scholarly journals A Novel Adsorbent Albite Modified with Cetylpyridinium Chloride for Efficient Removal of Zearalenone

Toxins ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 674 ◽  
Author(s):  
Zhang ◽  
Zhang ◽  
Wang ◽  
Dong ◽  
Cheng ◽  
...  
Keyword(s):  
Cetylpyridinium Chloride ◽  
Kinetic Studies ◽  
Xrd Analysis ◽  
Sem Analysis ◽  
Maximum Adsorption Capacity ◽  
Potential Health ◽  
Adsorption Data ◽  
Ph Conditions ◽  
Mycotoxin Adsorbent

Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin and constitutes a potential health threat to humans and livestock. This study aimed to explore the potential of albite modified by the cationic surfactant cetylpyridinium chloride (CPC) as ZEN adsorbent. The organoalbite (OA) was characterized by SEM analysis, XRD analysis, FTIR spectroscopy, thermal analysis, and BET gas sorption measurement. In vitro adsorption of ZEN by OA was carried out by simulating the pH conditions of the gastrointestinal tract. The characterization results showed that the surface of OA changed from hydrophilic to hydrophobic after modification. Adsorption kinetic studies showed that ZEN adsorption behavior of OA occurred by chemisorption. The equilibrium adsorption data fitted well with the Langmuir isotherm, indicating that the adsorption process of ZEN by OA was monolayer. The maximum adsorption capacity (qm) values of OA for ZEN were 10.580 and 9.287 mg/g at pH 7 and pH 3, respectively. In addition, OA had a low desorption rate (about 2%), and co-existing amino acids (i.e., Lys and Met), vitamins (i.e., VB1 and VE), and minerals (i.e., Fe2+ and Ca2+) did not affect the removal of ZEN. These results demonstrate that OA could be a promising mycotoxin adsorbent for removing the hydrophobic, weakly polar ZEN.

Lead Adsorption from Aqueous Solution Using Manganese Oxides Recovered from Spent Alkaline Batteries

2020 ◽  
Vol 46 (3) ◽  
pp. 206-212
Author(s):  
Franco Medici ◽  
María Silvina Patterer ◽  
Miguel Andrés Peluso ◽  
Jorge Enrique Sambeth
Keyword(s):  
Manganese Oxides ◽  
Kinetic Studies ◽  
Xrd Analysis ◽  
Maximum Adsorption Capacity ◽  
Order Kinetic ◽  
Lead Adsorption ◽  
Alkaline Batteries ◽  
Batch Tests ◽  
Order Kinetic Model ◽  
Different Temperatures

Lead is a highly toxic element and can cause serious illnesses, as a consequence of this, stringent limits have been set for this element, especially regarding drinking water. In this paper, the potential of manganese oxides (MnOx) as adsorbents for the removal of lead (as Pb II) from synthetically contaminated water was investigated. These oxides were recovered from alkaline batteries by a bio-hydrometallurgical process through potassium permanganate (KMnO4) precipitation. The MnOx was characterized by Scanning Electronic Microscopy (SEM), Energy Dispersive Spectroscopy (SEM-EDS) and X Ray Diffraction (XRD) analysis. The surface area of the material was determined using the N2 isotherm by the BET method. Batch tests were performed on untreated manganese oxides at different temperatures (10, 25 and 40°C), utilizing initial adsorbate concentration ranging from 5 to 100 mg L-1 and contact times between 1 minute and 30 minutes. The Langmuir isotherm provided the best correlation for the adsorption process, with a maximum adsorption capacity of 9.51 (mg g–1) at 10 °C. Kinetic studies revealed that the lead adsorption onto MnOx followed a pseudo-second order kinetic model, while the thermodynamic study has highlighted that the adsorption of lead is exothermic and spontaneous.

scholarly journals Synthesis of Magnetic Multiwalled Carbon Nano Tubes and Investigation of isotherm and kinetic models for cleanup of Carbaryl pesticide

2020 ◽  
Keyword(s):  
Kinetic Models ◽  
High Efficiency ◽  
Kinetic Studies ◽  
Xrd Analysis ◽  
Maximum Adsorption Capacity ◽  
Multiwalled Carbon ◽  
Pseudo Second Order ◽  
Carbon Nano Tubes ◽  
Isotherm And Kinetic Models ◽  
Main Factor

<p>Abstract: Water is the main factor of movement and transport of pesticides and contamination of water by these pollutants is one of the most important challenges due to their widespread use and increased concentrations. Moreover, these compounds are on the U.S.EPA Priority Pollutant list because of the potential of accumulation and the property of damaging effects. In this study, multiwalled carbon nanotube-based magnetic nanoparticles were synthesized and used as an affective adsorbent for carbaryl pesticide. The properties of the synthesized Fe3O4@MWCNTs were characterized by TEM images and XRD analysis. The obtained data were studied by isotherm and kinetic models. Carbaryl adsorbed onto the synthesized adsorbent was compatible with the Langmuir isotherm (R2 =0.993). The maximum adsorption capacity (qmax) of the pesticide onto the Fe3O4-MWCNTs was obtained at 68.2 mg/g. The kinetic studies of the reactions showed that the adsorption process followed the pseudo-second order model with R2 ≥0.99 for all initial carbaryl concentrations. The adsorbent was extracted by magnet reused several times (six rounds) with a reasonable efficiency. The Fe3O4-MWCNTs have great potential for adsorption of carbaryl from water and wastewater due to high efficiency, easy separation and reusability.</p>

scholarly journals “FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES OF PREDNISOLONE”

2019 ◽  
Vol 8 (3) ◽  
Author(s):  
Chirayu. C ◽  
Nagaraja T.S ◽  
Vitthal K Vijapure
Keyword(s):  
Drug Release ◽  
Xanthan Gum ◽  
Guar Gum ◽  
Research Work ◽  
In Vitro Study ◽  
Xrd Analysis ◽  
Sem Analysis ◽  
Drug Content ◽  
Free Films

The purpose of this research work was to develop and evaluate transdermal patch of Prednisolone, using Xanthan gum, Guar gum and Polyacrylamide in different ratios prepared by the Glass Substrate Technique. The physicochemical compatibility of the polymers and the drug was evaluated by FTIR. The results suggested that no physicochemical incompatibility between the polymer and the drug. Drug free films were formulated and evaluated characteristics like flexibility and smoothness. Further drug loaded films were formulated and evaluated for thickness, weight uniformity, drug content, folding endurance and drug release. The XRD analysis confirmed the amorphous dispersion of the drug in the formulation. SEM analysis showed surface morphology of prepared formulations. Drug diffusion through cellophane membrane was carried out using Franz diffusion cell by in-vitro study. The film prepared with formulation PDS 9 showed maximum diffusion release at the end of 24 hours. It is shown that drug release follows order and non Fikinian mechanism of release diffusion. The PDS 9 formulation was found to be stable with respect to drug content as well as physical changes at 40 ºC and 75 % RH. Keywords: Transdermal drug delivery, Prednisolone, Xanthan gum, Guar gum, Polyacrylamide.

scholarly journals Modified biochar from Moringa seed powder for the removal of diclofenac from aqueous solution

2019 ◽  
Vol 27 (7) ◽  
pp. 7318-7327 ◽  
Author(s):  
Afrouz Bagheri ◽  
Emmanuel Abu-Danso ◽  
Jibran Iqbal ◽  
Amit Bhatnagar
Keyword(s):  
Aqueous Solution ◽  
Sem Analysis ◽  
Parent Material ◽  
Point Of Zero Charge ◽  
Maximum Adsorption Capacity ◽  
Ftir Analysis ◽  
Modified Biochar ◽  
Pseudo Second Order ◽  
Ph Conditions ◽  
Synthesized Materials

AbstractIn this study, Moringa seed powder (MSP) was pyrolyzed at 450 °C to synthesize Moringa seed powder biochar (MSPB) and treated with phosphoric acid (H3PO4) to synthesize phosphate-modified Moringa seed powder biochar (MSPB-HPO) as an adsorbent for the removal of diclofenac (Dfc) from aqueous solution. Fourier transform infrared (FTIR) analysis, energy dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), and pH point of zero charge (pHpzc) were conducted to give more insight into the adsorbent’s properties. The SEM analysis showed the transformations in the surface morphology from the parent material to the synthesized materials after the thermal and acid treatment. EDS analysis revealed the variation in the elemental composition of the materials prior to and after adsorption of Dfc ions. The FTIR analysis showed changes and peak intensities of functional groups involved in Dfc removal. The pHpzc showed the charge carried by MSPB-HPO in different pH conditions. Isotherm data best matched the Sips model, and the pseudo-second-order model best described the adsorption kinetics. The maximum adsorption capacity of MSPB-HPO by Sips model was found to be 100.876 mg g−1.

scholarly journals Structural, mechanical and in vitro studies on pulsed laser deposition of hydroxyapatite on additive manufactured polyamide substrate

2016 ◽  
Vol 2 (2) ◽  
Author(s):  
Hariharan Kuppuswamy ◽  
Arumaikkannu Ganesan
Keyword(s):  
Pulsed Laser Deposition ◽  
Calcium Phosphates ◽  
Pulsed Laser ◽  
Building Blocks ◽  
Xrd Analysis ◽  
Sem Analysis ◽  
Laser Deposition ◽  
Biological Fixation ◽  
Pull Out

Additive manufacturing (AM) is an emerging field that merges engineering and life sciences to produce components that can effectively act as a replacement in the human body. This AM encompasses biofabrication using cells, biological or biomaterials as building blocks to fabricate biological and bio-application oriented substance, device and therapeutic products through a broad range of engineering and biological processes. Furthermore, bioactive coating on BAM surface facilitates biological fixation between the prosthesis and the hard tissue which increases the long term stability and integrity of the implant. In this paper, hydroxyapatite (HA) powder was coated over AM polyamide sub-strate using pulsed laser deposition. Coating morphology was characterised using scanning electron microscope (SEM) analysis and observed that the coating was dominated by the presence of particle droplet with different sizes. Com-pounds like tricalcium phosphate and a few amorphous calcium phosphates were found along with HA which was con-firmed by X-ray diffraction (XRD) analysis. Fourier transform infrared spectroscopy (FTIR) techniques shows the presence of phosphate and carbonate groups in the HA structure. Nano-indentation and pull-out test reveals that the layer was strong enough and withstands higher load before it peels off. In vitro analysis was evaluated with human os-teosarcoma MG-63 cells with respect to the cell viability and results shows that the good viability was observed on coated surface due to combinational effect of Ca2+ and PO43? ions. The multitude of characterisation conducted on the coating has established that coating polyamide with HA results in a positive combination for an implant.

scholarly journals Impact of silver nanoparticles as antibacterial agent derived from leaf and callus of Celastrus paniculatus Willd

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Anita Solanki ◽  
Dipika Rathod ◽  
Illa C. Patel ◽  
Jitendriya Panigrahi
Keyword(s):  
Silver Nanoparticles ◽  
Xrd Analysis ◽  
Sem Analysis ◽  
Drug Preparation ◽  
Electron Microscopic ◽  
Colored Complex ◽  
Celastrus Paniculatus ◽  
Antibacterial Potential

Abstract Background Celastrus paniculatus Willd. is a rich source of numerous active constituents such as celapanigin, celapagin, malkangunin, celapanin, zeylasteral, pristimerin, and zeylasterone which render medicinal properties to its various parts. Therefore, the present work provides a protocol for the synthesis of AgNPs from in vivo leaf and in vitro developed callus extract of C. paniculatus and both the extracts have great antibacterial potential, which may give immense support for the drug preparation using AgNPs prepared from this valuable medicinal plant. Results High frequencies of calli induced from leaves and its counterpart, i.e., the natural part leaf were selected as the experimental materials for the green synthesis. The collected data exhibited gradual color variations started with whitish color, creamish, and after 8 weeks it ultimately turns into a solid mass of brownish callus. The silver nanoparticles (AgNPs) were synthesized using in vivo fresh leaves and in vitro developed callus extracts with an indication of brown colored complex. Further confirmation of AgNPs synthesis in both the samples was done using UV-visible spectral analysis followed by X-ray diffraction (XRD) analysis, Fourier transformation infrared spectroscopy (FTIR), and scanning electron microscopic (SEM) analysis. Conclusion The antibacterial activity of both extracts reflected the presence of the zone of inhibition in both gram-positive and gram-negative bacteria. AgNPs derived from callus extract showed better results with 24.00 ± 1.00 mm zones of inhibition. This protocol deserves the recognition of the antibacterial potential of AgNPs synthesized from CP plant extracts.

scholarly journals The Effectiveness of Durian Peel as a Multi-Mycotoxin Adsorbent

Toxins ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 108 ◽  
Author(s):  
Saowalak Adunphatcharaphon ◽  
Awanwee Petchkongkaew ◽  
Donato Greco ◽  
Vito D’Ascanio ◽  
Wonnop Visessanguan ◽  
...  
Keyword(s):  
Surface Area ◽  
Structural Changes ◽  
Agricultural Waste ◽  
Fumonisin B1 ◽  
Maximum Adsorption Capacity ◽  
Inorganic Pollutant ◽  
Ft Ir ◽  
Mycotoxin Adsorbent ◽  
Dose Dependent

Durian peel (DP) is an agricultural waste that is widely used in dyes and for organic and inorganic pollutant adsorption. In this study, durian peel was acid-treated to enhance its mycotoxin adsorption efficacy. The acid-treated durian peel (ATDP) was assessed for simultaneous adsorption of aflatoxin B1 (AFB1), ochratoxin A (OTA), zearalenone (ZEA), deoxynivalenol (DON), and fumonisin B1 (FB1). The structure of the ATDP was also characterized by SEM–EDS, FT–IR, a zetasizer, and a surface-area analyzer. The results indicated that ATDP exhibited the highest mycotoxin adsorption towards AFB1 (98.4%), ZEA (98.4%), and OTA (97.3%), followed by FB1 (86.1%) and DON (2.0%). The pH significantly affected OTA and FB1 adsorption, whereas AFB1 and ZEA adsorption was not affected. Toxin adsorption by ATDP was dose-dependent and increased exponentially as the ATDP dosage increased. The maximum adsorption capacity (Qmax), determined at pH 3 and pH 7, was 40.7 and 41.6 mmol kg−1 for AFB1, 15.4 and 17.3 mmol kg−1 for ZEA, 46.6 and 0.6 mmol kg−1 for OTA, and 28.9 and 0.1 mmol kg−1 for FB1, respectively. Interestingly, ATDP reduced the bioaccessibility of these mycotoxins after gastrointestinal digestion using an in vitro, validated, static model. The ATDP showed a more porous structure, with a larger surface area and a surface charge modification. These structural changes following acid treatment may explain the higher efficacy of ATDP in adsorbing mycotoxins. Hence, ATDP can be considered as a promising waste material for mycotoxin biosorption.

Insulin secretion in the spiny mouse (Acomys cahirinus). Dose and time kinetic studies with glucose in vivo and in vitro

Diabetes ◽  
1975 ◽  
Vol 24 (12) ◽  
pp. 1094-1100 ◽  
Author(s):  
A. Rabinovitch ◽  
A. Gutzeit ◽  
A. E. Renold ◽  
E. Cerasi
Keyword(s):  
Insulin Secretion ◽  
Kinetic Studies ◽  
Spiny Mouse ◽  
Acomys Cahirinus

Gastroretentive System of Fluvastatin Sodium by Using Natural Mucilage and Synthetic Polymer

2014 ◽  
Vol 4 (2) ◽  
Author(s):  
Umamaheswara G. ◽  
Anudeep D.
Keyword(s):  
Half Life ◽  
Release Kinetics ◽  
Kinetic Studies ◽  
Diffusion Path ◽  
Synthetic Polymer ◽  
In Vitro Dissolution ◽  
Direct Compression ◽  
Drug Content ◽  
Biological Half Life

Fluvastatin sodium is a novel compound used as cholesterol lowering agent which acts through the inhibition of 3- hydroxyl-3- methyl glutaryl- coenzyme A (HMG-Co A) reductase. It has short biological half life (1-3h) in humans required a dosing frequency of 20 to 40mg twice a day. Due to its short variable biological half life it has been developed to a sustained gastroretentive system with a natural and synthetic polymer and to study how far the natural mucilage improves the sustained activity. Floating tablets were prepared by direct compression method using in combination of natural mucilage and synthetic polymer. Prior to the preparation of tablets the physical mixtures were subjected to FT IR studies and pre compression parameters. After preparation of tablets they were subjected to various tests like swollen index, drug content, In vitro dissolution and release kinetics with pcp disso software etc. The tablets prepared by direct compression shown good in thickness, hardness and uniformity in drug content, the prepared tablets floated more than 12h except FS1 and FS2 shows 9 and 11h. Swollen index studies shows with increase in concentration of polymer the swelling increases the diffusion path length by which the drug molecule may have to travel and cause lag time. In vitro results shows that on increasing the amount of hibiscus polymer the sustain activity is increased because of its integrity and forms a thick swollen mass and reduces the erosion property of the HypromelloseK100M, kinetic studies shows that FS 1, FS2, FS3 followed the Korsmeyer peppas model and the rest FS 4, FS 5, FS6 follows the zero order respectively. Based on n value indicating that the drug release followed super case II transport mechanism due to the erosion of the polymer.

Functionalized Nano-graphene Oxide as Multi-modal Clinic for Effective Drug Delivery

2017 ◽  
Vol 10 (4) ◽  
pp. 3768-3771
Author(s):  
Soumitra Satapathi ◽  
Rutusmita Mishra ◽  
Manisha Chatterjee ◽  
Partha Roy ◽  
Somesh Mohapatra
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Cancer Cell ◽  
High Surface ◽  
High Surface Area ◽  
Cancer Cell Line ◽  
Xrd Analysis ◽  
Graphene Derivatives ◽  
Nano Graphene

Nano-materials based drug delivery modalities to specific organs and tissues has become one of the critical endeavors in pharmaceutical research. Recently, two-dimensional graphene has elicited considerable research interest because of its potential application in drug delivery systems. Here we report, the drug delivery applications of PEGylated nano-graphene oxide (nGO-PEG), complexed with a multiphoton active and anti-cancerous diarylheptanoid drug curcumin. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug curcumin due to its high surface area and easy surface functionalization. nGO was synthesized by modified Hummer’s method and confirmed by XRD analysis. The formation of nGO, nGO-PEG and nGO-PEG-Curcumin complex were monitored through UV-vis, IR spectroscopy. MTT assay and AO/EB staining found that nGO-PEG-Curcumin complex afforded highly potent cancer cell killing in vitro with a human breast cancer cell line MCF7.

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