scholarly journals Vitamin B6 Status among Vegetarians: Findings from a Population-Based Survey

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1627
Author(s):  
Paula Schorgg ◽  
Till Bärnighausen ◽  
Sabine Rohrmann ◽  
Aedin Cassidy ◽  
Nena Karavasiloglou ◽  
...  
Keyword(s):  
Vitamin B6 ◽  
High Performance ◽  
Geometric Mean ◽  
Population Based ◽  
Vegetarian Diet ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Linear Regression Models ◽  
Vitamin B6 Deficiency ◽  
Objectively Measured

Vitamin B6 from plant foods may have lower bioavailability than vitamin B6 from animal foods, but studies on objectively measured vitamin B6 status among vegetarians compared to non-vegetarians are lacking. Thus, the vitamin B6 status among vegetarians, but also pescatarians, and flexitarians, compared to meat-eaters was assessed in the population-based NHANES study (cycles 2007–2008 and 2009–2010). Data on serum pyridoxal-5′-phosphate (PLP) and 4-pyridoxic acid (4-PA) measured by high-performance liquid chromatography (HPLC) as well as dietary intakes from 24-h recalls were available for 8968 adults aged 20–80 years. Geometric mean (±standard error) PLP concentrations were 58.2 ± 6.0, 52.1 ± 3.7, 49.2 ± 4.6 and 51.0 ± 1.1 nmol/L among vegetarians, pescatarians, flexitarians, and meat-eaters. The 4-PA concentrations were 32.7 ± 4.0, 29.0 ± 2.5, 34.8 ± 5.6 and 33.0 ± 0.7, respectively. There were no statistically significant differences in PLP, 4-PA, and their ratio across the groups in multivariable linear regression models. Overall, the use of vitamin B6 supplements was the strongest predictor of the vitamin B6 status, followed by the dietary vitamin B6 intake. Interestingly, several other covariates were significantly associated with vitamin B6 biomarker levels, particularly serum albumin, creatinine and alkaline phosphatase, and should be considered when assessing the vitamin B6 status. In summary, our findings suggest that a vegetarian diet does not pose a risk for vitamin B6 deficiency.

scholarly journals Dietary Vitamin B6 Deficiency Impairs Gut Microbiota and Host and Microbial Metabolites in Rats

Biomedicines ◽  
2020 ◽  
Vol 8 (11) ◽  
pp. 469
Author(s):  
Shyamchand Mayengbam ◽  
Faye Chleilat ◽  
Raylene A. Reimer
Keyword(s):  
Gut Microbiota ◽  
Vitamin B6 ◽  
Dietary Vitamin ◽  
Enzymatic Reactions ◽  
Sprague Dawley ◽  
Microbial Composition ◽  
Metabolic Markers ◽  
Vitamin B6 Deficiency ◽  
The Difference ◽  
The Impact

Vitamin B6 plays a crucial role as a cofactor in various enzymatic reactions but bacteria-produced vitamin B6 is not sufficient to meet host requirements. Our objective was to assess the impact of diet-derived vitamin B6 on gut microbiota and host serum metabolomics. Sprague–Dawley rats (n = 47) were fed a control, low B6 (LB6) or high B6 (HB6) diet for six weeks. Serum and cecal samples were collected for biochemical, metabolomics and gut microbiota profiling. There was a significant sex effect for gut microbiota and several metabolic markers. Bodyweight and percent body fat were significantly reduced in LB6 compared to control and HB6 rats. Microbial beta-diversity differed significantly between LB6 and the control and HB6 rats in both sexes. Lachnospiraceae_NK4A136_group and Bacteroides were the primary taxa driving the difference between LB6 and control. There was a significant separation of cecal and serum metabolites of LB6 compared to control and HB6 rats. In the cecum, arginine biosynthesis was impaired, while vitamin B6 metabolism, lysine degradation and nicotinate and nicotinamide metabolism were impaired in serum metabolite profiles. Cecal propionate and butyrate were significantly reduced in LB6 rats irrespective of sex. Host vitamin B6 deficiency but not excess significantly alters gut microbial composition and its metabolites.

Vitamin B6 During Pregnancy

1982 ◽  
Vol 1 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Barbara Pickard
Keyword(s):  
Oral Contraceptive ◽  
Vitamin B6 ◽  
Hormonal Changes ◽  
Dietary Intakes ◽  
Contributing Factors ◽  
Maternal Vitamin ◽  
Contraceptive Usage ◽  
Synthetic Vitamin ◽  
Daily Diet ◽  
Vitamin B6 Deficiency

A vitamin B6 deficiency develops during pregnancy and contributing factors include: a disturbance in vitamin B6 metabolism caused by increasing levels of oestrogens; increasing fetal demand for vitamin B6; a disturbance in vitamin B6 status caused by oral contraceptive usage prior to conception; a deficient intake of vitamin B6. Hormonal changes and increasing fetal requirements impose considerable stress on maternal vitamin B6 status but are the inevitable consequences of pregnancy. In contrast, longterm use of oral contraceptives before pregnancy and an inadequate vitamin B6 intake, both prior to and during pregnancy, are potentially avoidable. Dietary intakes of vitamin B6 in many women fall well below the recommended 1.5–2.0mg/day before pregnancy and 2.5mg/day during pregnancy. Although supplementation with synthetic vitamin B6 is advocated by many, much greater emphasis should also be placed on a wholesome, healthy diet. Examples are given of foods high and low in vitamin B6 and of a daily diet providing 2.5mg of vitamin B6.

scholarly journals Urinary sodium to potassium ratio: A simple and useful indicator of diet quality in population-based studies

2019 ◽  
Author(s):  
Parvin Mirmiran ◽  
Zahra Gaeini ◽  
Zahra Bahadoran ◽  
Asghar Ghasemi ◽  
Norouzirad Reza ◽  
...  
Keyword(s):  
Diet Quality ◽  
Dietary Patterns ◽  
Dietary Pattern ◽  
Population Based ◽  
Urinary Sodium ◽  
Dash Score ◽  
Dietary Intakes ◽  
Linear Regression Models ◽  
Significant Positive Association ◽  
Spot Urine

Abstract Background Urinary sodium (Na) and potassium (K) are related to dietary intakes of Na and K, and well-known risk factors of hypertension and cardiovascular events. This study aimed to evaluate the associations between urinary Na/K ratio and different dietary patterns. Methods we recruited 1864 adult men and women (aged 18-93 years), participated in the sixth examination of Tehran Lipid and Glucose Study. Fasting spot urine samples were collected and concentrations of Na and K were determined. The principle component analysis (PCA) was conducted to drive major dietary patterns among population. Mediterranean dietary pattern score, as well as DASH score, were calculated. Linear regression models adjusted for potential confounding variables were used to assess associations between dietary patterns scores and urinary Na/K ratio. Results Mean age of participants was 43.7±13.9 years, and 47% were men. Mean urinary Na and K concentrations were 139±41.0 and 57.9±18.6 mmol/L, respectively. Mean urinary Na/K was 2.40±0.07. A significant positive association was found between Western dietary pattern and urinary Na/K ratio (β=0.06; 95% CI= 0.01, 0.16). Traditional dietary pattern derived from usual dietary intakes of Iranian adults, as well as Mediterranean and DASH dietary pattern scores were inversely associated to urinary Na/K ratio (β= –0.14; 95% CI= –0.24, –0.11, β=–0.07; 95% CI= –0.09, –0.01, β=–0.12; 95% CI= –0.05, –0.02, respectively). Conclusions Urinary Na/K ratio may suggest as a simple, inexpensive and helpful method to monitor and improve diet quality in population-based studies.

Liver-specific increase of UTP and UDP-sugar concentrations in rats induced by dietary vitamin B6-deficiency and its relation to complex N-glycan structures of liver membrane-proteins

2007 ◽  
Vol 24 (9) ◽  
pp. 531-541 ◽  
Author(s):  
Agnes B. Renner ◽  
Kathrin Rieger ◽  
Detlef Grunow ◽  
Martin Zimmermann-Kordmann ◽  
Martin Gohlke ◽  
...  
Keyword(s):  
Membrane Proteins ◽  
Vitamin B6 ◽  
Dietary Vitamin ◽  
Liver Membrane ◽  
Specific Increase ◽  
Vitamin B6 Deficiency

scholarly journals Association of Polyunsaturated Fatty Acids and Vitamin B6 with Inflammation in Adults from the National Health and Nutrition Examination Survey (NHANES) 2003–2004

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1816-1816
Author(s):  
Hyojung Kim ◽  
Evelyn Enrione ◽  
Vijaya Narayanan ◽  
Tan Li ◽  
Adriana Campa
Keyword(s):  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Vitamin B6 ◽  
Inflammatory Responses ◽  
Survey Design ◽  
Dietary Vitamin ◽  
Significance Level ◽  
Plasma Ratio ◽  
Vitamin B6 Deficiency ◽  
Pufa Metabolism

Abstract Objectives Polyunsaturated fatty acids (PUFA) such as n-3 PUFA, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and n-6 PUFA, arachidonic acid (AA) may mediate inflammatory responses. Vitamin B6 deficiency has been shown to alter plasma PUFA levels. This perturbation of PUFA metabolism in vitamin B6 deficiency measured by pyridoxal-5’-phosphate (PLP) may contribute to inflammation. Thus, we aimed to examine the associations of 1) dietary EPA + DHA, and vitamin B6 with plasma ratio of AA/(EPA + DHA) by PLP level, 2) plasma AA/(EPA + DHA) and PLP with C-reactive protein (CRP), a marker for inflammation, and 3) dietary EPA + DHA, and vitamin B6 with CRP level, using NHANES. Methods NHANES datasets (2003–2004) with subjects ≥20 years were analyzed, accounting for survey design and sample weights (n = 4486). The significance level was P < 0.05. Covariates were age, gender, ethnicity, BMI, smoking, alcohol, total energy, dietary supplements, physical activity, and NSAIDs, depending on analyses. Multiple linear regression assessed the association of dietary EPA + DHA, and vitamin B6 with plasma ratio of AA/(EPA + DHA) by PLP level (Low: < 20 nmol/L, High: ≥20 nmol/L). Next, multivariate logistic regression predicted the associations of plasma AA/(EPA + DHA) and PLP with CRP level (Low: ≤3 mg/L, Moderate to High: > 3 mg/L); then, dietary EPA + DHA, and B6 with CRP level. Results In the low PLP level, dietary EPA + DHA was negatively associated with plasma ratio of AA/(EPA + DHA) (B = ─5.29, SE = 0.84, P = < .0001), but B6 intake was not, whereas, in the high PLP level, both dietary EPA + DHA (B = ─2.99, SE = 0.53, P = < .0001) and dietary vitamin B6 (B = ─0.21, SE = 0.04, P = 0.0001) were inversely associated with plasma AA/(EPA + DHA). Further, low PLP level was associated with greater odds of moderate to high CRP level compared to high PLP level (adjusted OR (aOR): 2.8, 95% CI: 1.93–4.04, P = < .0001), but plasma AA/(EPA + DHA) was not. In addition, both dietary EPA + DHA (aOR: 0.5, 95% CI: 0.23–0.98, P = 0.04) and vitamin B6 (aOR: 0.8, 95% CI: 0.68–0.95, P = 0.009) were inversely associated with moderate to high CRP level. Conclusions Our findings show that low plasma PLP level and low vitamin B6 intake are associated with inflammation, and the relationship may be through their effect on PUFA metabolism, suggesting that increased intake of vitamin B6 and EPA and DHA may protect against inflammation. Funding Sources N/A.

Associations of dietary B vitamins intakes with depression in adults

2021 ◽  
Author(s):  
Yanjun Wu ◽  
Suyun Li ◽  
Weijing Wang ◽  
Dongfeng Zhang
Keyword(s):  
Vitamin B12 ◽  
Vitamin B6 ◽  
Vitamin B1 ◽  
B Vitamins ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Vitamin B2 ◽  
Logistic Regression Models ◽  
The People ◽  
The Impact

Abstract. Background: The impact of the dietary B vitamins intakes on the development of depression has been scarcely investigated. Thus, this study aimed to examine the associations of dietary B vitamins intakes with the risk of depression in American adults. Methods: The data we used in this study were from the National Health and Nutrition Examination Survey (NHANES) 2007-2014. We used the Logistic regression models to analyze the associations of the dietary intakes of B vitamins with the risk of depression. Results: 17,732 individuals (8,623 males and 9,109 females) were enrolled in the study and they were all 18 or older. Compared to the lowest quartile of dietary intake, the ORs (95%CIs) of the highest quartile were 0.64 (0.50–0.82), 0.78 (0.62–0.97), 0.60 (0.47–0.78), 0.65 (0.50–0.84), and 0.71 (0.54–0.95) for vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12, respectively. Compared to the people whose dietary intakes below the RDA in the model 2, those with intake meeting the RDA of vitamin B1 (OR: 0.68; 95%CI: 0.56–0.84), niacin (OR: 0.65; 95%CI: 0.51–0.81), B6 (OR: 0.65; 95%CI: 0.52–0.81), or B12 (OR: 0.65; 95%CI: 0.48–0.88) had a lower risk of depression, severally. We also found a nonlinear negative association between dietary vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12 intakes and the risk of depression in the dose-response analyses, severally. Conclusions: Our results suggested that dietary vitamin B1, vitamin B2, niacin, vitamin B6, and vitamin B12 intakes may be inversely associated with the risk of depression.

Vitamin B6 and Exercise

1994 ◽  
Vol 4 (2) ◽  
pp. 89-103 ◽  
Author(s):  
Melinda M. Manore
Keyword(s):  
Growth Hormone ◽  
Vitamin B6 ◽  
Low Energy ◽  
Dietary Vitamin ◽  
Dietary Intakes ◽  
Plasma Growth Hormone ◽  
Male Athletes

This paper presents an overview of vitaminand exercise, including the role that vitaminplays in gluconeogenesis and glycogenolysis and changes in vitaminmetabolism during exercise. The dietary vitaminintakes of athletes are also reviewed. Most studies report that male athletes have adequate dietary intakes of vitamin, whereas some females, especially those with low energy intakes, appear to have low vitaminintakes. Few studies have assessed the vitaminstatus of nonsupplementing athletes using the recommended status criteria. The role that vitaminmay play in attenuating the rise in plasma growth hormone observed during exercise is also reviewed. Finally, recomrnendations are given for further research in the area of vitaminand exercise.

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