We also analyze the effects of biophysical properties of the membrane, including the bending modulus and the forces of the membrane adhesion to the cytoskeleton. The model’s results provide a better understanding of the mechanics of tethers pulled from cell membranes.

Tuning of a Basic Coordination Pattern Constructs Straight-Ahead and Curved Walking in Humans

2004 ◽  
Vol 91 (4) ◽  
pp. 1524-1535 ◽  
Author(s):  
Grégoire Courtine ◽  
Marco Schieppati
Keyword(s):  
Principal Components ◽  
Lower Limb ◽  
Time Course ◽  
Body Movement ◽  
The Body ◽  
Whole Body ◽  
Coordination Pattern ◽  
Data Set ◽  
Coordination Patterns ◽  
Straight Ahead

We tested the hypothesis that common principles govern the production of the locomotor patterns for both straight-ahead and curved walking. Whole body movement recordings showed that continuous curved walking implies substantial, limb-specific changes in numerous gait descriptors. Principal component analysis (PCA) was used to uncover the spatiotemporal structure of coordination among lower limb segments. PCA revealed that the same kinematic law accounted for the coordination among lower limb segments during both straight-ahead and curved walking, in both the frontal and sagittal planes: turn-related changes in the complex behavior of the inner and outer limbs were captured in limb-specific adaptive tuning of coordination patterns. PCA was also performed on a data set including all elevation angles of limb segments and trunk, thus encompassing 13 degrees of freedom. The results showed that both straight-ahead and curved walking were low dimensional, given that 3 principal components accounted for more than 90% of data variance. Furthermore, the time course of the principal components was unchanged by curved walking, thereby indicating invariant coordination patterns among all body segments during straight-ahead and curved walking. Nevertheless, limb- and turn-dependent tuning of the coordination patterns encoded the adaptations of the limb kinematics to the actual direction of the walking body. Absence of vision had no significant effect on the intersegmental coordination during either straight-ahead or curved walking. Our findings indicate that kinematic laws, probably emerging from the interaction of spinal neural networks and mechanical oscillators, subserve the production of both straight-ahead and curved walking. During locomotion, the descending command tunes basic spinal networks so as to produce the changes in amplitude and phase relationships of the spinal output, sufficient to achieve the body turn.

Spiracular Structure and Water Loss from Tribolium confusum Jacq. and Sitophilus granarius (L.) under Reduced Pressures

1963 ◽  
Vol 95 (4) ◽  
pp. 352-357 ◽  
Author(s):  
J. Sharplin ◽  
H. J. Bhambhani
Keyword(s):  
Water Loss ◽  
Tribolium Confusum ◽  
The Body ◽  
Sitophilus Granarius ◽  
Reduced Pressure ◽  
Low Pressures ◽  
Anomalous Water ◽  
Reduced Pressures

AbstractThe structure and position of the spiracles in Sitophilus granarius and Tribolium confusum adults was studied. On the basis of this an attempt was made to explain the differences in water loss from these two species under reduced pressure. It was concluded that the spiracular structure combined with the inflation of the body under very low pressures, can account for the apparently anomalous water loss results.

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