scholarly journals Global Analysis of Durable Policies for Free-Flowing River Protections

2021 ◽  
Vol 13 (4) ◽  
pp. 2347 ◽  
Author(s):  
Denielle Perry ◽  
Ian Harrison ◽  
Stephannie Fernandes ◽  
Sarah Burnham ◽  
Alana Nichols
Keyword(s):  
Global Analysis ◽  
Freshwater Ecosystems ◽  
Global Networks ◽  
Protection Mechanisms ◽  
The Creation ◽  
River Conservation ◽  
Protected Area Planning ◽  
Policy Types ◽  
Policy Mechanisms

Freshwater ecosystems are poorly represented in global networks of protected areas. This situation underscores an urgent need for the creation, application, and expansion of durable (long-term and enforceable) protection mechanisms for free-flowing rivers that go beyond conventional protected area planning. To address this need, we must first understand where and what types of protections exist that explicitly maintain the free-flowing integrity of rivers, as well as the efficacy of such policy types. Through policy analysis and an in-depth literature review, our study identifies three main policy mechanisms used for such protections: (1) River Conservation Systems; (2) Executive Decrees and Laws; and (3) Rights of Rivers. We found that globally only eight counties have national river conservation systems while seven countries have used executive decrees and similar policies to halt dam construction, and Rights of Rivers movements are quickly growing in importance, relative to other protection types. Despite the current extent of protection policies being insufficient to tackle the freshwater and biodiversity crises facing the world’s rivers, they do provide useful frameworks to guide the creation and expansion of protections. Ultimately, as countries act on global calls for protections, policy mechanisms must be tailored to their individual social and ecological geographies.

From Start-Up to Scale-Up

2018 ◽  
Author(s):  
Gilles Duruflé ◽  
Thomas Hellmann ◽  
Karen Wilson
Keyword(s):  
United States ◽  
Conceptual Framework ◽  
Public Policies ◽  
Scale Up ◽  
The United States ◽  
Smart Money ◽  
Start Up ◽  
The Us ◽  
The Creation

This chapter examines the challenge for entrepreneurial companies of going beyond the start-up phase and growing into large successful companies. We examine the long-term financing of these so-called scale-up companies, focusing on the United States, Europe, and Canada. The chapter first provides a conceptual framework for understanding the challenges of financing scale-ups. It emphasizes the need for investors with deep pockets, for smart money, for investor networks, and for patient money. It then shows some data about the various aspects of financing scale-ups in the United States, Europe, and Canada, showing how Europe and Canada are lagging behind the US relatively more at the scale-up than the start-up stage. Finally, the chapter raises the question of long-term public policies for supporting the creation of a better scale-up environment.

scholarly journals Hymenoptera Venom Immunotherapy: Immune Mechanisms of Induced Protection and Tolerance

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1575
Author(s):  
Ajda Demšar Luzar ◽  
Peter Korošec ◽  
Mitja Košnik ◽  
Mihaela Zidarn ◽  
Matija Rijavec
Keyword(s):  
Current Knowledge ◽  
Allergic Diseases ◽  
Hymenoptera Venom ◽  
Venom Immunotherapy ◽  
Effector Cells ◽  
Immune Mechanisms ◽  
Protection Mechanisms ◽  
Sting Challenge ◽  
Effectiveness Data

Hymenoptera venom allergy is one of the most severe allergic diseases, with a considerable prevalence of anaphylactic reaction, making it potentially lethal. In this review, we provide an overview of the current knowledge and recent findings in understanding induced immune mechanisms during different phases of venom immunotherapy. We focus on protection mechanisms that occur early, during the build-up phase, and on the immune tolerance, which occurs later, during and after Hymenoptera venom immunotherapy. The short-term protection seems to be established by the early desensitization of mast cells and basophils, which plays a crucial role in preventing anaphylaxis during the build-up phase of treatment. The early generation of blocking IgG antibodies seems to be one of the main reasons for the lower activation of effector cells. Long-term tolerance is reached after at least three years of venom immunotherapy. A decrease in basophil responsiveness correlates with tolerated sting challenge. Furthermore, the persistent decline in IgE levels and, by monitoring the cytokine profiles, a shift from a Th2 to Th1 immune response, can be observed. In addition, the generation of regulatory T and B cells has proven to be essential for inducing allergen tolerance. Most studies on the mechanisms and effectiveness data have been obtained during venom immunotherapy (VIT). Despite the high success rate of VIT, allergen tolerance may not persist for a prolonged time. There is not much known about immune mechanisms that assure long-term tolerance post-therapy.

Technology and Employment in Developing Countries

1978 ◽  
Vol 16 (4) ◽  
pp. 549-564 ◽  
Author(s):  
J. W. Garmany
Keyword(s):  
Developing Countries ◽  
Optimum Combination ◽  
Current Consumption ◽  
The Creation ◽  
Relationship Of ◽  
The Relationship ◽  
Choice Of Technology

This article discusses some of the issues involved in the choice of technology in developing countries, especially those in Africa, and the relationship of this to employment and output. The problem is to find an optimum combination of productive resources that comes nearest to satisfying two objectives: the full and economically efficient utilisation of such resources, and the creation of as much surplus as possible over current consumption, thereby making possible new investment and long-term growth.

Pandora's Box: Reviewing the Composition of the UN Security Council in the Light of British and French Experience 1945–1963

1997 ◽  
Vol 66 (2-3) ◽  
pp. 273-300 ◽  
Author(s):  
Keyword(s):  
Security Council ◽  
Status Quo ◽  
Short Term ◽  
French Experience ◽  
Un Security Council ◽  
The Status ◽  
The Creation ◽  
Foreign Ministries

AbstractThis article aims to throw a light on the problems relating to the proposed enlargement of the composition of the UN Security Council at present by studying the creation of four non-permanent seats in the Security Council in 1963 from the British and the French perspectives. The examination is based on the author's research of original documents in the archives of the British and French foreign ministries and upon information provided to the author by British, French and Finnish diplomats. The author concludes that, as between 1946 and 1963, British and French short term interests are still best served by maintaining the status quo in the Security Council. However, in a long term perspective it is not clear where the interests of these two States lie.

International Legal Sanction Processes

2005 ◽  
Author(s):  
Jordan Paust
Keyword(s):  
International Law ◽  
Institutional Settings ◽  
Legal Sanction ◽  
Long Term Consequences ◽  
The Creation

This article views international legal sanction processes as richly varied and dynamic, involving numerous types of participants, with various sanction objectives, operating in both formal and less formal fora or processes, utilizing various types of resources, with varied effects and long-term consequences. It identifies certain areas of debate and suggests a future scholarly agenda. With that in mind, it is evident that increasing attention to the creation, shaping, and efficacy of international law outside such traditional institutional settings should be part of a future scholarly agenda regardless of one's jurisprudential bias. The discussion covers participants in the sanction process, sanction objectives, formal fora, less formal processes, and more specific sanction strategies or problems.

Verbalization and musical memory in string players

2017 ◽  
Vol 23 (2) ◽  
pp. 212-230
Author(s):  
Eric Timperman ◽  
Peter Miksza
Keyword(s):  
Recall Performance ◽  
Experimental Conditions ◽  
Immediate Recall ◽  
Short And Long Term ◽  
The Creation ◽  
24 Hour Recall ◽  
Associative Recall ◽  
Verbal Analysis ◽  
Musical Memory

The purpose of this study was to examine the effect of verbalization about a brief etude on collegiate string players’ short- and long-term recall of the etude in question. We examined competing hypotheses that suggest it is possible that verbalization (i.e., verbal analysis of musical features) (a) could aid in recall both by highlighting patterns and constraints that inform the music’s creation and by facilitating the creation of explicit performance cues that help to bridge gaps between associative recall chains or (b) may hinder recall by interfering with the creation of procedural and auditory memories necessary for musical performance. Participants ( N = 20) were assigned to experimental conditions in which they learned an unfamiliar etude either through repetition alone or through repetition followed by the completion of a verbalization worksheet provided by the experimenter. Recall was tested both immediately following initial practice and 24 hours later to examine the effect of verbalization on both short- and long-term retention. Findings indicated no differences between groups on immediate recall performance but significant differences at the 24-hour recall task with participants in the verbalization condition recalling more material. In addition, the patterns of errors found across groups indicated a strong primacy effect. Theoretical implications for the study of memory processes in musical contexts and practical implications regarding the preparation of memorized performance are discussed.

scholarly journals Closest and long-term prospects of 3D-printing for obstetrics and gynecology

2021 ◽  
Vol 20 (1) ◽  
pp. 76-81
Author(s):  
E. V. Kudryavtseva ◽  
V. V. Kovalev ◽  
E. S. Zakurinova ◽  
G. Muller-Kamskii ◽  
V. V. Popov
Keyword(s):  
3D Printing ◽  
Scientific Literature ◽  
Simulation Models ◽  
Surgical Instruments ◽  
Obstetrics And Gynecology ◽  
Scientific Review ◽  
Advantages And Disadvantages ◽  
The Creation ◽  
Dimensional Printing

Introduction. Despite the notable and rapid progress in the development of medical 3D printing in recent years, not much is known about the use of this technology in obstetrics and gynecology.The purpose of our review of scientific literature was to determine the current level of 3D printing development, discuss the closest and long term prospects for using this technology in obstetrics and gynecology, and analyze its potential advantages and disadvantages.Materials and methods. We searched for scientific literature. 378 papers passed a three-step screening, as a result of which 42 sources were selected for the final scientific review.Results and discussion. The main areas in which dimensional printing can be used in this area of medicine is the creation of simulation models and training for students, the creation of anatomical models for preoperative preparation, the surgical instruments, the creation of new dosage drug forms (including transvaginal ones), and bioprinting of organs and tissues.Conclusion. The presented literary review allows us to conclude that 3D printing the obstetrics and gynecology is a current rapidly developing direction. The organization of 3D modeling and printing laboratories can significantly increase the efficiency of teaching students and residents. In addition, obstetricians-gynecologists and surgeons should be informed about the possibility of 3D printing surgical instruments according to an individual design. It can inspire them to implement their own ideas and develop domestic innovative developments. Three-dimensional printing of dosage forms and bioprostheses requires more complex technological solutions, and is not yet used in clinical practice. However, given the enormous prospects for these areas, various grants should be envisaged for their development in Russia

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