scholarly journals Laser Transmission Welding of Semi-Crystalline Polymers and Their Composites: A Critical Review

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 675
Author(s):  
Foram Dave ◽  
Muhammad Mahmood Ali ◽  
Richard Sherlock ◽  
Asokan Kandasami ◽  
David Tormey
Keyword(s):  
Carbon Black ◽  
Absorptive Part ◽  
Scanning Speed ◽  
Nucleating Agent ◽  
Current Status ◽  
Weld Strength ◽  
Laser Source ◽  
Smart Manufacturing ◽  
Laser Transmission Welding ◽  
Wide Range

The present review provides an overview of the current status and future perspectives of one of the smart manufacturing techniques of Industry 4.0, laser transmission welding (LTW) of semi-crystalline (SC) polymers and their composites. It is one of the most versatile techniques used to join polymeric components with varying thickness and configuration using a laser source. This article focuses on various parameters and phenomena such as inter-diffusion and microstructural changes that occur due to the laser interaction with SC polymers (specifically polypropylene). The effect of carbon black (size, shape, structure, thermal conductivity, dispersion, distribution, etc.) in the laser absorptive part and nucleating agent in the laser transmissive part and its processing conditions impacting the weld strength is discussed in detail. Among the laser parameters, laser power, scanning speed and clamping pressure are considered to be the most critical. This review also highlights innovative ideas such as incorporating metal as an absorber in the laser absorptive part, hybrid carbon black, dual clamping device, and an increasing number of scans and patterns. Finally, there is presented an overview of the essential characterisation techniques that help to determine the weld quality. This review demonstrates that LTW has excellent potential in polymer joining applications and the challenges including the cost-effectiveness, innovative ideas to provide state-of-the-art design and fabrication of complex products in a wide range of applications. This work will be of keen interest to other researchers and practitioners who are involved in the welding of polymers.

scholarly journals Simulated Effect of Carbon Black on High Speed Laser Transmission Welding of Polypropylene With Low Line Energy

2021 ◽  
Vol 8 ◽  
Author(s):  
M. Mahmood Ali ◽  
Foram Dave ◽  
Richard Sherlock ◽  
Alistair Mcilhagger ◽  
David Tormey
Keyword(s):  
Carbon Black ◽  
High Speed ◽  
Laser Source ◽  
Beam Diameter ◽  
Line Energy ◽  
Laser Transmission Welding ◽  
Degradation Temperature ◽  
Weld Depth ◽  
Transient Thermal ◽  
The Impact

Laser welding is an important manufacturing tool for a wide variety of polymer products including consumer goods, automotive components and medical devices. The laser process parameters and polymer properties have a significant impact on weld quality. Due to higher heat density generated by the laser transmission welding (LTW) technique, defining a set of suitable parameters for LTW of thermoplastics and composites can be challenging. In this work the effect of carbon black along other control parameters has been investigated for high speed welding using a laser source of 980 nm wavelength with low line energy. In this work, the finite element method (FEM)-based software COMSOL Multiphysics is used to create a 3D transient thermal model for LTW of isotactic polypropylene (iPP) and its composites with carbon black (CB) of concentrations ranging from 0.5 wt% to 1.5 wt%. The design of experiments based on Box-Behnken design (BBD) is used to organize the simulation experiments and mathematical models are developed based on multiple curvilinear regression analysis on the simulation findings. Independent control variables include the laser power, welding speed, beam diameter, and carbon black content in the absorbent polymer. The maximum weld temperature, weld width, and weld depth within the transmissive and absorptive layers are considered as dependent response variables. Furthermore, sensitivity analysis is carried out to investigate the impact of carbon black along with other independent variables on the responses. The welding feasibility check was performed on the basis of melt and degradation temperature of the materials, and weld depths of transmissive and absorptive layers. It has been observed that the composites containing 0.5 wt% and 1 wt% of CB can be welded successfully with neat iPP. However, due to a degradation temperature problem, composites having a larger proportion of CB (>1 wt%) appear to be more difficult to weld.

Current Status and Future Perspective for Research on Medicinal Plants with Anticancerous Activity and Minimum Cytotoxic Value

2019 ◽  
Vol 20 (12) ◽  
pp. 1227-1243
Author(s):  
Hina Qamar ◽  
Sumbul Rehman ◽  
D.K. Chauhan
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Anticancer Agents ◽  
Drug Targets ◽  
Psidium Guajava ◽  
Current Status ◽  
Future Perspective ◽  
Wide Range

Cancer is the second leading cause of morbidity and mortality worldwide. Although chemotherapy and radiotherapy enhance the survival rate of cancerous patients but they have several acute toxic effects. Therefore, there is a need to search for new anticancer agents having better efficacy and lesser side effects. In this regard, herbal treatment is found to be a safe method for treating and preventing cancer. Here, an attempt has been made to screen some less explored medicinal plants like Ammania baccifera, Asclepias curassavica, Azadarichta indica, Butea monosperma, Croton tiglium, Hedera nepalensis, Jatropha curcas, Momordica charantia, Moringa oleifera, Psidium guajava, etc. having potent anticancer activity with minimum cytotoxic value (IC50 >3μM) and lesser or negligible toxicity. They are rich in active phytochemicals with a wide range of drug targets. In this study, these medicinal plants were evaluated for dose-dependent cytotoxicological studies via in vitro MTT assay and in vivo tumor models along with some more plants which are reported to have IC50 value in the range of 0.019-0.528 mg/ml. The findings indicate that these plants inhibit tumor growth by their antiproliferative, pro-apoptotic, anti-metastatic and anti-angiogenic molecular targets. They are widely used because of their easy availability, affordable price and having no or sometimes minimal side effects. This review provides a baseline for the discovery of anticancer drugs from medicinal plants having minimum cytotoxic value with minimal side effects and establishment of their analogues for the welfare of mankind.

scholarly journals Current status of vascular access in Japan—from Dialysis Access Symposium 2017

2019 ◽  
Vol 20 (1_suppl) ◽  
pp. 38-44
Author(s):  
Mizuya Fukasawa
Keyword(s):  
Vascular Access ◽  
Current Status ◽  
Good Survival ◽  
Chronic Glomerulonephritis ◽  
Dialysis Access ◽  
Dialysis Patients ◽  
Survival Prognosis ◽  
Access Methods ◽  
Number Of Patients ◽  
Wide Range

At the second Dialysis Access Symposium held in Nagoya, Japan, a proposal was made to investigate the differences in vascular access methods used in different countries. In this article, we describe the management of vascular access in Japan. The Japanese population is rapidly aging, and the proportion of elderly patients on dialysis is also increasing. There were 325,000 dialysis patients in Japan at the end of 2015, of whom 65.1% were aged 65 years or above. The number of patients with diabetic nephropathy or nephrosclerosis as the underlying condition is also increasing, whereas the number with chronic glomerulonephritis is steadily decreasing. The Japanese health insurance system enables patients to undergo medical treatment at almost no out-of-pocket cost. Percutaneous transluminal angioplasty suffers from a severe device lag compared with other countries, but although there are limitations on permitted devices, the use of those that have been authorized is covered by medical insurance. One important point that is unique to Japan is that vascular access is performed and managed by doctors involved in dialysis across a wide range of disciplines, including nephrologists, surgeons, and urologists. This may be one factor contributing to the good survival prognosis of Japanese dialysis patients.

scholarly journals MOCVD Grown HgCdTe Heterostructures for Medium Wave Infrared Detectors

Coatings ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 611
Author(s):  
Waldemar Gawron ◽  
Jan Sobieski ◽  
Tetiana Manyk ◽  
Małgorzata Kopytko ◽  
Paweł Madejczyk ◽  
...  
Keyword(s):  
Buffer Layer ◽  
Infrared Detectors ◽  
Lattice Mismatch ◽  
Layer Growth ◽  
Ex Situ ◽  
Current Status ◽  
Organic Chemical ◽  
Infrared Band ◽  
Donor And Acceptor ◽  
Wide Range

This paper presents the current status of medium-wave infrared (MWIR) detectors at the Military University of Technology’s Institute of Applied Physics and VIGO System S.A. The metal–organic chemical vapor deposition (MOCVD) technique is a very convenient tool for the deposition of HgCdTe epilayers, with a wide range of compositions, used for uncooled infrared detectors. Good compositional and thickness uniformity was achieved on epilayers grown on 2-in-diameter, low-cost (100) GaAs wafers. Most growth was performed on substrates, which were misoriented from (100) by between 2° and 4° in order to minimize growth defects. The large lattice mismatch between GaAs and HgCdTe required the usage of a CdTe buffer layer. The CdTe (111) B buffer layer growth was enforced by suitable nucleation procedure, based on (100) GaAs substrate annealing in a Te-rich atmosphere prior to the buffer deposition. Secondary-ion mass spectrometry (SIMS) showed that ethyl iodide (EI) and tris(dimethylamino)arsenic (TDMAAs) were stable donor and acceptor dopants, respectively. Fully doped (111) HgCdTe heterostructures were grown in order to investigate the devices’ performance in the 3–5 µm infrared band. The uniqueness of the presented technology manifests in a lack of the necessity of time-consuming and troublesome ex situ annealing.

scholarly journals Optical whispering-gallery mode barcodes for high-precision and wide-range temperature measurements

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Jie Liao ◽  
Lan Yang
Keyword(s):  
High Precision ◽  
Dynamic Range ◽  
Single Mode ◽  
Whispering Gallery Mode ◽  
Temperature Measurements ◽  
Laser Source ◽  
Multiple Modes ◽  
Whispering Gallery ◽  
Wide Range ◽  
Thermal Sensing

AbstractTemperature is one of the most fundamental physical properties to characterize various physical, chemical, and biological processes. Even a slight change in temperature could have an impact on the status or dynamics of a system. Thus, there is a great need for high-precision and large-dynamic-range temperature measurements. Conventional temperature sensors encounter difficulties in high-precision thermal sensing on the submicron scale. Recently, optical whispering-gallery mode (WGM) sensors have shown promise for many sensing applications, such as thermal sensing, magnetic detection, and biosensing. However, despite their superior sensitivity, the conventional sensing method for WGM resonators relies on tracking the changes in a single mode, which limits the dynamic range constrained by the laser source that has to be fine-tuned in a timely manner to follow the selected mode during the measurement. Moreover, we cannot derive the actual temperature from the spectrum directly but rather derive a relative temperature change. Here, we demonstrate an optical WGM barcode technique involving simultaneous monitoring of the patterns of multiple modes that can provide a direct temperature readout from the spectrum. The measurement relies on the patterns of multiple modes in the WGM spectrum instead of the changes of a particular mode. It can provide us with more information than the single-mode spectrum, such as the precise measurement of actual temperatures. Leveraging the high sensitivity of WGMs and eliminating the need to monitor particular modes, this work lays the foundation for developing a high-performance temperature sensor with not only superior sensitivity but also a broad dynamic range.

scholarly journals Time efficient laser modification of steel surfaces for advanced bonding in hybrid materials

2020 ◽  
Author(s):  
D. Voswinkel ◽  
D. Kloidt ◽  
O. Grydin ◽  
M. Schaper
Keyword(s):  
Adhesive Bonding ◽  
Scanning Speed ◽  
Laser Source ◽  
Lap Shear ◽  
Carbon Fibre Reinforced Polymer ◽  
Bonding Properties ◽  
Fibre Reinforced Polymer ◽  
Yvo4 Laser ◽  
Steel Surfaces ◽  
High Scanning Speed

AbstractLaser surface treatment of metals is one option to improve their properties for adhesive bonding. In this paper, a pulsed YVO4 Laser source with a wavelength of 1064 nm and a maximum power of 25 W was utilized to increase the surface area of the steel HCT490X in order to improve its bonding properties with a carbon fibre reinforced polymer (CFRP). Investigated was the influence of the scanning speed of the laser source on the bonding properties. For this purpose, the steel surfaces were ablated at a scanning speed between 1500 and 4500 mm/s. Afterwards the components were bonded with the adhesive HexBond™ 677. After lap shear tests were carried out on the specimen, the surfaces were inspected using scanning electron microscopy (SEM). The experiments revealed that the bonding quality can be improved with a high scanning speed, even when the surface is not completely ablated.

Effects of Weld Strength Mismatch on Estimation Procedures for J and CTOD Fracture Parameters Using SE(B) Specimens

2007 ◽  
Author(s):  
Gustavo H. B. Donato ◽  
Claudio Ruggieri
Keyword(s):  
Mouth Opening ◽  
Estimation Procedure ◽  
Primary Objective ◽  
Weld Strength ◽  
Crack Mouth Opening Displacement ◽  
Opening Displacement ◽  
Fracture Parameters ◽  
Wide Range ◽  
Estimation Procedures ◽  
Fracture Specimens

This work presents an exploratory development of J and CTOD estimation procedures for welded fracture specimens under bending based upon plastic eta factors and plastic rotation factors. The techniques considered include: i) estimating J and CTOD from plastic work and ii) estimating CTOD from the plastic rotational factor. The primary objective is to gain additional understanding on the effect of weld strength mismatch on estimation techniques to determine J and CTOD fracture parameters for a wide range of a/W-ratios and mismatch levels. Very detailed non-linear finite element analyses for plane-strain models of SE(B) fracture specimens with center cracked, square groove welds provide the evolution of load with increased load-line displacement and crack mouth opening displacement which are required for the estimation procedure. The results show that levels of weld strength mismatch within the range ±20% mismatch do not affect significantly J and CTOD estimation expressions applicable to homogeneous materials, particularly for deeply cracked fracture specimens. The present analyses, when taken together with previous studies, provide a fairly extensive body of results which serve to determine parameters J and CTOD for different materials using bend specimens with varying geometries and mismatch levels.

Quantitative Morphological Analysis of Carbon Black in Polymers used in Laser Transmission Welding

2007 ◽  
Vol 51 (3-4) ◽  
pp. 85-90 ◽  
Author(s):  
C. Y. Wang ◽  
P. J. Bates ◽  
M. Aghamirian ◽  
G. Zak ◽  
R. Nicholls ◽  
...  
Keyword(s):  
Carbon Black ◽  
Morphological Analysis ◽  
Laser Transmission Welding ◽  
Quantitative Morphological Analysis

scholarly journals The AAA+ ATPase p97, a cellular multitool

2017 ◽  
Vol 474 (17) ◽  
pp. 2953-2976 ◽  
Author(s):  
Lasse Stach ◽  
Paul S. Freemont
Keyword(s):  
Atp Hydrolysis ◽  
Current Status ◽  
Cellular Functions ◽  
Aaa Atpase ◽  
Cellular Processes ◽  
Proteotoxic Stress ◽  
Binding Domains ◽  
Wide Range ◽  
Aaa Atpases ◽  
Substrate Proteins

The AAA+ (ATPases associated with diverse cellular activities) ATPase p97 is essential to a wide range of cellular functions, including endoplasmic reticulum-associated degradation, membrane fusion, NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) activation and chromatin-associated processes, which are regulated by ubiquitination. p97 acts downstream from ubiquitin signaling events and utilizes the energy from ATP hydrolysis to extract its substrate proteins from cellular structures or multiprotein complexes. A multitude of p97 cofactors have evolved which are essential to p97 function. Ubiquitin-interacting domains and p97-binding domains combine to form bi-functional cofactors, whose complexes with p97 enable the enzyme to interact with a wide range of ubiquitinated substrates. A set of mutations in p97 have been shown to cause the multisystem proteinopathy inclusion body myopathy associated with Paget's disease of bone and frontotemporal dementia. In addition, p97 inhibition has been identified as a promising approach to provoke proteotoxic stress in tumors. In this review, we will describe the cellular processes governed by p97, how the cofactors interact with both p97 and its ubiquitinated substrates, p97 enzymology and the current status in developing p97 inhibitors for cancer therapy.

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