scholarly journals Transitions in the Careers of Competitive Swimmers: To Continue or Finish with Elite Sport?

2020 ◽  
Vol 17 (18) ◽  
pp. 6482 ◽  
Author(s):  
Malgorzata Siekanska ◽  
Jan Blecharz
Keyword(s):  
Personal Growth ◽  
Developmental Stages ◽  
Structured Interview ◽  
Practical Applications ◽  
Group I ◽  
Elite Level ◽  
Group Ii ◽  
Career Termination ◽  
Competitive Swimmers ◽  
Athletic Career

An athletic career is a succession of stages and transitions (normative and non-normative), which may have decisive effects on either maintaining a satisfactory and/or successful course or deciding about premature career termination. The main purpose of this study was to identify differences between swimmers (Mage = 21.32, SD = 2.62) who after undergoing the transition from junior to senior level either: (a) continued their career hoping to improve their performance regardless of low success at the elite level—Group I; or (b) decided on premature athletic career termination—Group II. The criteria for inclusion included having undergone the transition from junior to senior level and having competed at elite level for at least a year (M = 4.14 years, SD = 1.74). The participants were administered a demographic survey and a structured interview. The results revealed differences in developmental stages. The exploration phase was longer (MGroup I = 5.8 yrs, SD = 2.04, MGroup II = 4.6 yrs, SD = 2.4; Z = −1.902, p = 0.057); the commitment phase was shorter (MGroup I = 3.6 yrs, SD = 1.3; MGroup II = 4.6 yrs, SD = 1.7; Z = −1.735, p = 0.083); the number of hours of structured practice were (MGroup I = 5975, SD = 2474; MGroup II = 7623, SD = 2660, Z = −1.928, p = 0.054); the number of perceived costs were (Group I = 22, Group II = 34; Z = −2.209, p = 0.0027); and the most often pointed benefits of a sporting career were (Group I—94% health & physical fitness; Group II—88% personal growth & life skills). Furthermore, essential inhibitors and facilitators of athletes’ development were identified. The findings of the study have practical applications for athletes, coaches, parents and sport psychology professionals. For instance, appropriate social support can help to prevent elite athletes’ premature career termination from professional sport during and after their normative transition from junior to senior level.

scholarly journals A comparative genetical study on DDT resistance in adults and larvae of the mosquito Aedes aegypti L

1967 ◽  
Vol 10 (3) ◽  
pp. 219-228 ◽  
Author(s):  
R. J. Wood
Keyword(s):  
Linkage Group ◽  
Developmental Stages ◽  
Major Gene ◽  
Group Iii ◽  
Group I ◽  
Fourth Larval Stage ◽  
Ddt Resistance ◽  
Group Ii ◽  
The Difference ◽  
Two Stages

Inheritance of DDT resistance has been studied in crosses between the highly resistant ‘T’ strain of A. aegypti (constituted by inbreeding from the TRINIDAD DDT-resistant stock) and the ‘64’ susceptible strain.Larval DDT resistance derives from a major gene RDDT1 on linkage group II, the order being RDDT1–s–y. Linkage group III may also contribute to larval resistance. Linkage group I makes no contribution.Adult DDT resistance derives from a major gene RDDT2, 18·2 ± 2·1 units from the market blt on linkage group III. Linkage group II has no influence on adult resistance.Selection with DDT to retain only RDDT1/+ segregants in larvae of backcrosses RDDT1/+×+/+ did not increase resistance in resulting adults, confirming the difference in genetic mechanism at the two stages.The F1 progenies from reciprocal crosses between ‘T’ and ‘64’ differed slightly but significantly in larval resistance, modifying the influence of the major gene RDDT1 in the heterozygote.The early developmental stages of the RDDT1/+ phenotype (up to the fourth larval stage) were more viable than the +/+ phenotype in backcross segregation. The difference in mortality probably exceeded 30%.

scholarly journals Grupo de orientação multiprofissional para pacientes transplantados renais e familiares

2021 ◽  
Vol 11 (34) ◽  
pp. 296-306
Author(s):  
Beatriz Pinheiro da Mota Costa ◽  
Alessandra Rosa Vicari ◽  
Carla Elisabete da Silva Oliveira ◽  
Fernanda Guarilha Boni ◽  
Isabel Cristina Echer
Keyword(s):  
Kidney Transplantation ◽  
Kidney Transplant ◽  
Personal Growth ◽  
Family Members ◽  
Structured Interview ◽  
University Hospital ◽  
Transplant Patients ◽  
Group I ◽  
Kidney Transplant Patients ◽  
The Impact

Conhecer a percepção de pacientes e familiares acerca do grupo de orientação multiprofissional para transplantados renais. Método: trata-se de um estudo qualitativo realizado em hospital universitário do sul do Brasil nos meses de fevereiro a maio do ano de 2019. As informações foram coletadas pelos pesquisadores por meio de entrevista estruturada com os participantes do grupo de orientação multiprofissional. Foi realizada a técnica de análise de conteúdo. Resultados: participaram 15 pacientes transplantados renais e quatro familiares. A análise dos depoimentos resultou em três categorias: “Motivação para participar do grupo”, “Sou transplantado renal, e agora?” e “Compreendendo as orientações: o impacto no autocuidado”. As orientações em grupo foram consideradas objetivas, claras e relevantes para a recuperação. Considerações finais: participar do grupo possibilitou estreitamento de laços familiares/profissionais, crescimento pessoal, maior conhecimento sobre o transplante renal, mudança de comportamento e comprometimento com o autocuidado.Descritores: Enfermagem, Transplante de Rim, Equipe de Assistência ao Paciente, Educação em Saúde. Multiprofessional guidance group for kidney and family transplant patientsAbstract: To know the perception of patients and family members about the multiprofessional guidance group for kidney transplant patients. Method: this is a qualitative study carried out at a university hospital in southern Brazil from February to May of 2019. The information was collected by the researchers through a structured interview with the participants of the multiprofessional guidance group. The content analysis technique was performed. Results: 15 kidney transplant patients and four family members participated. The analysis of the testimonies resulted in three categories: “Motivation to participate in the group”, “I am a kidney transplanted, what now?” and “Understanding the guidelines: the impact on self-care”. The group guidelines were considered objective, clear and relevant to recovery. Final considerations: to participate in the group allowed for closer family/professional ties, personal growth, greater knowledge about kidney transplantation, behavior change and commitment to self-care.Descriptors: Nursing, Kidney Transplantation, Patient Care Team, Health Education. Grupo de orientación multiprofesional para pacientes con trasplante renal y familiarResumen: Conocer la percepción de los pacientes y familiares sobre el grupo de orientación multiprofesional para pacientes con trasplante renal. Método: es un estudio cualitativo realizado en un hospital universitario del sur de Brasil de febrero a mayo de 2019. La información fue recolectada por los investigadores mediante una entrevista estructurada con los participantes del grupo de orientación multiprofesional. Se realizó la técnica de análisis de contenido. Resultados: participaron 15 pacientes con trasplante renal y cuatro familiares. El análisis de los testimonios resultó en tres categorías: “Motivación para participar en el grupo”, “Soy un trasplante de riñón, ¿ahora qué?” y “Comprender las pautas: el impacto en el autocuidado”. Las pautas del grupo se consideraron objetivas, claras y relevantes para la recuperación. Consideraciones finales: participar en el grupo permitió estrechar lazos familiares/profesionales, crecimiento personal, mayor conocimiento sobre trasplante de riñón, cambio de comportamiento y compromiso con el autocuidado.Descriptores: Enfermería, Trasplante de Riñón, Grupo de Atención al Paciente, Educación en Salud.

scholarly journals Co-morbidities of Nocturia among Adults: A Cross-sectional Study in Southern India

2020 ◽  
Author(s):  
Susamma Varughese ◽  
TP Rajeev ◽  
Devina E Rodrigues
Keyword(s):  
Structured Interview ◽  
Precipitating Factors ◽  
Cross Sectional ◽  
Time Frequency ◽  
Spicy Food ◽  
Group I ◽  
Increased Risk ◽  
Co Morbidity ◽  
Significant Difference ◽  
Group Ii

Introduction: Night urination severely impacts the quality of life among adults. Coexisting factors such as age, obesity, diabetes, hypertension, cardiac diseases, UTI, asthma, anxiety, and depression are significantly related when voiding episodes exceed two per night. However, understanding its associated factors are essential aspects in the management of Nocturia. Aim: The aim of the study was to determine the association of nocturia with selected demographic variables, co-morbidities, and the precipitating factors among adults with voiding episodes two or more times and adults who void only once at night. Materials and Methods: A descriptive cross-sectional design was carried out among 420 adults of age 35-65 years with voiding over two times (Group I) and 206 adults of age 35-65 years who voided only once (Group II) a night. The data was collected from two selected hospitals of Mangalore between January 2018 and June 2019. The written permission was taken from the concerned authority, after obtaining the informed consent from the subjects. The baseline proforma was assessed by the researcher using structured interview schedule and the questionnaire on co-morbidity and precipitating factors such as regular intake of alcoholism, smoking, consumption of coffee, spicy food, anxiety, urinate before bedtime, use of diuretics, day time frequency, underwent surgeries was filled by the subjects. The data was analysed using frequency, percentage, Chi-square test, and logistic regression statistics by Statistical Package for the Social Sciences (SPSS) Version 16. Results: The study observed that the risk of nocturia was significantly higher among Group I subjects with Urinary Tract Infection (UTI), constipation, hypertension, and on medication for various diseases compared with Group II. The precipitating factors of nocturia revealed that Group I subjects who regularly took coffee, spicy food, had anxiety, daytime frequency, and had undergone various surgeries showed significant difference associated with increased risk of nocturia compared with Group II. Conclusion: The study findings demonstrate that nocturia is strongly associated with multiple co-morbidities and precipitating factors. These results therefore provide evidence to establish the primary and secondary preventive strategies among adults with nocturia.

Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

1970 ◽  
Vol 28 ◽  
pp. 208-209
Author(s):  
K.K. SEKHRI ◽  
C.S. ALEXANDER ◽  
H.T. NAGASAWA
Keyword(s):  
Osmium Tetroxide ◽  
Male Mice ◽  
Alcohol Group ◽  
Group Iii ◽  
Group I ◽  
C57bl Mice ◽  
Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

Heterogeneity and Immunochemical Properties of Anti-β2-glycoprotein I Autoantibodies

1998 ◽  
Vol 80 (09) ◽  
pp. 393-398 ◽  
Author(s):  
V. Regnault ◽  
E. Hachulla ◽  
L. Darnige ◽  
B. Roussel ◽  
J. C. Bensa ◽  
...  
Keyword(s):  
Fluid Phase ◽  
Anticardiolipin Antibodies ◽  
Dual Reactivity ◽  
Group Iii ◽  
Important Group ◽  
Epitope Specificity ◽  
Glycoprotein I ◽  
Group I ◽  
Group Ii ◽  
Sufficient Concentration

SummaryMost anticardiolipin antibodies (ACA) associated with antiphospholipid syndrome (APS) are directed against epitopes expressed on β2-glycoprotein I (β2GPI). Despite a good correlation between standard ACA assays and those using purified human β2GPI as the sole antigen, some sera from APS patients only react in the latter. This is indicative of heterogeneity in anti-β2GPI antibodies. To characterize their reactivity profiles, human and bovine β2GPI were immobilized on γ-irradiated plates (β2GPI-ELISA), plain polystyrene precoated with increasing cardiolipin concentrations (CL/β2GPI-ELISA), and affinity columns. Fluid-phase inhibition experiments were also carried out with both proteins. Of 56 selected sera, restricted recognition of bovine or human β2GPI occurred respectively in 10/29 IgA-positive and 9/22 IgM-positive samples, and most of the latter (8/9) were missed by the standard ACA assay, as expected from a previous study. Based on species specificity and ACA results, IgG-positive samples (53/56) were categorized into three groups: antibodies reactive to bovine β2GPI only (group I) or to bovine and human β2GPI, group II being ACA-negative, and group III being ACA-positive. The most important group, group III (n = 33) was characterized by (i) binding when β2GPI was immobilized on γ-irradiated polystyrene or cardiolipin at sufficient concentration (regardless of β2GPI density, as assessed using 125I-β2GPI); (ii) and low avidity binding to fluid-phase β2GPI (Kd in the range 10–5 M). In contrast, all six group II samples showed (i) ability to bind human and bovine β2GPI immobilized on non-irradiated plates; (ii) concentration-dependent blockade of binding by cardiolipin, suggesting epitope location in the vicinity of the phospholipid binding site on native β2GPI; (iii) and relative avidities approximately 100-fold higher than in group III. Group I patients were heterogeneous with respect to CL/β2GPI-ELISA and ACA results (6/14 scored negative), possibly reflecting antibody differences in terms of avidity and epitope specificity. Affinity fractionation of 23 sera showed the existence, in individual patients, of various combinations of antibody subsets solely reactive to human or bovine β2GPI, together with cross-species reactive subsets present in all samples with dual reactivity namely groups III and II, although the latter antibodies were poorly purified on either column. Therefore, the mode of presentation of β2GPI greatly influences its recognition by anti-β2GPI antibodies with marked inter-individual heterogeneity, in relation to ACA quantitation and, possibly, disease presentation and pathogenesis.

Treatment of venous leg ulcers with sulodexide

Phlebologie ◽  
2003 ◽  
Vol 32 (05) ◽  
pp. 115-120 ◽  
Author(s):  
A. Franek ◽  
H. Koziolek ◽  
M. Kucharzewski
Keyword(s):  
Pharmacological Treatment ◽  
Healing Process ◽  
Leg Ulcers ◽  
Venous Ulceration ◽  
Venous Leg Ulcers ◽  
Group I ◽  
Group Ii

SummaryAim: The study of the influence of sulodexide in the treatment of venous leg ulcers. Patients and method: 44 patients with chronic venous ulceration were randomly divided into two groups. Group I: 21 patients (ulceration area: 12.7-18.9 cm2), Group II: 23 patients (ulceration size: 12.1-20.3 cm2). Both groups were treated by using Unna’s boot. This dressing was changed every seven days until the ulcer had healed. Additionally, the patients in group II received the systemic pharmacological treatment with sulodexide. Results: After 7 weeks of treatment ulcers of seven patients (35%) from group I had healed, and 3 weeks later the ulceration of two more patients had healed completely. After further 7 weeks the ulcers of 12 patients had healed completely. Whereas in group II after 7 weeks of treatment ulceration of 16 (70%, p <0.05) patient had healed completely and after further 3 weeks the ulcers of the remaining 7 patients had healed, too. Conclusion: The use of sulodexide in patients with chronic venous leg ulcers accelerates the healing process.

Effects of Rest and Exercise on Cardiac Blood Volume Determinations

1997 ◽  
Vol 36 (08) ◽  
pp. 259-264
Author(s):  
N. Topuzović
Keyword(s):  
Radionuclide Ventriculography ◽  
Left Ventricular ◽  
Peak Exercise ◽  
Volume Determination ◽  
Group I ◽  
Lv Volumes ◽  
Group Ii ◽  
Lv Volume

Summary Aim: The purpose of this study was to investigate the changes in blood activity during rest, exercise and recovery, and to assess its influence on left ventricular (LV) volume determination using the count-based method requiring blood sampling. Methods: Forty-four patients underwent rest-stress radionuclide ventriculography; Tc-99m-human serum albumin was used in 13 patients (Group I), red blood cells was labeled using Tc-99m in 17 patients (Group II) in vivo, and in 14 patients (Group III) by modified in vivo/in vitro method. LV volumes were determined by a count-based method using corrected count rate in blood samples obtained during rest, peak exercise and after recovery. Results: In group I at stress, the blood activity decreased by 12.6 ± 5.4%, p <0.05, as compared to the rest level, and increased by 25.1 ± 6.4%, p <0.001, and 12.8 ± 4.5%, p <0.05, above the resting level in group II and III, respectively. This had profound effects on LV volume determinations if only one rest blood aliquot was used: during exercise, the LV volumes significantly decreased by 22.1 ± 9.6%, p <0.05, in group I, whereas in groups II and III it was significantly overestimated by 32.1 ± 10.3%, p <0.001, and 10.7 ± 6.4%, p <0.05, respectively. The changes in blood activity between stress and recovery were not significantly different for any of the groups. Conclusion: The use of only a single blood sample as volume aliquot at rest in rest-stress studies leads to erroneous estimation of cardiac volumes due to significant changes in blood radioactivity during exercise and recovery.

A P-Selectin/CD62P Monoclonal Antibody (LYP-20), in Tandem with Flow Cytometry, Detects in vivo Activated Circulating Rat Platelets in Severe Vascular Trauma

1994 ◽  
Vol 72 (05) ◽  
pp. 745-749 ◽  
Author(s):  
Elza Chignier ◽  
Maud Parise ◽  
Lilian McGregor ◽  
Caroline Delabre ◽  
Sylvie Faucompret ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Flow Cytometry ◽  
Platelet Activation ◽  
Peripheral Blood ◽  
Vascular Trauma ◽  
Activated Platelets ◽  
Group I ◽  
Group Ii ◽  
Rat Platelets

SummaryP-selectin, also known as CD62P, GMP140 or PADGEM, is present in platelet a-granules and endothelial cell Weibel-Palade bodies and is very rapidly expressed on the surface of these cells on activation. In this study, an anti P-selectin monoclonal antibody (LYP20) was used, in tandem with flow cytometry, to identify activated platelets at the site of induced vascular trauma or in peripheral blood. Moreover, electron microscopy was performed to characterize sites of vascular trauma and quantify the number of adhering platelets. The same induced vascular trauma was observed to result into animals responding in 2 different ways (Group I, Group II) following the degree of platelet activation. Five rats, out of 14 with induced vascular trauma, had more than half of their circulating platelets expressing P-selectin when drawn at the site of the trauma (67.4% ± 3.44) or in peripheral blood (78.5% ± 2.5) (Group I). In the remaining 9 animals a much smaller proportion of circulating platelets expressed P-selectin when assayed from trauma sites (18% ± 3.34) or in peripheral blood (18.0% ± 4.30) (Group II). Enhanced P-selectin expression by circulating platelets in Group I, compared to Group II, appears to be linked to the degree of activated platelets adhering at sites of trauma (171 ± 15 × 103 platelets versus 48 ± 31 × 103 platelets per mm2). In the 5 control animals, that were not operated on, platelets expressing P-selectin when drawn at the site of a mock trauma (7.0% ± 1.84) or in the peripheral blood (11.2% ± 3.30) showed little activation. In addition, no platelet adhesion was seen on the vascular bed of these animals. Results from this study show that analysis of P-selectin (CD62P) expression, in circulating platelets, is a valuable and rapid marker of platelet activation following severe vascular trauma induced in rats. However, activated platelets were not detected to the same extent in the peripheral blood of all animals having undergone vascular trauma. It is conceivable that platelets, depending on the degree of activation, may be actively sequestered in organs and prevented from circulating. Alternatively, P-selectin may be rapidly endocytosed, or not expressed, by activated circulating platelets depending on the type of agonists implicated in vivo activation.

Assessment of Acute Kidney Injury in Patients Undergoing Elective Coronary Angiography and Percutaneous Coronary Intervention

2012 ◽  
Vol 5 (1) ◽  
pp. 37-43
Author(s):  
ABMM Alam ◽  
M Moniruzzaman ◽  
MB Alam ◽  
N Islam ◽  
F Khatoon ◽  
...  
Keyword(s):  
Serum Creatinine ◽  
Contrast Media ◽  
Creatinine Level ◽  
Ace Inhibitor ◽  
Kidney Injury ◽  
Coronary Intervention ◽  
Group I ◽  
Percutaneous Coronary ◽  
The Mean ◽  
Group Ii

Background: CIN has gained increased attention in the clinical setting, particularly during cardiac intervention but also in many other radiological procedures in which iodinated contrast media are used. There is at present good clinical evidence from well-controlled randomized studies that CIN is a common cause of acute renal dysfunction.Methodology: This was a prospective study conducted among the patients who underwent coronary angiography and percutaneous coronary intervention in the Department of Cardiology, Dhaka Medical College Hospital during January 2010 to December 2010. A total of 111 patients age range from 25 to 75 years were included in the study. Serum creatinine level at baseline and at the end of 48 hours was done in all these patients. Study population was divided into two groups according to development of acute kidney injury (AKI). Group-I = AKI, Group II = Not developed AKI. Results: AKI developed 11.7% of the study patient. DM and Preexisting renal insufficiency were significantly higher in group I patients. HTN was (61.5% Vs 44.9%) higher in group I but not significantly. History of ACE inhibitor/ARB, NSAID intake and LVEF <40% were significantly higher in group I patients. The mean±SD volume of CM (Contrast Media) were 156.9±44.8 ml and 115.4±30.0 ml in group I and group II respectively, which was significant. The mean±SD of serum creatinine after 48-72 hours of CAG/PCI was 1.4±0.37 mg/dl and 1.1±0.2 mg/dl in group I and group II respectively. The serum creatinine level increased significantly (p<0.05) after 48-72 hours of CAG/PCI in group I. In group II, S. creatinine level increased but not significant (p>0.05). Impaired renal function was found 76.9% and 2.0% in group I and group II respectively. DM, HTN, preexisting renal insufficiency, ACE inhibitor/ARB, NSAIDs, contrast volume (>150 ml), eGFR (<60 ml/min/ 1.73m2) and LVEF (<40%) are significantly (p0.05) associated for CIN development.Conclusion: CIN is an iatrogenic but preventable disorder results from the administration of contract media. Although rare in the general population, CIN occurs frequently in patients with underlying renal dysfunction and diabetes. In patients with pre angiographic normal renal function, the prevalence is low but in pre-existing renal impairment it may pose a serious threat. Thus risk factors are synergistic in their ability to predispose to the development of CIN. A careful risk-benefit analysis must always be performed prior to the administration of contrast media to patients at risk for CIN. DOI: http://dx.doi.org/10.3329/cardio.v5i1.12227 Cardiovasc. j. 2012; 5(1): 37-43

Effect of prolactin inhibition under heat exposure on water intake and excretion of urine, sodium and potassium in bulls

1980 ◽  
Vol 94 (3) ◽  
pp. 315-320 ◽  
Author(s):  
D. Schams ◽  
E. Stephan ◽  
R. D. Hooley
Keyword(s):  
Water Intake ◽  
Heat Exposure ◽  
Physiological Role ◽  
Treated Group ◽  
Serum Prolactin ◽  
Control Value ◽  
Light Regimen ◽  
Group I ◽  
Urinary Potassium ◽  
Group Ii

Abstract. Six Holstein bulls were housed in a climate-chamber under constant light regimen and after two weeks of preconditioning at 15°C, 60% relative humidity RH (day) and 12°C, 60% RH (night) were subjected to two weeks of heat exposure. This involved one week at 30°C and 60% RH (day) and 25°C and 60% RH (night) and a further week at 35°C, 60% RH (day) and 30°C, 60% RH (night). Three bulls were untreated (group I) and 3 bulls were treated (group II) just before and during heat exposure with a prolactin inhibitor to study the possible physiological role of prolactin on the regulation of water, potassium and sodium. Serum prolactin levels increased significantly (P < 0.01) in group I from the control value of 6 ng/ml to 33 and 44 ng/ml when the ambient temperature was increased (weeks 3 and 4) and then decreased to 21 and 12 ng/ml after reduction in temperature during weeks 5 and 6, respectively. For group II prolactin values decreased under the treatment with the prolactin inhibitor to 0.5 ng/ml and remained at this level throughout the experiment. GH levels were unaffected by heat treatment or by treatment with prolactin inhibitor. There were no differences between groups I and II in respiratory rate, pulse rate and rectal temperature. Water intake increased in both groups under heat exposure but decreased significantly afterwards only in group II. Differences in urinary excretion volume and blood serum osmolality were not significant. Urinary potassium and sodium excretion were unchanged in group II but increased with heat exposure in group I. During heat exposure 2 bulls of group II lost weight despite maintaining food intake.

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