scholarly journals Pengaruh Ekstrak Daun Pedada (Sonneratia caseolaris) Sebagai Antihiperkolesterolmia Pada Mencit (Mus musculus)

bionature ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ramlah Ramlah
Keyword(s):  
Total Cholesterol ◽  
Mus Musculus ◽  
Methanol Extract ◽  
Methyl Cellulose ◽  
High Cholesterol ◽  
Sonneratia Caseolaris ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Carboxy Methyl

Abstract. This study was conducted to determine the effect of extract leaf pedada (Sonneratia caseolaris) to total cholesterol levels of mice (Mus musculus) male ICR strain. Leaf pedada extracted using 96% methanol by maceration. This study is a completely randomized design (CRD), which consists of 5 treatments and 5 replicates the normal group (distilled water), positive group (Simvastatin), a group of leaf pedada extract at a dose of 125, 250 and 500 mg / kg. The extract was dissolved using Carboxy Methyl Cellulose (CMC) 0.5% and given orally in mice which had previously been given a high cholesterol feed. The results showed the methanol extract of leaves cemba with the dose of 500 mg/kg hads the highest effectiveness in lowering total cholesterol levels in mice which have hypercholesterolemia with a 30,20 % percentage drop. These results indicate that of the giving leaf extract pedada (Sonneratia caseolaris) able to lower total cholesterol levels of mice (Mus musculus) male hypercholesterolaemia.Keywords: Antihipercholesterolemia, total cholesterol, Methanol extract of  leaf pedada (Sonneratia caseolaris), mice (Mus musculus) ICR male.

scholarly journals Pengaruh Perbandingan Jenis Buah (Terong Belanda Dan Bit) dan Konsentrasi Carboxy Methyl Cellulose (CMC) Terhadap Mutu Organoleptik Sorbet

2016 ◽  
Vol 1 (1) ◽  
pp. 941-946
Author(s):  
Nanda Supriana ◽  
Dian Hasni ◽  
Syarifah Rohaya
Keyword(s):  
Concentration Factor ◽  
Methyl Cellulose ◽  
The Other ◽  
Carboxy Methyl Cellulose ◽  
Sour Taste ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Betalain Pigment ◽  
Carboxy Methyl

Abstrak.  Terong belanda merupakan buah berasa asam yang khas, namun memiliki warna yang kurang menarik. Disisi lain buah  bit mempunyai warna yang menarik, karena pada buah bit terkandung pigmen betalain yang dapat menghasilkan warna merah dan ungu. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh konsentrasi CMC dan penambahan buah terong belanda dan bit terhadap mutu organoleptik sorbet. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan faktor perbandingan buah terong belanda dan bit (P1 = 1:1, P2 = 2:1 dan P3 = 3:1) dan konsentrasi CMC ( C1 = 0%, C2 = 0,25%,  C3 = 0,50 % dan C4 = 75 %) dengan total  24 satuan percobaan. Hasil analisis menunjukkan penambahan proporsi terong belanda cenderung meningkatkan nilai organoleptik aroma dan rasa, sedangkan peningkatan konsentrasi CMC cenderung meningkatkan nilai organoleptik warna, rasa dan tekstur. Sorbet dengan perlakuan terbaik berdasarkan analisis keseluruhan diperoleh dengan menggunakan buah terong belanda:bit(2:1) dengan respon uji hedonik untuk warna 4,53 (agak suka), aroma 4,23 (netral), rasa 4,40 (agak suka) dan tekstur 4,63 (agak suka). Abstract. Terong belanda is a sour-taste typical fruit, but it has a less attractive color. On the other hand, beetroot has an interesting color because it contains betalain pigment producing red and purple colors. The purpose of this study was to determine the effect of CMC concentration and the addition of terong belanda and beetroot on the organoleptic quality of sorbet. This study used a Completely Randomized Design (CRD) with the ratio of terong belanda and beetroot factor (P1 = 1:1, P2 = 2:1 and P3 = 3:1) and CMC concentration factor (C1 = 0%, C2 = 0.25 %, C3 = 0.50% and C4 = 75%) with two replicates creating a total of 24 experimental units. The results showed that the addition of terong belanda tended to increase the proportion of aroma and taste organoleptic values, while the increase in the concentration of CMC tended to improve the color, taste and texture organoleptic values. The best Sorbet was obtained using the ratio of terong belanda and beetroot (2:1) having the following hedonic characteristics: 4.53 (a bit like) color, 4.23 (neutral) aroma, 4.40 (rather like) flavor and 4.63 (a bit like) texture.

scholarly journals The effect of feeding fermented kombucha tea on HLD, LDL and total cholesterol levels in the duck bloods

2011 ◽  
Vol 27 (4) ◽  
pp. 1749-1755 ◽  
Author(s):  
L. Adriani ◽  
N. Mayasari ◽  
A Angga ◽  
R. Kartasudjana
Keyword(s):  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Animal Husbandry ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Kombucha Tea ◽  
Completely Randomized Design ◽  
Different Levels ◽  
Effect Of Feeding

Kombucha have high content of glucoronic acid, a substance that could neutralized cholesterol deposit, changed to another compound that more soluble in water. The experiment concerns the effects of supplementary fermented kombucha tea on HDL, LDL, and total cholesterol levels in the duck bloods. It was carried out at the Faculty of Animal Husbandry, Universitas Padjadjaran. The objective of this research was to determine the effect of giving different levels of fermented kombucha tea on High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL) and the total cholesterol levels of duck bloods. This research used an experimental methods with completely randomized design (CRD). There were five treatments (P0 = 0%, P1 = 10%, P2 = 15%, P3 = 20%, and P4 = 25%) and four replications. Results indicated that all treatment decreased significantly LDL and total cholesterol levels, and increased HDL. The conclusion is, the addition of fermented kombucha tea up to 25% will decrease LDL and total cholesterol, and increase HDL in the duct blood.

scholarly journals LIPID PROFILE OF MALE LOCAL RABBIT (Lepus sp.) THAT GIVEN COMMERCIAL FEED SUPPLEMENTED BY COD LIVER OIL

2018 ◽  
Vol 22 (1) ◽  
pp. 7
Author(s):  
NI GUSTI AYU MANIK ERMAYANTI ◽  
I GUSTI LANANG OKA ◽  
I GEDE MAHARDIKA ◽  
PUTU SUYADNYA
Keyword(s):  
Fatty Acid ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cod Liver Oil ◽  
Feed Supplementation ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Commercial Feed ◽  
Completely Randomized Design ◽  
Different Levels

ABSTRACT   Cod liver oil as a source PUFA (Polyunsaturated Fatty Acid) has very diverse and complex benefits, including for heart health. This study aimed to improve the lipid profile of male local rabbit which was fed commercial supplementation of cod liver oil. The experimental design used was Completely Randomized Design (RAL) with four feed treatments, ie commercial feed without supplementation of cod liver oil (P0) as control, commercial feed supplemented by cod liver oil 1.5% (P1), commercial feed supplemented by oil liver of 3% cod (P2) and commercial feed supplementation of cod liver oil 4.5% (P3).Each treatment consists of eight rabbits. The variables observed were total cholesterol, triglyceride, LDL, and HDL levels. The data obtained were analyzed with ANOVA and if significantly different were tested further with DMRT. The results showed that supplementation of cod liver oil with different levels in commercial feed showed significantly different results (P <0.05) on total cholesterol, triglyceride, LDL, and HDL levels of local rabbit. It can be concluded that supplementation of cod liver oil in commercial feed to the extent 4.5% capable repair the lipid profile of male local rabbit because it can decreased  total cholesterol levels, decrease triglycerides levels, decreased LDL levels, and increased HDL levels.

scholarly journals The Effect of CMC Addition on the Characteristics of Sweet Potato (Ipomoea Batatas L. Cv Cilembu) Velva

2017 ◽  
Vol 2 (6) ◽  
pp. 680
Author(s):  
Mohamad Djali ◽  
Maulisa Firbiani ◽  
Marsetio Marsetio
Keyword(s):  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Economic Value ◽  
Methyl Cellulose ◽  
Soluble Solids ◽  
Organoleptic Properties ◽  
Low Fat Diet ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Carboxy Methyl

Indonesia is the fourth largest sweet potato producing country in the world. However, the number of sweet potato utilization is still non optimal. One of the most popular sweet potato cultivars is Cilembu sweet potato. Velva is a frozen dessert which is made from mashed fruit (puree) with addition of water and sucrose. Fat content in velva is much lower than the ice cream, it is suitable to be consumed by vegetarian and those who are on low-fat diet. The velva making process may serve as an alternative of sweet potato utilization and will increase its economic value. One of the factors that affects the texture of velva is the type and amount of stabilizers used. This research aims to determine the optimal amount of Carboxy Methyl Cellulose(CMC) to yield Cilembu sweet potato velva with good characteristics and organoleptic properties of the panelists preferences. The method used is the experimental method with completely randomized design (CRD) consisted of 6 treatments of CMC addition (0.00%, 0.20%, 0.40%, 0.60%, 0.80%, and 1.00%) and replicated 4 times. The final results showed that the sweet potato velva with addition of 0.60% CMC was the best treatment. The velva has rate of melting 712.50 seconds, overrun 19.69 %, and the amount of total soluble solids 27obrix. This velva has qualified the standard of rate of melting, according to Arbuckle and Marshall (1996) the ice cream’s rate of melting  in 20oC  is 10-15 minutes. Keywords: velva; sweet potato; CMC; characteristics

scholarly journals PENGARUH AIR REBUSAN DAUN HARENDONG BULU (Clidemia hirta) TERHADAP KADAR KOLESTROL MENCIT (Mus musculus)

2020 ◽  
Vol 3 (1) ◽  
pp. 1-6
Author(s):  
Tuginah T ◽  
Dian Samitra ◽  
Eka Lokaria
Keyword(s):  
Experimental Study ◽  
Mus Musculus ◽  
Blood Cholesterol ◽  
Male Mice ◽  
Test Calculation ◽  
Experimental Animals ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Boiled Water

This study aims to determine the effect of giving boiled water leaves Clidemia hirta on the levels of male webster swiss mice cholesterol. This type of research is an experimental study using the Completely Randomized Design (CRD) method which consists of 5 treatments with 5 repetitions. The experimental animals in this study were male mice which were divided into 5 groups namely P0 (aquadest), P1 (MDLT + PTU + boiled water 0.13 ml/bb), P2 (MDLT + PTU + boiled water 0.26 ml/bb), P3 (MDLT + PTU + boiled water 0.39 ml/bb), and P4 (Simvastatin 10 mg). The treatment was carried out using the gavage method using a gastric sonde device, giving boiled bristle leaves boiled water in the morning for 7 consecutive days carried out in the morning. Retrieval of blood cholesterol levels data by cutting the tail of mice and the next drop blood on the cholesterol strip Autocheck tool. Based on the results of the Kruskal Wallis test calculation states that Hcount <Htable (4.626 <9.49), it can be concluded that the provision of boiled water leaves of Clidemia hirta does no effect significant in reducing levels of male Swiss Webster mice (Mus musculus) cholesterol levels.

scholarly journals PENGARUH POLISAKARIDA KRESTIN DARI EKSTRAK JAMUR Coriolus versicolor TERHADAP PROFIL PROTEIN TERSTIKULER DAN KADAR TESTOSTERON Mus musculus

el–Hayah ◽  
2016 ◽  
Vol 5 (4) ◽  
pp. 169
Author(s):  
Sri Puji Astuti Wahyuningsih ◽  
Virid Gibson ◽  
Alfiah Hayati
Keyword(s):  
Molecular Weight ◽  
Treatment Group ◽  
Mus Musculus ◽  
Control Group ◽  
Protein Profiles ◽  
Testosterone Levels ◽  
Randomized Design ◽  
Sds Page ◽  
Elisa Technique ◽  
Completely Randomized Design

<em>The purpose of this research was to determine the effect of polysaccharide krestin</em> (<em>PSK) </em><em>on the testicular protein profiles and testosterone levels of Mus musculus with variety of dosages. This research used a completely randomized design. It were devide into four treatment group i.e. control group, PSK treatment at a dose of  15, 30, 60 mg/kgBW. Each group had six replications. Testicular proteins were isolated by flushing technique and analized by SDS-PAGE. Testosterone levels were analized using ELISA technique at wavelength 450 nm. Protein bands analysis showed that there were no diversification between four treatments. Molecular weight of protein bands were 87, 63, 57, 35, and 30 kDa. The results of research showed that the testosterone levels at dosage 60 mg/kgBW had significanly different with control, PSK treatment of 15 and 30 mg/kgBW. PSK treatment of  60 mg/kgBW had lowest level at dosage, i.e. 25946.8 ρg/mL. It can be concluded that giving variety of dosages of polysaccharide krestin did not affect to testicular protein profiles but giving effect to testosterone levels of Mus musculus.</em>

scholarly journals THE STATE OF CHOLESTEROL LEVEL IN HYPERTENSION IN SADANANYA HEALTH CENTER

2021 ◽  
Vol 4 (2) ◽  
pp. 80-85
Author(s):  
Irpan Ali Rahman ◽  
Endrian Mulyadi Justitia Waluyo ◽  
Shafira Aisyah Darmawan
Keyword(s):  
Blood Pressure ◽  
Total Cholesterol ◽  
Health Center ◽  
Cholesterol Level ◽  
Blood Cholesterol ◽  
High Total Cholesterol ◽  
High Cholesterol ◽  
Hypertensive Patients ◽  
Cholesterol Levels ◽  
Quantitative Descriptive

Hypertension is an increase in systolic blood pressure above 140 mmHg and diastolic blood pressure above 90 mmHg. The number of hypertension sufferers has increased each year, in 2015 it reached 19,552, in 2016 it reached 24,750 and in 2017 it reached 38,057. In 2017 there were 115 hypertensive patients recorded in the report book that checked their health at the Sadananya Health Center. One of the causes of the high incidence of hypertension is cholesterol caused by the consumption of inappropriate food. One of the laboratory examinations to support hypertension diagnosis is blood cholesterol examination which can show excess cholesterol which makes hypertension difficult to control. To know the description of total cholesterol levels in hypertensive patients at the Sadananya Health Center. Quantitative descriptive, the population in this study were people with hypertension at the Sadananya Health Center. Sampling with accidental sampling, as many as 30 respondents. The cholesterol examination method used is CHOD-PAP. The results showed that blood pressure in respondents all had high blood pressure, namely >140/90 mmHg (100%), a high cholesterol level of 24 respondents (80%), blood pressure 140-150 who had high cholesterol as many 13 respondents, blood pressure 160-170 who had high cholesterol as much 6 respondents, blood pressure >180 who had high cholesterol as much 5 respondents. This study concludes that hypertensive clients have more high total cholesterol levels, which is as much as 80% and normal 20%. More hypertensive patients have high total cholesterol levels, which are 80% and 20% normal.

scholarly journals Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

2020 ◽  
Vol 21 (2) ◽  
pp. 124-130
Author(s):  
Mhd Zalil Efendi ◽  
Ramadhan Sumarmin ◽  
M. Syukri Fadil
Keyword(s):  
Wound Healing ◽  
Adult Male ◽  
Mus Musculus ◽  
Male Mice ◽  
Pharmacological Activities ◽  
Active Compounds ◽  
Randomized Design ◽  
Wide Range ◽  
Completely Randomized Design ◽  
Etlingera Elatior

Torch ginger has a wide range of good antimicrobial, antioxidant, anticancer, larvicidal and repellent activities. Active compounds in Torch ginger that affect pharmacological activities are phenols, polyphenols, flavonoids, and terpenoids. Based on these ingredients Torch ginger can be used to heal wounds. This study aims to observe the effect of Torch ginger Umbut extract on wound healing in mice. This study hopes to add information about the effect of Torch ginger umbut extract on the healing of cuts in mice so that it can be another alternative for wound healing and can be a reference for other researchers. This study used a completely randomized design with 5 treatments and 3 replications. Tests carried out on adult male mice. The results showed that the optimal wound healing in P2 is treatment with 10% Torch ginger umbut extract which requires a range of wound healing 7-8 days. Based on these results, Torch ginger umbut extract can heal wounds.

scholarly journals Pengaruh Pemberian Ekstrak Buah Bakau (Rhizopora mucronata) Terhadap Penurunan Kadar Gula Darah Mencit (Mus musculus)

2017 ◽  
Author(s):  
A. Mu’nisa ◽  
Karina Ahli Rosi
Keyword(s):  
Analysis Of Variance ◽  
Mus Musculus ◽  
Methyl Cellulose ◽  
Carboxy Methyl Cellulose ◽  
Carboxy Methyl

Bakau (Rhizopora mucronata) merupakan tanaman yang sering dijumpai pada hutan mangrove yang diketahui memiliki kandungan antioksidant yang cukup tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak buah bakau (Rhizopora mucronata) terhadap penurunan kadar gula darah mencit (Mus musculus) galur ICR jantan. Buah bakau diekstraksi menggunakan pelarut metanol 96 % dengan cara maserasi. Penelitian ini merupakan rancangan acak lengkap (RAL) yang terdiri dari 5 perlakuan dan 5 ulangan yakni kelompok normal (aquadest), kelompok positif (glibenklamid), kelompok pemberian ekstrak buah bakau dengan dosis 125, 250 dan 500 mg/kg BB. Ekstrak dilarutkan menggunakan Carboxy Methyl Cellulose (CMC) 0,5 % dan diberikan pada mencit secara oral yang sebelumnya telah diinduksi aloksan sebesar 130 mg/kg BB. Data dianalisi dengan Analysis of Variance (ANOVA) dan dilanjutkan dengan uji Duncan (α 0,05). Hasil penelitian menunjukan ekstrak buah bakau (Rhizopora mucronata) dengan dosis 500 mg/kg BB memiliki efektfitas paling tinggi dalam menurunkan kadar gula darah mencit yang mengalami hiperglikemia dengan persentase penurunan 63,2 %. Hasil ini berbeda nyata dengan kelompok kontrol positif (glibenklamid) yang memiliki persentase 87,6 %. Pemberian ekstrak buah bakau. (Rhizopora mucronata) mampu menurunkan kadar gula darah mencit (Mus musculus) jantan hiperglikemia. Dokumen ini merupakan bagian dari Prosiding Simposium Nasional MIPA 2017 (Makassar, 24 Februari 2017), diunggah oleh Ansari Saleh Ahmarhttp://mipa.unm.ac.id/mipaopen/

Sign in / Sign up

Export Citation Format

Share Document