The use of probiotics for the correction of disturbances of metabolism in cows

Author(s):  
O. V. Kovaleva ◽  
N. V. Sannikova ◽  
О. V. Shulepova ◽  
N. M. Kostomakhin ◽  
Yu. A. Karmatskikh

Currently, there is a huge range of different feed additives on the market, which are widely used in animal husbandry, but they act simultaneously, i. e. by stopping their use the resulting effect is also lost. Metabolic disorders due to feeding errors begin imperceptibly without any precursors, and first of all this affects the biochemical parameters of the blood only later leads to alimentary diseases with deep often irreversible degenerative changes in organs and tissues. In practice, there are rarely disorders of any one type of metabolism more often there are combinations of various metabolic disorders, especially often this occurs in the absence of a complete balanced feeding. The purpose of the work was to evaluate the effectiveness of the use of a probiotic drug based on Bacillus subtilis in the watering of lactating cows for the correction of metabolic disorders. In order to assess the actual presence of probiotics in the water during the experiment its analysis has been carried out. It has shown that in the water that enters the distribution tank the total microbial number was 9×10[sup]5[/sup] CFU/ml, and in the drinker this indicator was at the level of 3,8×10[sup]5[/sup] CFU/ml. Common coliform bacteria and thermotolerant coliform bacteria have been not detected. Studies have shown that when using the drug based on Bacillus subtilis containing five strains of bacteria in an amount of 0,01 %, which is 6 ml/head/day in the watering of lactating cows during the increasing the milk yield period there was a tendency to correct metabolic disorders. There was the decrease in the content of ketone bodies by 11,9 %, the increase in glucose by 34 % and the decrease in urea by 7,1 mmol/l.

Author(s):  
L. P. Yarmots ◽  
G. A. Yarmots ◽  
A. E. Belenkaya ◽  
M. O. Smyshlyaeva

Unbalanced mineral and vitamin nutrition of lactating cows can be a critical factor in the realization of their productive potential. The development and introduction into production of inexpensive, but effective feed additives is the main trend of improving the feeding of modern animal husbandry. Under the conditions of the Tyumen region such natural raw materials can be sapropels, which successfully combine a variety of biologically active substances. The purpose of the research was to study the digestibility of nutrients and energy metabolism in lactating cows when sapropel is included in the ration. Scientifi c and economic experiment in the study of the effectiveness of feeding sapropel lake Nepryak has been carried out in the training and experimental farm of the State Northern Trans-Urals Agrarian University. The animals of the control group have been fed the main diet. Cows of the 1st and 2nd experimental groups have been fed 300 and 500 g of sapropel per head/day, respectively, in addition to the main ration. It has been found as a result of research that the introduction of sapropel into the ration of cows has a positive effect on the digestibility of nutrients. The digestibility coefficients were higher in the animals of the 1st and 2nd experimental groups compared with the cows of the control group. Cows from the experimental groups digested all the organic substances of the ration better. During the experiment period cows of the 1st and 2nd experimental groups in contrast to the control group had higher milk yield by 11,31 and 10,38 %, respectively, milk protein yield by 10,56 and 5,95 %, milk fat yield by 17,18 and 12,99 %. It has been established that the introduction of sapropel into the ration of cows has the positive effect on the digestibility of nutrients, contributes to the increase of milk productivity, normalizes the metabolism in the body.


1985 ◽  
Vol 52 (3) ◽  
pp. 379-389 ◽  
Author(s):  
Alex S. A. Thomas ◽  
Lloyd R. Fell

SUMMARYSix dairy cows were treated before milkings with either oxytocin (Pitocin, 20 i.u.) or ACTH (Synacthen, 150 i.u.), principally to determine their effect on the ratio of citrate:lactoferrin concentrations in the milk. With ACTH treatment, after 3 d milk yield and citrate concentration decreased significantly, lactoferrin and bovine serum albumin (BSA) concentrations increased significantly. Somatic cell counts (SCC) increased temporarily in the milk of three of the cows which previously had > 100000 cells/ml. Lactoferrin yield remained fairly constant but citrate yield was significantly reduced. The citrate: lactoferrin molar ratio decreased from 1373 to 606. With oxytocin treatment, after 4 d milk yield first increased and then significantly decreased, citrate concentration decreased significantly while there were no significant changes in lactoferrin or BSA concentration or in the yield of any other milk constituents. The citrate: lactoferrin molar ratio decreased from 1621 to 1301. There were no significant changes in SCC either during treatment or 4 d after treatment but there was a significant rise at 16 d after treatment. It was concluded that in lactating cows both hormones affected citrate and lactoferrin concentrations in the direction that would improve the antibacterial properties of milk, but that this was accompanied by adverse effects on milk secretion. The extent of the change was not sufficient to be likely to produce inhibition of coliform bacteria.


Author(s):  
N. M. Kostomakhin ◽  
N. D. Ivanova

The results of research on the use of the feed additive “Ecostimul-2” and natural zeolite from the Khonguruu deposit in the Suntarsky district of the Republic of Sakha (Yakutia) in the rations of lactating cows have been presented in the article. The purpose of the work was to study the influence of feed additives “Ecostimul-2” and zeolite on the digestibility of nutrients and nitrogen metabolism in lactating cows of Kholmogorskaya breed under the conditions of Central Yakutia. Chemical analysis of feed, accounting of dairy productivity of cows has been carried out according to generally accepted methods. The cows of the control group have received the main ration. The cows of the experimental groups have been additionally received to the main ration: the 1st experimental feed additive “Ecostimul-2” in the amount of 200 mg/head/day, and the 2nd experimental group – “Ecostimul-2” in the amount of 200 mg/head/day and zeolite 200 g/head/day. The inclusion in the ration of lactating cows of Kholmogorskaya breed under the conditions of Central Yakutia of feed additives “Ecostimul-2” and zeolite of the Suntarsky deposit together has increased the digestibility of feed in the ration and improved the digestibility of nutrients and nitrogen metabolism. It has been found during the experiment that in cows have been receiving the feed additive “Ecostimul-2” and zeolite with the main ration (the 2nd experimental group) the average daily milk yield was 9,06 kg with a fat content of 3,8 % or was by 10,4 % higher than in the control group. In cows that have been received feed additive “Ecostimul-2” (the 1st experimental group) the average daily milk yield was 8,76 kg with the fat content of 3,77 % or was by 6,8 % more than in the control group.


Author(s):  
R. A. Maksimova ◽  
◽  
E. M. Ermolova ◽  
V. I. Kosilov ◽  
Yu. A. Karmatskikh ◽  
...  

Increasing the milk productivity of cows is the main task facing the livestock industry of our country. The study of some hematological and biochemical blood parameters in dairy cows when different feed additives are included in their rations is an urgent research task. The purpose of the investigations was to study the hematological and biochemical parameters of the blood of lactating cows when using different feed additives in the ration. During the investigations, the influence of feed additives such as Zaslon 2+ (at a dose of 20 g/head/day to the main ration), Diatomite (100 g/head/day to the main ration) and Monosporin (70 g/head/day to the main ration) on the hematological and biochemical blood parameters of lactating cows has been observed. The studied feed additives are used for the adsorption of mycotoxins in feed, normalization of digestive processes, and improvement of the livability and productivity of farm animals. In order to study the influence of the tested feed additives on the hematological parameters of the blood of lactating cows under the conditions of the Troitsky area in the Chelyabinsk region, on four groups of cows selected according to the principle of analogues (age, live weight, productivity, breed, physiological condition) the scientific and economic experiment has been carried out. As the result of the investigations, data have been obtained indicating that the feed additive Zaslon 2+ at the dose of 20 g/head/day has the greatest effect on the metabolism in the body of lactating cows.


Author(s):  
K. V. Kireeva ◽  
N. M. Kostomakhin ◽  
I. A. Pushkaryev ◽  
T. V. Kureninova

Primary changes in the physiological status of animals can be traced in the deviation from the norm of indicators of a number of substances in biological fl uids, since biochemical indicators are a kind of indicator of processes occurring in the body. Having knowledge of hematological changes in the body of cattle, managers and specialists of livestock farms can manage the productivity and health of highly productive animals. The purpose of the research was to determine and analyze the biochemical parameters of the blood of cows in the dry period and at the increasing the milk yield when wet crushed corn grain was introduced into their ration. The research has been carried out on cows of Black-and-White breed in LLC “Agrofi rma “Urozhai” in the Zonal district in the Altai Territory. During the research the prevalence of productivity indicators of cows of the experimental group over analogues from the control group was proved. Thus average daily milk yield for the accounting period (60 days) it was 30,9 kg, which was 5,2 kg more than the control herdmates (P > 0,95). The total productivity of one head was 1541,57 kg of milk in the control group and 1854,69 kg in the experimental group, which was 313,12 kg more (P > 0,95). It has been found that most of the studied biochemical parameters corresponded to the physiological norm. The exception was the increased content of total protein in the blood of lactating cows of the experimental group 5 g/l above the upper limit of the norm (P > 0,999). A low albumin content in the blood of animals of the experimental group has been noted, and this indicator was signifi cantly lower than that in the control group by 3,45 g/l (P > 0,99). An excess of the physiological norm of globulin in the blood of animals of both groups has been found, the indicators of the experimental group signifi cantly exceeded the control group by 9,5 g/l (P > 0,99). There was a low level of chlorides after the increasing the milk yield 88,1 mmol/l in the control group and 89,2 mmol/l in the experimental group, then excess of manganese after the increasing the milk yield was 4,50 mmol/l in the control group and 8,14 mmol/l in the experimental group, which could be associated with the increased content of this element in feed and soil.


Author(s):  
A. Farkhutdinova ◽  
M. Malikova

Among feed additives, probiotics used in animal husbandry are of great interest, containing live microorganisms that belong to the normal, physiologically justifi ed microfl ora of the intestinal tract and have a positive eff ect on the animal’s body. Newly created drugs (eff ective microorganisms – EM-drugs) are a set of microorganisms that have a benefi cial eff ect, clean all living things from pathogenic microfl ora and harmful chemical compounds. The purpose of the work was to establish the optimal doses of feeding the probiotic drug “Baikal EM 1” in the rations of dry and lactating cows in connection with the eff ectiveness of milk production. The researches have been carried out on cows of Black-and-White breed in the NE “Ufi mskoe” of the Bashkir Scientifi c and Research Institute of Agriculture, where the feed base and the condition of the production facilities met the veterinary requirements. The optimal dose and methods of application of the drug “Baikal EM 1” of probiotic action in the rations of cows in the Republic of Bashkortostan have been determined and tested. The positive infl uence of the probiotic drug on the processes of rumen digestion, digestibility and assimilation of nutrients, physiological and biochemical status, milk productivity, reproductive functions, the quality of the off spring and its livability has been established. The eff ect of using the drug “Baikal EM 1” in diff erent dosages on hematological parameters, digestibility and assimilation of nutrients, and nitrogen metabolism has been studied. The economic justifi cation of the use of the probiotic drug “Baikal EM 1” in the rations of cows has been given. It has been found that the most eff ective from the zootechnical, biological and economic points of view is to use the probiotic drug “Baikal EM 1” in the dose of 50 ml/head/day.


Author(s):  
Р.В. НЕКРАСОВ ◽  
А.С. АНИКИН

Рассмотрен вопрос расчета питательности адресных комбикормов для высокопродуктивных лактирующих коров в соответствии с современными нормами потребности в питательных веществах. В исследовании использована модель, разработанная в ФГБНУ ФНЦ ВИЖ им. Л.К. Эрнста, для расчета потребностей высокопродуктивных лактирующих коров в обменной энергии и питательных веществах с использованием факториального метода. В ней учтены показатели продуктивности (суточные удои), изменения живой массы, сроки стельности, упитанность, активность животных, МДЖ, МДБ в молоке на любой период лактации для высокопродуктивных лактирующих коров. В модели расчетов потребности лактирующих коров рассчитываются для рациона с одной составляющей, что не позволяет динамично изменять состав рациона в зависимости от периода лактации. Предложенная модель расчета построена на следующих принципах: рацион лактирующих коров состоит из двух составляющих (основная часть рациона и адресный комбикорм).Основная часть рациона обеспечивает от 5 до 15 кг молока в сутки. Продуктивность сверх данного уровня обеспечивается адресным комбикормом. Результаты расчета содержания энергии и питательных веществ для адресных комбикормов показаны на примере потребности в питательных веществах для молочных коров с удоем 8000 кг молока за лактацию (содержание в молоке жира — 3,8—4,0% и белка — 3,2%, живая масса взрослого животного — 600 кг, упитанность — 3,25 балла). The issue of calculating the nutritional value of targeted compound feeds for highly productive lactating cows in accordance with modern standards of nutrient requirements is considered. The study uses a model developed at the L.K. Ernst Federal Science Center for Animal Husbandry, for calculating the needs of highly productive lactating cows for metabolic energy and nutrients using the factorial method. The model for calculating the nutritional value of targeted compound feeds for high-yielding lactating cows takes into account productivity indicators (daily milk yield), changes in live weight, pregnancy terms, fatness, animal activity, % of fat and protein in milk for any lactation period for high-yielding lactating cows. In this calculation model, the needs of lactating cows are calculated for a diet with a single component, i.e. feed is included in the diet as a component of the concentrate part of the diet. This does not allow you to dynamically change the composition of the diet depending on the lactation period. The proposed calculation model is based on the following principles: the diet of lactating cows consists of two components (the main part of the diet and targeted feed). The main part of the diet provides from 5 to 15 kg of milk per day. Productivity above this level is provided by targeted feed. The results of calculating the energy and nutrient content for targeted compound feeds are shown by the example of the nutritional requirements for dairy cows with a milk yield of 8000 kg of milk per lactation (the content of fat in milk is 3.8—4.0% and protein is 3.2%, the live weight of an adult animal is 600 kg, body fatness is 3.25 points).


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 416-416
Author(s):  
Daria A Nikanova ◽  
Evgenia Kolodina ◽  
Olga Artemyeva ◽  
Yuri Fomichev

Abstract The transition period is the most stressful for dairy cows in terms of metabolic rate and characterized by dynamic changes in the hormonal profile, loss of appetite, negative energy balance, nutrient and vitamin deficiencies, compromised immunity and oxidative stress. The aim of the research was to balance the increase in cows’ productivity and the consumption of nutrients from the feed during the transition period through the use of energy feed additives (EFS), high protein feed concentrate (PFC) in combination with biologically active (BA) substances. Thirty-six dairy cows of black-motley breed were divided into 3 groups: (1) The main diet (G0, n = 12), not supplemented with additives, (2) additive 1 (G1; supplemented with 0.5 kg EFS / cow per day, n = 12), (3) additive 2 (G2; supplemented with 0.5 kg EFS; 0.5 kg PFC and 0.06 kg BA / cow per day, n = 12). The experimental part of the feeding lasted for 20 days before calving and the first 100 days after calving (DPP). Blood samples were collected during the first and the third months after calving. The biochemical analyzer was used to measure blood serum components. The milk yield was recorded monthly throughout lactation. BCS losses from 7 days prior to calving to 28 DPP were -0.29 for Gr2, -0.42 for Gr1 and -0.60 for Gr0. Feeding with additive 2 (Gr2) increased milk yield (p≤0.05) in the first 100 DPPs and (p≤0.001) 305 DPPs compared to G0. The number of samples with SCC ≥ 500 000 / ml. per 100 DPP was 51% in the Gr0 group, 27% in Gr1, 25% in Gr2. Also, microbiological control showed an excess of Bacterial cells in the milk of cows from group G0, which correlates with SCC indicators. Cows from Gr2had a lower content of ketone bodies (P≥0.001) and higher (P≥0.001) antioxidant activity of blood serum compared to Gr0. Cows from Gr2 had an increase in ALT activity by1.4 times (P <0.05) from the first to the third months after calving.


Author(s):  
M. V. Kharko ◽  
B. S. Denkovich ◽  
Y. I. Pivtorak ◽  
A. S. Naumyuk ◽  
R. A. Petryshak ◽  
...  

In recent years, a significant part of milk has been produced in farms of various organizational forms, mainly using feeds of their own production. At the same time, there are a number of problems, the solution of which affects the yield, quality and value of products, as well as future prospects in this industry. Scientific research has shown that the intensification of such an industry as dairy farming first of all depends on a strong forage base of the farm. In addition, lactating cows do not need generic feed, but a diet balanced in compliance with detailed rules. Their use makes it possible to increase milk yield by 20 and more percent. Therefore, when organizing a comprehensive feeding, it is necessary to take into account the features of protein, carbohydrate, lipid, mineral and vitamin nutrition. However, even a fully balanced ration does not guarantee the desired effectiveness. In this regard, a variety of feed additives of a natural substance, which also include supplements with probiotic action, deserve a special attention in the system of nutrition. One of these is the Biosprint microbial additive, which contains living yeast cultures (Saccharomyces cerevisiae, MUCL strain, 39885) and belongs to the group of biotic additives. This research is based on the need for the optimization of the limited feeding of milk cows through the use of the Biosprint feed additive in addition to a semi-concentrated type of feeding. Based on the conducted test use (90 days), it is necessary to determine the additive’s effect on the rumen digestion processes, milk yield and qualitative indicators of milk and to determine its optimal content in the diet. It was established that feeding the Biosprint additive as part of the diet contributed to the improvement of the intensity of metabolic processes in cows, in particular, in the rumen. The assumed growth of the number of amylo- and cellulolytic and proteolytic bacteria was detected, which contributed to their enzyme activity and, in turn, led to an intensive hydrolysis of carbohydrate feeds, as a result of which an assumed growth of VFAs as milk fat precursors occurred. Positive results were obtained in terms of the value of milk yield of cows in study groups in comparison with the control group across average daily milk yield by 1.2–2 kg, which constitutes a growth of 5.5–9.2%.There was a stable tendency towards an increase of fat content in milk by 0.05–0.1% and protein by 0.02–0.03%, which indicates an improvement in milk quality. Summing up, conducted study focused on the evaluation of the productive effect of the Biosprint drug on the milk yield of cows and the qualitative indicators of milk make a case for the expediency of the use of the above in the diet structure when feeding milk cows.


Author(s):  
S. Sukhanova ◽  
G. Uskov ◽  
T. Leshchuk ◽  
N. Pozdnyakova ◽  
V. Yaroslavtsev ◽  
...  

Scientists of the Kurgan State Agricultural Academy named after T. S. Maltsev conduct research on the development of diff erent feed additives and compound feeds, their use in feeding animals and poultry. It has been developed mineral additives, which used mineral components to meet the needs of macro- and microelements of cows during lactation. The purpose of the work was to solve the problem of lack of minerals in animal husbandry by preparing granular feed additives based on raw materials of domestic production, enriched with trace element salts. Feeding of experimental mineral additives positively aff ected the average daily milk yield already in the 1st month of lactation. Thus, in the 1st experimental group more milk has been obtained by 0.6 % and in the 2nd group by 1.9 % compared to the control one. In the 2nd month of lactation milk yield in the 1st experimental group was greater by 2.3 %, and in the 2nd experimental group – 4.0 % compared to the control group. The same trend has been observed in the following months: in the 3rd month of lactation the diff erence in milk yield compared to the control group was in the 1st experimental group 4.0 %, in the 2nd experimental group – 6.5 %, in the 4th month, respectively, 5.7 and 9.3 %. Milk yield for 120 days of lactation in cows of the control group was 2951.4 kg of milk (in terms of 4 % fat content) in the 1st experimental group more by 3.4 %, and in the 2nd experimental group by 6.2 %. The fat content in the milk of cows of the experimental groups was higher by 0.03 and 0.04 abs.%, and protein by 0.02 and 0.03 abs.%, respectively. In this regard, the sale price of 1 kg of milk has changed. In the control group it amounted to 21,48 rubles, in the 1st experimental group more by 0,7 %, and in the 2nd group by 1,0 %. This led to an increase in the profi tability of milk production: in the 1st experimental group by 4,5 %, and in the 2nd experimental group by 6,8 %. Consequently, the feeding of new mineral additives allowed to reduce the prime-cost of milk, increase milk productivity of cows and profi tability of milk production.


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