scholarly journals Comparison of pharmacological activity of hawthorn fruits preparations

2020 ◽  
Vol 5 (2) ◽  
pp. 136-139
Author(s):  
Vladimir A. Kurkin ◽  
Elena N. Zaitceva ◽  
Elena V. Avdeeva ◽  
Viktoriya V. Stenyaeva ◽  
Ilnur Kh. Shaikhutdinov ◽  
...  
Keyword(s):  
Comparative Study ◽  
Raw Materials ◽  
Antidepressant Activity ◽  
Diuretic Action ◽  
Plant Raw Materials ◽  
Alcohol Water ◽  
Diuretic Agents ◽  
The Comparative Study ◽  
White Mongrel ◽  
Saluretic Activity

Objectives - a comparative study of antidepressant activity and diuretic action of water and water-alcohol preparations of the fruits of Crataegus sanguinea Pall. and Crataegus submollis Sarg. Materials and methods. The study covers the water and alcohol-water extracts from the fruits of hawthorn blood-red (Crataegus sanguinea Pall.) and Quebec hawthorn (Crataegus submollis Sarg.). The comparative study of the antidepressant activity and the diuretic action of the preparations was carried out on white mongrel rats of both sexes. Results. The liquid extracts of fruits Crataegus sanguinea Pall. and Crataegus submollis Sarg. at a dose of 100 μl/kg revealed an antidepressant activity. Decoctions of Crataegus sanguinea Pall. and Crataegus submollis Sarg. at a dose of 100 μl/kg had a pronounced diuretic and saluretic activity. Pharmacotherapeutic effects of the studied preparations can be explained by the presence of flavonoids in them. Conclusion. The preparations of the fruits of Crataegus sanguinea Pall. and Crataegus submollis Sarg. can be recommended as antidepressant and diuretic agents. The fruits of Crataegus submollis Sarg. are the promising medicinal plant raw materials.

scholarly journals THE STUDY OF THE FLAVONOIDS AND ANTIDEPRESSANT ACTIVITY OF THE LEAVES AND LIQUID EX-TRACT OF CRATAEGUS SUBMOLLIS

2018 ◽  
pp. 105-112 ◽  
Author(s):  
Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin) ◽  
Елена (Elena) Николаевна (Nikolayevna) Зайцева (Zaitseva) ◽  
Татьяна (Tat'yana) Владимировна (Vladimirovna) Морозова (Morozova) ◽  
Ольга (Ol'ga) Евгеньевна (Evgen'evna) Правдивцева (Pravdivtseva) ◽  
Елена (Elena) Владимировна (Vladimirovna) Авдеева (Avdeeva) ◽  
...  
Keyword(s):  
Russian Federation ◽  
Raw Materials ◽  
Antidepressant Activity ◽  
Raw Material ◽  
High Yield ◽  
Total Flavonoids ◽  
Plant Raw Materials ◽  
Extraction Solvent ◽  
Optimum Extraction ◽  
Additional Point

Nowadays flowers and fruits of various types of hawthorn are widely used as cardiotonic drugs in Russian Federation. In our opinion a promising species for harvesting raw materials is Quebec hawthorn (Crataegus submollis Sarg., Rosaceae). Quebec hawthorn is successfully cultivated on the territory of the Russian Federation and is characterized by rapid growth and high yield in comparison with wild species. An additional point is that one of the possible types of raw materials are hawthorn leaves widely used abroad. Quebec hawthorn leaves contain flavonoids, among which there is a hyperoside. The maximum of the absorption curve of the extract solution of Quebec hawthorn leaves with an aluminum chloride solution of 412 nm. We have developed a quantification method for determination the total flavonoids in the Quebec hawthorn leaves calculated as hyperoside. It was established that the optimum extraction solvent for this raw material is 70% ethanol. The level of content and dynamics of accumulation of the total flavonoids in the Quebec hawthorn leaves during the growing season of 2017 was studied. The maximum content of total flavonoids in the Quebec hawthorn leaves (3.12 ± 0.05% calculated on hyperoside) is observed in May, during plant flowering. The liquid extract based on Quebec hawthorn leaves possesses moderate antidepressant activity. For this reason, leaves of Quebec hawthorn leaves are promising medicinal plant raw materials.

scholarly journals Comparative study of the elemental composition in raw materials of plants of genus Geum L.

2021 ◽  
pp. 70-77
Author(s):  
С. А. Козира ◽  
Т. М. Гонтова ◽  
С. І. Степанова ◽  
В. П. Гапоненко ◽  
В. В. Машталер ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Comparative Study ◽  
Atomic Absorption ◽  
Elemental Composition ◽  
Raw Materials ◽  
Biologically Active ◽  
Raw Material ◽  
Material Base ◽  
Plant Raw Materials ◽  
Microelement Composition

Among the relevant for the modern pharmacy problems, there is a need for the rational complex use of known medicinal plants, as well as the search for new sources of natural biologically active compounds in order to expand the list of official medicinal plants and raw material base. Species of genus Geum L. contain a number of biological active substances and are promising sources of raw materials for the production of antimicrobial, astringent, anti-inflammatory, and hemostatic medicines. Pharmacological activity of these plants results from their multi-component chemical composition, including tannins, flavonoids, macro- and microelements and other compounds. The aim of thе study was to compare the elemental composition of herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. of Ukrainian flora. The objects of the study were the samples of herb and rhizome with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. (dried raw materials) which were collected in the Kharkiv region, Ruski Tishki village, in June-August 2018–2019. The determination of the qualitative composition and quantitative content of elements was carried out by atomic absorption spectroscopy with atomization in an air-acetylene flame using a spectrometer CAS 120 («Selmi», Sumy, Ukraine). In the studied samples, 19 elements were determined, including 5 macroelements and 14 microelements. The data about accumulation of elements in investigated herb of G. urbanum L., G. aleppicum Jacq., G. rivale L. can be arranged in descending order as follows: K > Ca > Si > Mg > P > Fe > Al > Na > Sr > Zn, and in rhizomes with roots as follows – K > Si > Ca > Mg > Fe > P > Al > Na > Sr > Zn. The content of toxic elements such as cobalt, cadmium, arsenic, and mercury was within the permissible limits for plant raw materials and food. For the first time, a comparative study of the macro- and microelement composition in herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. has been carried out. Using the method of atomic absorption spectral analysis, 19 elements have been identified and their content has been determined, among which К, Ca, Mg, Si, P, Fe, Al, Na, Mn, Zn predominantly accumulate.

scholarly journals The study of the Crataegus sanguinea Pall. extractsdiuretic and antidepressant action

2018 ◽  
Vol 17 (4) ◽  
pp. 65-71 ◽  
Author(s):  
V. A. Kurkin ◽  
E. N. Zaitceva ◽  
T. V. Morozova ◽  
O. E. Pravdivtseva ◽  
A. V. Dubishchev ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Comparative Study ◽  
Antidepressant Activity ◽  
Complex Treatment ◽  
Diuretic Activity ◽  
Cardiovascular Pathology ◽  
White Rats ◽  
Liquid Extract ◽  
The Comparative Study ◽  
Antidepressant Action

The purposeof the study is to study the urinative and antidepressant activities of liquid extracts based on flowers, shoots, leaves and fruits ofCrataegus sanguineaPall. to substantiate their use in the development and  manufacture of drugs for the complex treatment of cardiovascular diseases.Materials and methods.The comparative study of the diuretic and antidepressant activity of liquid extracts based on leaves, flowers, shoots and fruits Crataegus sanguinea was conducted. The liquid extracts were obtained on the basis of dried leaves, flowers, shoots and fruits of Crataegus sanguinea. All liquid extracts were obtained in the ratio “raw – extractant” 1 : 1, in all cases the extracting agent was ethyl alcohol 70%. The studies were conducted using outbred white rats of both sexes. All preparations were examined in a dose of 100 μl/kg. The diuretic activity of Crataegus sanguineaof liquid extracts in chronic experiments was determined, 4 h and 24 h portions of urine were collected. The antidepressant activity was tested using the “Desperation” testResults.During the experiment, the diuretic activity of the liquid extract Crataegus sanguinea, as well as the antidepressant activity of liquid extracts of Crataegus sanguinea, shoots and fruits were revealed. Conclusion. Crataegus sanguinea preparations have complex nephrotropic and neurotropic action and can be recommended for use in the cardiovascular pathology treatment.

TO THE QUESTION OF STUDYING THE POSSIBILITIES OF USING LEAVES AND DRY STRAWBERRY EXTRACT IN MEDICINE

2020 ◽  
pp. 132-136
Author(s):  
Yaborova O. V ◽  
Kuritsyn A.V. ◽  
Kylosova I.A. ◽  
Gulyaev D.K.
Keyword(s):  
Leaf Extract ◽  
Raw Materials ◽  
Practical Interest ◽  
Dosage Forms ◽  
Practical Application ◽  
Plant Raw Materials ◽  
Scientific Justification ◽  
Medicinal Properties ◽  
The Comparative Study ◽  
Further Development

In recent years, there has been an increasing interest in medicines produced on the basis of medicinal plant raw materials. Information about the concentration of elements by medicinal plants and substances allows us to see a new aspect of their practical application, to identify new medicinal properties. In this regard, the comparative study of the elemental composition of strawberry leaves and dry strawberry leaf extract is of practical interest for the further development of dosage forms and the formation of scientific justification for their use in medical practice.

scholarly journals Pharmacognostic and pharmacological study of liquid extract of Crataegus Submollis Sarg. Flowers

2020 ◽  
Vol 19 (5-6) ◽  
pp. 160-164
Author(s):  
Ilnur Kh. Shaikhutdinov ◽  
Tatyana V. Morozova ◽  
Vladimir A. Kurkin ◽  
Elena N. Zaitceva ◽  
Olga E. Pravdivtseva ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Raw Materials ◽  
Pharmacological Study ◽  
Antidepressant Activity ◽  
Raw Material ◽  
Intragastric Administration ◽  
Total Flavonoids ◽  
Cardiotonic Agents ◽  
Plant Raw Materials ◽  
Liquid Extract

The flowers and fruits of various species of the hawthorn genus (Crataegus L.) are widely used in domestic and foreign medical practice as cardiotonic agents. A perspective species for collecting of the raw material is Crataegus submollis Sarg. It was determined that 70% ethanol is an optimal extragent for the extraction of flavonoids from Crataegus submollis Sarg. flowers. The content of the total flavonoids in terms of hyperoside in the liquid extract of Crataegus submollis Sarg. flowers is 0,24 0,01%. It was established that liquid extract of Crataegus submollis Sarg. with using of 70% ethanol in case of a single intragastric administration in the dose of 100 l/kg shows significant antidepressant activity. Crataegus submollis Sarg. flowers are the perspective medicinal plant raw materials.

scholarly journals Characterization of carbide lime waste: A comparative study for acid soil stabilization

2021 ◽  
pp. 13-24
Author(s):  
Wafa Atma ◽  
Fatiha Souahi
Keyword(s):  
Comparative Study ◽  
Soil Stabilization ◽  
Raw Materials ◽  
Acid Soil ◽  
Chemical Properties ◽  
Agricultural Field ◽  
Limit Values ◽  
Soil Enrichment ◽  
Generation Plant ◽  
The Comparative Study

The present work aims to study the physical, mineral and chemical properties of carbide lime residues for assessment as an acidic soil modification. Lime carbide waste is a byproduct of an acetylene generation plant located in Reghaia, east of Algiers, Algeria. This residue offers an effective and economical solution in the field of environmental protection, especially as raw materials for wastewater treatment and soil enrichment. Metallic content was studied using X-ray fluorescence (CubiX XRF/PANalytical). Toxic minerals was analyzed by atomic absorption spectroscopy (AAS). According to the comparative study, the characterization and total concentrations of minerals are significantly low and do not exceed the limit values for hazardous wastes and are in line with the standard recommendations of the agricultural field. Lime can be used both environmentally and economically as an amendment to stabilize acidic soils.

Pandhawa Gubah sebagai Representasi Interaksi Metafisik Manusia Jawa dan Perbandingannya dengan Cheritera Pandawa Lima

Manuskripta ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 67
Author(s):  
Novarina Novarina
Keyword(s):  
Comparative Study ◽  
Literary Theory ◽  
Research Method ◽  
Descriptive Analysis ◽  
Literary Study ◽  
Analysis Method ◽  
Research Objects ◽  
Similarities And Differences ◽  
The Difference ◽  
The Comparative Study

Abstract: This research is a comparative literary study that uses Malay and Javanese versions of Mahabarata text sources. The research objects used were the text edition of Pandhawa Gubah (PG) by Sudibjo Z. Hadisutjipto and the text of Cheritera Pandawa Lima (CPL) by Khalid Hussain. The research method used is descriptive-analysis method. In the comparative study used a comparative literary theory proposed by Endraswara (2011). The results of the text comparison reveal the similarities and differences in the image of Bima figures in the Javanese and Malay versions. The equation as a whole is that both texts contain the same heroic storyline and heroic character, Bima. In addition, Indian influence is still evident in the two texts seen from the nuances of Hinduism that exist in both texts. While the difference is seen in the events that accompany Bima's struggle in achieving his victory. Based on these similarities and differences, it can be seen that the authors attempt to represent the concept of metaphysical interactions vertically and horizontally expressed through PG text. --- Abstrak: Penelitian ini adalah satu kajian sastra bandingan yang menggunakan sumber teks Mahabarata versi Melayu dan Jawa. Objek penelitian yang digunakan adalah edisi teks Pandhawa Gubah (PG) karya Sudibjo Z. Hadisutjipto dan teks Cheritera Pandawa Lima (CPL) karya Khalid Hussain. Metode penelitian yang digunakan adalah metode deskriptif-analisis. Dalam telaah perbandingan digunakan teori sastra bandingan yang dikemukakan Endraswara (2011). Hasil perbandingan teks mengungkapkan adanya persamaan dan perbedaan citra tokoh Bima dalam versi Jawa maupun versi Melayu. Persamaan secara keseluruhan adalah kedua teks tersebut mengandung alur cerita kepahlawanan dan tokoh pahlawan yang sama yaitu Bima. Selain itu, pengaruh India masih tampak dalam kedua teks tersebut dilihat dari nuansa Hinduisme yang ada dalam kedua teks. Sementara perbedaannya tampak pada peristiwa-peristiwa yang menyertai perjuangan Bima dalam mencapai kemenangannya. Berdasarkan persamaan dan perbedaan tersebut tampak adanya upaya penulis untuk merepresentasikan konsep interaksi metafisik secara vertikal dan horizontal yang diungkapkan melalui teks PG.

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