scholarly journals Role of Phaseolus vulgaris L. in the Prevention of Cardiovascular Diseases—Cardioprotective Potential of Bioactive Compounds

Plants ◽  
2022 ◽  
Vol 11 (2) ◽  
pp. 186
Author(s):  
Lyanne Rodríguez ◽  
Diego Mendez ◽  
Hector Montecino ◽  
Basilio Carrasco ◽  
Barbara Arevalo ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Cardiovascular Events ◽  
Circulatory System ◽  
Developed Countries ◽  
Soluble Fiber ◽  
Phaseolus Vulgaris L ◽  
Mortality And Morbidity ◽  
Relevant Role

In terms of safe and healthy food, beans play a relevant role. This crop belongs to the species of Phaseolusvulgaris L., being the most consumed legume worldwide, both for poor and developed countries, the latter seek to direct their diet to healthy feeding, mainly low in fat. Phaseolus vulgaris L. stands out in this area—an important source of protein, vitamins, essential minerals, soluble fiber, starch, phytochemicals, and low in fat from foods. This species has been attributed many beneficial properties for health; it has effects on the circulatory system, immune system, digestive system, among others. It has been suggested that Phaseolus vulgaris L. has a relevant role in the prevention of cardiovascular events, the main cause of mortality and morbidity worldwide. Conversely, the decrease in the consumption of this legume has been related to an increase in the prevalence of cardiovascular diseases. This review will allow us to relate the nutritional level of this species with cardiovascular events, based on the correlation of the main bioactive compounds and their role as cardiovascular protectors, in addition to revealing the main mechanisms that explain the cardioprotective effects regulated by the bioactive components.

Bioactive Compounds of Black Bean (Phaseolus vulgaris L.)

2021 ◽  
pp. 623-641
Author(s):  
Balkisu O. Abdulrahman ◽  
Muntari Bala ◽  
Oluwasesan Micheal Bello
Keyword(s):  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Phaseolus Vulgaris L ◽  
Black Bean

scholarly journals Ten year cardio-cerebro-vascular mortality and morbidity in a Southern Italy cohort: the VIP Project data

2015 ◽  
Vol 80 (1) ◽  
Author(s):  
Vincenzo Capuano ◽  
Norman Lamaida ◽  
Sergio Torre ◽  
Ernesto Capuano ◽  
Maria Immacolata Borrelli ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular Events ◽  
Southern Italy ◽  
Geographical Area ◽  
Public Health Problem ◽  
Local Analysis ◽  
Mortality Data ◽  
Major Public Health Problem ◽  
Mortality And Morbidity ◽  
European Standard Population

Rationale: In Italy the mortality data were obtained almost exclusively from the data RENCAM (Name Causes of Death Register), while there are few prospective surveys. In order to assess whether there are particular epidemiological conditions in the geographical area of Mercato S. Severino, in Southern Italy, we have studied, and reassessed at ten years (1998/99 - 2008/09), a cohort of adult general population in a project of cardiovascular epidemiology and prevention. Materials and Methods: We calculated the rates of mortality and morbidity from cardiovascular events covering the period 1998/99 - 2008/09, in a cohort of 1200 persons (600 men and 600 women) aged 25 to 74 years. Data were standardized using the European standard population. Results: Mortality from cardiovascular causes was 46,5% in men and 48,7% in women; it was mainly concentrated in the age group 65-74 years where it occurred on 62,9% of deaths in men and 66,7% in women. Regarding morbidity, the incidence of events to ten years of non-fatal myocardial infarction was 2,2% in men and of 1,8% in women. PTCA interventions to ten year have been 3,3% in men and 3,4% in women, the interventions of aorto-coronary bypass have been 2,4% and 0,5% for men and women respectively. While all major cardiovascular events have been more frequent in men, in women there was a higher incidence of stroke (1,6% vs 0,9%). Conclusions: Although by comparison with other European countries Italy is among the countries considered at low-risk of coronary heart disease, in Campania cardiovascular diseases reach higher rates than the rest of the country. Our results are in line with the literature data and confirm that cardiovascular diseases are a major public health problem. Local analysis to propose means to provide useful information for planning prevention interventions targeted to their own territory.

Evaluation of Bioactive Compounds in Bean Oils (Phaseolus vulgaris L.), Perola and BRS Valente Varieties

2018 ◽  
Vol 14 (1) ◽  
pp. 40-46 ◽  
Author(s):  
Wellington Mamoro Umeda ◽  
Debora Maria Moreno Luzia ◽  
Neuza Jorge
Keyword(s):  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Phaseolus Vulgaris L

scholarly journals Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability

2021 ◽  
Vol 8 ◽  
Author(s):  
Xinyi Shen ◽  
Lihua Li ◽  
Zhen Sun ◽  
Guangyao Zang ◽  
Lili Zhang ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Cardiovascular Diseases ◽  
Atherosclerotic Plaque ◽  
Cardiovascular Events ◽  
Thrombus Formation ◽  
Modern Society ◽  
Short Chain Fatty Acids ◽  
Mortality And Morbidity ◽  
Causes Of Mortality ◽  
The Stability

Cardiovascular diseases (CVDs) are major causes of mortality and morbidity in the modern society. The rupture of atherosclerotic plaque can induce thrombus formation, which is the main cause of acute cardiovascular events. Recently, many studies have demonstrated that there are some relationships between microbiota and atherosclerosis. In this review, we will focus on the effect of the microbiota and the microbe-derived metabolites, including trimethylamine-N-oxide (TMAO), short-chain fatty acids (SCFAs), and lipopolysaccharide (LPS), on the stability of atherosclerotic plaque. Finally, we will conclude with some therapies based on the microbiota and its metabolites.

Effects of industrial canning on the proximate composition, bioactive compounds contents and nutritional profile of two Spanish common dry beans (Phaseolus vulgaris L.)

2015 ◽  
Vol 166 ◽  
pp. 68-75 ◽  
Author(s):  
Mercedes M. Pedrosa ◽  
Carmen Cuadrado ◽  
Carmen Burbano ◽  
Mercedes Muzquiz ◽  
Blanca Cabellos ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Proximate Composition ◽  
Dry Beans ◽  
Phaseolus Vulgaris L ◽  
Nutritional Profile

Potential role of bioactive compounds of Phaseolus vulgaris L. on lipid-lowering mechanisms

2015 ◽  
Vol 76 ◽  
pp. 92-104 ◽  
Author(s):  
Aurea K. Ramírez-Jiménez ◽  
Rosalía Reynoso-Camacho ◽  
M. Elizabeth Tejero ◽  
Fabiola León-Galván ◽  
Guadalupe Loarca-Piña
Keyword(s):  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Potential Role ◽  
Lipid Lowering ◽  
Phaseolus Vulgaris L

scholarly journals Antioxidant effect of a fermented powder of Lady Joy bean in primary rat hepatocytes

2015 ◽  
Vol 20 (1) ◽  
Author(s):  
Margherita La Marca ◽  
Laura Pucci ◽  
Roberto Bollini ◽  
Rossella Russo ◽  
Francesca Sparvoli ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Phaseolus Vulgaris ◽  
Bioactive Compounds ◽  
Primary Cultures ◽  
Rat Hepatocytes ◽  
Antioxidant Effect ◽  
Phaseolus Vulgaris L ◽  
Detoxifying Enzymes ◽  
Nrf2 Pathway ◽  
Beneficial Effects

AbstractThe role and beneficial effects of plant and food extracts against various diseases induced by oxidative stress have received much attention in recent years. Legumes are rich in bioactive compounds, and some studies suggest a correlation between their consumption and a reduced incidence of diseases. Primary cultures of rat hepatocytes were used to investigate whether and how an extract obtained from a fermented powder of bean named Lady Joy (Phaseolus vulgaris L.) is able to regulate antioxidant and detoxifying enzymes through the NRF2 pathway, inhibit NF-kB activation, and reduce H

Valutazioni economiche di atorvastatina in prevenzione secondaria: un aggiornamento

2011 ◽  
Vol 12 (2S) ◽  
pp. 41-52 ◽  
Author(s):  
Simona De Portu ◽  
Sabato Montella ◽  
Paolo Cortesi ◽  
Enrica Menditto ◽  
Simona Cammarota ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Cardiovascular Diseases ◽  
Secondary Prevention ◽  
Cardiovascular Events ◽  
Cost Effective ◽  
Economic Benefits ◽  
Therapeutic Interventions ◽  
Lipid Lowering ◽  
Control Groups ◽  
Mortality And Morbidity

Introduction: cardiovascular diseases are the most common reason of mortality and morbidity in the world, despite therapeutic interventions have improved patients’ prognosis in the last decades. Aggressive lipid lowering treatment with atorvastatin has demonstrated to be effective in preventing the occurrence of new cardiovascular events requiring hospitalizations, in patients previously affected by coronary syndromes. However, the increasing costs of managing cardiovascular diseases impose a careful analysis of the economic benefits of these therapies. Objective: to assess the economic sustainability of using atorvastatin for the secondary prevention of cardiovascular events. Material and Methods: we derived clinical information from five randomized, multicenter trials (AVERT, IDEAL, MIRACL, PROVE-IT, TNT) evaluating efficacy and tolerability of high dosage treatment with atorvastatin over control groups in different patient populations and for different follow up periods. A costeffectiveness analysis in the perspective of the NHS has been performed, under the hypothesis of the imminent price reduction of atorvastatin, due to the loss of exclusivity. Results: in trials AVERT, MIRACL, PROVE IT, the treatment with atorvastatin has demonstrated to reduce both cardiovascular events and overall healthcare direct costs, compared to the respective control groups. In trials IDEAL and TNT, the therapy with atorvastatin has resulted to be cost effective, with incremental cost-effectiveness ratio respectively of € 6,310 for avoided event (vs simvastatin 10 mg) and € 9,058 for CV disease free patient (vs atorvastatin 10 mg). Discussion: the present study represents an update of previous cost-effectiveness analyses, which have previously evaluated the economic consequences of using atorvastatin for the secondary prevention of cardiovascular events. The present analysis has proved the economic benefits deriving from the usage of atorvastatin, which is a dominant alternative in the AVERT, MIRACL and PROVE-IT clinical settings, and a cost effective option in the IDEAL and TNT study populations.

scholarly journals Biofortification potential in common bean (Phaseolus vulgaris L.): bioactive compounds, antioxidant capacity and physicochemical properties of 155 varieties grown in México

2021 ◽  
Vol 49 (1) ◽  
pp. 12123
Author(s):  
Alejandro PALACIO-MÁRQUEZ ◽  
Damaris OJEDA-BARRIOS ◽  
Jorge JIMÉNEZ-CASTRO ◽  
Pablo PRECIADO-RANGEL ◽  
Ofelia A. HERNÁNDEZ-RODRÍGUEZ ◽  
...  
Keyword(s):  
Phaseolus Vulgaris ◽  
Physicochemical Properties ◽  
Antioxidant Capacity ◽  
Common Bean ◽  
Bioactive Compounds ◽  
Research Work ◽  
Principal Component ◽  
Phaseolus Vulgaris L ◽  
Fiber Protein ◽  
Place Of Origin

Common bean has been classified as an almost perfect food due to its high content of fiber, protein and bioactive compounds and its high antioxidant capacity, which has been attributed to having prevent diabetes, oxidative stress, bowel inflammation and cardiovascular diseases. The objective of this research work was to characterize the physicochemical properties and bioactive compounds of 155 varieties of common bean (Phaseolus vulgaris L.) produced in Mexico with potential to be biofortified. The contents of protein, fiber, fat, carbohydrates and energy were analyzed by the methods established by the AOAC, in addition the antioxidant capacity (DPPH), the content of total phenols, flavonoids, anthocyanins and phytic acid were obtained. Cluster, correlation, and principal component analysis were conducted. A total of 14 outstanding varieties was identified, where four varieties stood out about phenol and flavonoid content. A second group comprised by 10 varieties had high protein and anthocyanin levels and showed the second highest content of phenols and flavonoids. The diversity of beans obtained in outstanding varieties provides options for biofortification programs based on the consumption or place of origin of each variety.

Sign in / Sign up

Export Citation Format

Share Document