scholarly journals PENGARUH AIR REBUSAN DAUN HARENDONG BULU (Clidemia hirta) TERHADAP KADAR KOLESTROL MENCIT (Mus musculus)

2020 ◽  
Vol 3 (1) ◽  
pp. 1-6
Author(s):  
Tuginah T ◽  
Dian Samitra ◽  
Eka Lokaria
Keyword(s):  
Experimental Study ◽  
Mus Musculus ◽  
Blood Cholesterol ◽  
Male Mice ◽  
Test Calculation ◽  
Experimental Animals ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Boiled Water

This study aims to determine the effect of giving boiled water leaves Clidemia hirta on the levels of male webster swiss mice cholesterol. This type of research is an experimental study using the Completely Randomized Design (CRD) method which consists of 5 treatments with 5 repetitions. The experimental animals in this study were male mice which were divided into 5 groups namely P0 (aquadest), P1 (MDLT + PTU + boiled water 0.13 ml/bb), P2 (MDLT + PTU + boiled water 0.26 ml/bb), P3 (MDLT + PTU + boiled water 0.39 ml/bb), and P4 (Simvastatin 10 mg). The treatment was carried out using the gavage method using a gastric sonde device, giving boiled bristle leaves boiled water in the morning for 7 consecutive days carried out in the morning. Retrieval of blood cholesterol levels data by cutting the tail of mice and the next drop blood on the cholesterol strip Autocheck tool. Based on the results of the Kruskal Wallis test calculation states that Hcount <Htable (4.626 <9.49), it can be concluded that the provision of boiled water leaves of Clidemia hirta does no effect significant in reducing levels of male Swiss Webster mice (Mus musculus) cholesterol levels.

scholarly journals PENGARUH PEMBERIAN EKSTRAK RUMPUT KEBAR (Biophytum petersianum Klotzsch) TERHADAP JUMLAH SEL SERTOLI MENCIT (Mus musculus) YANG DIPAPAR 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN

2020 ◽  
Vol 8 (1) ◽  
pp. 45
Author(s):  
Cyrcilia Relita Berlina ◽  
Hana Eliyani ◽  
Abdul Sami ◽  
Widjiati Widjiati ◽  
Sri Mulyati ◽  
...  
Keyword(s):  
Experimental Study ◽  
Sertoli Cell ◽  
Adult Male ◽  
Mus Musculus ◽  
Sertoli Cells ◽  
Male Mice ◽  
Randomized Design ◽  
Biophytum Petersianum ◽  
Completely Randomized Design ◽  
Per Oral

This study  was aimed  to know  the effect of Kebar grass  extract  on amount of mice  Sertoli  cell exposed  by TCDD.  This study was  experimental   study  with completely   randomized  design.  Thirty adult  male  mice  of Mus  musculus strain Balb/C,  age 11 weeks  and  weight   25 - 30 ~were    used.  Mice were divided   into five groups,   that  were:  K- was  control  (aquadest   0)   mL); K+ was  injected  with TCDD  at  dose  of 7 µg/kg   BW;  Pl  was  injected  with TCCD  and  administrated with   Kebar   extract   (0,045 mg/  g  BW/day);   P2 was   injected   with   TCCD  and administrated  with  Kebar  extract  (0,080 mg/ g BW/day);   P3 was  injected  with TCDD and  administrated with  Kebar extract  (0,135 mg/  g BW/day).   Kebar grass extract  was  administrated in 53 days.  Mice were sacrificed  and  right  testis organs were  taken.  Then, histology   preparat  with  HE  staining   were  made  and  Sertoli cells  were  counted.    Data were   analyzed  by  One  Way  ANOV A  followed   by Duncan test  (a  =  0,05).   The result  of this  study   showed that  administration  of Kebar  grass  extract  affected  amount  of mice sertoli  cells.  K+ (2,92a±0,109) showed significance difference  (p<0,05) compared   to Pl (5,00b±0,374), P2 (7,64c±0,409)  and P3 (9,68ct±0,363).  Meanwhile, amount   of Sertoli cells of P3 at the highest  dose  did not  show  significance difference   (p>0,05)  with  K-  (10,16<l±0,829).  The conclusion of this study was  administration of Kebar  grass  extract  per  oral in 53 days  could maintain amount  of mice Sertoli cell exposed  by TCDD. 

scholarly journals Bioactivity of Torch Ginger Umbut Extract (Etlingera elatior) Against Heal Wounds of Mice (Mus musculus)

2020 ◽  
Vol 21 (2) ◽  
pp. 124-130
Author(s):  
Mhd Zalil Efendi ◽  
Ramadhan Sumarmin ◽  
M. Syukri Fadil
Keyword(s):  
Wound Healing ◽  
Adult Male ◽  
Mus Musculus ◽  
Male Mice ◽  
Pharmacological Activities ◽  
Active Compounds ◽  
Randomized Design ◽  
Wide Range ◽  
Completely Randomized Design ◽  
Etlingera Elatior

Torch ginger has a wide range of good antimicrobial, antioxidant, anticancer, larvicidal and repellent activities. Active compounds in Torch ginger that affect pharmacological activities are phenols, polyphenols, flavonoids, and terpenoids. Based on these ingredients Torch ginger can be used to heal wounds. This study aims to observe the effect of Torch ginger Umbut extract on wound healing in mice. This study hopes to add information about the effect of Torch ginger umbut extract on the healing of cuts in mice so that it can be another alternative for wound healing and can be a reference for other researchers. This study used a completely randomized design with 5 treatments and 3 replications. Tests carried out on adult male mice. The results showed that the optimal wound healing in P2 is treatment with 10% Torch ginger umbut extract which requires a range of wound healing 7-8 days. Based on these results, Torch ginger umbut extract can heal wounds.

scholarly journals PENGARUH NATRIUM SIKLAMAT TERHADAP HISTOPATOLOGI ORGAN MENCIT (Mus musculus) DAN SUMBANGSIHNYA PADA MATERI STRUKTUR DAN FUNGSI JARINGAN HEWAN DI SMA/MA

1970 ◽  
Vol 4 (2) ◽  
pp. 82-100
Author(s):  
Ummi Hiras Habisukan
Keyword(s):  
Mus Musculus ◽  
Histological Structure ◽  
Male Mice ◽  
Renal Histopathology ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Sodium Cyclamate

Sweeteners are one of the components which are often added to foodstuffs. Synthetic sweetenersare widely used in the society is sodium cyclamate. The purpose of this study was to determine thesodium cyclamate on the histological structure of the glomerulus of mice (Mus musculus). Thisresearch used 12 male mice (Mus musculus) with Completely Randomized Design (CRD) so thereare 4 groups (control, PI: 0,55 mg/grbb, p2: 1,1 mg/grbb, and p3: 1,65 mg/grbb) with 3 replicationsfor 24 days. Parameters observed were edema and comparison of area glomerulus with Bowmancapsule. The result showed that sodium cyclamate had effect to edema and tended to areaglomerulus with Bowman capsule comparization. Based on the research could be concluded thatsodium cyclamate had effect to renal histopathology. This research will be used as media inlearning process.

scholarly journals KAJIAN EFEKTIVITAS EKSTRAK GEL IKAN TOMAN (Channa micropeltes) PADA LUKA BAKAR MENCIT (Mus musculus)

2019 ◽  
Vol 15 (2) ◽  
pp. 184
Author(s):  
Firlianty Firlianty ◽  
Hermansyah Hermansyah ◽  
Windarina Samosir
Keyword(s):  
Data Analysis ◽  
Experimental Method ◽  
Mus Musculus ◽  
Control Treatment ◽  
Test Results ◽  
Male Mice ◽  
In Vivo Test ◽  
Randomized Design ◽  
Completely Randomized Design

This study aims to determine the study of the effectiveness of toman fish (Channa micropeltes) gel extract on healing burns of mice (Mus musculus). This research was conducted for 4 months, starting from September 2018 to January 2019. This study used the experimental method and data analysis using a completely randomized design with 4 children and three replications: treatment A as control, treatment B giving toman fish extract gel (Channa micropeltes ) 1.5%, treatment C 3% and treatment D 4.5%. The results showed that on day 4, day 8 and day 12 showed that the administration of gel extract had a significant effect on changes in the length of burns of mice (Mus musculus) (P>0.05). In vivo test results on male mice with toman fish gel extract can capture the healing of burns in mice.

scholarly journals Propolis Potential Toward the Amount of Limphoblast and Spleen Diameter of Male Mice (Mus musculus)

2017 ◽  
Vol 3 (6) ◽  
pp. 386
Author(s):  
Werstant Adhityananda Rinaldhi ◽  
Eka Pramyrtha Hestianah ◽  
Sri Mumpuni Sosiawati ◽  
Lita Rakhma Yustinasari
Keyword(s):  
Body Weight ◽  
Statistical Analysis ◽  
Mus Musculus ◽  
White Male ◽  
White Pulp ◽  
Male Mice ◽  
Positive Correlation ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Range Test

The aim of this research was to find out the effect of propolis in the amount of lymphoblast and the correlation between the treatment of propolis with spleen diameter each of white male mice (Mus musculus). This research used  25 male white mices which are 12 weeks old has 25-35 gram of body weight. They were divided randomly into five groups. (P0) as control  was given 0,5 ml aquades/day, and other group were given propolis for 0.4 mg/0.03kg/day (P1), 0.8 mg/0.03kg/day (P2), 1.6 mg/0.03kg/day (P3), and 3.2 mg/0.03kg/day (P4). After two weeks treatment, 25 mices were sacrificed their spleen were then used in histological preparation with HE staining. The data were analyzed by ANOVA method based on Completely Randomized Design and further analyzed by Duncan's Multiple Range Test. The result from statistical analysis showed that treatment with propolis increased the amount of lymphoblast also the spleen diameter of white male mice (p<0,05) and show positive correlation amount of lymphoblast and white pulp spleen diameter. Keyword: propolis, lymphoblast, white pulp, spleen

scholarly journals Potensi Dedak Padi yang Difermentasi dengan Enzim Fitase dalam Pakan Basal Terhadap Kolesterol Total Darah Ayam Petelur

2021 ◽  
Vol 9 (2) ◽  
pp. 92
Author(s):  
Yulia Nurfitri ◽  
Mirni Lamid ◽  
Margareth Gandul Atik Yuliani ◽  
Mohamad Anam Al-Arief ◽  
Retno Sri Wahyuni ◽  
...  
Keyword(s):  
Rice Bran ◽  
Laying Hen ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Fish Oil Supplementation ◽  
Total Blood Cholesterol

This study aimed to evaluate the potential of rice bran fermented by the enzyme phytase in basal feed to the total blood cholesterol level of laying hen. This research use an experimental method in vivo with a completely randomized design consisting of six treatments and four replications in each treatment. The experimental animals used 24 48-week-old female laying hen strain Isa Brown. The treatment wa given basal feed substituted with different percentage of fermented rice bran by phytase enzyme and 2% lemuru fish oil supplementation. In this research the amount of fermented rice bran by phytase enzyme substituted on basal feed was: treatment P0 (-) (0%), P0 (+) (0%), P1 (5%), P2 (10%) P3 (15%) and P4 (20%). The results of the statistical analysis showed that there are no significant differences (p> 0.05) on total blood cholesterol levels in all treatments. The conclusion of the research is that rice bran fermented by phytase enzymes tends to decrease total blood cholesterol levels in laying hen.

scholarly journals Pengaruh Ekstrak Daun Pedada (Sonneratia caseolaris) Sebagai Antihiperkolesterolmia Pada Mencit (Mus musculus)

bionature ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ramlah Ramlah
Keyword(s):  
Total Cholesterol ◽  
Mus Musculus ◽  
Methanol Extract ◽  
Methyl Cellulose ◽  
High Cholesterol ◽  
Sonneratia Caseolaris ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Carboxy Methyl

Abstract. This study was conducted to determine the effect of extract leaf pedada (Sonneratia caseolaris) to total cholesterol levels of mice (Mus musculus) male ICR strain. Leaf pedada extracted using 96% methanol by maceration. This study is a completely randomized design (CRD), which consists of 5 treatments and 5 replicates the normal group (distilled water), positive group (Simvastatin), a group of leaf pedada extract at a dose of 125, 250 and 500 mg / kg. The extract was dissolved using Carboxy Methyl Cellulose (CMC) 0.5% and given orally in mice which had previously been given a high cholesterol feed. The results showed the methanol extract of leaves cemba with the dose of 500 mg/kg hads the highest effectiveness in lowering total cholesterol levels in mice which have hypercholesterolemia with a 30,20 % percentage drop. These results indicate that of the giving leaf extract pedada (Sonneratia caseolaris) able to lower total cholesterol levels of mice (Mus musculus) male hypercholesterolaemia.Keywords: Antihipercholesterolemia, total cholesterol, Methanol extract of  leaf pedada (Sonneratia caseolaris), mice (Mus musculus) ICR male.

scholarly journals PENGARUH AIR REBUSAN DAUN HARENDONG BULU (Clidemia hirta) TERHADAP KADAR GULA DARAH MENCIT (Mus musculus)

2020 ◽  
Vol 3 (1) ◽  
pp. 7-12
Author(s):  
Okta Malia ◽  
Dian Samitra ◽  
Eka Lokaria
Keyword(s):  
Blood Sugar ◽  
Mus Musculus ◽  
Design Research ◽  
Control Group ◽  
Treatment Groups ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Sugar Levels ◽  
Boiled Water ◽  
One Way Anova

This study aims to determine the effect of the water boiled leaves of Clidemia hirta on blood sugar levels in Swiss Webster mice (Mus musculus). This research using a completely randomized design research design (CRD) with 5 treatment groups namely; Aquades control group (P0), 3 g sucrose treatment (P1), 3 g sucrose treatment + boiled bristle leaves boiled water at a dose of 0.13 ml/KgBB (P2), 3 g sucrose treatment + boiled bristle leaves boiled water at a dose of 0.26 ml/KgBB (P3), 3 g treatment of sucrose + boiled bristle leaves boiled water at a dose of 0.39 ml/KgBB (P4). Before administration of the extract, mice in the treatment groups P1, P2, P3 & P4 were induced using 3 g of sucrose for 5 days. Then after 5 days for groups P2, P3, and P4 followed by giving boiled water leaves for 7 days. The analysis result of One Way Anova Test shows that Fcount > Ftable (18.86 > 2.51). This shows the boiled water affects the blood sugar levels of male Swiss Webster mice. The concentration of extract at P4 (0.39 ml/KgBB) was more effective in reducing blood sugar levels.

scholarly journals 15. The Effect of Celery (Apium graveolens L.) Leaf Infusion on Blood Cholesterol Levels in White Male Rat (Rattus norvegicus) Induced by Alloxan

2019 ◽  
Vol 13 (1) ◽  
pp. 108-113
Author(s):  
Kiky Moelviani ◽  
Sugito Sugito ◽  
Roslizawaty Roslizawaty ◽  
Zuhrawati NA ◽  
Rusli Rusli ◽  
...  
Keyword(s):  
Rattus Norvegicus ◽  
White Male ◽  
Male Rats ◽  
Blood Cholesterol ◽  
Apium Graveolens ◽  
Infusion Therapy ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Therapy Treatment

This study aimed to determine the effect of celery (Apium graveolens L.) leaves infusion on blood cholesterol levels in male rats (Rattus norvegicus) induced by alloxan. The sample used in this study were 25 white male rats Wistar strained aged 3-4 months with a bodyweight of 150-200 grams. The design used are were unidirectional pattern of completely randomized design with 5 treatments and 5 replications. Treatment 1 (P1) rats  were given with the standard feed. Treatment 2 (P2),rats  were induced by alloxan. Treatment 3 (P3) rats were induced by alloxan and given 2 ml of 5% celery leaf infusion therapy. Treatment 4 (P4) rats  were induced by alloxan and given 2 ml of 10% celery leaf infusion therapy. Treatment 5 (P5) rats  were induced by alloxan and given 2 ml of 15% celery leaf infusion therapy. Celery leaf infusion was given every morning and evening. Administration of  alloxan with a single dose of 150 mg / kg in  IP and celery leaf infusion therapy were given for 14 days. Rat blood cholesterol levels checked using the CHOD-PAP. Data were analyzed using ANOVA completely randomized design. Mean (± SD) of cholesterol in treatment P1, P2, P3, P4 and P5 sequence was 52.8 ± 9.09; 50.4 ± 18.53; 42.6 ± 4.51; 40.2 ± 52.8 ± 7.19 and 2.39. The results showed that the infusion of celery leaves was not showing any effect (P 0.05) on blood cholesterol levels of white male rats induced by alloxan. Administration of celery leaves (Apium graveolens L.) infusion for 14 days with a concentration of 5%, 10% and 15% have no effect on blood cholesterol levels in male rats induced by alloxan.

scholarly journals The Effect Of Rajalele Probiotic On Survival Rate Of Fish Juvenile Pangasius pangasius, Oreochromis niloticus, Cyprinus carpio

2020 ◽  
Vol 6 (1) ◽  
pp. 88-95
Author(s):  
Marlina Doloksaribu ◽  
Robert Martua Simanjuntak ◽  
Ied Hidayani Parinduri
Keyword(s):  
Social Sciences ◽  
Experimental Study ◽  
Data Analysis ◽  
Survival Rate ◽  
Cyprinus Carpio ◽  
Oreochromis Niloticus ◽  
Fish Farming ◽  
Randomized Design ◽  
The Social ◽  
Completely Randomized Design

The use of probiotics is certainly one of the solutions in overcoming the problem of increasing seed in fish farming. One of them is the use of probiotic king catfish, in this study tested on catfish, tilapia and goldfish. This research is an experimental study. The design used in this study was a Completely Randomized Design with 4 treatments 3 replications. Data analysis used Statistical Package for the Social Sciences version 15. The results of the analysis of the highest seed survival rate were obtained on Pangasius pangasius (95%), on Oreochromis niloticus (83,33 %), and Cyprinus carpio (80%). The treatment of Rajalele probiotics has a very significant effect (very significant) Fanalysis (23.01) > Ftable 0.01 (7.59) on the graduation of Pangasius pangasius, Oreochromis niloticus, and Cyprinus carpio. The conclusion of this study shows that the survival rate the highest in Pangasius pangasius

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