ETIOLOGY OF DERMATOPHYTOSIS : A STUDY FROM SOUTH INDIA

2021 ◽  
pp. 20-22
Author(s):  
G Aishwarya Reddy ◽  
Mohammed Abdul Samad ◽  
Karjigi Siddalingappa ◽  
Kallappa C Herakal

BACKGROUND: Dermatophytes are one of the most common fungal agents causing supercial skin infections. The prevalence of these infections varies from place to place and is more commonly associated with low socioeconomic status. AIMS AND OBJECTIVES: To isolate and identify the common dermatophytic species causing the infection and to know the efcacy of the antifungals commonly used against them. METHODS: One hundred and ten new cases, who consented for study were included. Skin scrapings were collected for direct microscopy by KOH and for fungal culture in Sabouraud 4% dextrose agar (SDA) with cycloheximide and dermatophyte test medium. Fungi were identied on the basis of their macroscopic and microscopic features with the help of lactophenol cotton blue staining and urease test. RESULTS: Of the 110 cases, 58 cases were KOH positive for fungal laments and culture positive for dermatophytes. Trichophyton was the predominant isolate (51 cases) with T. verrucosum being the commonest species (28 cases), followed by T. rubrum (16 patients), and T. mentagrophytes (7 cases). All species of Trichophyton were found to be most sensitive to systemic itraconazole and topical luliconazole amongst antifungals. CONCLUSIONS: Trichophyton species is the commonest organism causing fungal infections. Itraconazole and luliconazole are the most effective systemic and topical agents against them.

2016 ◽  
Vol 28 (4) ◽  
pp. 342-347 ◽  
Author(s):  
Alexandra A. García ◽  
Julie A. Zuñiga ◽  
Czarina Lagon

People from non-White racial groups and other underserved populations, including Latinos, are frequently reluctant to participate in research. Yet their participation into research is foundational to producing information that researchers and health care providers need to address health disparities. The purpose of this article is to describe challenges we have encountered along with culturally relevant strategies we used in five research studies to recruit Mexican American participants from community settings, some of whom were also of low socioeconomic status. We found that the most effective recruitment strategies reflect the common cultural values of personalismo, simpátia, confianza, respeto, and familismo.


2020 ◽  
Vol 12 (01) ◽  
pp. 10-14
Author(s):  
Swati Jain ◽  
Sunita Kabi ◽  
Bichitrananda Swain

Abstract Background Dermatophytes are fungi parasitizing structures rich in keratin such as skin, hair, and nail, which leads to a dermal inflammatory response with intense itching and cosmetic disfigurement. The climatic condition of eastern India is predominantly hot and humid with severe rainfalls promoting fungal infection. This study was performed to determine the prevalence of dermatophytosis and to isolate and identify the dermatophyte from clinically suspected cases attending tertiary care center. Methodology This study was conducted from April 2018 to March 2019 and a total of 1,200 samples were included. Skin scrapings were collected and examined microscopically using 10% potassium hydroxide (KOH) mount. Culture was performed using Sabouraud dextrose agar and dermatophyte test medium. Speciation was done based on macroscopic and microscopic findings using lactophenol cotton blue staining and some special tests like urease test and slide culture. Results Of 1,200 cases, tinea corporis was the most common clinical presentation. Direct KOH positivity was 89.4% and culture positivity was 61.75%. Trichophyton mentagrophyte (77.5%) was the most common dermatophyte isolated followed by Trichophyton rubrum (13.3%). Conclusion Dermatophytic infections are not serious but their propensity to persist leading to chronicity and disfigurement may have personal and social implications.


Author(s):  
Shraddha Dalvi Nilma Hirani ◽  
Ritesh Shirpurkar Shrikant G. Joshi ◽  
Abhay Chowdhary Ameeta Joshi

Dermatophytes are keratinophilic fungi responsible for dermatophytoses which are superficial mycoses affecting skin, hair and nails. The aim of the study was to isolate dermatophytes from clinically suspected cases of superficial fungal infections. This study was carried out at the Department of Microbiology, Grant Government Medical College & Sir J.J Group of Hospitals, Mumbai. A total of 279 clinically suspected cases of superficial fungal infections were included in the present study. The specimens like skin scraping, nail and hair were collected with all aseptic precautions and were first examined under microscope on KOH mount and then inoculated on to duplicate slopes of Sabouraud dextrose agar (plain) and SDA (Chloramphenicol and Cycloheximide). Lactophenol cotton blue preparations were made of each fungal growth and were identified using specific tests like slide culture, hair perforation and urease test. Out of the 279 clinically suspected cases of superficial mycoses, maximum involved the skin (65.23%) and a total of 216 (77.42%) cases were of clinically suspected dermatophytoses. KOH mount examination alone could detect 144 (66.66%) cases out of the 216 clinically suspected cases of dermatophytoses. A total 162 isolates were confirmed in which maximum dermatophytes 122 (75.30%) were found. Amongst the dermatophytes, T. rubrum was the commonest pathogenic species isolated followed by T. mentagrophytes. Other species isolated were T. tonsurans, M. gypseum, E. floccosum, T. verrucosum and M. audouinii, T. rubrum and T. mentagrophytes were mainly isolated from Tinea unguium followed by Tinea corporis cases. M. gypseum was isolated only from Tinea capitis cases whereas M. audouinii was isolated only from Tinea unguium cases. Dermatophytoses are the most common types of superficial cutaneous fungal infections. The incidence of Dermatophytoses is increasing in India due to widespread and indiscriminate use of corticosteroids and antifungal agents without performing appropriate microbiological investigations.


2020 ◽  
Vol 48 (7) ◽  
pp. 030006052093162
Author(s):  
Wei Liu ◽  
Ruizhi Feng ◽  
Hongli Jiang

The Scedosporium apiospermum complex is a group of emerging opportunistic fungal pathogens that affect both immunocompromised and immunocompetent individuals, most commonly via lung infection. Although they are resistant to many antifungal agents, this group of pathogens has a favorable susceptibility profile to azoles, especially voriconazole. Here, we describe the management of S. apiospermum infection in an otherwise healthy 44-year-old woman. She had exhibited intermittent hemoptysis for 2 years before admission to our hospital. Computed tomography revealed a thin-walled and well-circumscribed cavitary lesion in the left upper lobe; the lesion was filled with consolidative opacities. Fungal culture of bronchoalveolar lavage fluid specimens revealed grayish-white mold; lactophenol cotton blue staining revealed acute angle branched septate hyaline cylindrical hyphae, characteristic of S. apiospermum. Despite voriconazole 200 mg twice daily for 8 weeks, the patient showed no improvement; thus, her left upper lobe was removed via thoracoscopic surgery. Her symptoms immediately improved and chest radiography after surgical resection showed no evidence of radiological progression or reoccurrence. This report demonstrates that S. apiospermum lung infection may not respond well to voriconazole alone in immunocompetent hosts; thus, surgery could be curative for these patients.


Author(s):  
Prangya Panda ◽  
Bijaya Kumar Sadangi ◽  
Dhaneswari Jena ◽  
Sarita Panda

Background: Rhinosporidiosis is a chronic granulomatous disease. Aim of the study was to do a clinicopathological evaluation of the cases of rhinosporidiosis. Study design was longitudinal.Methods: The study was undertaken in MKCG medical college. 151 cases of rhinosporidiosis were taken. Pedunculated or sessile, fleshy, polypoidal, reddish looking mass with spores on the surface were clinically diagnosed as rhinosporidiosis. Age, sex distribution, site of presentation and socioeconomic status was studied. The swellings of lacrimal sac were doughy in consistency. The conjunctival mass was excised and thermocautery applied. For the cases of lacrimal sac dacryocystectomy was done.Results: The cases were more common in male children of low socioeconomic status. Palpebral conjunctiva is the common site of involvement. History of pond bath was present in almost all the cases. History of bleeding from nose and eye was present in many cases.Conclusions: Rhinosporidiosis is a common condition of our locality. Treatment is simple by excising the growth and cauterising the site. Taking bath in pond water is supposed to be the cause of the disease. The disease can be prevented by avoiding pond bath.


Crisis ◽  
2011 ◽  
Vol 32 (1) ◽  
pp. 43-51 ◽  
Author(s):  
Eugene Kinyanda ◽  
Ruth Kizza ◽  
Jonathan Levin ◽  
Sheila Ndyanabangi ◽  
Catherine Abbo

Background: Suicidal behavior in adolescence is a public health concern and has serious consequences for adolescents and their families. There is, however, a paucity of data on this subject from sub-Saharan Africa, hence the need for this study. Aims: A cross-sectional multistage survey to investigate adolescent suicidality among other things was undertaken in rural northeastern Uganda. Methods: A structured protocol administered by trained psychiatric nurses collected information on sociodemographics, mental disorders (DSM-IV criteria), and psychological and psychosocial risk factors for children aged 3–19 years (N = 1492). For the purposes of this paper, an analysis of a subsample of adolescents (aged 10–19 years; n = 897) was undertaken. Results: Lifetime suicidality in this study was 6.1% (95% CI, 4.6%–7.9%). Conclusions: Factors significantly associated with suicidality included mental disorder, the ecological factor district of residence, factors suggestive of low socioeconomic status, and disadvantaged childhood experiences.


Crisis ◽  
2018 ◽  
Vol 39 (5) ◽  
pp. 397-405 ◽  
Author(s):  
Steven Vannoy ◽  
Mijung Park ◽  
Meredith R. Maroney ◽  
Jürgen Unützer ◽  
Ester Carolina Apesoa-Varano ◽  
...  

Abstract. Background: Suicide rates in older men are higher than in the general population, yet their utilization of mental health services is lower. Aims: This study aimed to describe: (a) what primary care providers (PCPs) can do to prevent late-life suicide, and (b) older men's attitudes toward discussing suicide with a PCP. Method: Thematic analysis of interviews focused on depression and suicide with 77 depressed, low-socioeconomic status, older men of Mexican origin, or US-born non-Hispanic whites recruited from primary care. Results: Several themes inhibiting suicide emerged: it is a problematic solution, due to religious prohibition, conflicts with self-image, the impact on others; and, lack of means/capacity. Three approaches to preventing suicide emerged: talking with them about depression, talking about the impact of their suicide on others, and encouraging them to be active. The vast majority, 98%, were open to such conversations. An unexpected theme spontaneously arose: "What prevents men from acting on suicidal thoughts?" Conclusion: Suicide is rarely discussed in primary care encounters in the context of depression treatment. Our study suggests that older men are likely to be open to discussing suicide with their PCP. We have identified several pragmatic approaches to assist clinicians in reducing older men's distress and preventing suicide.


Author(s):  
Ute Ritterfeld ◽  
Timo Lüke

Abstract. Audio stories offer a unique blend of narrative entertainment with language learning opportunities as a user’s enjoyment is dependent on their processing of the linguistic content. A total of 138 third- and fourth-graders from low socioeconomic status and migrant families recruited from a metropolitan area in Germany participated in a randomized pre–post follow-up intervention study with a control group. Children listened to a tailored crime story of approximately 90 min over a period of 3 days within the classroom setting. Entertainment value for the age group was established in a pilot study. Outcome variables included semantic and grammatical skills in German and were administered before (pretest), shortly after intervention (posttest), and 2 weeks later (follow-up). We used nonverbal intelligence, reading, comprehension skills, age and sex as control variables. Results indicate a strong positive effect of media reception on language skills. The effectiveness of the intervention is discussed with reference to different linguistic domains, entertainment value, and compensatory effects in populations at risk of language learning deficits.


2014 ◽  
Author(s):  
Sarah Dayle Herrmann ◽  
Jessica Bodford ◽  
Robert Adelman ◽  
Oliver Graudejus ◽  
Morris Okun ◽  
...  

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