scholarly journals Aktivitas Larvasidal Ekstrak Etanol Biji Pepaya (Carica papaya) dan Daun Mindi (Mella Azedarach)

2019 ◽  
Vol 7 (1) ◽  
pp. 53-61
Author(s):  
Agus Saputra ◽  
Dewi Fesbayati Lestari Djungu ◽  
Emerlinda P. Gelalan

Helminthiasis is an adverse disease. This disease is caused by parasites such as trematodes, cestodes, and nematodes. The search for bioactive compounds from various plants that have anthelmintic activity is carried out by various researchers. Papaya seeds and mindi leaf have been known as a good plants for health. Various studies shown that extracts water, ethanol and chloroform have activity for antimicrobial, antilipidemia, antidiabetic and antiparasitic. In this study the extraction of secondary metabolites from mindi leaf and papaya seeds was carried out for larvicidal activity. From the results of extraction with ethanol, the yields of mindi leaf and papaya seeds were obtained 19.97% and 12.97% respectively. Phytochemical analysis shows that both extracts have the same class of compounds tannins, saponins, phenolhydroquinones, flavonoids, and alkaloids. The difference is in the concentration of tannin and saponin mindi leaf higher than papaya seeds. In testing larvicidal activity, the extract of mindi leaf had a stronger activity compared to papaya seeds. Extract mindi leaf 15% has the strongest activity of killing larvae at ± 25 minutes. This activity is stronger than extract papaya seed 15% which is ± 125 minutes or with albendazole 0.03%, ± 46 minutes

2019 ◽  
Vol 4 (1) ◽  
pp. 7-10
Author(s):  
Ninik Mas Ulfa ◽  
Galuh Gondo Kusumo ◽  
Ilil Maidatuz Zulfa

ABSTRAKTumbuhan pepaya (carica papaya L) merupakan tumbuhan tropis yang banyak terdapat di Indonesia. Tumbuhan ini mempunyai banyak manfaatnya mulai dari buah, biji, hingga daunnya. Penelitian pendahuluan menyebutkan buah pepaya mengandung alkaloid dan flavonoid yang berkhasiat sebagai antikanker. Senyawa BenzylIsothiocyanat diketahui banyak terdapat pada biji dan buah pepaya yang sudah matang. Kandungan BenzylIsothiocyanat mempunyai khasiat sebagai antikanker. Pemanfaatan limbah biji pepaya pada penelitian ini untuk membuktikan aktivitas Benzyl-Isothiacyanat yang berkhasiat sebagai antikanker. Penelitian ini merupakan penelitian pendahuluan untuk menganalisis aktivitas antikanker dari Ekstrak kental biji pepaya dengan menggunakan metode BSLT. Konsentrasi ekstrak kentak yang digunakan yaitu 100 ppm, 200 ppm dan 300 ppm masing-masing diujikan pada 10 larva udang dalam air laut. Diperoleh hasil rata-rata kematian pada konsentrasi 100 ppm adalah 4,3, 200 ppm adalah 5,3 dan 300 ppm adalah 6,7. Hasil regresi linearitas menunjukkan aktivitas antikaker pada uji BSLT dari Ekstrak kental biji pepaya dengan LC50 sebesar 163,89 ppm. Dengan demikian ekstrak kental biji pepaya tersebut berpotensi untuk dikembangkan sebagai bahan antikanker alamiKata kunci: Aktivitas antikanker, Carica papaya, metode BSLT.ABSTRACTPapaya plant (carica papaya L) is a tropical plant that is widely found in Indonesian. This plant has many benefits ranging from fruit, seeds, to leaves. Preliminary research says papaya fruit contains alkaloids andflavonoids which are efficacious as anticancer. Benzyl-Isothiocyanat compounds are known to be widely found in ripe papaya seeds and fruit. The content of Benzyl-Isothiocyanat has properties as an anticancer. The use of papaya seed waste in this study is to prove the activity of Benzyl-Isothiacyanat which is efficacious as an anticancer. This research is a preliminary study to analyze the anticancer activity of thick papaya seeds using the BSLT method. The concentrations of used fart extracts were 100 ppm, 200 ppm and 300 ppm each tested on 10 shrimp larvae in seawater. The results of the average mortality at concentrations of 100 ppm were 4.3, 200 ppm were 5.3 and 300 ppm was 6.7. The linearity regression results showed the anticaker activity in the BSLT test from the thick extract of papaya seeds with LC50 of 163.89 ppm. Thus the thick extract of papaya seeds has the potential to be developed as a natural anticancer material.Key Words : Anticancer activity, BSLT method, Carica papaya.


Author(s):  
Purushothaman M ◽  
Soujanya H ◽  
Jagadeeshwari S ◽  
Shiva Kumar K

To advance new proof about the counter ripeness action of seeds concentrate of papaya (Carica papaya L.) in test creatures, particularly mice. Male mice (n=20) were assembled into four. The principal bunch got just purified water containing 1% CMC as the controller. Gathering 2, 3 and 4 sequentially got papaya seed concentrate of 2, 4 and 8mg/40 g body weight. All conduct regulated verbally utilizing abdominal sonde once every day for 35 days. Revision boundaries surveyed cell checks, the distance across and epithelial chunkiness of seminiferous tubules of the testis. Even though the aftereffects of exploration on the antifertility action of papaya seed separate demonstrated an optimistic pattern, yet in-depth confirmation impacts plant arrangements on investigation animals is obligatory suggested World Health Organization. This examination is proposed to advance novel proof counter fruitfulness movement of papaya seed removes in guinea pigs, particularly mice. There is no substantial diverse in the number of spermatogonia among treatment gatherings: spermatocyte and spermatid cells fundamentally diminished by the excerpt, particularly at the most elevated portion. Moreover, the breadth and epithelial thickness of seminiferous tubules of testis are significantly decreased by the concentrate at the portion of 8 mg/40g body weight. Papaya seeds separate as possible to be utilized as against ripeness operator.


2020 ◽  
Vol 9 (1) ◽  
pp. 77
Author(s):  
Azhari Azhari ◽  
Nilva Mutia ◽  
Ishak Ishak

Papaya is the most beneficial fruit for human health. In addition to the fruit that can be consumed, it turns out papaya seeds can also be used. In addition to the seeds used to be planted as well as only being waste, oil can also be obtained from papaya seeds. One method for obtaining papaya seed oil is a method of extracting heat (requires installation in the process), in general the notion of reflux is extraction with a solvent at its boiling temperature point, for a certain time and the amount of solvent adjusted to air temperature. In this research, papaya seed extraction was carried out, percent yield analysis was carried out, and heavy type analysis of papaya seed oil extraction was carried out. The purpose of this study was to study the variation in extraction time of papaya seeds with solvents on the yield of oil produced. This research was carried out by reacting papaya seeds with hexane solvents at 65 ℃. Where the weight of papaya seeds is 50 gr, and the volume of solvents varied by 300 ml, 400 ml, and 500 ml and the reaction time is 120 minutes, 150 minutes, and 180 minutes. The results showed that the largest papaya seed oil was 34.2% at a volume of 500 ml solvent for 180 minutes and a high density of 0.87 gr / ml at a volume of 500 ml solvent for 180 minutes.Keywords: Extraction, hexane, papaya seed oil, reflux


2021 ◽  
Vol 12 (6) ◽  
pp. 7787-7795

Natural coagulants are proven to be a good alternative to conventional coagulants with the removal of various pollutants and are environmentally friendly. Despite its advantages, the least studies were carried out on local agro-wastes such as papaya seeds as natural coagulants concerning different operational factors. The study analyzes the main and interactions effect between the coagulant dosage, initial turbidity, and pH on deshelled Carica papaya seeds for turbid water treatment. A 2-level factorial design was used to investigate the main and interaction effects of the main operational factors, viz. coagulant dosage (50-200 mg/L), pH (3-7), and initial turbidity (100-500 NTU) on the turbidity removal of the synthetic turbid water. Based on individual performance, the results suggested that initial turbidity and pH are the most significant factors among the investigated operational factors. In combination, all interactions are significant, but the interaction between initial turbidity and pH is most significant, with 97.2% turbidity removal. Upon application of Carica papaya seed as a natural coagulant in water and wastewater treatment, these operating variables and their interactions are best to be considered.


Author(s):  
V. H. A. Enemor ◽  
O. F. Nworji ◽  
U. C. Ogbodo ◽  
O. R. Ngwu ◽  
E. C. Orji ◽  
...  

Papaya seeds, though rarely eaten, are used in folk medicine around the world. This study analysed the seeds to evaluate their nutritional and phytochemical content using standard methods. Proximate analysis showed the seeds are a good source of carbohydrate (48.91% ± 0.69) and protein (24.33% ± 0.74). Essential minerals such as iron (70.16 mg/kg ± 0.08), selenium (12.50 mg/kg ± 0.08), and calcium (26.96 mg/kg ± 0.08) are present in the seeds at optimal quantities. Amino acid and vitamin analysis indicated that papaya seeds are rich sources of vitamin A (117.28 ± 2.09 mg/kg), B6 (37.70 ± 1.84 mg/kg), D (27.60 ± 3.96 mg/kg), K (119.81 ± 15.88 mg/kg), and all essential amino acids. Phytochemical analysis of the seeds revealed forty-three bioactive compounds including acetic acid and pyrrole, both of which have antimicrobial properties. From the above analytical results, it was revealed that papaya seeds have nutraceutical properties and can be used, in the appropriate quantity as a food or health supplement or an adjunct animal feed.


Author(s):  
Archita Behera ◽  
Rajkumari Supriya Devi ◽  
Srimay Pradhan ◽  
Somali Biswal ◽  
Padan Kumar Jena ◽  
...  

Costus speciosus L. is a tuberous plant commonly available in wetlands and near water bodies throughout Odisha state and used as food and medicinal purposes. The tribal communities of the state used the rhizome to cure joint pain, skin infections and consume as nutraceutical. The above claims are supportive of the fact that the rhizome might have antioxidant potentials and might be rich with diverse secondary metabolites. Keeping this in view an attempt has been made to evaluate the bioactive compounds present in the plant parts and antioxidant potentials in order to validate the tribal claims. Results revealed that the plant parts are rich with phenolic compounds and have antioxidant potential.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rajani KS ◽  
Swasha Khandeparker Naik ◽  
Subhadarshini Satapathy ◽  
Sweta Mishra

The present study highlights preliminary phytochemical analysis of the leaf extract of Nyctanthes arbor-tristis. Plants produce a wide range of bioactive molecules which make them as a rich source of various types of medicines. Nyctanthes arbor-tristis is one of the well-known medicinal herbs of Indian origin belonging to family Oleaceae, commonly known as night Jasmine. The leaf extract is taken by percolation method. Various bioactive primary and secondary metabolites were tested using colour reactions with specific reagents. The study reveals that it contains some bioactive compounds which indicate that this plant might be used as anti-malarial, anti-viral and antidiabetic.


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