TO THE QUESTION OF STUDYING THE POSSIBILITIES OF USING LEAVES AND DRY STRAWBERRY EXTRACT IN MEDICINE

2020 ◽  
pp. 132-136
Author(s):  
Yaborova O. V ◽  
Kuritsyn A.V. ◽  
Kylosova I.A. ◽  
Gulyaev D.K.
Keyword(s):  
Leaf Extract ◽  
Raw Materials ◽  
Practical Interest ◽  
Dosage Forms ◽  
Practical Application ◽  
Plant Raw Materials ◽  
Scientific Justification ◽  
Medicinal Properties ◽  
The Comparative Study ◽  
Further Development

In recent years, there has been an increasing interest in medicines produced on the basis of medicinal plant raw materials. Information about the concentration of elements by medicinal plants and substances allows us to see a new aspect of their practical application, to identify new medicinal properties. In this regard, the comparative study of the elemental composition of strawberry leaves and dry strawberry leaf extract is of practical interest for the further development of dosage forms and the formation of scientific justification for their use in medical practice.

CHOOSING THE OPTIMAL TECHNOLOGY FOR OBTAINING DRY STRAWBERRY LEAF EXTRACT

2021 ◽  
pp. 60-65
Author(s):  
Yaborova O.V. ◽  
Sosnina S.A. ◽  
Turyshev A.Yu.
Keyword(s):  
Raw Materials ◽  
Practical Interest ◽  
Extraction Methods ◽  
Dosage Forms ◽  
Technological Parameters ◽  
Plant Raw Materials ◽  
Scientific Justification ◽  
Optimal Technology ◽  
Further Development

In recent years, there has been an increasing interest in medicines produced on the basis of medicinal plant raw materials. To improve the quality of drug supply to the population and expand the range of medicines, research is relevant to improve the efficiency of the extraction methods used, replacing infusions and decoctions with industrial products. In this regard, the study of the technological parameters of obtaining an extract from the leaves of dry strawberry is of practical interest for the further development of dosage forms with it and the formation of a scientific justification for their use in medical practice.

scholarly journals Standardization of Eucalyptus globulus leaves and Cetraria islandica slan

2021 ◽  
pp. 56-63
Author(s):  
Iryna Fito ◽  
Nataliya Stadnytska
Keyword(s):  
Eucalyptus Globulus ◽  
Raw Materials ◽  
Herbal Medicines ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Qualitative And Quantitative ◽  
Plant Raw Materials ◽  
Further Development ◽  
Layer Chromatography ◽  
Active Substances

The aim. The aim of this study was to propose methods of standardization of Eucalyptus globulus leaves and Cetraria islandica slan by the main group of biologically active substances (BAS). This was done for further development of complex medicines based on Eucalyptus globulus leaves and Cetraria islandica slan. These studies provide an opportunity for further development and standardization of extracts from these plants, and the main aim of this study is the development and standardization of a complex medicine. Materials and methods. Thin layer chromatography was used to determine the presence of these markers. Quantitative values of these biologically active substances were determined by spectrophotometric method according to the relevant methods of the State Pharmacopoeia of Ukraine. Results. Markers for the certification of Cetraria islandica and Eucalyptus globulus have been proposed in this study. Chlorophylls and 1,8-cineole were chosen as a marker for the study of Eucalyptus globulus, and polysaccharides were chosen as a marker for Cetraria islandica. The qualitative and quantitative content of these markers in the studied objects was studied. Further research in this direction will be aimed at developing methods for control and standardization of water and alcohol extracts from these plants. Conclusions. Biologically active substances in medicinal plant raw materials were studied. It is proposed to study extracts and finished products from Eucalyptus globulus leaves and Cetraria islandica slan using these methods. The method of qualitative and quantitative determination of polysaccharides in Cetraria islandica slan is easy to apply and easily reproducible. It is important to be able to standardize Eucalyptus globulus leaves for essential oils and chlorophylls. The biologically active substances-markers found in Eucalyptus globulus leaves and Cetraria islandica slan will be used for the development of herbal medicines, the standardization of which will be carried out for the same compounds.

scholarly journals Ultramafic rocks of the Aganozero chromium ore deposit (South Karelia) as a non-conventional magnesium-silicate raw material for the production of new ceramic materials

2019 ◽  
Author(s):  
V.P. Ilyina ◽  
P.V. Frolov
Keyword(s):  
Raw Materials ◽  
Practical Interest ◽  
Magnesium Silicate ◽  
Ceramic Materials ◽  
Raw Material ◽  
Ultramafic Rocks ◽  
Practical Application ◽  
Ore Deposit ◽  
Chromium Ore ◽  
Technological Level

Ultramafic rocks of the Aganozero chromium ore deposit located in South Karelia are of practical interest as a high-Mg raw material for industrial application. The preliminary results of the study of high-Mg rocks and minerals from the Aganozero deposit for the production of new materials are reported. The high technological level and economic efficiency of the ceramic materials produced, based on Karelia’s high-Mg rocks and industrial minerals, were achieved by reducing energy consumption and simplifying the technological process. The practical application of local types of mineral products will increase the raw materials potential for the production of various types of refractories and industrial ceramics.

scholarly journals BIOTECHNOLOGY IN FORAGE PRODUCTION: CONDITIONS AND DEVELOPMENT PROSPECTS

2010 ◽  
Vol 11 ◽  
pp. 117-122
Author(s):  
H.M. Dyachenko ◽  
N.O. Kravchenko
Keyword(s):  
Raw Materials ◽  
Domestic Market ◽  
Practical Application ◽  
Forage Production ◽  
Plant Raw Materials ◽  
Livestock Sector ◽  
Development Prospects ◽  
Diverse Plant ◽  
Production Conditions

Thepapergeneralizesdataontheadvantagesofbacterialferments and possibilities of their practical application for fodders conservation and provides present-to-day situation on livestock sector in Ukraine supplement with them. The fact of extreme scarce assortment of such products on the domestic market has been established. The prospects of screening of microorganisms` new strains and study of various monoand combined bio products on their basis for silaging diverse plant raw materials was emphasized.

BIOECOLOGY AND COMPONENT COMPOSITION OF EPHEDRINE ALKALOIDS IN SPECIES IN THE DZUNGARIAN ALATAU

Vestnik ◽  
2021 ◽  
pp. 247-253
Author(s):  
Л.С. Кожамжарова ◽  
Н.Т. Аблайханова ◽  
З.Б. Есимсиитова ◽  
А.М. Мухитдинов ◽  
Е.Т. Аблайханов
Keyword(s):  
Raw Materials ◽  
Practical Interest ◽  
Complete Information ◽  
Component Composition ◽  
Raw Material ◽  
Practical Significance ◽  
Material Base ◽  
Full Spectrum ◽  
Plant Raw Materials ◽  
Pharmacological Data

Как показывают данные фармакологических исследований, природные алкалоиды обладают более высоким качеством терапевтического эффекта и срок действия их продолжительнее. При полноценном растительном сырье и достаточных его запасах или при успешной культуре растения тот или иной алкалоид, несомненно, удобнее и экономически выгоднее получать из натурального растительного сырья. В связи с этим практический интерес представляют работы по выявлению и пополнению сведений о фитохимическом составе ценных технических растений флоры Казахстана в свете последних достижений биохимии, биоорганической химии. В статье, для выяснения установление закономерностей изменения количественного содержания и качественного состава эфедриновых алкалоидов от экологических факторов были изучены биоэкологические особенности и выявлены популяции с высоким и пониженным содержанием компонентного состава эфедриновых алкалоидов у видов E.Equisetina в Джунгарском Алатау, а также, установлен полный спектр эфедриновых алкалоидов в вегетативных побегах изучаемого вида. Практическое значение результатов работы является основой для использования сырьевой базы вида E.Equisetina рода Ephedra L., в отечественной фармацевтической промышленности. According to pharmacological data, natural alkaloids have better therapeutic quality and longer duration. If the raw material is full and sufficient, or if the plant culture is successful, some alkaloid is certainly more convenient and economically more profitable to obtain from natural plant raw materials. In this connection, work to identify and complete information on the phytochemical composition of valuable technical plants in the flora of Kazakhstan, in the light of recent advances in biochemistry and bioorganic chemistry, is of practical interest. In the article, to determine the main regularities of changes in the quantitative content and qualitative composition of ephedrine alkaloids from environmental factors, bioecological features were studied and populations with high and low content of the component composition of ephedrine alkaloids in E. Equisetina species in the Dzungarian Alatau were identified. Also, was established the full spectrum of ephedrine alkaloids in vegetative shoots of the studied. The practical significance of the results is the basis for using the raw material base of the species E. Equisetina of the genus Ephedra L. in the domestic pharmaceutical industry.

Overview of the Russian market of herbal products

2021 ◽  
pp. 11-22
Author(s):  
Natalia V. Safonova ◽  
Elena O. Trofimova
Keyword(s):  
Dietary Supplements ◽  
Raw Materials ◽  
Dosage Forms ◽  
Annual Growth Rate ◽  
Sources Of Information ◽  
Herbal Products ◽  
Preparation Methods ◽  
Plant Raw Materials ◽  
Foreign Products ◽  
Scope Of Application

Introduction. In the Russian pharmaceutical market, there is the following situation: herbal medicinal products (HMP) and dietary supplements based on plant raw materials (DS) have similar compositions, dosage forms and scope of application. They’re often considered analogues by consumers and specialists, which indicates the existence of common market for these products.Research aim is to investigate the state and development trends of the Russian HMP and DS market, assessing positions of foreign and domestic companies and general prospects for this market as well.Methodology. The study was conducted using IQVIA retail audit database, official sources of information on HMP and DS registration. In the market analysis the products were classified depending on the scope of application, composition and preparation methods, and dosage forms as well.Results. In 2020 pharmacy of HMP and DS sales amounted to 435.4 million units valued at 51.3 billion rubles in wholesale prices. Beginning with 2016, the average annual growth rate corresponded to 4.2%, in value terms. However, in volume terms, the sales were reduced in the average by 3.4% per year (due to cheap domestic medicines). The main part of the entire market comprises HMP (80% in units and 74% in value terms in 2020). The products, affecting respiratory system, genitourinary sphere, and digestion, provide more than three-quarters of all sales in value terms. More than half of the market is occupied by total extractive drugs. Solid dosage forms (tablets and capsules) account for half of the sales, plant raw materials and fees constitute more than one third. In 2020, Russian companies provided 28% of the sales of HMP and 67% of DS in value terms. In the context of the main segments, the market structure in 2016-2020 remained fairly stable.Conclusion. In the future, the market dynamics in value terms will be determined considering by household income and the epidemiological situation. In units, HMP sales will continue to decline through the unprofitable positions of the traditional domestic drug assortment. The increasing strictness of legislation requirements for the market of dietary supplements may contribute to investment in the development of HMP that are competitive to foreign products in terms of quality and consumer characteristics.

scholarly journals Comparison of pharmacological activity of hawthorn fruits preparations

2020 ◽  
Vol 5 (2) ◽  
pp. 136-139
Author(s):  
Vladimir A. Kurkin ◽  
Elena N. Zaitceva ◽  
Elena V. Avdeeva ◽  
Viktoriya V. Stenyaeva ◽  
Ilnur Kh. Shaikhutdinov ◽  
...  
Keyword(s):  
Comparative Study ◽  
Raw Materials ◽  
Antidepressant Activity ◽  
Diuretic Action ◽  
Plant Raw Materials ◽  
Alcohol Water ◽  
Diuretic Agents ◽  
The Comparative Study ◽  
White Mongrel ◽  
Saluretic Activity

Objectives - a comparative study of antidepressant activity and diuretic action of water and water-alcohol preparations of the fruits of Crataegus sanguinea Pall. and Crataegus submollis Sarg. Materials and methods. The study covers the water and alcohol-water extracts from the fruits of hawthorn blood-red (Crataegus sanguinea Pall.) and Quebec hawthorn (Crataegus submollis Sarg.). The comparative study of the antidepressant activity and the diuretic action of the preparations was carried out on white mongrel rats of both sexes. Results. The liquid extracts of fruits Crataegus sanguinea Pall. and Crataegus submollis Sarg. at a dose of 100 μl/kg revealed an antidepressant activity. Decoctions of Crataegus sanguinea Pall. and Crataegus submollis Sarg. at a dose of 100 μl/kg had a pronounced diuretic and saluretic activity. Pharmacotherapeutic effects of the studied preparations can be explained by the presence of flavonoids in them. Conclusion. The preparations of the fruits of Crataegus sanguinea Pall. and Crataegus submollis Sarg. can be recommended as antidepressant and diuretic agents. The fruits of Crataegus submollis Sarg. are the promising medicinal plant raw materials.

STUDY OF DIURETIC AND ANTI-INFLAMMATORY ACTIVITY OF INFUSION AND EXTRACT OF DRIED STRAWBERRY LEAVES

2021 ◽  
pp. 136-142
Author(s):  
Yaborova O.V. ◽  
Sosnina S.A. ◽  
Turyshev A.Yu.
Keyword(s):  
Medicinal Plant ◽  
Medical Practice ◽  
Raw Materials ◽  
Practical Interest ◽  
Biologically Active ◽  
Inflammatory Activity ◽  
Plant Raw Materials ◽  
Wild Strawberry ◽  
Anti Inflammatory ◽  
Wild Strawberries

The search for new sources of medicinal plant raw materials for the production of drugs is one of the urgent tasks of modern pharmacy. The expansion of the range of medicinal plant raw materials is possible, first of all, due to the types systematically close to the official ones. In medical practice, wild strawberry leaves are used. Wild strawberry leaves are used in medicine as a diuretic, anti-inflammatory, antispasmodic, choleretic, hypoglycemic, antipyretic, hypolipidemic, antimicrobial and appetite-enhancing agent. Earlier studies of strawberry leaves have shown that they have a rich chemical composition and are widely cultivated in Russia, being an affordable source for mass procurement of raw materials, and are not used in scientific medicine. At the same time, in folk medicine, strawberry garden leaves are used similarly, and sometimes instead of wild strawberries. The proximity of the composition of biologically active substances of wild strawberries and garden strawberries. To expand the modern nomenclature of medicines, studies on the comparative study of the toxicity and pharmacological activity of infusions and extraction forms from medicinal plant raw materials of strawberry leaves are relevant. In this regard, the study of the toxicity, diuretic and anti-inflammatory activity of the infusion of garden strawberry leaves and the extract of dry strawberry leaves is of practical interest for the formation of a scientific justification for their use in medical practice.

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