O empirycznych przesłankach pluralizmu bytowego

2006 ◽  
Vol 11 (1) ◽  
pp. 37-53
Author(s):  
Piotr Lenartowicz

The sciences, from their ancient beginnings, use a double way of investigation. One was applied to mineral and astronomical bodies, another to living ones. A ruling, tacit, common sense methodological or epistemological principle was this: The method of description should respect the inner essential properties of the object. For instance, neither the movements of the astronomical bodies, nor the behavior of the living bodies should be described in the scale of subatomic interactions. In modern times quite another methodological principle has been enthroned. The cosmos, astronomical, mineral and alive bodies altogether, have, allegedly, to be considered as a single natural whole, ruled by essentially the same set of principles. The properties of the mineral world are accepted as a universal model of descriptive concepts, and the explanatory concepts proper to the mineral world are accepted as a universal model of explanation in biology. So, up to now, the academic sciences have been dominated by the philosophical option of materialist monism, or panmaterialism. This option—we may call it antiteleologism and fragmentarism—has a profound impact on empirical research and the way biological phenomena are described. This strange, unnatural, arbitrarily imposed conceptual framework ignores the most fundamental biological dynamisms, and precludes our intellect from seeing the right questions and striving towards the right answers. Consequently it arbitrarily reduces the range of “scientifically acceptable” explanations. This antiteleological methodology of sciences, imposed on biological mind by philosophers, led to major change in the ideas of philosophers of nature. The physiology and anatomy of the fully developed living bodies has become their central object of study. Much less attention is paid to developmental processes such as biosynthesis, morphogenesis, embryogenesis, phenotypic adaptation and regeneration. The fully shaped structures (biomolecular, cytological or anatomical) and their functional properties are considered a hopeful basis of all the necessary explanations. For instance the structure of tile DNA molecule has become more important than the problem of its origin, and the structure of the brain more important than the developmental processes which lead to its construction. However, the enormous progress of biological sciences in spite of the widespread, dominating antiteleological and fragmentarist approach corroborates the very ancient, Aristotelian insight, which put the principal stress on the developmental aspect of life. Aristotle, and his more modern followers, was fascinated by the integrated and intrinsically heterogenous tendencies visible in the course of life. Today, we can say that at least eight such tendencies are universal, i.e. appear in every single form of life (starting with bacteria tip to the biology of man): (a) The tendency to select the proper kind of raw material and the proper kind of raw energy present in the environment. (b) The tendency to synthesize new, highly selective forms of chemical structures (biological material). (c) The tendency to utilize biological material in the process of building the nano-, micro-, and macro-machines. (d) The tendency for a relatively rapid, continuous production and replacement of all the elements of the functional structures of the body (metabolic turnover). (e) The tendency for a relatively rapid, continuous modification of the functional structures in a way which makes them more efficient within a changing environment (a tendency for phenotypic adaptation). (f) The tendency to repair and to regenerate the damaged elements of the functional structures of the body. (g) The tendency for multiplication, which means the production of such structures and the depots of the biological material as seeds, eggs, spores or buds. These structures, providing the environmental conditions are favorable, are starting points of new instances of the above described tendencies. (h) The tendency—possibly universal—to provide all the structures of the body with the “recognition marks” which help to eliminate all the, “alien” bodies and to recognize members of the own kind. These tendencies are not homogeneous. Homogeneous tendencies can be illustrated by the tendency of bodies to attract one another. This kind of tendency was the empirical source of such abstract concepts as gravitation, electrostatic force or magnetic force. Biological tendencies are heterogeneous and, at the same time, integrated. Human intellect is capable of recognizing the fundamental indivisibility (integration) of the set. A great number of observations and experiments have revealed and verified the fundamental indivisibility of the whole set of these tendencies. The concrete, bodily outcomes of these tendencies, however, are quite different in different families and orders of living things. Because of these differences the existence of different kinds of integrative principles was postulated. In this way a plurality of living substances was assumed.

1971 ◽  
Vol 179 (1057) ◽  
pp. 345-355 ◽  

The group of antibiotics known as the penicillins have a unique position in chemistry. Not only were they the first type of antibiotic to be widely accepted in medical practice, but their manufacture provided a powerful stimulant for the growth of the pharmaceutical industry. Furthermore, they still represent the most important and widely dispensed group of antibiotics in current use (Hewitt 1967). Several thousand tons of the penicillins are produced annually. Modern production methods have reduced the cost to a few pence per gram. As a consequence one should now regard the penicillins as a potentially useful raw material, suitable as a starting-point for the synthesis of a variety of derivatives. As an example one may quote the use of penicillins as precursors for the syn­thesis of the related, very useful antibiotics, the cephalosporins. The penam 1 and cephem 2 systems have similar chemical structures notable in possessing the identical β-lactam grouping 3 and the same C 5 isoprenoid-like unit [to the right of the dotted lines in 1 and 2.] The systems differ in that the cephalosporins possess a higher oxidation level than the penicillins and a different substitution pattern on the C 5 unit.


Author(s):  
Irina ROMAN ◽  
Cristian MARTONOS ◽  
Cristian MARTONOS ◽  
Cristian DEZDROBITU ◽  
Cristian DEZDROBITU ◽  
...  

In birds, in contrast to mammals, two brachiocephalic trunks are the origin in the arch of aorta and give rise to the subclavian arteries and common carotid. The aim of this study was to investigate the vascular branching morphology of the aortic arch in Gallus Domesticus with the purpose of providing accurate data with regards to the arterial supply of these segments to researchers and clinicians. The biological material was represented by 10 adult chicken bodies with an average weight of 2 kg, females. After procurement of the biological material, the feathers, skin, muscles and sternum were removed for easy access to the heart. After left ventricular cannulation, epoxy resin mixed with red dye was injected. The body was immersed in 5% formaldehyde for 24 hours. Next, stratigraphic dissection was performed. Two brachiocephalic trunks branched continually from aortic arch caudoventral to the primary bronchi. The left subclavian artery gave rise to sternoclavicular, thoracic, axillary and intercostal and the same was observed to the right side. Due to this method we could observe the aortic arch of Gallus Domesticus being different from mammals in that the left and right brachiocephalic trunks are detached from it.


Author(s):  
Anne Phillips

No one wants to be treated like an object, regarded as an item of property, or put up for sale. Yet many people frame personal autonomy in terms of self-ownership, representing themselves as property owners with the right to do as they wish with their bodies. Others do not use the language of property, but are similarly insistent on the rights of free individuals to decide for themselves whether to engage in commercial transactions for sex, reproduction, or organ sales. Drawing on analyses of rape, surrogacy, and markets in human organs, this book challenges notions of freedom based on ownership of our bodies and argues against the normalization of markets in bodily services and parts. The book explores the risks associated with metaphors of property and the reasons why the commodification of the body remains problematic. The book asks what is wrong with thinking of oneself as the owner of one's body? What is wrong with making our bodies available for rent or sale? What, if anything, is the difference between markets in sex, reproduction, or human body parts, and the other markets we commonly applaud? The book contends that body markets occupy the outer edges of a continuum that is, in some way, a feature of all labor markets. But it also emphasizes that we all have bodies, and considers the implications of this otherwise banal fact for equality. Bodies remind us of shared vulnerability, alerting us to the common experience of living as embodied beings in the same world. Examining the complex issue of body exceptionalism, the book demonstrates that treating the body as property makes human equality harder to comprehend.


2013 ◽  
Vol 7 (1) ◽  
pp. 7
Author(s):  
Doni Budiono

The  authority  of justice in Indonesia  is executed by  the Supreme Courts and  the  justice  boards/body under the Supreme Courts, including  the general  justice, religious affairs justice, military justice,  state administration  justice,  and  the Constitution Court. According to  certainty in  the Act of  Tax Court, Article1, clause  (5),  tax  dispute   refers to the legal dispute arising in the  taxation  affairs between the  tax payer or the  body  responsible for the  tax with   the government   executives  ( Directorate General of Tax) as the consequence of   the issue of  the decree for the  appeal  to the Tax  Court in accordance with the  tax Act, including the  charge  against the  execution of collection   in accordance with the  Act of Tax Collection by force. The  formation of Tax Court is  designed by  the Executives, in this case, the  Department of Finance, specifically  the Directorate   General  of Tax  which has the right to issue  law  more technical about  tax accord to Article 14,  letter A,  President Decree  no. 44  year 1974,  concerning the  basic  organization of the Department.  Based on  it,  it  is clear that  in addition to execute the government  rules and policy,  this body  has to execute judicial   rules and policy. This is against the  principles of  Judicative  Power/Authority in Indonesia,  which   clearly states that this body  should be under the Supreme Court.   Therefore. It is suggested that   the Act  No UU no.14 Year 2012 concerning  Tax Court   be revised  in accordance with the system of  Power Division  of Justice  as  stated in 45 Constitutions.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1477-1481
Author(s):  
Ishwari Gaikwad ◽  
Priyanka Shelotkar

The current world situation is both frightening and alarming due to the massive disruption caused by the Covid-19 pandemic. The next few days are censorious as we need to be very precautious in our daily regimen as well as dietary habits. Ayurveda offers knowledge about food based on certain reasoning. Indecent food custom is the chief cause for the rising development of health disorders in the current era. In classical texts of Ayurveda, the concept of diet explained well, ranging from their natural sources, properties and specific utility in pathological as well as physiological manner. In this work, the review of the relevant literature of Ahara (Diet) was carried out from Charak Samhita and other texts, newspapers, articles, web page related to the same.  Every human being is unique with respect to his Prakriti (Physical and mental temperament), Agni (Digestive capacity), Koshtha  (Nature of bowel) etc. For that reason, the specificity of the individual should be kept in mind. Ahara, when consumed in the appropriate amount at the right moment following all Niyamas (Guidelines) given in Ayurveda texts, gives immunity and keeps the body in a healthy state during pandemics such as Covid-19. Ultimately, this will help the human body to maintain its strength for life. This article reviews the concept of diet viz. combination of foods, their quantity and quality, methods of preparation and processing, which are to be followed during pandemics and are essential in maintenance and endorsement of health and preclusion of diseases.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 832-838
Author(s):  
Roshna Sukheoji Bhutada ◽  
Renu Rathi ◽  
Devyani Dasar

WHO declared Covid 19 /SARS -COV-2 as a global pandemic.Till date, there is no medicine for COVID-19. If the Infection arises in the body then the defence mechanism activated against infection. A recent study suggests that temporarily augmenting the body's immune system in the early stages of COVID-19 can help patient to avoid severe symptoms as it is rightly said prevention is better than cure. Ayurveda approaches to develop physiological reactions to facilitate immunity. Planning of diet is most important to boost immunity.As per many researches to provide supplementary food which contains Zinc, Vitamin C,Vitamin D and immunity boosting foodsuch as citrus natural products, custard apple, apple, papaya is among the Fruits. Vegetables include broccoli, onion, garlic and green leafy vegetables. Nuts, ginger, turmeric, pepper, egg yolk, shellfish, mushroom. The need of the hour is a quick boost to immune system to keep it fit, fighting. One should get the right amount of nutrients from the diet, supplementation regimen to boost immune system.In this review, there are few common supplements and super food studies have been included. It might be a torch bearer as sample menu and their alternatives are given for a normal adult. Needy may change contemplated according to age, sex, body mass index and daily physical activities.


Author(s):  
Siraj Salman Mohammad ◽  
Renata Oliveira Santos ◽  
Maria Ivone Barbosa ◽  
José Lucena Barbosa Junior

: Anthocyanins are widely spread in different kinds of food, especially fruits and floral tissues, there is an extensive range of anthocyanin compounds reach more than 600 exist in nature. Anthocyanins can be used as antioxidants and raw material for several applications in food and pharmaceutical industry. Consequently, a plenty of studies about anthocyanins sources and extraction methods were reported. Furthermore, many studies about their stability, bioactive and therapeutic properties have been done. According to the body of work, we firstly worked to shed light on anthocyanin properties including chemical, antioxidant and extraction properties. Secondly, we reported the applications and health benefits of anthocyanin including the applications in food processes and anthocyanin characteristics as therapeutic and prophylactic compounds. We reviewed anticancer, anti-diabetic, anti-fatness, oxidative Stress and lipid decreasing and vasoprotective effects of anthocyanins. In conclusion, because the importance of phytochemicals and bioactive compounds the research is still continuing to find new anthocyanins from natural sources and invest them as raw materials in the pharmaceutical and nutrition applications.


Impact ◽  
2018 ◽  
Vol 2018 (3) ◽  
pp. 26-28
Author(s):  
Jonathan Dawson ◽  
Richard Oreffo

Gels made from clay could provide an environment able to stimulate stem-cells due to their ability to bind biological molecules. That molecules stick to clay has been known by scientists since the 1960s. Doctors observed that absorption into the blood stream of certain drugs was severely reduced when patients were also receiving clay-based antacid or anti-diarrhoeal treatments. This curious phenomenon was realized to be due to binding of the drugs by clay particles. This interaction is now routinely harnessed in the design of tablets to carefully control the release and action of a drug. Dr Dawson now proposes to use this property of clay to create micro-environments that could stimulate stem cells to regenerate damaged tissues such as bone, cartilage or skin. The rich electrostatic properties of nano (1 millionth of a millimetre) -scale clay particles which mediate these interactions could allow two hurdles facing the development of stem-cell based regenerative therapies to be overcome simultaneously. The first challenge - to deliver and hold stem cells at the right location in the body - is met by the ability of clays to self-organise into gels via the electrostatic interactions of the particles with each other. Cells mixed with a low concentration (less than 4%) of clay particles can be injected into the body and held in the right place by the gel, eliminating, in many situations, the need for surgery. Clay particles can also interact with large structural molecules (polymers) which are frequently used in the development of materials (or 'scaffolds'), designed to host stem cells. These interactions can greatly improve the strength of such structures and could be applied to preserve their stability at the site of injury until regeneration is complete. While several gels and scaffold materials have been designed to deliver and hold stem cells at the site of regeneration, the ability of clay nanoparticles to overcome a second critical hurdle facing stem-cell therapy is what makes them especially exciting. Essential to directing the activity of stem-cells is the carefully controlled provision of key biological signalling molecules. However, the open structures of conventional scaffolds or gels, while essential for the diffusion of nutrients to the cells, means their ability to hold the signalling molecules in the same location as the cells is limited. The ability of clay nano-particles to bind biological molecules presents a unique opportunity to create local environments at a site of injury or disease that can stimulate and control stem-cell driven repair. Dr Dawson's early studies investigated the ability of clay gels to stimulate the growth of new blood vessels by incorporating a key molecular signal that stimulates this process, vascular endothelial growth factor (VEGF). In a manner reminiscent of the observations made in the 60s, Dr Dawson and colleagues observed that adding a drop of clay gel to a solution containing VEGF caused, after a few hours, the disappearance of VEGF from the solution as it became bound to the gel. When placed in an experimental injury model, the gel-bound VEGF stimulated a cluster of new blood vessels to form. These exciting results indicate the potential of clay nanoparticles to create tailor-made micro-environments to foster stem cell regeneration. Dr Dawson is developing this approach as a means of first exploring the biological signals necessary to successfully control stem cell behaviour for regeneration and then, using the same approach, to provide stem cells with these signals to stimulate regeneration in the body. The project will seek to test this approach to regenerate bone lost to cancer or hip replacement failure. If successful the same technology may be applied to harness stem cells for the treatment of a whole host of different scenarios, from burn victims to those suffering with diabetes or Parkinson's.


2021 ◽  
pp. 1-20
Author(s):  
Benjamin Hegarty

The regulation of public space is generative of new approaches to gender nonconformity. In 1968 in Jakarta, the capital of Indonesia, a group of people who identified as wadam—a new term made by combining parts of Indonesian words denoting “femininity” and “masculinity”—made a claim to the city's governor that they had the right to appear in public space. This article illustrates the paradoxical achievement of obtaining recognition on terms constituted through public nuisance regulations governing access to and movement through space. The origins and diffuse effects of recognition achieved by those who identified as wadam and, a decade later, waria facilitated the partial recognition of a status that was legal but nonconforming. This possibility emerged out of city-level innovations and historical conceptualizations of the body in Indonesia. Attending to the way that gender nonconformity was folded into existing methods of codifying space at the scale of the city reflects a broader anxiety over who can enter public space and on what basis. Considering a concern for struggles to contend with nonconformity on spatial grounds at the level of the city encourages an alternative perspective on the emergence of gender and sexual morality as a definitive feature of national belonging in Indonesia and elsewhere.


Children ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 288
Author(s):  
Wojciech Rusek ◽  
Joanna Baran ◽  
Justyna Leszczak ◽  
Marzena Adamczyk ◽  
Rafał Baran ◽  
...  

The main goal of our study was to determine how the age of children, puberty and anthropometric parameters affect the formation of body composition and faulty body posture development in children. The secondary goal was to determine in which body segments abnormalities most often occur and how gender differentiates the occurrence of adverse changes in children’s body posture and body composition during puberty. The study group consisted of 464 schoolchildren aged from 6–16. Body posture was assessed with the Zebris system. The composition of the body mass was tested with Tanita MC 780 MA body mass analyzer and the body height was measured using a portable stadiometer PORTSTAND 210. The participants were further divided due to the age of puberty. Tanner division was adopted. The cut-off age for girls is ≥10 years and for boys it is ≥12 years. The analyses applied descriptive statistics, the Pearson correlation, stepwise regression analysis and the t-test. The accepted level of significance was p < 0.05. The pelvic obliquity was lower in older children (beta = −0.15). We also see that age played a significant role in the difference in the height of the right pelvis (beta = −0.28), and the difference in the height of the right shoulder (beta = 0.23). Regression analysis showed that the content of adipose tissue (FAT%) increased with body mass index (BMI) and decreased with increasing weight, age, and height. Moreover, the FAT% was lower in boys than in girls (beta negative equal to −0.39). It turned out that older children (puberty), had greater asymmetry in the right shoulder blade (p < 0.001) and right shoulder (p = 0.003). On the other hand, younger children (who were still before puberty) had greater anomalies in the left trunk inclination (p = 0.048) as well as in the pelvic obliquity (p = 0.008). Girls in puberty were characterized by greater asymmetry on the right side, including the shoulders (p = 0.001), the scapula (p = 0.001) and the pelvis (p < 0.001). In boys, the problem related only to the asymmetry of the shoulder blades (p < 0.001). Girls were characterized by a greater increase in adipose tissue and boys by muscle tissue. Significant differences also appeared in the body posture of the examined children. Greater asymmetry within scapulas and shoulders were seen in children during puberty. Therefore, a growing child should be closely monitored to protect them from the adverse consequences of poor posture or excessive accumulation of adipose tissue in the body.


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