scholarly journals Boosting Psychological Well-Being through a Social Mindfulness-Based Intervention in the General Population

2020 ◽  
Vol 17 (22) ◽  
pp. 8404
Author(s):  
Teresa Fazia ◽  
Francesco Bubbico ◽  
Gerardo Salvato ◽  
Giovanni Berzuini ◽  
Salvatore Bruno ◽  
...  
Keyword(s):  
Experimental Design ◽  
General Population ◽  
Psychological Functioning ◽  
Intervention Program ◽  
Passive Control ◽  
Preventive Measure ◽  
Well Being ◽  
Linear Mixed Effect Model ◽  
Social Aspect ◽  
Mixed Effect

The benefits of mindfulness meditation among clinical and non-clinical populations have been largely reported in literature. Existing mindfulness-based programs are particularly useful in targeting specific populations while researchers have pointed out the possibility of developing programs adapted to the audience and the context. In this two-groups pre-post experimental design we developed a mindfulness-based social intervention program to target individuals from the general population. Here we present a two-groups pre-post experimental design to investigate its effectiveness on participants’ psychological functioning assessed by eight self-reported questionnaires (CORE-OM, FFMQ, SWLS, PANAS, PSS, SCS, WEMWBS, SHS) which encompass different domains of well-being, mindfulness and emotional functioning. Participants, recruited on voluntary basis, were randomly allocated to treated or passive control groups and were aware of group allocation. The intervention comprises a 12-week meditation training in a big group that represents the social aspect of meditation. Data were analysed via a linear mixed effect model and intention to treat. Statistically significant results were obtained for global score of CORE-OM (β = −0.20 [−0.30; −0.10], p = 0.0002), FFMQ (β = 0.20 [0.12; −0.28], p < 0.0001), SWLS (β = 1.43 [0.42; 2.45], p = 0.006), positive PANAS (β = 1.99 [0.95; 3.04], p = 0.0002), negative PANAS (β = −1.67 [−2.92; −0.43], p = 0.009), PSS (β = −2.98 [−4.25; −1.71], p < 0.0001), WEMWBS (β = 4.38 [2.93; 5.83], p < 0.0001) and SHS (β = 1.43 [0.42; 2.45], p = 0.006). Our intervention is causally associated with an improvement of the psychological functioning and hence can be considered as a preventive measure that may potentially reduce the risk of developing psychological problems and improve the subject’s general well-being. Given the voluntary recruitment, our inference only applies to those individuals who have decided to experience meditation as a way to well-being and not to a random person from the general population.

scholarly journals IMPROVEMENT IN FINE MOTOR CONTROL IN DEMENTIA ELDERLY FROM A COMPUTERIZED TOUCHSCREEN TRAINING PROGRAM

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S910-S910
Author(s):  
W Quin Yow ◽  
Hui-Ching Chen ◽  
Tharshini Lokanathan
Keyword(s):  
Cognitive Abilities ◽  
Intervention Program ◽  
Cognitive Intervention ◽  
Finger Tapping ◽  
Fine Motor ◽  
Linear Mixed Effect Model ◽  
Mixed Effect ◽  
Motor Movement ◽  
Healthy Elderly ◽  
Moderate Dementia

Abstract Dementia, a prevalent ageing disease, affects both the higher brain function and motor function, particularly finger movements (Chan, Haber, Drew, & Park, 2014). Task-based finger-tapping speed on a touchscreen device has been used as an assessment criterion to identify patients with deteriorating cognitive abilities (Gualtieri & Johnson, 2005; Cipriani, Bianchetti, & Trabucchi, 2006). As part of a larger project, we designed a computerized cognition intervention program and examined whether the intervention program would improve the finger-tapping speed of the dementia vis-à-vis the cognitively-healthy elderly. Ten mild-to-moderate dementia elderly (aged 83± 5.6) and 8 cognitively healthy elderly (aged 78±6.1) participated in a computerized intervention program where they played cognitive games on touch-screen tablet for about 30-45 minutes per session over two weeks. Participants’ touch interaction data over six sessions were collected and analyzed. Using a linear mixed-effect model for analysis, we found that in the 1st session, the touch performance of the dementia elderly was significantly worse than that of the cognitively-healthy elderly (b=-0.172, Z=-2.311, p&lt;.05). By the 6th session, the dementia elderly had significantly improved their touch performance (b=-0.171, Z= -8.042, p&lt;.001) such that their touch performance was now comparable to the cognitively-healthy elderly (b=-0.064, Z=-0.874, p=.393). Overall, our preliminary results suggested that after participating in 6 sessions of our computerized cognitive intervention program, the dementia elderly showed significant improvement in their fine motor movement as measured by their finger-tapping speed. The improved finger-tapping speed serves as a first step toward slowing down the cognitive decline of the dementia elderly.

Efficacy of Crisis Intervention

Crisis ◽  
1999 ◽  
Vol 20 (2) ◽  
pp. 78-85 ◽  
Author(s):  
Thomas Reisch ◽  
Petra Schlatter ◽  
Wolfgang Tschacher
Keyword(s):  
Crisis Intervention ◽  
Intervention Program ◽  
Suicide Ideation ◽  
Indirect Evidence ◽  
Well Being ◽  
Term Therapy ◽  
Contributing Factors ◽  
Step Therapy ◽  
Long Term Therapy ◽  
The Impact

This study assesses the efficacy of the treatment approach implemented in the Bern Crisis Intervention Program, where particular emphasis is placed on the remediation of suicide ideation and suicidal behavior, and depression, fear, and phobia are generally considered to be contributing factors. Four questionnaires addressing psychopathology, emotional well-being, social anxiety, and personality were administered prior to and after the treatment of 51 patients over a period of 2 to 3 weeks. The reduction of symptoms contributing to suicidal ideation and behavior was interpreted as indirect evidence of an antisuicidal effect of the program. Significant improvements were found in the psychopathology ratings, with depression and anxiety showing the largest reductions. The impact on personality and social phobia, however, was only moderate, and on average patients still exhibited symptoms after attending the program. This residual symptomatology points to the necessity of introducing a two-step therapy approach of intensive intervention targeted at the precipitating causes of the crisis, augmented by long-term therapy to treat underlying problems.

A Pilot Study on the Efficacy of Volunteer Mentorship for Young Adults With Self-Harm Behaviors Using a Quasi-Experimental Design

Crisis ◽  
2016 ◽  
Vol 37 (6) ◽  
pp. 415-426 ◽  
Author(s):  
Yik-Wa Law ◽  
Paul S. F. Yip ◽  
Carmen C. S. Lai ◽  
Chi Leung Kwok ◽  
Paul W. C. Wong ◽  
...  
Keyword(s):  
Experimental Design ◽  
Suicide Ideation ◽  
Intervention Group ◽  
Well Being ◽  
Control Group ◽  
Treatment As Usual ◽  
Prevention Services ◽  
Quasi Experimental ◽  
Self Harm ◽  
Volunteer Support

Abstract. Background: Studies have shown that postdischarge care for self-harm patients is effective in reducing repeated suicidal behaviors. Little is known about whether volunteer support can help reduce self-harm repetition and improve psychosocial well-being. Aim: This study investigated the efficacy of volunteer support in preventing repetition of self-harm. Method: This study used a quasi-experimental design by assigning self-harm patients admitted to the emergency departments to an intervention group with volunteer support and treatment as usual (TAU) for 9 months and to a control group of TAU. Outcome measures include repetition of self-harm, suicidal ideation, hopelessness, and level of depressive and anxiety symptoms. Results: A total of 74 cases were recruited (38 participants; 36 controls). There were no significant differences in age, gender, and clinical condition between the two groups at the baseline. The intervention group showed significant improvements in hopelessness and depressive symptoms. However, the number of cases of suicide ideation and of repetition of self-harm episodes was similar for both groups at the postintervention period. Conclusion: Postdischarge care provided by volunteers showed significant improvement in hopelessness and depression. Volunteers have been commonly involved in suicide prevention services. Further research using rigorous methods is recommended for improving service quality in the long term.

The Unique Contribution of Positive Orientation to Optimal Functioning

2012 ◽  
Vol 17 (1) ◽  
pp. 44-54 ◽  
Author(s):  
Guido Alessandri ◽  
Gian Vittorio Caprara ◽  
John Tisak
Keyword(s):  
Psychological Functioning ◽  
Well Being ◽  
Unique Contribution ◽  
Critical Component ◽  
Positive Orientation ◽  
Cross Sectional ◽  
Common Mode ◽  
Optimal Functioning

Literature documents that the judgments people hold about themselves, their life, and their future are important ingredients of their psychological functioning and well-being, and are commonly related to each other. In this paper, results from a large cross-sectional sample (N = 1,331, 48% males) are presented attesting to the hypothesis that evaluations about oneself, one’s life, and one’s future rest on a common mode of viewing experiences named “Positive Orientation.” These results corroborate the utility of the new construct as a critical component of individuals’ well functioning.

scholarly journals Determinants of participation and quality of life of young adults with cerebral palsy: longitudinal approach and comparison with the general population – SPARCLE 3 study protocol

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Catherine Arnaud ◽  
Carine Duffaut ◽  
Jérôme Fauconnier ◽  
Silke Schmidt ◽  
Kate Himmelmann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Cerebral Palsy ◽  
Young People ◽  
General Population ◽  
Transition Period ◽  
Well Being ◽  
Personal Factors ◽  
The Impact

Abstract Background Effective inclusion in society for young people with disabilities is increasingly seen as generating opportunities for self-development, and improving well-being. However, significant barriers remain in the vast majority of activities meaningful for young adults. Research argues that various personal (disabilities, health) and environmental (access to the resources needed, accessible environment, discrimination, lack of personal economic independence) factors contribute to limited participation. However, previous studies conducted in young people with cerebral palsy (CP) mainly investigated the transition period to adulthood, and did not fully consider the whole range of impairment severity profiles or environmental barriers. In this study, we will use the follow-up of the SPARCLE cohort and a comparison group from the general population (1) to investigate the impact of the environment on participation and quality of life of young adults with CP, (2) to determine predictors of a successful young adulthood in educational, professional, health and social fields, (3) to compare quality of life and frequency of participation in social, work and recreational activities with the general population, (4) to document on participation and quality of life in those with severe disabilities. Methods The SPARCLE3 study has a combined longitudinal and cross-sectional design. Young adults with CP aged 22 to 27 years in 6 European regions previously enrolled in the SPARCLE cohort or newly recruited will be invited to self-complete a comprehensive set of questionnaires exploring participation (daily life and discretionary activities), health-related quality of life, body function, personal factors (health, personal resources), and contextual factors (availability of needed environmental items, family environment, services provision) during home visits supervised by trained researchers. Proxy-reports or adapted questionnaires will be used for those with the most severe impairments. The recruitment of a large group from the general population (online survey) will enable to identify life areas where the discrepancies between young people with CP and their able-bodied peers are the most significant. Discussion This study will help identify to what extent disabilities and barriers in environment negatively affect participation and quality of life, and how previous valued experiences during childhood or adolescence might modulate these effects.

Understanding Effects of Tourism on Residents: A Contingent Subjective Well-Being Approach

2021 ◽  
pp. 004728752098891
Author(s):  
Kreg Lindberg ◽  
Ian E. Munanura ◽  
Chad Kooistra ◽  
Mark D. Needham ◽  
Ladan Ghahramani
Keyword(s):  
General Population ◽  
Population Growth ◽  
Population Survey ◽  
Well Being ◽  
County Level ◽  
Subjective Well Being ◽  
General Population Survey ◽  
Environment Domain ◽  
Perceived Impacts ◽  
Practical Implications

Research regarding tourism’s effect on the subjective well-being (SWB) of destination residents has provided important insight, but it generally has relied on indirect analyses and diverse measures. This study used livability theory and a novel contingent SWB method in which respondents directly reported anticipated SWB effects. This method is exploratory, but it provides greater confidence in causal relationships. Results from a general population survey in Oregon (USA) suggested the method functioned as intended. County-level population growth and visitor intensity predicted perceived current impacts of tourism. In turn, perceived impacts predicted change in SWB contingent on a vignette reflecting a 20% increase in tourists. Across all individuals and counties, average SWB changes were negative for the environment domain and positive for other domains. Practical implications are discussed, with the most positive SWB effects from tourism development expected to occur in counties with low visitor intensity, especially those with low population growth.

scholarly journals MegaLMM: Mega-scale linear mixed models for genomic predictions with thousands of traits

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Daniel E. Runcie ◽  
Jiayi Qu ◽  
Hao Cheng ◽  
Lorin Crawford
Keyword(s):  
Genomic Prediction ◽  
Large Scale ◽  
Mixed Model ◽  
Human Genetics ◽  
Linear Mixed Effect Model ◽  
Mixed Effect ◽  
Statistical Framework ◽  
Effect Model ◽  
Plant Data ◽  
Genetic Value

AbstractLarge-scale phenotype data can enhance the power of genomic prediction in plant and animal breeding, as well as human genetics. However, the statistical foundation of multi-trait genomic prediction is based on the multivariate linear mixed effect model, a tool notorious for its fragility when applied to more than a handful of traits. We present , a statistical framework and associated software package for mixed model analyses of a virtually unlimited number of traits. Using three examples with real plant data, we show that can leverage thousands of traits at once to significantly improve genetic value prediction accuracy.

scholarly journals Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gregory R. Keele ◽  
Jeremy W. Prokop ◽  
Hong He ◽  
Katie Holl ◽  
John Littrell ◽  
...  
Keyword(s):  
Complex Traits ◽  
Genetic Model ◽  
Association Studies ◽  
Model Systems ◽  
Linear Mixed Effect Model ◽  
Genome Wide Association Studies ◽  
Tubulointerstitial Injury ◽  
Heritable Variation ◽  
Mixed Effect

AbstractChronic kidney disease (CKD), which can ultimately progress to kidney failure, is influenced by genetics and the environment. Genes identified in human genome wide association studies (GWAS) explain only a small proportion of the heritable variation and lack functional validation, indicating the need for additional model systems. Outbred heterogeneous stock (HS) rats have been used for genetic fine-mapping of complex traits, but have not previously been used for CKD traits. We performed GWAS for urinary protein excretion (UPE) and CKD related serum biochemistries in 245 male HS rats. Quantitative trait loci (QTL) were identified using a linear mixed effect model that tested for association with imputed genotypes. Candidate genes were identified using bioinformatics tools and targeted RNAseq followed by testing in a novel in vitro model of human tubule, hypoxia-induced damage. We identified two QTL for UPE and five for serum biochemistries. Protein modeling identified a missense variant within Septin 8 (Sept8) as a candidate for UPE. Sept8/SEPTIN8 expression increased in HS rats with elevated UPE and tubulointerstitial injury and in the in vitro hypoxia model. SEPTIN8 is detected within proximal tubule cells in human kidney samples and localizes with acetyl-alpha tubulin in the culture system. After hypoxia, SEPTIN8 staining becomes diffuse and appears to relocalize with actin. These data suggest a role of SEPTIN8 in cellular organization and structure in response to environmental stress. This study demonstrates that integration of a rat genetic model with an environmentally induced tubule damage system identifies Sept8/SEPTIN8 and informs novel aspects of the complex gene by environmental interactions contributing to CKD risk.

scholarly journals Validity and reliability of the Self-Care Activities Screening Scale (SASS-14) during COVID-19 lockdown

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Martín Martínez ◽  
Elkin O. Luis ◽  
Edwin Yair Oliveros ◽  
Pablo Fernández-Berrocal ◽  
Ainize Sarrionandia ◽  
...  
Keyword(s):  
General Population ◽  
Perceived Stress ◽  
Convergent Validity ◽  
Self Care ◽  
Internal Validity ◽  
Well Being ◽  
Validity And Reliability ◽  
Good Reliability ◽  
Confirmatory Factor Analyses ◽  
Health Consciousness

Abstract Background In a context where there is no treatment for the current COVID-19 virus, the combination of self-care behaviours together with confinement, are strategies to decrease the risk of contagion and remain healthy. However, there are no self-care measures to screen self-care activities in general population and which, could be briefly in a lockdown situation. This research aims to build and validate a psychometric tool to screen self-care activities in general population. Methods Firstly, an exploratory factor analysis was performed in a sample of 226 participants to discover the underlying factorial structure and to reduce the number of items in the original tool into a significant pool of items related to self-care. Later a confirmatory factor analyses were performed in a new sample of 261 participants to test for the fit and goodness of factor solutions. Internal validity, reliability, and convergent validity between its score with perceived stress and psychological well-being measures were examined on this sample. Results The exploratory analyses suggested a four-factor solution, corresponding to health consciousness, nutrition and physical activity, sleep, and intra-personal and inter-personal coping skills (14 items). Then, the four-factor structure was confirmed as the best model fit for self-care activities. The tool demonstrated good reliability, predictive validity of individuals’ perception of coping with COVID-19 lockdown, and convergent validity with well-being and perceived stress. Conclusions This screening tool could be helpful to address future evaluations and interventions to promote healthy behaviours. Likewise, this tool can be targeted to specific population self-care’s needs during a scalable situation.

scholarly journals Limited not lazy: a quasi-experimental secondary analysis of evidence quality evaluations by those who hold implausible beliefs

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Kristy A. Martire ◽  
Bethany Growns ◽  
Agnes S. Bali ◽  
Bronte Montgomery-Farrer ◽  
Stephanie Summersby ◽  
...  
Keyword(s):  
Secondary Analysis ◽  
Past Research ◽  
Linear Mixed Effect Model ◽  
High Quality ◽  
Mixed Effect ◽  
High Quality Evidence ◽  
Effect Model ◽  
Evidence Quality ◽  
Quasi Experimental ◽  
Quality Evidence

AbstractPast research suggests that an uncritical or ‘lazy’ style of evaluating evidence may play a role in the development and maintenance of implausible beliefs. We examine this possibility by using a quasi-experimental design to compare how low- and high-quality evidence is evaluated by those who do and do not endorse implausible claims. Seven studies conducted during 2019–2020 provided the data for this analysis (N = 746). Each of the seven primary studies presented participants with high- and/or low-quality evidence and measured implausible claim endorsement and evaluations of evidence persuasiveness (via credibility, value, and/or weight). A linear mixed-effect model was used to predict persuasiveness from the interaction between implausible claim endorsement and evidence quality. Our results showed that endorsers were significantly more persuaded by the evidence than non-endorsers, but both groups were significantly more persuaded by high-quality than low-quality evidence. The interaction between endorsement and evidence quality was not significant. These results suggest that the formation and maintenance of implausible beliefs by endorsers may result from less critical evidence evaluations rather than a failure to analyse. This is consistent with a limited rather than a lazy approach and suggests that interventions to develop analytical skill may be useful for minimising the effects of implausible claims.

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