scholarly journals Ten Open Questions about Laser-Induced Periodic Surface Structures

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3326
Author(s):  
Jörn Bonse ◽  
Stephan Gräf
Keyword(s):  
Industrial Applications ◽  
Surface Structures ◽  
Theoretical Modelling ◽  
Periodic Surface ◽  
Long Term Stability ◽  
Energy Technologies ◽  
Current State ◽  
Open Questions ◽  
Technological Limitations

Laser-induced periodic surface structures (LIPSS) are a simple and robust route for the nanostructuring of solids that can create various surface functionalities featuring applications in optics, medicine, tribology, energy technologies, etc. While the current laser technologies already allow surface processing rates at the level of m2/min, industrial applications of LIPSS are sometimes hampered by the complex interplay between the nanoscale surface topography and the specific surface chemistry, as well as by limitations in controlling the processing of LIPSS and in the long-term stability of the created surface functions. This Perspective article aims to identify some open questions about LIPSS, discusses the pending technological limitations, and sketches the current state of theoretical modelling. Hereby, we intend to stimulate further research and developments in the field of LIPSS for overcoming these limitations and for supporting the transfer of the LIPSS technology into industry.

scholarly journals Enzyme-Functionalized Piezoresistive Hydrogel Biosensors for the Detection of Urea

Sensors ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2858 ◽  
Author(s):  
Jan Erfkamp ◽  
Margarita Guenther ◽  
Gerald Gerlach
Keyword(s):  
Swelling Pressure ◽  
Industrial Applications ◽  
Similar Species ◽  
Ph Change ◽  
Important Indicator ◽  
Long Term Stability ◽  
Piezoresistive Pressure Sensor ◽  
Biomedical Diagnostics ◽  
Hydrogel System

Urea is used in a wide variety of industrial applications such as the production of fertilizers. Furthermore, urea as a metabolic product is an important indicator in biomedical diagnostics. For these applications, reliable urea sensors are essential. In this work, we present a novel hydrogel-based biosensor for the detection of urea. The hydrolysis of urea by the enzyme urease leads to an alkaline pH change, which is detected with a pH-sensitive poly(acrylic acid-co-dimethylaminoethyl methacrylate) hydrogel. For this purpose, the enzyme is physically entrapped during polymerization. This enzyme-hydrogel system shows a large sensitivity in the range from 1 mmol/L up to 20 mmol/L urea with a high long-term stability over at least eight weeks. Furthermore, this urea-sensitive hydrogel is highly selective to urea in comparison to similar species like thiourea or N-methylurea. For sensory applications, the swelling pressure of this hydrogel system is transformed via a piezoresistive pressure sensor into a measurable output voltage. In this way, the basic principle of hydrogel-based piezoresistive urea biosensors was demonstrated.

Promises and challenges of perovskite solar cells

Science ◽  
2017 ◽  
Vol 358 (6364) ◽  
pp. 739-744 ◽  
Author(s):  
Juan-Pablo Correa-Baena ◽  
Michael Saliba ◽  
Tonio Buonassisi ◽  
Michael Grätzel ◽  
Antonio Abate ◽  
...  
Keyword(s):  
Solar Cells ◽  
Performance Metrics ◽  
Perovskite Solar Cells ◽  
Open Circuit ◽  
Carrier Lifetimes ◽  
Long Term Stability ◽  
Current State ◽  
Recent Developments ◽  
Key Issues

The efficiencies of perovskite solar cells have gone from single digits to a certified 22.1% in a few years’ time. At this stage of their development, the key issues concern how to achieve further improvements in efficiency and long-term stability. We review recent developments in the quest to improve the current state of the art. Because photocurrents are near the theoretical maximum, our focus is on efforts to increase open-circuit voltage by means of improving charge-selective contacts and charge carrier lifetimes in perovskites via processes such as ion tailoring. The challenges associated with long-term perovskite solar cell device stability include the role of testing protocols, ionic movement affecting performance metrics over extended periods of time, and determination of the best ways to counteract degradation mechanisms.

High-frequency Oscillations in Epilepsy: What Have We Learned and What Needs to be Addressed

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011465 ◽  
Author(s):  
Zhuying Chen ◽  
Matias I. Maturana ◽  
Anthony N. Burkitt ◽  
Mark J. Cook ◽  
David B. Grayden
Keyword(s):  
High Frequency ◽  
Future Research ◽  
Great Promise ◽  
Clinical Biomarkers ◽  
High Frequency Oscillations ◽  
Visual Identification ◽  
Current State ◽  
Open Questions ◽  
Term Data

For the past two decades, high-frequency oscillations (HFOs) have been enthusiastically studied by the epilepsy community. Emerging evidence shows that HFOs harbour great promise to delineate epileptogenic brain areas and possibly predict the likelihood of seizures. Investigations into HFOs in clinical epilepsy have advanced from small retrospective studies relying on visual identification and correlation analysis to larger prospective assessments using automatic detection and prediction strategies. While most studies have yielded promising results, some have revealed significant obstacles to clinical application of HFOs, thus raising debate about the reliability and practicality of HFOs as clinical biomarkers. In this review, we give an overview of the current state of HFO research and pinpoint the conceptual and methodological issues that have hampered HFO translation. We highlight recent insights gained from long-term data, high-density recordings and multicentre collaborations, and discuss the open questions that need to be addressed in future research.

scholarly journals Effects of Ionic Liquids on Metalloproteins

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 514
Author(s):  
Aashka Y. Patel ◽  
Keertana S. Jonnalagadda ◽  
Nicholas Paradis ◽  
Timothy D. Vaden ◽  
Chun Wu ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Rapid Development ◽  
Industrial Applications ◽  
Short Term ◽  
Long Term Stability ◽  
Therapeutic Delivery ◽  
Protein Molecules ◽  
Function Relationship ◽  
And Function

In the past decade, innovative protein therapies and bio-similar industries have grown rapidly. Additionally, ionic liquids (ILs) have been an area of great interest and rapid development in industrial processes over a similar timeline. Therefore, there is a pressing need to understand the structure and function of proteins in novel environments with ILs. Understanding the short-term and long-term stability of protein molecules in IL formulations will be key to using ILs for protein technologies. Similarly, ILs have been investigated as part of therapeutic delivery systems and implicated in numerous studies in which ILs impact the activity and/or stability of protein molecules. Notably, many of the proteins used in industrial applications are involved in redox chemistry, and thus often contain metal ions or metal-associated cofactors. In this review article, we focus on the current understanding of protein structure-function relationship in the presence of ILs, specifically focusing on the effect of ILs on metal containing proteins.

scholarly journals Quo Vadis LIPSS?—Recent and Future Trends on Laser-Induced Periodic Surface Structures

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1950 ◽  
Author(s):  
Jörn Bonse
Keyword(s):  
Research Area ◽  
Industrial Applications ◽  
Surface Structures ◽  
Future Directions ◽  
Periodic Surface ◽  
Horizon 2020 ◽  
Current Trends ◽  
Wide Range ◽  
One Step ◽  
Quo Vadis

Nanotechnology and lasers are among the most successful and active fields of research and technology that have boomed during the past two decades. Many improvements are based on the controlled manufacturing of nanostructures that enable tailored material functionalization for a wide range of industrial applications, electronics, medicine, etc., and have already found entry into our daily life. One appealing approach for manufacturing such nanostructures in a flexible, robust, rapid, and contactless one-step process is based on the generation of laser-induced periodic surface structures (LIPSS). This Perspective article analyzes the footprint of the research area of LIPSS on the basis of a detailed literature search, provides a brief overview on its current trends, describes the European funding strategies within the Horizon 2020 programme, and outlines promising future directions.

scholarly journals Environment-Induced Reversible Modulation of Optical and Electronic Properties of Lead Halide Perovskites and Possible Applications to Sensor Development: A Review

Molecules ◽  
2021 ◽  
Vol 26 (3) ◽  
pp. 705
Author(s):  
Maria Luisa De Giorgi ◽  
Stefania Milanese ◽  
Argyro Klini ◽  
Marco Anni
Keyword(s):  
Electronic Properties ◽  
Optical Sensors ◽  
State Of The Art ◽  
Active Materials ◽  
Long Term Stability ◽  
Current State ◽  
Optical And Electronic Properties ◽  
Halide Perovskites ◽  
Lead Halide

Lead halide perovskites are currently widely investigated as active materials in photonic and optoelectronic devices. While the lack of long term stability actually limits their application to commercial devices, several experiments demonstrated that beyond the irreversible variation of the material properties due to degradation, several possibilities exist to reversibly modulate the perovskite characteristics by acting on the environmental conditions. These results clear the way to possible applications of lead halide perovskites to resistive and optical sensors. In this review we will describe the current state of the art of the comprehension of the environmental effects on the optical and electronic properties of lead halide perovskites, and of the exploitation of these results for the development of perovskite-based sensors.

Stability and Change in Emotional Intelligence: Exploring the Transition to Young Adulthood

2005 ◽  
Vol 26 (2) ◽  
pp. 100-106 ◽  
Author(s):  
James D.A. Parker ◽  
Donald H. Saklofske ◽  
Laura M. Wood ◽  
Jennifer M. Eastabrook ◽  
Robyn N. Taylor
Keyword(s):  
High School ◽  
Emotional Intelligence ◽  
Postsecondary Education ◽  
Life Transition ◽  
Full Time ◽  
Major Life ◽  
Long Term Stability ◽  
Time Period ◽  
Transition From High School

Abstract. The concept of emotional intelligence (EI) has attracted growing interest from researchers working in various fields. The present study examined the long-term stability (32 months) of EI-related abilities over the course of a major life transition (the transition from high school to university). During the first week of full-time study, a large group of undergraduates completed the EQ-i:Short; 32 months later a random subset of these students (N = 238), who had started their postsecondary education within 24 months of graduating from high school, completed the measures for a second time. The study found EI scores to be relatively stable over the 32-month time period. EI scores were also found to be significantly higher at Time 2; the overall pattern of change in EI-levels was more than can be attributed to the increased age of the participants.

Multi-Center Calibration of the Second Reference Material for Thromboplastin, Rabbit, Plain, Coded CRM 149R

1991 ◽  
Vol 65 (03) ◽  
pp. 263-267 ◽  
Author(s):  
A M H P van den Besselaar ◽  
R M Bertina
Keyword(s):  
Reference Material ◽  
Standard Error ◽  
Standard Errors ◽  
Sensitivity Index ◽  
Long Term Stability ◽  
Significant Bias ◽  
The Mean ◽  
The Relationship ◽  
International Sensitivity Index

SummaryIn a collaborative trial of eleven laboratories which was performed mainly within the framework of the European Community Bureau of Reference (BCR), a second reference material for thromboplastin, rabbit, plain, was calibrated against its predecessor RBT/79. This second reference material (coded CRM 149R) has a mean International Sensitivity Index (ISI) of 1.343 with a standard error of the mean of 0.035. The standard error of the ISI was determined by combination of the standard errors of the ISI of RBT/79 and the slope of the calibration line in this trial.The BCR reference material for thromboplastin, human, plain (coded BCT/099) was also included in this trial for assessment of the long-term stability of the relationship with RBT/79. The results indicated that this relationship has not changed over a period of 8 years. The interlaboratory variation of the slope of the relationship between CRM 149R and RBT/79 was significantly lower than the variation of the slope of the relationship between BCT/099 and RBT/79. In addition to the manual technique, a semi-automatic coagulometer according to Schnitger & Gross was used to determine prothrombin times with CRM 149R. The mean ISI of CRM 149R was not affected by replacement of the manual technique by this particular coagulometer.Two lyophilized plasmas were included in this trial. The mean slope of relationship between RBT/79 and CRM 149R based on the two lyophilized plasmas was the same as the corresponding slope based on fresh plasmas. Tlowever, the mean slope of relationship between RBT/79 and BCT/099 based on the two lyophilized plasmas was 4.9% higher than the mean slope based on fresh plasmas. Thus, the use of these lyophilized plasmas induced a small but significant bias in the slope of relationship between these thromboplastins of different species.

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