scholarly journals Hubungan Kadar Interleukin 10 Serum dan Klasifikasi CT Marshall pada Pasien Cedera Otak Berat akibat Trauma

2019 ◽  
Vol 11 (2) ◽  
pp. 97
Author(s):  
Melina O. Kurniawan ◽  
Eko Prasetyo ◽  
Maximillian Ch. Oley

Abstract: Increased level of interleukin 10 (IL 10) in patients with severe traumatic brain injury (TBI) has been documented, yet studies of its ability to predict the outcome based on the Marshall CT classification are still limited and lacks of clarity. This study was aimed to evaluate the relationship between serum level of IL 10 and the Marshall CT classification among patients with severe TBI. This was an analytical observational single-center study with a cross-sectional design. Immediate CT scans were used to determine the Marshall CT classification and to categorize the location (extra-axial, intra-axial, both), hemisphere (midline/diffuse, dextral, sinistral), and area (frontal, parietal, temporal, occipital, multiple) of the injury. Venous blood sample for IL 10 was taken less than 24 hours of trauma in the Intensive Care Unit. Age and gender were also recorded. Variable selection was run in stepwise forward fashion. Proportional odds models were conducted to assess the changes in the Marshall CT classification related to levels of IL 10. There were 25 patients admitted consecutively to the emergency room (ER) with severe TBI included in this study. The results showed that the mean IL 10 was 107.3 pg/ml (SD 16.2 pg/ml). Patients were distributed almost uniformly within four detected categories (diffuse injury II, III, V, and VI) of the CT Marshall classification. Final regression model consisted of IL 10, age, and injury on temporal area as predictors. Controlling for the others, every 10 pg/ml additional of IL 10 increased the odds to higher (worse) categories in the CT Marshall classification by about 1.95 (95% CI 1.16 – 3.30) times. Conclusion: Interleukin 10 is a potential predictor for the CT Marshall classification in patients with severe TBI.Keywords: IL 10, Marshall CT classification, TBIAbstrak: Peningkatan kadar serum interleukin 10 (IL 10) pada pasien dengan cedera otak traumatik (COT) berat telah didokumentasikan, namun studi tentang kemampuannya untuk memrediksi hasil berdasarkan klasifikasi CT Marshall masih terbatas dan belum jelas. Penelitian ini bertujuan untuk mengevaluasi hubungan antara kadar serum IL 10 dan klasifikasi CT Marshall pada pasien COT berat. Jenis penelitian ialah observasional analitik dengan desain potong lintang. CT scan digunakan untuk menentukan klasifikasi CT Marshall dan untuk mengategorikan lokasi (ekstra-aksial, intra-aksial, keduanya), hemisfer (garis tengah/ difus, dekstra, sinistra), dan area (frontal, parietal, temporal, oksipital, multipel) otak yang terkena cedera. Sampel darah vena untuk IL 10 diambil kurang dari 24 jam pasca trauma. Usia dan jenis kelamin juga dicatat. Seleksi variabel dilakukan secara bertahap. Digunakan model regresi proporsional odds untuk menilai perubahan klasifikasi CT Marshall terkait dengan kadar IL 10. Hasil penelitian mendapatkan 25 pasien dengan COT berat yang masuk ke Instalasi Rawat Darurat Bedah (IRDB). Rerata IL 10 ialah 107,3 pg/ml (SD 16,2 pg/ml). Pasien didistribusikan hampir seragam dalam empat kategori (cedera difus II, III, V, dan VI) dari klasifikasi CT Marshall. Model regresi akhir terdiri dari IL 10, usia, dan cedera pada area temporal sebagai prediktor. Sebagai kontrol, setiap peningkatan IL 10 sebanyak 10 pg/ml meningkatkan kemungkinan klasifikasi CT Marshall yang lebih tinggi (lebih buruk) sekitar 1,95 (95% CI 1,16-3,30) kali lebih tinggi. Simpulan: IL10 merupakan prediktor potensial untuk klasifikasi CT Marshall pada pasien dengan COT berat. Kata kunci: IL 10, klasifikasi CT Marshall, COT

2019 ◽  
Vol 11 (1) ◽  
pp. 47
Author(s):  
David Loing ◽  
Eko Prasetyo ◽  
Maxmillian Ch. Oley

Abstract: Serum level of interleukin 10 (IL-10) and the FOUR score have both been suggested as predictors for the outcomes after severe traumatic brain injury (TBI). Studies are limited, however, on how they are related to each other. This study was aimed to assess the relationship between serum level of IL-10 and the FOUR score in patients with severe TBI. This was an observational study with a cross sectional design. The study was conducted on 25 severe TBI patients with FOUR score of 0-14 consecutively admitted at the the Emergency Surgery Installation of Prof. Dr. R. D. Kandou Hospital. Classification of the hemorrhage location (extra-axial, intra-axial, both), hemisphere (midline/diffuse, dextral, sinistral), and area (frontal, parietal, temporal, occipital, multiple) was established by using CT scans. Venous blood sample for IL 10 was performed less than 24 hours after trauma. Binary logistic regression was used to model the relationship of interest, with covariates selected through stepwise forward selection. The results obtained 25 patients dominated by males (84%), with median age 31. Mean IL-10 was 107.3 pg/ml (SD 16.2 pg/ml). Median FOUR score was 10, with fairly equal proportion in the category of high (FOUR score 0-7; 48%) and moderate (FOUR score 8-14; 52%) mortality risks. Final regression model included age and injury on temporal area (yes, no) as covariates for IL-10. Adjusting for these variables, the average patients had about 1.12 (95% CI 1.01, 1.25) times higher odds for worse FOUR scores (0-7, high mortality risk) in each pg/ml addition of serum IL-10. Conclusion: The finding indicates that increased IL-10 level is a potential alternative to the lower FOUR score for predicting worse outcome in patients with severe TBI.Keywords: IL-10; FOUR score; TBIAbstrak: Interleukin 10 (IL-10) serum dan skor FOUR disarankan sebagai prediktor luaran setelah cedera otak akibat trauma (COT) berat namun penelitian mengenai hubungan keduanya masih terbatas. Penelitian ini bertujuan untuk menilai hubungan antara kadar IL-10 serum dan skor FOUR pada pasien dengan COT berat. Jenis penelitian ialah observasional dengan desain potong lintang. Penelitian dilaksanakan pada 25 pasien dengan COT berat dan skor FOUR 0-14 secara berurut masuk ke UGD Prof. Dr. R. D. Kandou. Klasifikasi lokasi perdarahan (ekstra-aksial, intra-aksial, keduanya), hemisfer (garis tengah/difus, dekstra, sinistra), dan area (frontal, parietal, temporal, oksipital, multipel) ditetapkan dengan CT scan. Sampel darah vena untuk pemeriksaan IL-10 diambil kurang dari 24 jam setelah trauma. Regresi logistik biner digunakan pada model untuk hubungan ketertarikan dan kovariat stepwise forward. Hasil penelitian mendapatkan 25 pasien didominasi oleh laki-laki (84%), median usia 31 tahun. Rerata IL-10 107,3 pg/ml (SD 16,2 pg/ml). Median skor FOUR 10 dengan proporsi berimbang pada kategori tinggi (skor FOUR 0-7; 48%) dan sedang (skor FOUR 8-14; 52%) risiko mortalitas. Model regresi akhir termasuk usia dan cedera area temporal (ya, tidak) sebagai kovariat untuk IL-10. Rata-rata pasien memiliki sekitar 1,12 (95% CI 1,01-1,25) kali peluang lebih tinggi untuk skor FOUR yang lebih buruk (0-7, risiko kematian tinggi) pada setiap peningkatan 1 pg/ml kadar IL-10 serum. Simpulan: Temuan ini menunjukkan peningkatan IL-10 sebagai alternatif potensial terhadap skor FOUR yang lebih rendah untuk memrediksi hasil yang lebih buruk pada pasien dengan COT berat.Kata kunci: IL-10, skor FOUR, COT


2019 ◽  
Vol 11 (1) ◽  
pp. 41
Author(s):  
Mervin Manginte ◽  
Eko Prasetyo ◽  
Maximillian Ch. Oley

Abstract: Increase of interleukin 6 (IL-6) level occurs in the brain after traumatic brain injury (TBI), however, studies about IL-6 as a prodictor based on CT-scan is still limited. This study was aimed to evaluate the relationship between serum IL-6 level and CT Marshall classification in patients with severe TBI. This was an observational study with a cross sectional design. There were 20 patients with severe TBI admitted at the Emergency Surgery Installation of Prof. Dr. R. D. Kandou Hospital Manado in this study. CT-scan was performed on them to determine the CT Marshall classification and to categorize the hemorrhage location (extra-axial, intra-axial, both), hemisphere (midline/diffuse, dextral, sinistral), and area (frontal, parietal, temporal, occipital, multiple). Venous blood sample used for IL-6 examination was drawn less than 24 hours after trauma. The results showed that mean IL-6 level was 22.0060 pg/mL (SD 4.64494 pg/mL). Patients were distributed relatively uniform in 4 detected categories (diffuse injury II, III, V, and VI) of CT Marshall classification. Final regression model consisted of IL-6, age, and temporal injury as predictors. The Spearman coefficient correlation showed rs = -0.005 (P=0.491). Conclusion: There was no significant relationship between serum Il-6 level and CT Marshall classification, albeit, both of them increased consistantly following the severity of TBI and could be potential predictors to determine the prognosis of severe TBI patients.Keywords: IL-6, CT Marshall, severe TBIAbstrak: Pada cedera otak berat akibat trauma (COBT) terjadi peningkatan ekspresi IL-6 di otak namun penelitian mengenai kemampuannya untuk memrediksi hasil berdasarkan klasifikasi CT scan masih terbatas. Penelitian ini bertujuan untuk mengevaluasi hubungan antara kadar IL-6 serum dan klasifikasi CT Marshall pada pasien dengan COBT. Jenis penelitian ialah observasional dengan desain potong lintang. Hasil penelitian mendapatkan 20 pasien yang dirawat dengan COBT di IRDB RSUP Prof. Dr. R. D. Kandou Manado. CT-scan segera digunakan untuk menentukan klasifikasi CT Marshall dan untuk mengategorikan lokasi (ekstra-aksial, intra-aksial, keduanya), belahan (garis tengah/difus, dekstra, sisnitra), dan area otak yang terlibat dalam cedera. Sampel darah vena untuk IL-6 diambil kurang dari 24 jam setelah trauma. Hasil penelitian mendapatkan rerata kadar IL-6 22,0060 pg/mL (SD 4,64494 pg/mL). Pasien didistribusikan relatif seragam dalam empat kategori yang terdeteksi (difus cedera II, III, V, dan VI) dari klasifikasi CT Marshall. Model regresi akhir terdiri dari IL-6, usia, dan cedera pada area temporal sebagai prediktor. Korelasi antara kadar IL-6 serum dan klasifikasi CT Marshall dianalisis dengan koefisien korelasi Spearman dan mendapatkan rs = -0,005 (P=0,491). Simpulan: Walaupun secara statistik tidak terdapat hubungan bermakna antara kadar Il-6 serum dan CT Marshall namun keduanya secara konsisten meningkat mengikuti COBT dan dapat menjadi prediktor potensial untuk menentukan prognosis pada pasien dengan COBT.Kata kunci: IL-6, CT Marshall, COBT


2019 ◽  
Vol 4 (1) ◽  
pp. 41-49
Author(s):  
Meriati Bunga Arta Purba

Based on the research by the Sexuality and Gender Study Center of University of Indonesia, the rate of early marriage in Indonesia is the second highest in Southeast Asian in which 2 million out of 7.3 million women below 15 years old are married and drop out from school. Early marriage hinders them from going to school, causes pregnancy and birth complication, impedes the achievement of KB (Family Planning) Program and increases divorce rate. Goals : The objective of the research was to discover the correlation of value of virginity, knowledge and trust with early marriage at Dusun I Desa Baru. Methods: This is an observational analytical research with cross sectional design. It was done at Dusun I Desa Baru, Pancur Batu Subdistrict from November, 2017 until February, 2018. The population covered the teenagers below 20 years old which was all taken as the research samples i.e. 139 people. The dependent variable was early marriage, while the independent variables were parent income, trust, knowledge and value of virginity. The data were collected through questionnaires. Multiple logistic regression testing was employed to analyze the data. Result : The research results demonstrated that the variable with the most dominant influence was parent income at p-value = 0.006 (p<0.05) and Exp. β value = 3.675, followed by the variable of trust at p-value = 0.027 (p<0.05) and Exp. β value = 2.368, the variable of knowledge at p-value = 0.003 (p<0.05) and Exp. β value 6.064, and the variable of virginity at p-value = 0.003 (p<0.05) and Exp. Β value = 6.064. Based on these results, it was concluded that f(y) was 97%. It indicated that the probability of the variables of parent income, trust, knowledge and virginity influenced early marriage of 97.7%. Conclusion: It is recommended that the local government cooperate with local Puskesmas, Religious Figures, and Parents to conduct counseling to improve people’s knowledge of the ideal age to get married, so that they can prevent from possible problems due to early marriage and provide their children parent income at early age the importance of protecting their virginity until they get married.


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Marianne C. Jacobus ◽  
Max F.J Mantik ◽  
Adrian . Umboh

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside  Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai


2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Ros Endah Happy Patriyani ◽  
David Ferry Purwanto

Abstract: Risk Factors, CHD. Coronary Heart Disease (CHD) is the coronary atherosclerotic disease that causes narrowing of blood vessels. Constriction of blood vessels occurs because of atherosclerosis or spasm or a combination of both. the risk factors of CHD were divided into two, namely the factors that can not be changed and the factors can be changed. Factors that can not be changed include age, family history and gender. While the factors that can be changed include an increase in serum lipids (hyperlipidemia), personality type, smoking, impaired glucose tolerance (diabetes mellitus), lifestyle is less activity (physical inactivity), psychological stress, and hypertension. The purpose of this study to determine the risk factors that lead to increased incidence of coronary heart disease. The study is an observational analytic epidemiologic approach with cross sectional design with a sample of 40 respondents. The data analysis using logistic regression. The results showed the significant influence of CHD events by a factor of age> 40 years (p = 0.7370, hyperlipidemia (p = 0162), hypertension (p = 0365), smoking (p = 0153), as well as physical inactivity (p = 0535 ). Smoking is a risk factor most dominant effect on the incidence of CHD with OR = 4,500. the case studies are necessary to further research with a number of larger samples and develop variable-varabel to be studied is associated with other behaviors and lifestyles that affect developing CHD.


2018 ◽  
Vol 1 (3) ◽  
pp. 192-199
Author(s):  
Ezra Hans Soputra ◽  
Sadakata Sinulingga ◽  
Subandrate Subandrate

Uric acid is the end product of purine catabolism which is sinthesized especially by the liver and excreted through urinary tract. Increased blood uric acid levels can cause many disease such as gout arthritis, hipertension, and renal disease. Individual with obesity often have lower renal excretion rate and may have increased production of uric acid. This study is conducted to determine the relationship of obesity and blood uric acid levels.This Study with cross-sectional design took a sample of 119 students of Medical Education Program Study at Medical Faculty of the Sriwijaya University by consecutive sampling. Body weight, body height, and uric acid levels then are taken using measurement tools appropriate, categorized, and processed according to research objectivesThe study found that 27,5% female and 10,3% male have hyperuricemia. A total of 39,3% obese students and 16,5% non-obese students have high level of uric acid. The result of bivariate analysis showed that there is a significant relationship between obesity and gender with blood uric acid levels (p=0,022 and 0,035 respectively). After multivariate analysis, factor that has relationship with uric acid level is obesity.Obesity have a significant relationship with uric acid levels.


Author(s):  
Sameer A. Alkubati ◽  
Sultan A. M. Saghir ◽  
Khaled M. Al-Sayaghi ◽  
Abdullah Alhariri ◽  
Mahmoud Al-Areefi

Abstract Objectives Ventilator-associated pneumonia (VAP) is the most common nosocomial infection in patients requiring mechanical ventilation in intensive care units (ICUs). VAP is associated with delayed extubation, prolonged hospital stays, increased healthcare costs and mortality rates. The aims of this study to evaluate the level of knowledge for the prevention of VAP among healthcare workers (HCWs) in ICUs and to assess their knowledge in relation to their socio-demographic characteristics. Methods A descriptive, cross-sectional design was conducted to assess HCWs’ knowledge of the guidelines for prevention of VAP in the ICUs of public and private hospitals in Hodeida city, Yemen. Around 140 self-administered multiple-choice questionnaires were distributed between April and July 2017. Results A total of 120 (85.6%) HCWs completed questionnaire were obtained (20 physicians, 20 anesthesia technicians and 80 nurses) in this study. The total mean score of the HCWs’ knowledge was low (41 ± 18). A statistically significant difference was found in the HCWs’ knowledge scores according to their specialties and gender. Anesthesia technicians had the highest knowledge score followed by physicians and nurses (52.2 ± 16.2, 45.6 ± 21.2 and 37.1 ± 16.9, respectively, p=0.002). Males had higher scores than females (Median [IQR] 4 [3–5] vs. 3 [2–4], p<0.001). Participants who received information about the prevention of VAP had better knowledge than those who did not (46.2 ± 17.7 vs. 36.8 ± 17.3, p=0.006). Conclusions HCWs had a low knowledge level of the guidelines for the prevention of VAP, which may affect their practice. HCWs’ knowledge was affected by their previous received information that increases the necessity to provide them with regular in-service education and training programs.


2019 ◽  
Vol 2 (2) ◽  
pp. 38
Author(s):  
Laga Patriantoro ◽  
Yoga Devaera ◽  
Saptawati Bardosono ◽  
Khalida Fauzia ◽  
Meirina Khoirunnisa ◽  
...  

Background: The prevalence of overweight and obesity in adolescence increases significantly from year to year particularly in Depok. Consumption of sugar-sweetened beverages is one of the causes. Excess triglyceride levels are one of the risk factor for metabolic syndrome and cardiovascular disease. Consumption frequency of sugar-sweetened beverages is associated with increased serum triglyceride levels.  Method: This study used a cross-sectional design involving 47 subjects recruited through the consecutive sampling method. The consumption frequency of sweetened soft drinks is taken by the semiquantitative FFQ method. Samples of serum triglyceride levels were taken from venous blood and measured using enzymatic methods.Result: Forty-seven subjects finished the study protocol The result showed that there is a significant positive correlation with very strong degrees (p = <0.001, r = 0.88) between the consumption frequency of sugar-sweetened beverages with serum triglyceride levels.Conclusion: There is a significant positive correlation with very strong degrees between the consumption frequency of sugar-sweetened beverages with serum triglyceride levels.Keywords: overweight, female adolescence, sugar-sweetened beverages, triglyceride


PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251574
Author(s):  
Rabiul Karim ◽  
Hafijur Rahman ◽  
Suchona Rahman ◽  
Tanzima Zohra Habib ◽  
Katarina Swahnberg

Studies on marital violence (MV) in Bangladesh have primarily focused on the women of the mainstream Bengali people, although half of the population is men, and there are also ethnic minority communities with diverse gender constructions. The current study examined the gender differences in MV among the matrilineal ethnic minority Garo, patrilineal ethnic minority Santal, and the patrilineal mainstream Bengali communities in rural Bangladesh. Adopting a cross-sectional design, we randomly included 1,929 currently married men and women from 24 villages. We used cross-tabulations as well as multivariate logistic regressions to estimate the ethnic and gender differences in MV. Data revealed that women were widely exposed to different types of MV, while only a few men experienced such abuses. It showed that 95.6% of the women experienced emotional abuse, 63.5% physical abuse, 71.4% sexual abuse, and 50.6% poly-victimization, whereas these rates were quite low among the men (emotional = 9.7%, physical = 0.7%, sexual = 0.1%). No men reported poly-victimization. The odds ratio (OR) for emotional, physical, and sexual MV were respectively, 184.44 (95% CI = 93.65−363.24, p<0.001), 449.23 (95% CI = 181.59−1111.35, p<0.001), and 2789.71(95% CI = 381.36−20407.08, p<0.001) for women compared to men. Data further revealed that matrilineal Garo women experienced less MV (emotional = 90.7%, physical = 53.4%, sexual = 64.0%, poly = 38.8%) than the patrilineal Santal (emotional = 99.4%, physical = 67.3%, sexual = 71.3%, poly = 53.9%) and Bengali women (emotional = 96.6%, physical = 69.6%, sexual = 78.8%, poly = 58.9%). Multivariate regressions also showed that the Bengali society perpetrated more physical (OR = 1.90, 95% CI = 1.27−2.85, p = 0.002) and sexual (OR = 2.04, 95% CI = 1.34−3.10, p = 0.001) MV than the Garo society. It appears that MV is largely a gendered issue in the country. Though both women and men can be the victims of MV, the nature/extent of victimization noticeably differs according to the social organization. Matrilineal society appears to be less abusive than the patrilineal one. Interventions aimed to prevent domestic violence in rural Bangladesh should take these findings into account.


2021 ◽  
Vol 13 (1) ◽  
pp. 67-76
Author(s):  
Aryani Pujiyanti ◽  
Arif Suryo Prasetyo ◽  
Wiwik Trapsilowati ◽  
Wening Widjajanti ◽  
Mujiyanto Mujiyanto

Lethal ovitrap is a new alternative in dengue vector control (Aedes spp.) that needs to be socialized to the public. A study of community knowledge and attitudes towards the use of lethal ovitrap as a vector control tool is required as initial data before field application. The purpose of the study was to describe the knowledge and attitudes of the community towards the use of lethal ovitrap before it was applied in the field. An analytical description study with a cross sectional design was conducted in Pulutan Village, Salatiga City. A total of 107 respondents were taken by proportional random sampling to be interviewed. The results showed that 54.30% of respondents had low knowledge and 57.05% of respondents had a less supportive attitude towards the application of lethal ovitrap. In general, the knowledge and attitude of the community towards lethal ovitrap as a vector control tool is still low. Knowledge and gender variables were shown to be significantly related to the supportive attitude given by the community to the application of lethal ovitrap. Education about lethal ovitrap needs to be done before installing lethal ovitrap in the community.   Abstrak Lethal ovitrap merupakan salah satu alternatif baru dalam pengendalian vektor dengue (nyamuk Aedes spp.) yang perlu disosialisasikan ke masyarakat. Studi tentang pengetahuan dan sikap masyarakat terhadap penggunaan lethal ovitrap sebagai alat pengendali vektor diperlukan sebagai data awal sebelum aplikasi lapangan. Tujuan penelitian adalah untuk mendeskripsikan pengetahuan dan sikap masyarakat terhadap penggunaan lethal ovitrap sebelum diaplikasikan di lapangan. Studi deskripsi analitik dengan rancangan cross sectional yang dilakukan di Kelurahan Pulutan, Kota Salatiga. Total 107 responden yang diambil secara proportional random sampling untuk di wawancarai. Hasil penelitian menunjukkan 54,30% responden memiliki pengetahuan rendah dan 57,05% responden memiliki sikap kurang mendukung terhadap aplikasi lethal ovitrap. Secara umum pengetahuan dan sikap masyarakat terhadap lethal ovitrap sebagai alat pengendalian vektor masih rendah. Variabel pengetahuan dan jenis kelamin terbukti secara signifikan berhubungan dengan sikap mendukung yang diberikan masyarakat terhadap aplikasi lethal ovitrap. Edukasi mengenai lethal ovitrap perlu dilakukan sebelum pemasangan lethal ovitrap di masyarakat.


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