scholarly journals Bioaccumulation, Biodistribution, Toxicology and Biomonitoring of Organofluorine Compounds in Aquatic Organisms

2021 ◽  
Vol 22 (12) ◽  
pp. 6276
Author(s):  
Dario Savoca ◽  
Andrea Pace

This review is a survey of recent advances in studies concerning the impact of poly- and perfluorinated organic compounds in aquatic organisms. After a brief introduction on poly- and perfluorinated compounds (PFCs) features, an overview of recent monitoring studies is reported illustrating ranges of recorded concentrations in water, sediments, and species. Besides presenting general concepts defining bioaccumulative potential and its indicators, the biodistribution of PFCs is described taking in consideration different tissues/organs of the investigated species as well as differences between studies in the wild or under controlled laboratory conditions. The potential use of species as bioindicators for biomonitoring studies are discussed and data are summarized in a table reporting the number of monitored PFCs and their total concentration as a function of investigated species. Moreover, biomolecular effects on taxonomically different species are illustrated. In the final paragraph, main findings have been summarized and possible solutions to environmental threats posed by PFCs in the aquatic environment are discussed.

2016 ◽  
Vol 42 (1) ◽  
pp. 87-101 ◽  
Author(s):  
Iwona Krzyżewska ◽  
Joanna Kyzioł-Komosińska ◽  
Czesława Rosik-Dulewska ◽  
Justyna Czupioł ◽  
Patrycja Antoszczyszyn-Szpicka

AbstractThe aim of this paper is to present characteristics, toxicity and environmental behavior of nanoparticles (NPs) (silver, copper, gold, zinc oxide, titanium dioxide, iron oxide) that most frequently occur in consumer products. In addition, NPs are addressed as the new aquatic environmental pollutant of the 21stcentury. NPs are adsorbed onto particles in the aquatic systems (clay minerals, fulvic and humic acids), or they can adsorb environmental pollutants (heavy metal ions, organic compounds). Nanosilver (nAg) is released from consumer products into the aquatic environment. It can threaten aquatic organisms with high toxicity. Interestingly, copper nanoparticles (Cu-NPs) demonstrate higher toxicity to bacteria and aquatic microorganisms than those of nanosilver nAg. Their small size and reactivity can cause penetration into the tissues and interfere with the metabolic systems of living organisms and bacterial biogeochemical cycles. The behavior of NPs is not fully recognized. Nevertheless, it is known that NPs can agglomerate, bind with ions (chlorides, sulphates, phosphates) or organic compounds. They can also be bound or immobilized by slurry. The NPs behavior depends on process conditions, i.e. pH, ionic strength, temperature and presence of other chemical compounds. It is unknown how NPs behave in the aquatic environment. Therefore, the research on this problem should be carried out under different process conditions. As for the toxicity, it is important to understand where the differences in the research results come from. As NPs have an impact on not only aquatic organisms but also human health and life, it is necessary to recognize their toxic doses and know standards/regulations that determine the permissible concentrations of NPs in the environment.


Author(s):  
Eduard Kompanets ◽  
◽  
Viktoria Lavrynenko ◽  

Ecosystems are subject to many human influences. The balance between species is disturbed due to interference with the aquatic environment. Due to environmental pollution, its impact on fish and other aquatic organisms changes. This affects ecosystem connections. Changes in the environment also change the adaptive capacity of fish, leading to impaired health. Also, there is a need to study the protective capabilities of fish from the naturally occurring opportunistic species Aeromonas hydrophila, which causes infections in them. In natural hydrobiocenoses, fish, as well as pathogens of its diseases (aeromonads) are components of food chains formed by evolution. Literature sources prove that aeromonads are normally present in microbial associations of benthic microflora as a normal saprophytic component of hydroecosystems. These bacteria feed on organic residues that are concentrated at the bottom of water bodies and perform a sanitary function, like other similar types of microorganisms. The health of fish depends on their ability to adapt to the environment. Usually in the wild, fish are rarely susceptible to disease. Local populations for a long time of coexistence have formed a certain balance with other species, including parasitic. The balance is reflected by a certain rate of abundance between species. Imbalance due to fishing from the reservoir, or, conversely, with an artificial increase in numbers, leads to changes in the aquatic environment. Changes in the habitat of fish affect themselves. Fish health is changing. In nature, such a disease as aeromonosis is an ecological concept. Violation of the ecological conditions of the species leads to stress, and reduced immunity in fish, leads to fish disease. In aeromonad infections with weak symptoms in carp, a decrease in biological parameters was observed: growth, body weight, fatness and survival (57.1%). The number of blood cells in diseased fish decreased, especially leukocytes and lymphocytes. The percentage of T- and B-lymphocytes in the blood of carp-infected carp increased. The introduction of the bacterium stimulated the immune response – an increase in the percentage of T-lymphocytes. The percentage of B cells did not increase significantly. In diseased fish, the percentage and number of low-activity T-lymphocytes increased, which corresponded to the presence of an immune response to the bacterium. The values of antibacterial activity of blood serum (BASC) in both groups of fish did not change.


2020 ◽  
Vol 34 (7) ◽  
pp. 804-813 ◽  
Author(s):  
Jean-Michel Robichaud ◽  
Mélodie Roy ◽  
Francis Ranger ◽  
Geneviève A. Mageau

1995 ◽  
Vol 31 (10) ◽  
pp. 73-84 ◽  
Author(s):  
T. M. Iversen

The main environmental problems associated with fish farming in Denmark are attributable to the dam, the “dead reach” and nutrient and organic matter discharge. The environmental regulation of fish farming in Denmark started with the Environmental Protection Act of 1974, the Statutory Order of 1985 forbidding wet feed, and the Action Plan on the Aquatic Environment of 1987. In the case of freshwater fish farms, the latter was implemented through the measures stipulated in the 1989 Statutory Order on Fish Farms. The impact of Danish legislative measures to reduce and regulate the environmental effects of freshwater fish farms can be summarized as follows: - the number of fish farms has been reduced from about 800 in 1974 to about 500 at present; - production has tripled since 1974 and has been stable since 1989; - a change from wet to dry feed has reduced the environmental impact of the farms; - the national goals of the Action Plan on the Aquatic Environment of 1987 for reducing fish farm discharges of organic matter, nitrogen and phosphorus have been fulfilled. The main remaining problems are that: - the local impact of fish farms on downstream stream quality is still much too high in about 15% of cases; - the problem of the passage of migrating invertebrates and fish is still unsolved at some farms; - the problems posed by “dead reaches” are still unsolved. It is concluded that sustainable fish farming is possible in Denmark, but with the present technology production will have to be significantly reduced.


2020 ◽  
Vol 24 (21) ◽  
pp. 2475-2497
Author(s):  
Andrea Verónica Rodríguez-Mayor ◽  
German Jesid Peralta-Camacho ◽  
Karen Johanna Cárdenas-Martínez ◽  
Javier Eduardo García-Castañeda

Glycoproteins and glycopeptides are an interesting focus of research, because of their potential use as therapeutic agents, since they are related to carbohydrate-carbohydrate, carbohydrate-protein, and carbohydrate-lipid interactions, which are commonly involved in biological processes. It has been established that natural glycoconjugates could be an important source of templates for the design and development of molecules with therapeutic applications. However, isolating large quantities of glycoconjugates from biological sources with the required purity is extremely complex, because these molecules are found in heterogeneous environments and in very low concentrations. As an alternative to solving this problem, the chemical synthesis of glycoconjugates has been developed. In this context, several methods for the synthesis of glycopeptides in solution and/or solid-phase have been reported. In most of these methods, glycosylated amino acid derivatives are used as building blocks for both solution and solid-phase synthesis. The synthetic viability of glycoconjugates is a critical parameter for allowing their use as drugs to mitigate the impact of microbial resistance and/or cancer. However, the chemical synthesis of glycoconjugates is a challenge, because these molecules possess multiple reaction sites and have a very specific stereochemistry. Therefore, it is necessary to design and implement synthetic routes, which may involve various protection schemes but can be stereoselective, environmentally friendly, and high-yielding. This review focuses on glycopeptide synthesis by recapitulating the progress made over the last 15 years.


J ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 116-130
Author(s):  
Daria Smolova ◽  
Avi Friedman

Current social and environmental challenges have led to the rethinking of residential designs. Global warming, food insecurity, and, as a result, costly fresh produce are some of the causes of the reconsideration. Moreover, with obligatory isolation following the global COVID-19 pandemic, some are realizing the importance of nature and air quality in homes. This paper explores the potential integration of indoor living walls (ILWs) in Canadian homes for agricultural and air purification purposes. By reviewing a number of case studies, this paper investigates how the development of such walls can alter the traditional food production chain, while reducing environmental threats. The findings show that current indoor living wall practices can be transformed into a useful source of fresh food, and, to some degree, alter traditional food supply. They can also help in creating inexpensive methods of air purification.


Author(s):  
Emma-Jane Goode ◽  
Eirian Thomas ◽  
Owen Landeg ◽  
Raquel Duarte-Davidson ◽  
Lisbeth Hall ◽  
...  

AbstractEvery year, numerous environmental disasters and emergencies occur across the globe with far-reaching impacts on human health and the environment. The ability to rapidly assess an environmental emergency to mitigate potential risks and impacts is paramount. However, collating the necessary evidence in the early stages of an emergency to conduct a robust risk assessment is a major challenge. This article presents a methodology developed to help assess the risks and impacts during the early stages of such incidents, primarily to support the European Union Civil Protection Mechanism but also the wider global community in the response to environmental emergencies. An online rapid risk and impact assessment tool has also been developed to promote enhanced collaboration between experts who are working remotely, considering the impact of a disaster on the environment and public health in the short, medium, and long terms. The methodology developed can support the appropriate selection of experts and assets to be deployed to affected regions to ensure that potential public health and environmental risks and impacts are mitigated whenever possible. This methodology will aid defensible decision making, communication, planning, and risk management, and presents a harmonized understanding of the associated impacts of an environmental emergency.


Author(s):  
Nadine T. Hillock ◽  
Tracy L. Merlin ◽  
Jonathan Karnon ◽  
John Turnidge ◽  
Jaklin Eliott

Abstract Background The frameworks used by Health Technology Assessment (HTA) agencies for value assessment of medicines aim to optimize healthcare resource allocation. However, they may not be effective at capturing the value of antimicrobial drugs. Objectives To analyze stakeholder perceptions regarding how antimicrobials are assessed for value for reimbursement purposes and how the Australian HTA framework accommodates the unique attributes of antimicrobials in cost-effectiveness evaluation. Methods Eighteen individuals representing the pharmaceutical industry or policy-makers were interviewed. Interviews were transcribed verbatim, coded, and thematically analyzed. Results Key emergent themes were that reimbursement decision-making should consider the antibiotic spectrum when assessing value, risk of shortages, the impact of procurement processes on low-priced comparators, and the need for methodological transparency when antimicrobials are incorporated into the economic evaluation of other treatments. Conclusions Participants agreed that the current HTA framework for antimicrobial value assessment is inadequate to properly inform funding decisions, as the contemporary definition of cost-effectiveness fails to explicitly incorporate the risk of future resistance. Policy-makers were uncertain about how to incorporate future resistance into economic evaluations without a systematic method to capture costs avoided due to good stewardship. Lacking financial reward for the benefits of narrower-spectrum antimicrobials, companies will likely focus on developing broad-spectrum agents with wider potential use. The perceived risks of shortages have influenced the funding of generic antimicrobials in Australia, with policy-makers suggesting a willingness to pay more for assured supply. Although antibiotics often underpin the effectiveness of other medicines, it is unclear how this is incorporated into economic models.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Brian J. Johnson ◽  
Amy Robbins ◽  
Narayan Gyawali ◽  
Oselyne Ong ◽  
Joanne Loader ◽  
...  

AbstractKoala populations in many areas of Australia have declined sharply in response to habitat loss, disease and the effects of climate change. Koalas may face further morbidity from endemic mosquito-borne viruses, but the impact of such viruses is currently unknown. Few seroprevalence studies in the wild exist and little is known of the determinants of exposure. Here, we exploited a large, spatially and temporally explicit koala survey to define the intensity of Ross River Virus (RRV) exposure in koalas residing in urban coastal environments in southeast Queensland, Australia. We demonstrate that RRV exposure in koalas is much higher (> 80%) than reported in other sero-surveys and that exposure is uniform across the urban coastal landscape. Uniformity in exposure is related to the presence of the major RRV mosquito vector, Culex annulirostris, and similarities in animal movement, tree use, and age-dependent increases in exposure risk. Elevated exposure ultimately appears to result from the confinement of remaining coastal koala habitat to the edges of permanent wetlands unsuitable for urban development and which produce large numbers of competent mosquito vectors. The results further illustrate that koalas and other RRV-susceptible vertebrates may serve as useful sentinels of human urban exposure in endemic areas.


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