scholarly journals Comparison of Mean Platelet Counts in Preterm Infants with and without Retinopathy of Prematurity

Author(s):  
Zi Di Lim ◽  
Edwin Pheng ◽  
Evelyn Tai Li Min ◽  
Hans Van Rostenberghe ◽  
Ismail Shatriah

Platelets are a primary source of pro- and anti-angiogenic cytokines. However, the evidence of their role in retinopathy of prematurity (ROP) is controversial. This retrospective study aimed to compare mean weekly platelet counts between infants with and without ROP over the first 6 weeks of life. A total of 93 infants matched by gestational age and birth weight were recruited (31 with ROP, 62 without ROP). Weekly mean platelet counts and other related risk factors were documented. The repeated measure analysis of variance (ANOVA) and the repeated measure analysis of covariance (ANCOVA) were used to compare mean platelet counts over time between the two groups, with and without adjusting for confounders. We found significant differences in the weekly mean platelet counts of infants with and without ROP over the first 6 weeks of life (p = 0.002). These differences disappeared after adjusting for covariates (p = 0.489). Lower mean platelet counts in ROP infants are not directly related to ROP, but rather to the presence of other risk factors for ROP, such as culture-proven sepsis, blood transfusion and bronchopulmonary dysplasia.

2021 ◽  
Vol 45 (6) ◽  
pp. 1079-1090
Author(s):  
Young Sam Oh ◽  
Na Kyoung Song

Objectives: This research examines social distancing changes over time, and by region of the United States after the COVID-19 pandemic began. Methods: We utilized information on social distancing from the Google Community Mobility Reports. We performed one-way repeated-measure analysis of variance (RM-ANOVA) to examine the overall changes in the 6 types of social distancing from baseline to the 12-week follow-up (March 1 to May 24, 2020). We applied a 2-way RM-ANOVA to evaluate the effects of time and 4 regions on social distancing. Results: According to one-way RM-ANOVA results, social distancing tended to increase until Time 3 (March 30 to April 12) and 4 (April 13 to April 26), before decreasing again, regardless of the area. The 2-way RM-ANOVA results revealed that the social distancing variations in the 6 area types over time were statistically significant in each region, along with the interaction of regions and time. Compared to other regions, social distancing was the highest in the Northeast area, except in park areas. Conclusions: We found that social distancing can be influenced not only by contagion changes, but also by regional differences. Understanding the features of social distancing can play a significant role in helping society build a promising COVID-19 prevention model.


1997 ◽  
Vol 12 (5) ◽  
pp. 259-262
Author(s):  
L Lykouras ◽  
M Markianos ◽  
Y Papakostas ◽  
D Malliaras

SummaryThe thyrotropin (TSH) and prolactin (PRL) responses to protirelin (TRH) were studied in 62 female unipolar depressive patients, 24 delusional (psychotic) and 38 nondelusional (Diagnostic and Statistical Manual [DSM]-III-R criteria). The TSH response to TRH was blunted (≤6 μlU/mL) in ten of the 24 delusional (41.6%) and in 18 of the 38 nondelusional (47.4%) patients, the difference being not significant. The TSH and PRL responses to TRH, calculated as area under the curve, were not different between the two groups. Similar results were obtained when the response patterns were compared by repeated measure analysis of covariance.


Author(s):  
Samer Mheissen ◽  
Haris Khan ◽  
Mohammed Almuzian ◽  
Emad Eddin Alzoubi ◽  
Nikolaos Pandis

Summary Background In orthodontic trials, longitudinal designs with multiple outcome measurements over time are common. The aim of this epidemiological study was to examine whether optimal statistical analysis approaches have been used in longitudinal orthodontic trials. Methods Pubmed was searched in August 2021 for longitudinal orthodontic trials with at least three time points of outcome assessment published in the 2017–20 period. Study selection and data extraction were done independently and in duplicate. The analysis approaches undertaken were tabulated and associations between study characteristics and the use of optimal analysis or not were assessed using Fisher’s exact test and logistic regression. Results One hundred forty-seven out of 563 unique records were deemed eligible for inclusion. Only 26.50% of these trials used an optimal statistical analysis for longitudinal data where the data structure is accounted for. None of the study characteristics except the statistical significance of the results were associated with the appropriateness of the statistical analysis. The odds of significant results in studies with suboptimal analyses were higher than that in studies with optimal longitudinal analyses (odds ratio: 3.48, 95% confidence interval: 1.62, 7.46, P = 0.001). For the studies with optimal analysis, the most frequent test was repeated-measure analysis of variance (RM-ANOVA). The reporting of the statistical analysis section was suboptimal in the majority of the trials. Conclusion Most longitudinal orthodontic trials are not analysed using optimal statistical approaches. Inferences and interpretation of their results are likely to be compromised.


2019 ◽  
Vol 10 (1) ◽  
pp. 9-17
Author(s):  
Martina Đodan ◽  
Tomislav Dubravac ◽  
Sanja Perić

Background and Purpose: Recently raised questions on adaptability of native tree species to climate changes pointed to Douglas-fir as a species suitable for rapid reforestation and increase of stand resistance. The first results on provenance research need to be confirmed in later stages of stand development, so the paper answers the following two questions: (i) are there differences in growth of 14 Douglas-fir provenances still in the fifth decade of stand development, and (ii) which provenances should be used and which omitted from further use in the hilly area of Croatia? Materials and Methods: Productivity of 14 provenances was evaluated on the basis of height, diameter at breast height and volume in the 46th year after planting. Growth dynamics was also statistically analysed using a repeated measure analysis of variance, for which purpose we partially used published data from the 2010. Results: The analysis excluded Castle Rock and Shady Cove (Oregon) provenances due to their low values of all analysed growth indicators, as well as Castle Rock, Elma and Hvidilde provenances due to their high values. Average values of tree volume ranged from 0.53 m3 (Shady Cove) to 2.05 m3 (Castle Rock), while the tallest trees belonged to Elma provenance (29.6 m). Conclusions: Different growth dynamics of provenances were confirmed for later development stage, so further monitoring is still required. Clear guidelines for the selection of provenances for practical forestry distinguish provenances from lower altitudes of the State of Washington, Denmark and Bulgaria as the most productive. Shady Cove and Salmon Arm provenances are not advised to be used in the future.


2001 ◽  
Vol 92 (1) ◽  
pp. 99-106 ◽  
Author(s):  
Gary C. Galbraith ◽  
Bernadine Bagasan ◽  
Jane Sulahian

The human brainstem frequency-following response reflects neural activity to periodic auditory stimuli. Responses were simultaneously recorded from one vertically oriented and three horizontally oriented electrode derivations. Nine participants each received a total of 16,000 tone repetitions, 4,000 for each of four stimulus frequencies: 222, 266, 350, and 450 Hz. The responses were digitally filtered, quantified by correlation and spectral analysis, and statistically evaluated by repeated measure analysis of variance. While the various horizontal derivation responses did not differ from each other in latency (values tightly clustered around M = 2.60 msec), the vertical derivation response occurred significantly later ( M = 4.38 msec). The smaller latency for the horizontal responses suggests an origin within the acoustic nerve, while the larger latency for the vertical response suggests a central brainstem origin. The largest response amplitude resulted from gold “tiptrode” electrodes placed in each auditory meatus, suggesting that this electrode derivation provided the most accurate (noninvasive) assessment of short-latency events originating at the level of the auditory nerve.


2010 ◽  
Vol 110 (1) ◽  
pp. 224-228 ◽  
Author(s):  
Valeria Zanna ◽  
Ludovica Filippucci ◽  
Maria Chiara Castiglioni

2015 ◽  
Vol 18 (3) ◽  
pp. 621-625 ◽  
Author(s):  
G. Piccione ◽  
M. Rizzo ◽  
F. Arfuso ◽  
C. Giannetto ◽  
S. Di Pietro ◽  
...  

Abstract During early post-partum period both neonatal foals and peripartum mares are most susceptible to diseases. The aim of this study was to establish physiologic modifications of leukogram during the first month after foaling in mares and their newborn foals. To this end blood samples were collected from nine mares and nine foals (T0-T10), every three days from the 1st day until the 30th day after foaling. Samples were analysed for white blood cell (WBC) count and differential leucocyte counts. Two-way repeated measure analysis of variance (ANOVA) showed, in postpartum mares WBC showed significant higher values at T0 (9.02±0.76) in respect to other time points, and at T2 (8.08±0.53) and T3 (7.92±0.59) compared to T1 (6.98±0.43), whereas in foals lower WBC values at T0 (6.11±0.49) compared to other experimental periods except T1 (6.90±0.94), and at T1 compared to T8 (7.95±0.61) and T10 (7.90±0.36) were observed. The differential leucocyte counts showed significant modifications in the percentage of neutrophils (π<0.001) and lymphocytes (p<0.001) both in postpartum mares and in foals during the experimental period. Furthermore ANOVA showed significant differences between postpartum mares and foals (P<0.01) in all studied parameters, and between postpartum mares and control mares in WBC and neutrophils values. The obtained results provide suitable information about the influence of foaling on leukogram of periparturient mares and reveal WBC dynamics in newborn foals during the first month post-partum.


2021 ◽  
Vol 9 (2) ◽  
pp. 290-298
Author(s):  
Rian Tri Prayogo ◽  
Sendy Mohamad Anugrah ◽  
Ardhika Falaahudin ◽  
Dody Tri Iwandana ◽  
Rifqi Festiawan

Pembatasan kegiatan masyarakat akibat penyebaran virus covid-19 telah mengubah olahraga di Indonesia sehingga memaksa para atlet untuk melakukan latihan mandiri di tempat tinggalnya masing-masing dengan program latihan yang dibuat oleh para pelatihnya. Tujuan penelitian ini adalah membandingkan kapasitas aerobik, aspek kelincahan, dan daya tahan otot lokal atlet pencak silat sebelum dan sesudah masa latihan mandiri. Metode penelitian yang digunakan adalah deskritptif dengan melibatkan 12 atlet pencak silat putra kategori tanding Kabupaten Karawang. Hasil penelitian menunjukan bahwa terjadi penurunan signifikan pada kapasitas aerobik (p= 0.025) dan performa kelincahan (0.042) namun pada daya tahan otot lokal tidak terdapat perbedaan. Kesimpulan penelitian ini adalah terjadi penurunan pada kapasitas aerobik dan aspek kelincahan pada atlet pencak silat Kabupaten Karawang setelah masa latihan di tempat tinggalnya masing-masing akibat dari pemberlakukan pembatasan kegiatan masyarakat (PPKM), namun pada komponen daya tahan otot-otot lokal tidak terdapat perubahan.The sports activity of badminton and responses to changes in blood uric acid at productive age AbstractThis study aims to determine whether there was a response to changes in uric acid levels due to the physical activity of badminton. The design of this study is a quasi-experimental. The sample used in this study was eight respondents with certain criteria. Treat physical activity twice on different days with 4 measurements of uric acid levels. The method of this study is repeated measure analysis. When subjects are measured repeatedly, requiring fewer subjects per experiment, then repeated measures analysis can be used. The results showed that the treatment of badminton had a significant effect on changes in uric acid levels with a probability value of 0,038. These results were obtained by using the Greenhouse-Geisser test where the assumptions of normality and homogeneity were satisfied. From the marginal test results using pairwise comparisons, there was a significant difference in the average uric acid levels at 15 minutes after exercise and 9 hours the following day, where there was a decrease of 1.169 mg/dl. Badminton can reduce uric acid levels, which is indicated by a decrease of 0.15 mg/dl at 09.00 the next day compared to before exercise. Marginally, this decrease is not statistically significant, but regular badminton can be an option for physical activity for those who want to reduce uric acid levels.


The aim of this study was to determine and compare the effects of directions on the repeated sprint ability (RSA) with ball performance among university soccer players. Twenty soccer players representing a public university team compete in Malaysian Intervarsity tournament was recruited as study participants. Participants were assigned to two RSA tests with two different directions; i) Right-left-right (RLR) and ii) Left-right-left (LRL). Sprints time, fatigue index and strength of decrement score (Sdec) were compared between the two drills. Repeated measure analysis of variances (ANOVA) was conducted to determine the differences. Results showed no significant differences of were found for each sprints time and total time. However, FI and Sdec were found to be significantly lower during LRL. Future research is suggested to stress on the influences of ball controlling during the slides and turns at the markers on RSA performance.


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