scholarly journals ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail

2020 ◽  
Vol 8 (2) ◽  
pp. 146 ◽  
Author(s):  
Xiaoyuan Wei ◽  
Tsungcheng Tsai ◽  
Joshua Knapp ◽  
Kristopher Bottoms ◽  
Feilong Deng ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Growth Performance ◽  
Rectal Swab ◽  
Average Daily Gain ◽  
Swine Production ◽  
Deficient Diet ◽  
Nursery Pigs ◽  
High Zinc ◽  
Daily Gain ◽  
Different Levels

Zinc has been very efficacious in reducing post-weaning diarrhea, whereas animal-derived peptides are suggested to improve the growth performance of weaned piglets. However, the combined effect of zinc and peptides on swine production and swine gut microbiota is still largely unknown. In this study, we followed 288 nursery pigs from the age of d30 to d60 to evaluate the growth performance and gut microbiota of weanling pigs subjected to different levels of a fish-porcine-microbial peptide cocktail (0.05%, 0.25%, and 0.5%) with or without the pharmaceutical level of zinc oxide (ZnO) (2500 ppm) supplementation in a nutrient-deficient diet. Rectal swab samples were collected from pigs with body weight (BW) approach average at each pen on d30, d42, and d60 to determine gut microbiota. Average daily gain (ADG) and BW in piglets fed high zinc (HZ) increased with increasing levels of peptide. The microbiota of the HZ group also diverged from those of the standard zinc (SZ) group from d30 to d60. Adding peptide did not alter community structure regardless of zinc supplementation. Collectively, these findings demonstrated that the pharmaceutical level of zinc as ZnO conditioned the gut community to the point where peptide could effectively restore growth performance in nursery pigs fed nutrient-deficient diets.

scholarly journals D-Galactose Induces Chronic Oxidative Stress and Alters Gut Microbiota in Weaned Piglets

2021 ◽  
Vol 12 ◽  
Author(s):  
Hui Han ◽  
Zemin Liu ◽  
Jie Yin ◽  
Jing Gao ◽  
Liuqin He ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gut Microbiota ◽  
Growth Performance ◽  
Relative Abundance ◽  
Average Daily Gain ◽  
Intestinal Morphology ◽  
Weaned Piglets ◽  
Chronic Oxidative Stress ◽  
Daily Gain ◽  
Different Levels

Oxidative stress commonly occurs in pig production, which can severely damage the intestinal function of weaned piglets. This study was conducted to investigate the effects of D-galactose with different levels used to induce chronic oxidative stress on growth performance, intestinal morphology and gut microbiota in weaned piglets. The results showed that addition of 10 and 20 g/kg BW D-galactose reduced average daily gain and average daily feed intake from the first to the third week. 10 g/kg BW D-galactose increased the concentration of serum MDA at the second and third week. 10 g/kg BW D-galactose significantly influenced the jejunal and ileal expressions of GPx1, CAT1, and MnSOD. The results of 16S rRNA sequencing showed that compared with the control, 10 and 20 g/kg BW D-galactose significantly decreased the relative abundance of Tenericutes, Erysipelotrichia, Erysipelotrichales, and Erysipelotrichaceae, while increased the relative abundance of Negativicutes, Selenomonnadales, and Veillonellaceae. The results indicated that treatment with 10 g/kg BW/day D-galactose for 3 weeks could induce chronic oxidative stress, reduce the growth performance and alter gut microbiota in weaned piglets.

scholarly journals Effects of Fumonisin-Contaminated Corn on Growth Performance of 9 to 28 kg Nursery Pigs

Toxins ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 604
Author(s):  
Zhong-Xing Rao ◽  
Mike D. Tokach ◽  
Jason C. Woodworth ◽  
Joel M. DeRouchey ◽  
Robert D. Goodband ◽  
...  
Keyword(s):  
Growth Performance ◽  
Linear Response ◽  
Animal Feed ◽  
Average Daily Gain ◽  
Fumonisin B1 ◽  
Nursery Pigs ◽  
Feed Production ◽  
Dietary Treatments ◽  
Daily Gain ◽  
Effect Of Feeding

Fumonisin contamination in corn is an emerging issue in animal feed production. Fumonisin disrupts the metabolism of sphingolipids and reduces growth performance. This experiment was conducted to determine the effect of feeding fumonisin-contaminated corn on growth performance and sphinganine (SA) to sphingosine (SO) ratios of 9 to 28 kg pigs. A total of 350 pigs, were used with 5 pigs/pen and 14 pens/treatment. Dietary treatments contained fumonisin-contaminated corn (50 mg/kg of fumonisin B1 + B2) blended with low fumonisin corn (10 mg/kg of fumonisin B1 + B2) to provide dietary fumonisin concentrations of 7.2, 14.7, 21.9, 32.7, and 35.1 mg/kg. From day 0 to 28, increasing fumonisin concentration decreased (linear, p < 0.001) average daily gain, average daily feed intake (linear, p = 0.055), and gain:feed ratio (linear, p = 0.016). Although these response criteria tested linear, the greatest reduction in performance was in pigs fed with 32.7 and 35.1 mg/kg of fumonisin (B1 + B2). Increasing fumonisin concentration increased the serum SA:SO ratio (linear, p < 0.001) on day 14 and 28. In summary, for 9 to 28 kg nursery pigs, increasing fumonisin linearly decreased average daily gain and gain:feed ratio. However, despite the linear response, diets containing up to 21.9 mg/kg of fumonisin did not have as dramatic a decrease in growth performance as those fed more than 32.7 mg/kg. Further research is warranted to determine the effect of fumonisin concentrations between 21.9 and 32.7 mg/kg.

515 Late-Breaking: Effects of Dietary Phytase with or without Multi-carbohydrase Supplementation on Growth Performance, Nutrient Digestibility, and Bone Traits in Nursery Pigs

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 207-208
Author(s):  
Olumide E Adeshakin ◽  
Bonjin Koo ◽  
Robert Patterson ◽  
Martin Nyachoti
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Block Design ◽  
Average Daily Gain ◽  
Metacarpal Bone ◽  
Nutrient Digestibility ◽  
Experimental Unit ◽  
Deficient Diet ◽  
Nursery Pigs ◽  
Metacarpal Bones

Abstract The aim was to determine the effects of supplementing increasing doses of phytase (PHY) alone or in combination with multi-carbohydrase (MC) blend to a P-deficient diet for nursery pigs on growth performance, nutrient digestibility, and metacarpal bone characteristics. A total of 192 weaned pigs (7.7 ± 0.05 kg BW) were allotted to 1 of 8 dietary treatments each with 8 replicates in a randomised complete block design based on initial body weight. Diets consisted of a P-deficient negative control (NC), NC + 250 FTU/kg (TRT1), NC + 500 FTU/kg (TRT2), NC + 1,000 FTU/kg (TRT3), NC + 0.2g/kg MC (TRT4), TRT4 + 250 FTU/kg (TRT5), TRT4 + 500 FTU/kg (TRT6), and TRT4 + 1,000 FTU/kg (TRT7). Fecal samples (d 18, 19, and 20) and metacarpal bones (d21) were collected to determine apparent total tract digestibility (ATTD) of energy and nutrients and bone mineralization, respectively. Data were analyzed using the MIXED procedure of SAS with orthogonal polynomial contrast statements with a pen as an experimental unit for growth performance and digestibility and 1 pig per pen for bone traits. During week 2, MC supplementation tended to increase (P = 0.05) body weight whereas by week 3, increasing doses of PHY linearly (P &lt; 0.05) increased average daily gain (ADG). Overall, PHY supplementation had a quadratic effect (P &lt; 0.05) increasing ADG. However, there was an interaction (P &lt; 0.05) whereby PHY and MC in combination acted synergistically to increase percentage of ash and P ATTD. Phytase had linear (P &lt; 0.05) and quadratic (P &lt; 0.05) by increasing fat-free dry weight, ash content, and P in metacarpal bone. In conclusion, increasing levels of PHY quadratically improved growth performance, nutrient digestibility, and bone traits of pigs fed a P-deficient diet.

Effects of different concentrations of ground oak acorn on growth performance, blood parameters and carcass characteristics of goat kids

2015 ◽  
Vol 55 (1) ◽  
pp. 87 ◽  
Author(s):  
E. Froutan ◽  
O. Azizi ◽  
G. Sadeghi ◽  
F. Fatehi ◽  
S. Lashkari
Keyword(s):  
Growth Performance ◽  
Average Daily Gain ◽  
Carcass Characteristics ◽  
Blood Parameters ◽  
Abdominal Fat ◽  
Conversion Ratio ◽  
Feed Conversion ◽  
Low Concentrations ◽  
Daily Gain ◽  
Different Levels

The objective of the present study was to evaluate the effect of different levels of ground oak acorn on growth performance, blood parameters and carcass characteristics. Twenty-four goat kids averaging 16.93 ± 1.25 kg initial bodyweight were randomly assigned to four experimental diets in a completely randomised design for 90 days. The experimental diets consisted of (1) 0% oak acorn (control), (2) 8% oak acorn, (3) 17% oak acorn and (4) 25% oak acorn on a DM basis. The goats were slaughtered after 105 days of feeding and carcass characteristics were measured. DM intake increased linearly in small amounts as the level of acorn in the diet increased (P < 0.004). The results showed that average daily gain, water intake and feed conversion ratio were unaffected by levels of ground oak acorn (P > 0.05). There were no significant differences in blood parameters (P > 0.05). Carcass fat depth and abdominal fat weight decreased with increasing ground oak acorn in the diet. Other carcass characteristics were not affected by different levels of ground oak acorn. On the basis of the results of the present study, it may be concluded that ground oak acorn can be used up to 25% in the diets of young goats without any adverse effects on growth performance and carcass characteristics. At this level of acorns, the goats received low concentrations of hydrolysable tannins (11 g/kg DM) in their diet.

scholarly journals 88 Dietary supplementation of branched-chain amino acids higher than recommended levels in nursery pigs fed with moderately low protein diet: effects on growth performance

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 82-82
Author(s):  
Mohammad Habibi ◽  
Cedrick N Shili ◽  
Julia Sutton ◽  
Adel Pezeshki
Keyword(s):  
Amino Acids ◽  
Body Weight ◽  
Growth Performance ◽  
Feed Intake ◽  
Average Daily Gain ◽  
Branched Chain Amino Acids ◽  
Nursery Pigs ◽  
Low Protein ◽  
Branched Chain ◽  
Daily Gain

Abstract Feed cost and excess nutrients excretion are threatening the swine industry. Moderately low protein (MLP) diets are less expensive and reduce the nitrogen excretion, but they may have negative influence on growth performance of pigs. The aim of current study was to investigate the effect of MLP diets supplemented with branched-chain amino acids (BCAA; leucine, isoleucine and valine) higher than Nutrients Requirements of Swine (NRC) recommendation on the growth performance of nursery pigs. Forty-eight weaned barrows at 3 weeks of age were weighed, individually housed and randomly assigned to 6 dietary treatments including: 1) PCON: 20% crude protein (CP), 2) NCON: 14% CP; 3) C25: NCON+ limiting amino acids (LAA, i.e. lysine, methionine, threonine, and tryptophan) 25% more than NRC levels, 4) C50: NCON+LAA 50% higher than NRC recommendations; 5) CB25: NCON + (LAA+BCAA) 25% more than NRC; 6) CB50: NCON + (LAA+BCAA) 50% higher than NRC. The data were analyzed with univariate GLM with Tukey’s post-hoc test (SPSS®). The CB50 had higher final body weight, average daily gain, average daily water intake and average daily feed intake than C50 with the latter tended to be higher than NCON. Average daily feed intake, average daily gain and gain to feed ratio tended to be greater for CB25 and CB50 relative to C25 and C50, respectively. Compared to C50, CB50 improved the mean and cumulative feed intake in all the weeks. CB50 also tended to improve the body weight gain and gain: feed in week 2 relative to C50. In conclusion, supplementing MLP diets with limiting amino acid at 25% or 50% higher than NRC recommendations was failed to recover the negative effects of these diets on growth performance. Adding BCAA more than NRC levels to MLP diets improved the growth performance with the effects of added BCAA level being negligible.

scholarly journals Evaluation of the effect of β-mannanase supplementation and mannans on nursery pig growth performance and serum acute-phase protein concentrations

2020 ◽  
Vol 100 (1) ◽  
pp. 111-118
Author(s):  
Nichole F. Huntley ◽  
Stacie A. Gould ◽  
John F. Patience
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Acute Phase ◽  
Acute Phase Proteins ◽  
Average Daily Gain ◽  
Innate Immune ◽  
Nursery Pigs ◽  
Reactive Protein ◽  
Nursery Pig ◽  
Daily Gain

The objective was to evaluate the effects of dietary mannan and β-mannanase supplementation on growth performance and serum acute-phase proteins in nursery pigs. Pigs (n = 480) were blocked by initial body weight (6.6 ± 0.4 kg), and 12 pens per treatment were randomly assigned to one of four treatments in a 2 × 2 factorial arrangement for 28 d. Two levels of dietary mannan (0.4% vs. 2.8%) were offered with and without 0.05% endo-1,4-β-mannanase. Serum was collected (one pig per pen) for haptoglobin and C-reactive protein (CRP) analysis on days 0 and 28. There were no significant interactions between mannan level and β-mannanase supplementation. High-mannan diet decreased average daily gain (P = 0.027) and average daily feed intake (P = 0.024) compared with low-mannan diets with no effect of β-mannanase (P > 0.10). Haptoglobin and CRP were not affected by mannan level or β-mannanase supplementation (P ≥ 0.160). Therefore, dietary β-mannans as high as 2.8% did not induce a systemic innate immune response. Thus, the levels of β-mannan found in practical diets (<2%) are unlikely to induce an immune response; therefore, supplementation of β-mannanase to avoid this response is not warranted.

scholarly journals THE EFFECT OF RUMEN UNDEGRADABLE PROTEIN LEVEL OF CONCENTRATE WITH RICE STRAW AS BASAL DIET ON GROWTH PERFORMANCE OF SUMBA ONGOLE BEEF CATTLE

2017 ◽  
Vol 41 (2) ◽  
pp. 142
Author(s):  
Ainin Fauzyah ◽  
Panjono Panjono ◽  
Ali Agus ◽  
I Gede Suparta Budisatria ◽  
Budi Prasetyo Widyobroto
Keyword(s):  
Growth Performance ◽  
Rice Straw ◽  
Nutrient Intake ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Feed Conversion ◽  
Random Group ◽  
Rumen Undegradable Protein ◽  
Daily Gain ◽  
Different Levels

This research was conducted to determine growth performance of SO beef catlle fed rice straw added with concentrate with different levels of RUP, RUP used was soybean meal protected with 0.8% formaldehyde. Thirty six SO bull were divided into two groups at random, group that fed low and high RUP. Feed in the form of rice straw and concentrate with a ratio of 30:70 in dry matter (DM). Cattle fed low RUP get concentrate containing DM 91.22%, crude protein (CP) 19.38%, RUP 33.05%, and TDN 51.71%, whereas cattle fed high RUP get a concentrate with DM 91.13%, CP 19.40%, RUP 41.13%, and TDN 51.57%. Water was given unlimited. The nutrient intake and growth performance parameters analyzed using independent sample t-test, average daily gain was analyzed by ANCOVA with initial body weight as covariates. Intake RDP and RUP had significant effect (P<0.05) between cattle fed low and high RUP. Nutrient intake (DM, CP, TDN) and growth performance (average daily gain (ADG), feed conversion, feed cost per gain) showed not significant between cattle fed low and high RUP. The conclusion were the increased of RUP levels could improved growth performance of SO beff cattle.

scholarly journals PSVI-1 Dietary protease supplementation on growth performance and post-weaning diarrhea of nursery pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 191-192
Author(s):  
Jorge Y Perez-Palencia ◽  
David A Clizer ◽  
Christian Ramirez-Camba ◽  
Ryan S Samuel ◽  
Crystal L Levesque
Keyword(s):  
Growth Performance ◽  
Phase 1 ◽  
Dietary Treatment ◽  
Experimental Period ◽  
Phase 2 ◽  
Deficient Diet ◽  
Nursery Pigs ◽  
Feeding Program ◽  
Dietary Treatments ◽  
Fecal Score

Abstract This experiment evaluated the effect of dietary protease supplementation on pig’s growth performance and post-weaning diarrhea in a 43-d trial. A total of 936 weaned pigs [21 d of age, initial BW 5.87 ± 0.31 kg] were used in a 2 × 2 factorial design (2 nutritional levels × 2 protease levels). The nutritional levels corresponded to a standard feeding program and a reduced feeding program (15% lower SID Lys) and without or with protease supplementation (0.0125% inclusion). Piglets were distributed in 36 pens with 26 pigs per pen and 9 replicates per dietary treatment. Pigs received a common Phase 1 diet and experimental diets in Phase 2, 3, and 4, (0.91, 3.4, 4.5, and 24.0 kg/pig, respectively). Phytase was included at 2,500 U in Phase 2 – 4, all diets met energy and AA:Lys requirements for nursery pigs. Feed intake and body weight were determined every 2 weeks. A pen fecal score assessment was performed at d7, 10, and 14. Performance data were analyzed using the PROC MIXED procedure and fecal score data using the PROC FREQ procedure (SAS Inst., Inc., Cary, NC). No significant interactions (P &gt; 0.05) were observed between dietary treatments. From d15 to 43 and during overall experimental period, pigs fed standard diets had greater BW, ADG, and G:F (P &lt; 0.05) than pigs fed deficient diets (Table 1). On d7, pigs fed deficient diet had more (X2 &lt; 0.05) soft and watery feces, and consequently less normal feces compared to pigs fed standard diets (Figure 1). On d7, 10, and 14, pigs fed diets with protease supplementation had more (X2 &lt; 0.05) normal feces compared to control pigs. Overall, effects of dietary protease supplementation on growth performance were not expressive under the conditions of this study but protease addition benefited intestinal health of nursery pigs.

PSVI-14 Blend of Additives in Nursery Pig Diets as an Antibiotics Substitute Increases the Growth Performance and Intestinal Health

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 201-201
Author(s):  
Sudario Roberto Silva Junior ◽  
Rhuan F Chaves ◽  
Maíra Resende ◽  
Ygor Henrique De Paula ◽  
Kenio De Gouvêa Cabral ◽  
...  
Keyword(s):  
Growth Performance ◽  
Animal Feed ◽  
Block Design ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Intestinal Health ◽  
Total Period ◽  
Nursery Pigs ◽  
Randomized Block Design ◽  
Diarrhea Incidence

Abstract Antibiotics growth promoting (AGP) in animal feed has been restricted. With this, several additives have been tested in order to replace AGP and ensure intestinal health. The objective of this study was to evaluate the effects of a blend of additives on growth performance, diarrhea incidence and cecal content microbiota of nursery pigs. A total of 576 weaned pigs (6.21 ± 1.16 kg) were assigned into 4 treatments (12 replicates) in randomized block design: basal diet without additives (NC); basal diet with 120 ppm of halquinol (PC); NC + 0,05% blend of lactic acid (3,5%), benzoic acid (2,5%), flavonoids (3,5%) (B5); NC+ 0,1% of same blend (B10). The pigs were weighed 0 and 42 days into the experiment. On day 10, one animal per pen (10 replicates) was euthanized for microbiota analyses. The diarrhea incidence was calculated by the percentage of visual pens with diarrhea, by day, in the period. The growth performance was analyzed by GLIMMIX procedure and the means were compared with Tukey test (P &lt; 0.050) (SAS, 2009). Diarrhea incidence was analyzed by GENMOD procedure (SAS, 2009). The Kruskal Wallis test was used to compare microbial biodiversity (P &lt; 0.050) by statistical program STAMP. The final weight (P = 0.010) and average daily gain (P = 0.001) of B10 and PC were higher than NC. Regarding diarrhea, it was observed that the B5 and B10 had lower incidence when compared to other groups in the total period. In the microbiome analyses, it was observed that the B5, B10, and PC groups had lower (P = 0.021) biodiversity when compared to the NC piglets. However, the B5 and B10 group had higher biodiversity when compared to the PC group. In conclusion, the supplementation with 0,1% blend of additives can be a substitute for AGP.

scholarly journals Live Yeast or Live Yeast Combined with Zinc Oxide Enhanced Growth Performance, Antioxidative Capacity, Immunoglobulins and Gut Health in Nursery Pigs

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1626
Author(s):  
Shenfei Long ◽  
Tengfei He ◽  
Sung Woo Kim ◽  
Qinghui Shang ◽  
Tadele Kiros ◽  
...  
Keyword(s):  
Average Daily Gain ◽  
Basal Diet ◽  
Conversion Ratio ◽  
Gut Health ◽  
Total Volatile ◽  
Feed Conversion ◽  
Nursery Pigs ◽  
Serum Iga ◽  
Daily Gain ◽  
Live Yeast

This study aimed to investigate the effects of dietary LY or LY combined with ZnO supplementation on performance and gut health in nursery pigs. 192 Duroc × Landrace × Yorkshire piglets (weaned on d 32 of the age with 9.2 ± 1.7 kg BW) were allocated into four treatments with eight replicate pens, six piglets per pen. The treatments included a basal diet as control (CTR), an antibiotic plus ZnO diet (CTC-ZnO, basal diet + 75 mg/kg of chlortetracycline + ZnO (2000 mg/kg from d 1 to 14, 160 mg/kg from d 15 to 28)), a LY diet (LY, basal diet + 2 g/kg LY), and a LY plus ZnO diet (LY-ZnO, basal diet + 1 g/kg LY + ZnO). The results showed that pigs fed LY or LY-ZnO had increased (p < 0.05) average daily gain, serum IgA, IgG, superoxide dismutase, fecal butyric acid, and total volatile fatty acid concentrations, as well as decreased (p < 0.05) feed conversion ratio and diarrhea rate compared with CTR. In conclusion, pigs fed diets with LY or LY combined with ZnO had similar improvement to the use of antibiotics and ZnO in performance, antioxidant status, immunoglobulins, and gut health in nursery pigs.

Sign in / Sign up

Export Citation Format

Share Document