scholarly journals Nanomaterials for IoT Sensing Platforms and Point-of-Care Applications in South Korea

Sensors ◽  
2022 ◽  
Vol 22 (2) ◽  
pp. 610
Author(s):  
Seung-Ho Choi ◽  
Joon-Seok Lee ◽  
Won-Jun Choi ◽  
Jae-Woo Seo ◽  
Seon-Jin Choi
Keyword(s):  
South Korea ◽  
Chemical Sensing ◽  
Point Of Care ◽  
Chemical Species ◽  
Future Perspective ◽  
Fully Integrated ◽  
Signal Transducers ◽  
Sensing Platforms ◽  
Inorganic Nanomaterials ◽  
Art Research

Herein, state-of-the-art research advances in South Korea regarding the development of chemical sensing materials and fully integrated Internet of Things (IoT) sensing platforms were comprehensively reviewed for verifying the applicability of such sensing systems in point-of-care testing (POCT). Various organic/inorganic nanomaterials were synthesized and characterized to understand their fundamental chemical sensing mechanisms upon exposure to target analytes. Moreover, the applicability of nanomaterials integrated with IoT-based signal transducers for the real-time and on-site analysis of chemical species was verified. In this review, we focused on the development of noble nanostructures and signal transduction techniques for use in IoT sensing platforms, and based on their applications, such systems were classified into gas sensors, ion sensors, and biosensors. A future perspective for the development of chemical sensors was discussed for application to next-generation POCT systems that facilitate rapid and multiplexed screening of various analytes.

Nano-functionalized Paper-based IoT enabled Devices for Point-of-Care Testing: A Review

2021 ◽  
Author(s):  
Vinay Kishnani ◽  
Ankur Gupta
Keyword(s):  
Point Of Care ◽  
Research Work ◽  
Functional Materials ◽  
Point Of Care Testing ◽  
Environment Friendly ◽  
Iot Platform ◽  
Art Research ◽  
Detection Mechanisms ◽  
The Internet Of Things ◽  
Sensing Characteristics

Over the last few years, the microfluidics phenomenon coupled with the Internet of Things (IoT) using innovative nano-functional materials have been recognized as one of the sustainable and economical tools for point of care testing (POCT) of various pathogens influencing the human health. The sensors based on these phenomena are aimed to be designed for their cost-effectiveness, to make it handy, environment-friendly and to get an accurate, easy, and rapid response. Considering the burgeoning importance of analytical devices in the healthcare domain, this review paper is based on the gist of sensing aspects of the micro fabricated paper-based analytical devices (μPADs). The article discusses not only the various used design methodologies and fabrication approaches, but also elucidates the recently reported surface modification strategies, detection mechanisms viz., colorimetric, electrochemical, fluorescence, electrochemiluminescence etc., and sensing characteristics of μPADs along with reported works equipped with the IoT platform for digital readout. In a nutshell, this article summarizes the state-of-the-art research work carried out over the nano functionalized paper-based analytical devices and associated challenges/solutions in the point of care testing domain.

Social Interactions and Automated Detection Tools in Cyberbullying

2014 ◽  
pp. 1175-1195
Author(s):  
Michael J. Moore ◽  
Tadashi Nakano ◽  
Tatsuya Suda ◽  
Akihiro Enomoto
Keyword(s):  
Social Networking ◽  
Digital Media ◽  
Instant Messaging ◽  
Future Perspective ◽  
Chat Rooms ◽  
Face To Face ◽  
New Form ◽  
Art Research ◽  
Automated Tools ◽  
E Mail

Face-to-Face bullying is a traditional form of bullying in which bullies attack victims through physical, verbal, or social attacks. Cyberbullying is a new form of bullying. Cyberbullies abuse digital media to attack victims (such as attacks through websites, social networking services, blogging, e-mail, instant messaging, chat rooms, and cell phones). Cyberbullying and face-to-face bullying share many similarities. For example, bullies achieve power over a victim in both cyberbullying and face-to-face bullying. On the other hand, cyberbullying has differences from face-to-face bullying that arise from characteristics of digital media such as anonymity and rapid spreading of attacks. This chapter highlights key concerns of cyberbullying stemming from the use of digital media and discusses existing models of face-to-face bullying which may aid in model cyberbullying. This chapter then introduces state-of-the-art research in automated tools to detect cyberbullying. Finally, this chapter concludes with future perspective of research in automated tools to detect cyberbullying.

scholarly journals Lab-on-a-Chip Systems for Aptamer-Based Biosensing

Micromachines ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 220 ◽  
Author(s):  
Niazul I. Khan ◽  
Edward Song
Keyword(s):  
Point Of Care ◽  
Lab On A Chip ◽  
Review Article ◽  
Microfluidic Chips ◽  
High Affinity ◽  
Sensing Platforms ◽  
Personal Medicine ◽  
Paper Based Microfluidics ◽  
Recognition Elements ◽  
Analyte Detection

Aptamers are oligonucleotides or peptides that are selected from a pool of random sequences that exhibit high affinity toward a specific biomolecular species of interest. Therefore, they are ideal for use as recognition elements and ligands for binding to the target. In recent years, aptamers have gained a great deal of attention in the field of biosensing as the next-generation target receptors that could potentially replace the functions of antibodies. Consequently, it is increasingly becoming popular to integrate aptamers into a variety of sensing platforms to enhance specificity and selectivity in analyte detection. Simultaneously, as the fields of lab-on-a-chip (LOC) technology, point-of-care (POC) diagnostics, and personal medicine become topics of great interest, integration of such aptamer-based sensors with LOC devices are showing promising results as evidenced by the recent growth of literature in this area. The focus of this review article is to highlight the recent progress in aptamer-based biosensor development with emphasis on the integration between aptamers and the various forms of LOC devices including microfluidic chips and paper-based microfluidics. As aptamers are extremely versatile in terms of their utilization in different detection principles, a broad range of techniques are covered including electrochemical, optical, colorimetric, and gravimetric sensing as well as surface acoustics waves and transistor-based detection.

Development of Chemical Sensing Platforms Based on Sol−Gel-Derived Thin Films:  Origin of Film Age vs Performance Trade-Offs

1996 ◽  
Vol 68 (4) ◽  
pp. 604-610 ◽  
Author(s):  
Richard A. Dunbar ◽  
Jeffrey D. Jordan ◽  
Frank V. Bright
Keyword(s):  
Thin Films ◽  
Chemical Sensing ◽  
Sol Gel ◽  
Trade Offs ◽  
Sensing Platforms

Fiber-based chemical sensing and sensing platforms with colorimetric dyes

2018 ◽  
Author(s):  
Richard M. Osgood ◽  
Stephen Giardini ◽  
Conor Hennessy ◽  
Alexander Stolyarov ◽  
Richard Kingsborough ◽  
...  
Keyword(s):  
Chemical Sensing ◽  
Sensing Platforms

Chemical sensing platforms for detecting trace-level Alzheimer's core biomarkers

2020 ◽  
Vol 49 (15) ◽  
pp. 5446-5472 ◽  
Author(s):  
Kayoung Kim ◽  
Chang Heon Lee ◽  
Chan Beum Park
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Chemical Sensing ◽  
Electrical Detection ◽  
Trace Level ◽  
Disease Biomarkers ◽  
Recent Advances ◽  
Sensing Platforms

This review provides an overview of recent advances in optical and electrical detection of Alzheimer's disease biomarkers in clinically relevant fluids.

scholarly journals Fabrication of Patterned Integrated Electrochemical Sensors

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Muhammad Mujeeb-U-Rahman ◽  
Dvin Adalian ◽  
Axel Scherer
Keyword(s):  
Electrochemical Sensors ◽  
Measurement Techniques ◽  
Glucose Sensing ◽  
Small Surface ◽  
Fully Integrated ◽  
Nanoscale Patterning ◽  
Sensing Applications ◽  
Sensing Platforms ◽  
Integrated Microsystems ◽  
Electronic Measurement

Fabrication of integrated electrochemical sensors is an important step towards realizing fully integrated and truly wireless platforms for many local, real-time sensing applications. Micro/nanoscale patterning of small area electrochemical sensor surfaces enhances the sensor performance to overcome the limitations resulting from their small surface area and thus is the key to the successful miniaturization of integrated platforms. We have demonstrated the microfabrication of electrochemical sensors utilizing top-down lithography and etching techniques on silicon and CMOS substrates. This choice of fabrication avoids the need of bottom-up techniques that are not compatible with established methods for fabricating electronics (e.g., CMOS) which form the industrial basis of most integrated microsystems. We present the results of applying microfabricated sensors to various measurement problems, with special attention to their use for continuous DNA and glucose sensing. Our results demonstrate the advantages of using micro- and nanofabrication techniques for the miniaturization and optimization of modern sensing platforms that employ well-established electronic measurement techniques.

A Lab-on-a-Chip for Clinical Analysis with Acoustic Microagitation based on Piezoelectric Poly(Vinilidene Fluoride)

2008 ◽  
Vol 1138 ◽  
Author(s):  
P. Martins ◽  
V. Cardoso ◽  
J. Serrado Nunes ◽  
L. Rebouta ◽  
G. Rocha ◽  
...  
Keyword(s):  
Vinylidene Fluoride ◽  
Biological Fluids ◽  
Point Of Care ◽  
Lab On A Chip ◽  
Beta Phase ◽  
Clinical Analysis ◽  
Fully Integrated ◽  
Quantitative Measurements ◽  
Novel Approach ◽  
Poly Vinylidene Fluoride

AbstractThis paper reports on the incorporation and validation of a microagitation system based on a piezoelectric polymer, Poly(vinylidene fluoride) in its beta phase, β-PVDF, in a fully-integrated disposable lab-on-a-chip for point-of-care testing and monitoring of biochemical parameters in biological fluids. The lab-on-a-chip concept offers a novel approach for clinical analyses, especially in biological fluids analyses, due to its portability, ensuring that the analysis can be performed at any location with quick results. Its microagitation system performance was successfully demonstrated by quantitative measurements of uric acid in human urine, though other molecules or biological fluids can be also measured. The optimization tests prove that it is possible to use lower frequencies than resonance with no major changes in the mixing process. The effect of area and location within the lab-on-a-chip of the microagitation system was also considered.

scholarly journals Cytokine and Cancer Biomarkers Detection: The Dawn of Electrochemical Paper-Based Biosensor

Sensors ◽  
2020 ◽  
Vol 20 (7) ◽  
pp. 1854 ◽  
Author(s):  
Song Wei Loo ◽  
Tze-Sian Pui
Keyword(s):  
Point Of Care ◽  
Cancer Biomarkers ◽  
Healthcare Services ◽  
Vital Role ◽  
Qualitative Assessment ◽  
Detection Methods ◽  
Societal Implications ◽  
Factors Affecting ◽  
Point Of Care Diagnostics ◽  
Sensing Platforms

Although the established ELISA-based sensing platforms have many benefits, the importance of cytokine and cancer biomarkers detection for point-of-care diagnostics has propelled the search for more specific, sensitive, simple, accessible, yet economical sensor. Paper-based biosensor holds promise for future in-situ applications and can provide rapid analysis and data without the need to conduct in a laboratory. Electrochemical detection plays a vital role in interpreting results obtained from qualitative assessment to quantitative determination. In this review, various factors affecting the design of an electrochemical paper-based biosensor are highlighted and discussed in depth. Different detection methods, along with the latest development in utilizing them in cytokine and cancer biomarkers detection, are reviewed. Lastly, the fabrication of portable electrochemical paper-based biosensor is ideal in deliberating positive societal implications in developing countries with limited resources and accessibility to healthcare services.

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