scholarly journals PSYCHOEDUCATION, IMPROVING MEDICATION ADHERENCE AMONG INDIVIDUALS WITH BIPOLAR AFFECTIVE DISORDER

2020 ◽  
pp. 1-3
Author(s):  
Jai Shanker Patel ◽  
Manisha Kiran
Keyword(s):  
Medication Adherence ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Categorical Variables ◽  
Rank Test ◽  
Post Intervention ◽  
Chi Square ◽  
Chi Square Test ◽  
Wilcoxon Sign Rank ◽  
Sign Rank Test

AIM: aim of the present study to see the role of Psychoeducation in improvement of medication adherence among Bipolar Disorder. MATERIAL& METHODS: Present study was conducted in RINAPS, Ranchi and consisted of 24 samples, comprises into two groups 12 of ( TAU) and 12 of (TAU+PE) for 2 month of having 8 sessions. After 2 month post intervention and after 4 months follow up carried out to assess the result. RESULT AND CONCLUSION: The data analysis in the current study was done with help of non parametric test using SPSS version 20 for categorical variables chi square test, comparison between group Mann Witnney U test and for comparison within group Wilcoxon Sign Rank test was used. Post intervention nding indicates Psychoeducation is helpful in improving medication adherence among individuals with Bipolar Affective Disorder

scholarly journals PENGARUH PEMBERIAN BUAH NAGA TERHADAP KADAR HEMOGLOBIN PADA IBU HAMIL TRIMESTER III DI KLINIK BIDAN SRI WAHYUNI KECAMATAN UJUNG PADANG KABUPATEN SIMALUNGUN TAHUN 2020

2021 ◽  
Vol 3 (2) ◽  
pp. 188-201
Author(s):  
Desideria Yosepha Ginting ◽  
Layari Tarigan ◽  
Susi Endriyana
Keyword(s):  
Sample Selection ◽  
The Body ◽  
Rank Test ◽  
P Value ◽  
Post Intervention ◽  
Wilcoxon Sign Rank Test ◽  
Dragon Fruit ◽  
Quasi Experimental ◽  
Wilcoxon Sign Rank ◽  
Sign Rank Test

ABSTRACT Anaemia or often referred to as lack of blood is a condition in which the number of red blood cells decreases and results in insufficient oxygen-carrying capacity to meet the body's physiological needs. Problems that arise include an increase in heart rate due to the body trying to provide more oxygen to the tissues, an increase in respiratory rate as the body tries to provide more oxygen to the blood, dizziness due to lack of blood to the brain, feeling tired due to increased oxygenation of various organs including the heart muscle. and skeletal, pale skin due to reduced oxygenation, nausea due to decreased gastrointestinal blood flow and central nervous system, decreased hair and skin quality. Overcoming complaints of anaemia non-pharmacological can be done with dragon fruit. The purpose of this study was to determine the effectiveness of dragon fruit in dealing with complaints of anaemia in the Sri Wahyuni ​​clinic, Ujung Padang sub-district, Simalungun district in 2020. This study used a quantitative method, with a quasi-experimental design with a control time-series design. The population of this study were pregnant women who experienced symptoms of anaemia at the Sri Wahyuni ​​Clinic, Ujung Padang District, Simalungun Regency. The sample selection using purposive sampling of 14 people, 7 people were given intervention and 7 people as controls. The results of the study using the Wilcoxon sign rank test showed that the results for the group given pre and post-intervention p-value 0.026 <0.05. The results of the study using the Wilcoxon sign rank test showed that the control p-value was 0.000 <0.05. The conclusion is that there are differences in the two groups after being given dragon fruit in overcoming complaints of anaemia.

Seasonal influences on admissions for affective disorder and schizophrenia in Ireland: a comparison of first and readmissions

1999 ◽  
Vol 14 (5) ◽  
pp. 251-255 ◽  
Author(s):  
M. Clarke ◽  
P. Moran ◽  
F. Keogh ◽  
M. Morris ◽  
A. Kinsella ◽  
...  
Keyword(s):  
Seasonal Variation ◽  
Affective Disorder ◽  
Linear Model ◽  
Bipolar Affective Disorder ◽  
Psychiatric Inpatient ◽  
Seasonal Effects ◽  
Chi Square ◽  
Chi Square Test ◽  
Seasonal Influences ◽  
Log Linear

SummaryAlthough genetic and environmental factors operating before or around the time of birth have been demonstrated to be relevant to the aetiology of the major psychoses, a seasonal variation in the rates of admission of such patients has long been recognised. Few studies have compared first and readmissions. This study examined for seasonal variation of admission in the major psychoses, and compared diagnostic categories by admission status. Patients admitted to Irish psychiatric inpatient facilities between 1989 and 1994 with an ICD-9/10 diagnosis of schizophrenia or affective disorder were identified from the National Psychiatric Inpatient Reporting System (NPIRS). The data were analysed using a hierarchical log linear model, the chi-square test, a Kolmogorov-Smirnov (KS) type statistic, and the method of Walter and Elwood. The hierarchical log linear model demonstrated significant interactions between the month of admission and admission order (change in scaled deviance 28.77, df = 11, P < 0.003). Both first admissions with mania, and readmissions with bipolar affective disorder exhibited significant seasonality. In contrast, only first admissions with schizophrenia showed significant seasonal effects. Although first admissions with mania and readmissions with bipolar disorder both show seasonality, seasonal influences appear to be more relevant to onset of schizophrenia than subsequent relapse.

Impact of ABL kinase domain mutations on the outcome of patients with chronic myeloid leukemia (CML).

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 6588-6588
Author(s):  
Kendra Lynn Sweet ◽  
Rami S. Komrokji ◽  
Najla Al Ali ◽  
Robert M. Crescentini ◽  
Gelenis Domingo ◽  
...  
Keyword(s):  
Clonal Evolution ◽  
Kinase Domain ◽  
Categorical Variables ◽  
Rank Test ◽  
Cancer Center ◽  
Survival Times ◽  
Chi Square ◽  
Abl Kinase ◽  
Chi Square Test ◽  
Poor Outcomes

6588 Background: Patients with CML who develop resistance to imatinib commonly have mutations in the BCR-ABL kinase domain (KDM). Studies looking at outcomes in patients with P-loop versus non-P-loop mutations within the ABL-Kinase Domain have produced conflicting results. Methods: The Total Cancer Care (TCC) database was used to identify patients with CML treated at Moffitt Cancer Center (MCC). Descriptive data were reported, chi square test was used for categorical variables, and Kaplan Meier curves were used for OS and PFS. Log rank test was used to compare survival times between groups. Results: Between 1992 and 2011, 540 CML patients were treated at MCC. Of those, 51% were male and 71% were under the age of 60. Sixty percent (n=322) were diagnosed after 2001. Of the 540 patients, 6.5% (n=35) were found to have mutations of which 26 were detected in patients diagnosed after 2001. Of the 35 patients, 74% (n=26) had single mutations and 26% (n=9) had compound mutations. P-loop mutations were seen in 17% (n=6) and 43% (n=15) had T315I mutations. Patients with KDM progressed to accelerated or blast phase in 46% (n=16) of cases compared to 27% (n=136) without mutations (p=0.03). Median OS was 126 months, 109 months, and not reached in patients with P-loop, T315I, and non-P-loop mutations respectively (p=0.17). The corresponding median PFS was 85 months, 89 months, and not reached (p=0.20). In patients with one mutation median OS was not reached compared to 105 months in patients with compound mutations (p=0.27). After 2001, patients with KDM had a median PFS of 75 months and OS of 126 months while neither was reached in the non-mutation cohort (p=0.007, p=0.26 respectively). Median PFS in patients with single mutations was 85 months versus 10 months in those with compound mutations (p=0.037). Patients with KDM had additional Ph+ clones on cytogenetics in 49% of cases compared with 19% of cases in the non-mutation group (P < 0.005). Conclusions: T315I and P-loop KDM predict PFS and OS in CML patients, and convey a trend for worse prognosis. The presence of additional Ph+ clones in patients with BCR-ABL KDM indicates a higher level of genetic instability and clonal evolution, which may be the contributing factor to poor outcomes.

PENGARUH PSIKOEDUKASI TERHADAP PERILAKU ORANG TUA DALAM MERAWAT ANAK KRITIS DI PEDIATRIC INTENSIVE CARE UNIT RSUP Dr. SARDJITO YOGYAKARTA

1970 ◽  
Vol 4 (2) ◽  
Author(s):  
Ignasia Yunita Sari
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Rank Test ◽  
Wilcoxon Sign Rank Test ◽  
Post Test ◽  
Quasi Experimental ◽  
Wilcoxon Sign Rank ◽  
Sign Rank Test

Krisis situasi orang tua akibat kondisi anak yang dirawat di Pediatric Intensive Care Unit (PICU) menghambat peran serta orang tua dalam merawat anak. Psikoedukasi dapat menurunkan stress sehingga meningkatkan peran serta orang tua dalam mendukung perawatan anak. Tujuan penelitian ini adalah mengetahui pengaruh psikoedukasi terhadap perilaku orang tua dalam merawat anak kritis di PICU. Metode yang digunakan adalah quasi experimental dengan pre-test and post-test without control, pada bulan Maret-April 2015. Populasi adalah orang tua yang anaknya sedang dirawat di PICU RSUP Dr. Sardjito Yogyakarta. Teknik consecutive sampling menghasilkan 37 orang tua yang memenuhi kriteria. Variabel bebas adalah psikoedukasi, variabel terikatnya adalah perilaku orang tua dalam merawat anak kritis. Test dilakukan dengan cara observasi oleh observer yang telah dilakukan uji reliabilitas pengamatan menggunakan cohen cappa dengan hasil antara 0,60-0,73(baik). Analisis data menggunakan Wilcoxon Sign Rank Test dengan batas kemaknaan 95%. Psikoedukasi berpengaruh terhadap perilaku orang tua dalam merawat anak kritis di PICU. Kata kunci: psikoedukasi - perilaku orang tua - anak kritis

scholarly journals Short-Term Effect of Orthodontic Treatment with Clear Aligners on Pain and sEMG Activity of Masticatory Muscles

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 178
Author(s):  
Alessandro Nota ◽  
Silvia Caruso ◽  
Shideh Ehsani ◽  
Gianmaria Fabrizio Ferrazzano ◽  
Roberto Gatto ◽  
...  
Keyword(s):  
Surface Electromyography ◽  
Orthodontic Treatment ◽  
Masticatory Muscles ◽  
Rank Test ◽  
Nominal Data ◽  
Chi Square ◽  
Initial Reduction ◽  
Signed Rank Test ◽  
Chi Square Test ◽  
Semg Activity

Background and objectives: The aim of this study is to evaluate mandibular elevator muscles activity and pain on palpation in the early stages of orthodontic treatment with clear aligners using surface electromyography (sEMG). Materials and methods: Surface electromyography (sEMG) activity and pain level on muscle palpation of masseter and anterior temporalis muscles were recorded in a sample of 16 adult subjects (aged 18–32 years; mean 22.5 +/− 3.5 SD) undergoing orthodontic treatment with clear aligners before the treatment (T0), after 1 month of treatment (two clear aligners) (T1), and after 3 months of treatment (T2) (six clear aligners). A chi-square test for nominal data, a Friedman test, and a Wilcoxon-signed rank test as post hoc analysis were applied. Results: No statistically significant differences in muscular pain were observed. At T1, the sEMG activity of masseter muscles at mandibular rest position showed a statistically significant reduction, but after 3 months (T2), the data appeared similar to T0 (p = 0.03 and p = 0.02). Conclusions: During the treatment with clear aligners, subjects could experience an initial reduction in the masseter basal activity after 1 month of treatment. This effect tends to decrease to baseline levels after 3 months of therapy.

scholarly journals 350. Neurocysticercosis – Gender Differences in Clinical Presentations

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S244-S244
Author(s):  
Bharath Pendyala ◽  
Prasanth Lingamaneni ◽  
Patricia DeMarais ◽  
Lakshmi Warrior ◽  
Gregory Huhn
Keyword(s):  
Gender Differences ◽  
Categorical Variables ◽  
Public Health Issue ◽  
Diagnostic Code ◽  
Continuous Variables ◽  
Chi Square ◽  
Generalized Seizures ◽  
Icd 10 ◽  
Chi Square Test ◽  
Reported Data

Abstract Background Neurocysticercosis is a Neglected Tropical Disease and an important public health issue. Our goal was to collect and analyze data regarding clinically significant gender differences among our Neurocysticercosis patients. Methods A retrospective chart search with ICD 9/ ICD 10 diagnostic code for Neurocysticercosis and neuroimaging suggestive of Neurocysticercosis was performed for clinical encounters in the hospital or affiliated clinics between years 2013–2018. After a careful chart review, patients who were clinically diagnosed with Neurocysticercosis were included in the study. T-test was used to compare means of continuous variables and chi-square test to compare proportions of categorical variables. Results Among 90 total patients included, male (49.4%) and female (50.6%) distribution were nearly identical. The mean age in females was found to be higher than males (52.5 vs 42.0, P &lt; 0.0001). Almost an equal number of males and females presented with either seizures (63.6% vs 57.8%, P= 0.85), headaches (25.0% vs 28.9%, p= 0.85), or other symptoms (11.4% vs 13.3%, p= 0.85). Males had more generalized seizures compared to females (60% vs 38%, P= 0.37), although this result was not statistically significant. Females were more likely to present with &gt; 1 lesion (82.2% vs 56.8%, P= 0.01). Males were more likely to have cystic lesions (64.7% vs 27.9%, P &lt; 0.001) compared to females who had more calcified lesions on presentation (65.1% vs 20.6%, P &lt; 0.001). Male patients were more likely to have contrast enhancement or edema surrounding the lesions (61.4% vs 33.3%, P= 0.01) and were more likely to require treatment with Albendazole/Praziquantel (75.8% vs 31.7%, P &lt; 0.001). Conclusion Although previously reported data is limited, there is a suggestion that there are gender differences in host immune response and that inflammation surrounding parenchymal lesions is more intense in females. This study suggests that men either present early in the disease phase or have different immune responses than women and require anti-parasitic therapy more frequently. More research in this aspect is needed. Disclosures All Authors: No reported disclosures

Abstract 56: Acute Stroke Reperfusion Treatment Rates at NIH StrokeNET Hospitals

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Opeolu Adeoye ◽  
Dawn Kleindorfer
Keyword(s):  
Clinical Trials ◽  
High Volume ◽  
The United States ◽  
Primary Diagnosis ◽  
Categorical Variables ◽  
Phase 3 ◽  
Chi Square ◽  
Successful Recruitment ◽  
Chi Square Test ◽  
Reperfusion Phase

Background: In 2013, the NIH Stroke Trials Network (StrokeNET) was established to maximize efficiencies in stroke clinical trials. Successful recruitment in future trials was required for participating sites. A high volume of cases treated is a surrogate for the potential to recruit. Among Medicare-eligible acute ischemic stroke (AIS) cases, we estimated the IV rt-PA and endovascular embolectomy treatment rates at StrokeNET Regional Coordinating Centers and their partner hospitals compared with non-StrokeNET hospitals in the United States (US). Methods: We used demographics and IV rt-PA and embolectomy rates in the 2013 Medicare Provider and Analysis Review (MEDPAR) dataset. ICD-9 codes 433.xx, 434.xx and 436 identified AIS cases. ICD-9 code 99.10 defined rt-PA treatment and ICD-9 code 39.74 defined embolectomy. Demographics and treatment rates at StrokeNET and non-StrokeNET sites were compared using t-test for proportions and Chi-square test for categorical variables as appropriate. Results: Of 386,157 AIS primary diagnosis discharges, 5.1% received IV rt-PA and 0.8% had embolectomy (Table). By June 6, 2014, StrokeNET comprised 247 acute care hospitals that discharged 48,946 (13%) out of 386,157 AIS cases. rt-PA (7.4% vs 4.8%) and embolectomy (1.9% vs 0.6%) treatment rates were higher at StrokeNET hospitals. In 2013, 36% of StrokeNET hospitals treated more than 20 AIS cases with rt-PA or embolectomy compared with 6% of non-StrokeNET hospitals (P<0.0001).Conclusions StrokeNET hospitals treat more AIS cases with acute reperfusion therapies. Thus, StrokeNET could successfully recruit in acute reperfusion clinical trials depending on study size, capture of eligible patients and the number of competing trials. We likely underestimated treatment rates due to not accounting for drip-and-ship and non-Medicare cases. To further enhance enrollments in large acute reperfusion phase 3 trials, partnership with high volume non-StrokeNET hospitals may be warranted.

Change in perception of sclerotherapy results after exposure to pre–post intervention photographs

2017 ◽  
Vol 33 (4) ◽  
pp. 282-287 ◽  
Author(s):  
Fabricio R Santiago ◽  
Mario Piscoya ◽  
Yung-Wei Chi
Keyword(s):  
Varicose Veins ◽  
Statistical Significance ◽  
Wilcoxon Test ◽  
Clinical Severity ◽  
Post Intervention ◽  
Chi Square ◽  
Severity Scores ◽  
Venous Clinical Severity Score ◽  
Before And After ◽  
Chi Square Test

Objective To evaluate patients’ self-perception of cosmetic improvement before and after they were presented with pre- and postprocedure photographs after sclerotherapy with 75% dextrose. Methods Treatments included sclerotherapy of reticular and varicose veins using 75% dextrose. All treated limbs were photographed and classified according to Clinical, Etiology, Anatomy, and Pathology classification and Venous Clinical Severity Score pre- and posttreatment. The patients were queried before and after viewing the photos during these visits and indicated if they were very unsatisfied, dissatisfied, satisfied, or very satisfied. Nonparametric kappa correlation coefficient and a Chi square test were used to measure associations among agreement (p < 0.05 indicated statistical significance). The paired Wilcoxon test was used to compare statistical differences in mean Venous Clinical Severity Scores measured at different times (p < 0.05 indicated statistical significance). Data were analyzed using STATA software (version 12). Results Individuals were more satisfied with the results of sclerotherapy after exposure to images portraying their limbs two months after the procedure (p = 0.0028). This effect was maintained six months after sclerotherapy (p = 0.0027). Conclusion Patient exposure to pre- and postsurgical photographs is a simple intervention with the potential of improving patient satisfaction up to six months after treatment with sclerotherapy.

scholarly journals EFFECT OF MINDFULLNESS MEDITATION ON STRESS LEVEL AND COPING MECHANISM IN CANCER PATIENTS

2017 ◽  
Vol 53 (1) ◽  
pp. 33 ◽  
Author(s):  
Yesiana Dwi Wahyu Werdani
Keyword(s):  
Cancer Patients ◽  
Mindfulness Meditation ◽  
Brain Regions ◽  
Coping Mechanisms ◽  
Rank Test ◽  
Post Test ◽  
Wilcoxon Sign Rank ◽  
Sign Rank Test ◽  
And Coping ◽  
Physical Changes

Cancer patients have a tendency to experience mental disorders, because the physical changes cause frustration and despair. It impacts on anxiety, depression, and social isolation. The purpose of this study was to analyze the influence of mindfullness meditation to stress levels and coping mechanisms in cancer patients. This study used pre experimental approach with one group pre-test post-test design. Samples were 32 cancer patients with composmentis condition in Indonesian Cancer Foundation East Java Branch, taken by total sampling. The instrument was Perceived Stress Scale and Coping Strategies Inventory. Statistics was verified with Wilcoxon Sign Rank Test and Paired T-test P < 0.05. Results showed the effect of Mindfulness Meditation on the level of stress p = 0.001, the adaptive of coping mechanisms p = 0.001 and maldaptive p = 0.003. In conclusion, Mindfulness meditation can cause the respondent to concentrate and focus on themselves, and also strengthen brain regions at the center of attention and executive function, interoception and mental flexibility.

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