scholarly journals The concordance of endoscopic and histologic findings of 530 pediatric patients suspicious for celiac disease in a referral center, Isfahan, Iran

2020 ◽  
Vol 5 (2) ◽  
pp. e27-e27
Author(s):  
Azar Naimi ◽  
Azar Baradaran ◽  
Elahe Pirpiran ◽  
Peiman Nasri ◽  
Masoud Akhlaghi

Introduction: The purpose of this study is evaluation of concordance of histologic and endoscopic findings in pediatrics referred to Imam Hossein children’s hospital, in Isfahan for evaluation of celiac disease. An accurate prediction of the likelihood of a histologic finding in the setting of a visually normal endoscopy can help prepare families for unanticipated results. Patients and Methods: This is a retrospective study conducted from 2015-2017. The sampling method is census and all eligible patients are included in the study. At the beginning of the work, obtaining consent for entering the project has been done through interviews. After that, patients information such as file number, age and gender according to the file were entered into the data gathering sheet. Data were analyzed using SPSS software version 22. Pvalue< 0.05 was considered significant. Results: Around 530 patients suspected of having celiac disease participated in the present study. The mean age of the subjects was 6.88 ± 4.31 years. Among them, 57.6% (305 patients) were girls and 42.4% (225 patients) were boys. According to the results, the kappa agreement coefficient is equal to 0.42. There was moderate agreement between endoscopy and pathology findings (kappa = 0.42). Conclusion: The results of the study and the kappa Cohen coefficient indicate the appropriateness of using endoscopy in patients with suspected celiac disease.

2019 ◽  
Vol 17 ◽  
pp. 205873921985557
Author(s):  
Maria Giulia Berioli ◽  
Giulia Mancini ◽  
Nicola Principi ◽  
Elisa Santi ◽  
Martina Ascenzi ◽  
...  

To compare growth and glycemic control in children with type 1 diabetes and silent celiac disease treated with a gluten-free diet for 1 year with those of similar age and gender with type 1 diabetes but without celiac disease, 16 type 1 diabetes patients with silent celiac disease were enrolled and each celiac disease-positive case was matched for age, sex, and duration of diabetes with two type 1 diabetes controls with negative serologic markers of celiac disease. All 16 children with positive celiac disease serology had histologic features consistent with celiac disease despite the absence of symptoms. The mean growth and metabolic control values were similar between children with type 1 diabetes and celiac disease and those with type 1 diabetes but without celiac disease. This study seems to suggest that the early diagnosis of celiac disease and initiation of a gluten-free diet may prevent further deterioration in the nutritional status of children with type 1 diabetes and celiac disease and may reduce the prospect of celiac disease complications without any impact on type 1 diabetes control.


2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S350-S351 ◽  
Author(s):  
Recep Tekin ◽  
Fesih Aktar ◽  
Celal Ayaz

Abstract Background Brucellosis is still endemic in many developing countries and frequently leads to misdiagnosis and treatment delays. Indirect inflammatory markers such as mean platelet volume (MPV), platelet distribution width (PDW), red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been identified as markers of inflammation. The present study aimed to evaluate and compare the levels of these markers for prognostic purposes, and to assess the correlation of C-reactive protein (CRP) with brucellosis in adults and children. Methods The study included 137 adults and 141 age- and gender-matched healthy controls, as well 71 children and 81 age- and gender-matched healthy controls. Hematological parameters and CRP were retrospectively recorded and compared between the adult and pediatric patients. Results The mean age of the adult patients (54% female) was 43.1 ± 15.4 years, whereas the mean age of the pediatric patients (50.7% male) was 9.5 ± 3.6 years. Significantly higher lymphocyte count, and lower neutrophil count, platelet count, RDW, MPV, NLR and PLR values were found in adult brucellosis patients compared with their healthy subjects, whereas higher lymphocyte count, PDW and lower neutrophil count, platelet count, MPV, NLR and PLR values were observed in pediatric brucellosis patients compared with the control subjects. Significantly higher neutrophil count (p=0.019) and NLR (p&lt;0.001) were found in adult patients compared with the pediatric patients. Positive correlation was found between CRP and NLR (R2 = 0.052, P = 0.011), PLR (R2 = 0.061, P = 0.006) in adult patients. Conclusion Based on our findings, we consider that the use of complementary indirect markers such as MPV, NLR, PLR and RDW together with the CRP test – which is used concomitantly with serological diagnostic tests in situations where brucellosis is suspected – might be helpful in the diagnosis and follow-up of brucellosis, as well as in the evaluation of complications and response to therapy, in both adult and pediatric brucellosis patients. Disclosures All authors: No reported disclosures.


2020 ◽  
Vol 11 ◽  
pp. 215145932098539
Author(s):  
Anil Taskesen ◽  
Ali Göçer ◽  
Kadir Uzel ◽  
Yüksel Uğur Yaradılmış

Introduction: Proximal humerus fractures (PHF) constitute the majority of the most common osteoporotic fractures. Bone density measurements can affect treatment methods and outcomes. This study was aimed to investigate the effect of osteoporosis values, measured from direct radiographs, on fracture type, surgical outcomes. Methods: 248 patients over 50 years of age who presented to Mersin City Hospital between 2017 and 2020 with proximal humeral fractures were retrospectively evaluated. The age and gender of the patients and the fracture types were evaluated according to the AO classification system from the direct radiographs obtained at the time of admission were recorded. The Tingart cortical thickness and deltoid tuberosity index (DTI) measurements were used to assess osteoporosis status in all patients. Postoperative and follow-up radiographs of 45 patients, treated with fixed-angle proximal humeral locking plate, were evaluated for radiographic results and their correlations with osteoporosis measurements were examined. Results: According to the demographic characteristics of the patients, 171 patients were female and 77 patients were male (F/M: 3/1), and mean age was 69.2 ± 11.66 (50-95). Considering the bone quality parameters in all patients, the mean Tingart value was 5.8 ± 1.6 mm and the mean DTI was 1.43 ± 0.17, where there was a correlation between the Tingart value and DTI (r = 0.810 and p < 0.001). Although there was a statistically significant relationship between the osteoporosis parameters and age and gender (p < 0.001 and p = 0.023, respectively), main AO fracture types were not related to osteoporosis (p < 0.05). In the operated group (n = 48, 19%), 19 patients (42%) showed poor outcomes, which were not associated with age and osteoporosis parameters. Conclusion: This study was concluded that osteoporosis parameters differ between genders and age groups in patients with PHF, however osteoporosis is not the main factor affecting the fracture type and surgical outcomes.


2021 ◽  
Vol 15 (12) ◽  
pp. 3198-3199
Author(s):  
Pervez Muhammad ◽  
Sajjad Muhammad ◽  
Muhammad Tariq ◽  
Amir Khan ◽  
Akhtar Munir ◽  
...  

Aim: Prevalence of colorectal carcinoma with respect to age and gender Study design: Observational / cross sectional study. Place and duration of study: This study was conducted at the Department of Pathology and Surgery, Post Graduate Medical Institute Lahore and Jinnah Medical College Peshawar from July, 2013 to February, 2015 Methodology: Surgical specimens of 60 histopathologically diagnosed cases of colorectal adenocarcinoma were included in this study. Age and sex were evaluated in CRC. Results: The mean±sd of age was 54.4±19.7 yrs. Out of 60 cases, 6 (10%) were between 16-29 yrs, 9 (15%) cases were between 30-49 yrs, 34 cases (56.7%) were of 50-69 yrs and 11 cases (18.33%) were of 70 yrs. Out of sixty cases, males were 33 (55%) and females were 27(45%). Conclusion: There are 34 out of 60(56.7%) patients were 50-69 years and 33 out of 60 (55%) cases were males i.e. males dominance. Keywords: Colorectal adenocarcinoma, immunohistochemistry, gender


2017 ◽  
Vol 6 (1) ◽  
pp. 54
Author(s):  
Muwafaq Mohammed Alkubaisi

This paper provides a list of good practice in the conduct and reporting of survey research. Its purpose is to assist the trainee researcher to produce survey work to a high standard level. The research paper provides a scope of the methodology used showing the processes of data gathering tools & field procedures for each population of interest(citizens, residents, and tourists), data analysis, and some sample size issues. The research is not meant to provide a manual of how to conduct a survey, but rather to identify common difficulties and errors to be avoided by researchers if their work is to be efficient and sound.The paper has shown the approaches for Assessing Customer Satisfaction and the main outcome of this experience in judging whether the survey questions flow: logic, order, relevance, easily understood, adequate to be measured.Sampling plan used in this research suggested that the sample is a national probability sample drawn proportionate to the population by age and gender, and separately by the municipality. These groups are used as sampling parameters that have provided the number of sub-groups to be investigated. In this survey, there were two sources of under-coverage and over-coverage in the sample design. First, some residents live in labor gatherings. Second, there was the challenge of having to over-sample citizens in individual municipalities. Each of these issues examined and dealt with accordingly.


2012 ◽  
Vol 3 (2) ◽  
pp. 126-130 ◽  
Author(s):  
Sangeetha Ramu ◽  
Charlotte Rodrigues

ABSTRACT Objectives The purpose of the study was to analyze the frequency and distribution of gingival lesions in MR Ambedkar Dental College, Bengaluru. Materials and methods The material included the biopsies of all localized reactive hyperplastic lesions (LRHL) of the gingiva stored in the department's database (1995-2011). The lesions were analyzed according to their location and the patient's age and gender. The findings were compared with other published studies on reactive lesions. Results A total of 260 reactive lesion biopsies were accessed. focal fibrous hyperplasia (FFH) was the most common (38.5%), followed by pyogenic granuloma (PG) (34.6%), peripheral ossifying fibroma (POF) (17.7%) and peripheral giant cell granuloma (PGCG) (9.2%). The mean age of the patients was 33 years, with a range varying from 9 to 80 years. The LRHL occurred more commonly in females except focal fibrous hyperplasia, which showed male predilection. PG and POF were more common in the maxilla and FFH as well as PGCG were more common in the mandible. Conclusion This study indicates some differences in age and gender distribution as well as in location between the different lesions. The results of this study differ from those of other studies and the data presented here can be used as a guide for further multicenter studies. How to cite this article Ramu S, Rodrigues C. Reactive Hyperplastic Lesions of the Gingiva: A Retrospective Study of 260 Cases. World J Dent 2012;3(2):126-130.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Dilhan İlgüy ◽  
Mehmet İlgüy ◽  
Erdoğan Fişekçioğlu ◽  
Semanur Dölekoğlu ◽  
Nilüfer Ersan

Aim. The aim of the present study was to examine the relationship between articular eminence inclination, height, and thickness of the roof of the glenoid fossa (RGF) according to age and gender and to assess condyle morphology including incidental findings of osseous characteristics associated with osteoarthritis (OA) of the temporomandibular joint (TMJ) using cone beam computed tomography (CBCT).Materials and Methods. CBCT images of 105 patients were evaluated retrospectively. For articular eminence inclination and height, axial views on which the condylar processes were seen with their widest mediolateral extent being used as a reference view for secondary reconstruction. Condyle morphology was categorized both in the sagittal and coronal plane.Results. The mean values of eminence inclination and height of males were higher than those of females (P<0.05). There were significant differences in the RGF thickness in relation to sagittal condyle morphology. Among the group of OA, the mean value of the RGF thickness for “OA-osteophyte” group was the highest (1.59 mm), whereas the lowest RGF values were seen in the “OA-flattening.”Conclusion. The sagittal osteoarthritic changes may have an effect on RGF thickness by mechanical stimulation and changed stress distribution. Gender has a significant effect on eminence height (Eh) and inclination.


1991 ◽  
Vol 107 (2) ◽  
pp. 453-463 ◽  
Author(s):  
S. Sabesan ◽  
K. Krishnamoorthy ◽  
K. N. Panicker ◽  
P. Vanamail

SUMMARYRates of acquisition and loss of Brugia malayi microfilaraemia were estimated using the parasitological data of a cohort of population in Shertallai, South India. The rate of acquisition of microfilaraemia was found to be dependent on age but not gender. The decline in the rate of acquisition of microfilaraemia in adults above 35 years could be due to the development of acquired immunity. The mean reproductive lifespan for the periodic Brugia malayi adult female worm was estimated to be 34 years and it was independent of host age and gender. The age-specific estimated proportion of population at risk (microfilaria carriers who lost their microfilaria in course of time) of developing lymphoedema approximately mirrored the observed age specific prevalence of lymphoedema in the study-population. On an average, 99% of population at risk developed manifestations of disease. The estimated population at risk of developing disease in different endemic areas is compared and its epidemiological significance is discussed.


2003 ◽  
Vol 27 (1) ◽  
pp. 91-94 ◽  
Author(s):  
Ali Mentes ◽  
Julide Atukeren

The aim of the study was to evaluate toothbrushing management and ability of children in relation to age and gender. The study population consisted of 75 children and were divided into three equal groups as 3-5, 6-8 and 9-11 years of age.The grip type during toothbrushing was recorded on videotape.The most preferred grip types were distal (73%) followed by power (43%) and oblique grips (29%). There were a statistically significant differences between age groups and the grip types (p&lt;0.001) but no significant difference was seen between boys and girls in grip preferences (p&gt;0.05).The mean duration of toothbrushing was shorter in 3-5 years of age group (28 seconds) than the 6-8 and 9-11 age groups (35 and 47 seconds respectively).


Author(s):  
Watfa Al-Mamari ◽  
Ahmed Babiker Idris ◽  
Ahlam Ali ◽  
Saquib Jalees ◽  
Muna Al-Jabri ◽  
...  

Objective: Intelligence profile with age and gender differentials analysis and identification of a battery of subscales of intelligence are important for clinical management of ASD problems among children as well as in facilitating placement for remedial and educational services. Hence, this study aims to explore the intelligence quotient (IQ) profile among children with ASD and identify the most important subscales that predict the IQ. Method: The study is based on data collected through an exploratory study of 100 children aged between 3 and 13 years, who were referred to the department of child health and development in a tertiary hospital in Oman between June 2016 - June 2019. Results: Among the participants of this study, 79% were males, resulting in a male: female ratio of 4:1. The mean of full-scale IQ was found to be 68.58±18. The mean of non-verbal IQ (73.5±17.5) was significantly higher than the mean of verbal IQ (65.46±17.6). More than half (61%) of the children were observed to have mild to moderate impairment in IQ level. Conclusion: Age and gender showed no significant association with intelligence level. Regression analysis identified non-verbal fluid reasoning, non-verbal visual-spatial processing, non-verbal working memory and verbal knowledge as the significant predictors of total IQ. The significant dimensions of verbal and non-verbal IQ identified in this study can be used to evaluate difficult cases.   Keywords: Autism, Oman, Intellectual profile, prediction 


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