SURGICAL MANAGEMENT OF CORNEAL LIMBAL DERMOIDS BY SIMPLE EXCISION

2021 ◽  
pp. 1-2
Author(s):  
Birjees Hakak ◽  
Syed Tariq Qureshi ◽  
Haniyaa Mufti
Keyword(s):  
Age Groups ◽  
Goldenhar Syndrome ◽  
Female Ratio ◽  
Medical College ◽  
Simple Excision ◽  
Temporal Quadrant ◽  
Male To Female ◽  
Systemic Associations ◽  
Limbal Dermoid

Aim: To study clinical features and surgical outcomes of limbal dermoid excision in Kashmiri patients. Study Design :Interventional, Prospective Material and Methods: 20 patients with epibulbar limbal dermoid who attended the Out Patient department of Government Medical College ,Srinagar, from August 2019 to September 2020, across all age groups were included in the study. All the patients were examined for site, colour, presence of pigmentation and presence of ocular and systemic associations of the lesions and then surgically managed. Simple Excision was done with blade and scissors. Postoperative follow up was done upto 3 months Results: The age group included was 4 to 60 years with male to female ratio 3:2. All the patients had unilateral epibulbar dermoids located at infero-temporal quadrant of the limbus. Most lesions (13 cases - 65%) extended equally to cornea and sclera while a few extended more on the sclera (3 cases - 15%) or cornea (3 cases - 15%). Most (15 cases - 75%) were round. Two (10%) had Goldenhar Syndrome and both had preauricular tags and maxillary hypoplasia. Postoperatively one patient (5%) had corneal thinning and two(10%) patients had granulation tissue formation.Pigmentation of the lesion was seen in 18 cases (80%). Conclusion:Limbal dermoids in Kashmiri patients have clinical characteristics resembling those described in other parts of the world. Treatment with simple excision and supercial sclerokeratectomy gives satisfactory results.

scholarly journals A study on clinical characteristics of herpes zoster in a tertiary care center

2017 ◽  
Vol 3 (1) ◽  
pp. 79
Author(s):  
Rachana R. ◽  
Shivaswamy K. N. ◽  
Anuradha H. V.
Keyword(s):  
Herpes Zoster ◽  
Clinical Characteristics ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Age Group ◽  
Female Ratio ◽  
Varicella Zoster ◽  
Medical College ◽  
Male To Female

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Herpes zoster (HZ), also known as shingles, derived from the Latin word Cingulum, for “girdle”. This is because a common presentation of HZ involves a unilateral rash that can wrap around the waist or torso like a girdle. HZ results due to reactivation of an earlier latent infection with the varicella zoster virus (VZV) in dorsal root ganglia. It occurs at all age groups, common over 60 years of age. It is estimated that in non-immune populations, approximately 15 cases per 1000 people occur per year. The objective of the study was to study the clinical characteristics in patients with uncomplicated herpes zoster.</span></p><p class="abstract"><strong>Methods:</strong> A total of 72 patients attending dermatology OPD at Ramaiah medical college between June 2013 to September 2014 were recruited after obtaining informed consent. A detailed history regarding onset of rash, pain, progression, duration and distribution of the lesions were recorded. Demographic information including age, sex, and any other co morbidities noted. Tzanck smear and serology for HIV was done where-ever necessary.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Of the 72 patients, females outnumbered males [M=35(48.61%), F=37 (51.39%)] with male to female ratio of 0.9 to 1. The mean age of presentation was 58±18 years. Majority of the patients (54%) were in the age group of 51 to 70 years followed by 31-50 years (25%). Least number of cases (9%) was in the age group of 21 to 30 years. Of the 72 subjects, thoracic involvement was noted in 30.6%, followed by lumbar (22%), and trigeminal (16%). Cervical (4%) and sacral (2%) involvement was the least. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Herpes zoster commonly occurs in old age and the presenting symptom being pain and burning sensation. Thoracic dermatome is the commonest site. Immunocompromised states like diabetes, malignancy and HIV can increase the risk of developing herpes zoster.</span></p>

scholarly journals Follow-up of the air pollution and the human male-to-female ratio analysis in São Paulo, Brazil: a times series study

BMJ Open ◽  
2013 ◽  
Vol 3 (7) ◽  
pp. e002552 ◽  
Author(s):  
Simone Georges El Khouri Miraglia ◽  
Mariana Matera Veras ◽  
Luis Fernando Amato-Lourenço ◽  
Fernando Rodrigues-Silva ◽  
Paulo Hilário Nascimento Saldiva
Keyword(s):  
Air Pollution ◽  
Sao Paulo ◽  
Ratio Analysis ◽  
São Paulo ◽  
Female Ratio ◽  
Times Series ◽  
Human Male ◽  
Male To Female ◽  
Series Study

scholarly journals Clinicopathological study of sinonasal masses

1970 ◽  
Vol 16 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Abu HenaMohammad Parvez Humayun ◽  
AHM Zahurul Huq ◽  
SM Tarequddin Ahmed ◽  
Md Shah Kamal ◽  
Kyaw Khin U ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Malignant Lesion ◽  
Malignant Tumour ◽  
Neck Surgery ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Study Setting ◽  
Head Neck Surgery ◽  
Head Neck

Objective: To observe the incidence, clinical presentation and to perform comparative studyof different sinonasal masses. Study design: Prospective study. Setting: Department ofotolaryngology and Head-Neck Surgery & ENT OPD of Chittagong Medical College Hospital.Patients & methods: 50 patients are included in this study (39 male & 11 female) between theages of 3 years and 80 years who were treated between August 2006 to January 2007. Studybased on history, clinical, radiological, laboratory and histopathological examination. Results:Mean age for male was 35.12 years and for female was 22.63 years. Male to female ratio was3.5:1. Highest frequency was noted in second decade. Most of patient (78%) were from poorclass. Frequency of inflammatory nasal masses were more in second decade, benign tumourin fourth and fifth decade, malignant tumour in second decade (OAN & NHL) and fifth andsecond decades (others). Rhinosporidiosis were most frequent inflammatory nasal masses.Nasal obstruction was the commonest and orbitus symptoms were less frequent symptoms.But orbital symptoms were more prevalent in malignant lesion. Conclusion: sinonasal massesare found in all age group. Rhinosporidiosis are appearing to be the commonest nasal masses.The prevalence of nasal polyp is also high. Among the malignant sinonasal masses thepercentage of squamous cell carcinoma is high.DOI: 10.3329/bjo.v16i1.5776Bangladesh J Otorhinolaryngol 2010; 16(1): 15-22

scholarly journals Ascitic Fluid Cytology Seen in a Tertiary Hospital in Nigeria

2020 ◽  
pp. 345-350
Author(s):  
CC Nwafor ◽  
K Obioha ◽  
TO Akhiwu
Keyword(s):  
Sex Ratio ◽  
Patient Care ◽  
Ascitic Fluid ◽  
Age Groups ◽  
Tertiary Hospital ◽  
Age Group ◽  
Malignant Cells ◽  
Female Ratio ◽  
Male To Female ◽  
Fluid Cytology

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria

scholarly journals Dengue Fever : Study of 100 Cases in a Tertiary Care Hospital in Dhaka City

2015 ◽  
Vol 24 (Number 1) ◽  
pp. 3-7
Author(s):  
A H M Karnal ◽  
K H Mollah ◽  
A Begum ◽  
K Khoda ◽  
S Tanzeem ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Tertiary Care ◽  
Hemorrhagic Fever ◽  
Viral Disease ◽  
Care Hospital ◽  
College Hospital ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Body Ache

Dengue is a rapidly spreading mosquito-borne viral disease worldwide. The endemicity in Bangladesh is also increasing gradually. The study was a prospective observational one, documented the presenting features and outcome of management. It was carried out in Department of Medicine in Holy Family Red Crescent Medical College Hospital, Dhaka from June 2013 to December 2013. Total 100 admitted cases of both sera positive and sera-negative were included in this study. Detailed history was taken, clinical examination and relevant investigations were done. Out of 100 patients 54 (54%) were male and 46 (46%) were female. So male to female ratio was 1.7:1. The age of the patients ranged from 12-75 years. Among them 20-40 years age group was highest 63%. Patients of higher socio-economic group were (69%) more affected. Out of 100 cases 54 had classical dengue fever (DF), 46 had dengue hemorrhagic fever (DHF). Antibody was positive in 81% cases. All patients presented with high fever, headache in 90%, retro-orbital pain in 45%, body ache in 56%, and backache in 48%. Leucopenia found in 60, platelet count <100x1091L was in 57, HCT- normal 17, <20% rise in 48%, ?20% rise in 28%. With proper management all patients were recovered.

scholarly journals Effectiveness of Liraglutide in Type II Diabetes Mellitus Management: Experience in Emirati Patients

2015 ◽  
Vol 8 ◽  
pp. CMED.S31756 ◽  
Author(s):  
Nasrullah K. Ghuman ◽  
Loai M. Saadah ◽  
Majdi S. Al Najjar ◽  
Duha Y. Shaheen ◽  
Shady I. AM ◽  
...  
Keyword(s):  
Standard Form ◽  
Type Ii Diabetes Mellitus ◽  
Military Hospital ◽  
Patient Visit ◽  
Female Ratio ◽  
P Values ◽  
Patients Âgés ◽  
Male To Female ◽  
Univariate Analyses

Objective To measure effectiveness of liraglutide in reducing glycated hemoglobin (HbA1C), weight, and systolic blood pressure (SBP) in Emirati patients. Design A retrospective cohort study. Setting Endocrinology clinic in a 300-bed military hospital. Patients A total of 152 patients who qualified for liraglutide between September 21, 2012, (first patient visit) and May 5, 2014 (last patient visit). Methods Team collected demographic and clinical data using a standard form. Data keeper performed univariate analyses to measure the effect of liraglutide in reducing the three outcomes of interest; namely, HbA1C, weight, and SBP. Results One hundred patients had at least the first visit in the clinic and 98 patients came for a second follow-up visit while on the medication. Adherence of clinicians to the internal criteria for prescribing liraglutide was 92%. Patients' ages were 47.9 ± 11.7 years. Male-to-female ratio was almost 1:1. Overall, in the paired analyses, HbA1C decreased from first to second visits (8.7 ± 1.9 vs. 7.6 ± 1.8, P < 0.0001) and remained unchanged in subsequent visits (eg, in visit 3, HbA1C was 7.4 ± 1.8). Patients lost an average of 1.3 kg between the first and second visits (99.3 ± 19.3 vs. 98.0 ± 19.5, P = 0.0003). The reduction in SBP between visits 1 and 2 was less (130.9 ± 15.8 vs. 129.9 ± 16.5, P = 0.5896). ANOVA yielded a significant reduction in HbA1C at 4 months and 6 months ( P values < 0.05). SBP dropped by about 3.6 mmHg and weight by about 2.3 kg ( P values > 0.05). Conclusions Liraglutide is effective in reducing HbA1C, weight, and to a lesser extent, SBP in Emirati patients.

scholarly journals Correlation between Clinical Symptoms of Various Colorectal Diseases and Colonoscopic Findings

2019 ◽  
Vol 17 (1) ◽  
pp. 16-19
Author(s):  
Roman Kidwai ◽  
Anup Sharma
Keyword(s):  
Diagnostic Accuracy ◽  
Clinical Symptoms ◽  
Colorectal Polyps ◽  
Bowel Habit ◽  
Female Ratio ◽  
Medical College ◽  
Inflammatory Conditions ◽  
The Mean ◽  
Colorectal Diseases ◽  
Male To Female

Background: About 30% of patients presenting to surgical outpatient department has lower gastrointestinal (LGI) symptoms. Colonoscopy is a low risk and at the same time investigation of choice in these patients which allows visualization of the entire colon and the terminal portion of ileum. This study was done to find out the diagnostic accuracy of colonoscopy in relation to the clinical symptoms of the disease.  Methods: This was a prospective, hospital based study from February 2014 to March 2019 carried out at Nepalgunj Medical College and Teaching Hospital. The colonoscopy diagnosis was compared with the clinical symptoms and further confirmed with histological examination.  Results: 341 patients underwent colonoscopy. There were 234 (68.62%) males and 107 (31.37%) females with the male to female ratio of 2.18: 1. The age ranged from 16 to 81 with the mean age of 59.63±10.37. The most common presenting symptom was per rectal bleeding (40.34%) the after were alteration in bowel habit (17.30%), constipation (12.90%), hematochezia (11.43%). The least common indication for colonoscopy was unexplained anemia. Haemorrhoids were the most common findings consisting 32.55%. In 19.94% it was normal. Majority had various inflammatory conditions, among them 10.85% had proctocolitis, 2.34% were suspected to have ulcerative colitis. There were 17(4.98%) patients with colonic and 13(3.18%)with rectal carcinoma. 10.55% had colorectal polyps. Out of 111 patients suspected to have hemorrhoids clinically 102 had same findings on colonoscopy. Similarly 34 patients presenting with chronic diarrhea with bleeding and 59 with alteration in bowel habit where inflammatory conditions were suspected had similar findings on colonoscopy in 29 and 34 patients respectively. Similarly the suspicion of malignancy on clinical basis was also correlated on colonoscopy. The inflammatory conditions diagnosed on colonoscopy were confirmed in 85.04 % by histology. Similarly malignancy and the presence of polyps diagnosed on colonoscopy were confirmed by histology in 97.05% and in 97.22% cases respectively. Conclusion: Colonoscopy is a safe and effective investigation to diagnose various colorectal conditions. There was a correlation between the clinical symptoms and the colonoscopicdiagnosis especially in conditions like inflammatory and neoplastic colorectal diseases. When combined with histology the diagnostic accuracy can be near 100% in conditions like inflammatory and benign or malignant diseases.

scholarly journals Aetiological factors of hoarseness in patients attending at Kathmandu University Hospital

2013 ◽  
Vol 19 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Bikash Lal Shrestha ◽  
Ram Chaya Man Amatya ◽  
Sekhar KC ◽  
Inku Shrestha ◽  
Monika Pokharel
Keyword(s):  
Longitudinal Study ◽  
Age Groups ◽  
University Hospital ◽  
Microsoft Excel ◽  
Special Investigation ◽  
Female Ratio ◽  
Common Cause ◽  
Manual Analysis ◽  
History Of ◽  
Male To Female

Objective: To evaluate the aetiological factors of hoarseness. Methods: This is a prospective, non- randomized and longitudinal study conducted from 1st august 2011 to 1st august 2012 in department of otorhinolaryngology of Kathmandu university Hospital, Dhulikhel, Nepal. All the patients with history of hoarseness underwent clinical examination, routine as well as special investigation to find the diagnosis. The final results were analyzed by simple manual analysis with frequency and percentage using Microsoft Excel software 2007. Results: There were total 280 patients included in the study. Among them the age groups of 21 – 30 years and 31 – 40 years were mainly suffer from hoarseness. Similarly, among 280 patients 200 (71.45%) were males whereas 80 (28.6%) were females with male to female ratio of 2.5:1.. The most common cause as per the distribution was acid peptic laryngitis with frequency of 37.8% whereas tuberculosis of larynx, papillary carcinoma of thyroid and papilloma of vocal cord accounts for only 0.4% each. Conclusion: There was etiological variation in hoarseness ranging from simple laryngitis to malignancies. So it is important not to ignore the hoarseness and precise history, examination and investigations should be done. DOI: http://dx.doi.org/10.3329/bjo.v19i1.11877 Bangladesh J Otorhinolaryngol 2013; 19(1): 14-17

Primary non-Hodgkin's lymphoma of the nose and nasopharynx: clinical features, tumor immunophenotype, and treatment outcome in 113 patients.

1998 ◽  
Vol 16 (1) ◽  
pp. 70-77 ◽  
Author(s):  
M M Cheung ◽  
J K Chan ◽  
W H Lau ◽  
W Foo ◽  
P T Chan ◽  
...  
Keyword(s):  
Clinical Features ◽  
Survival Rates ◽  
Chinese Patients ◽  
Female Ratio ◽  
Cd56 Expression ◽  
T Lymphomas ◽  
Hodgkin's Lymphomas ◽  
Male To Female ◽  
Disease Free

PURPOSE To study the clinical features and outcome for primary non-Hodgkin's lymphomas of the nose/nasopharynx (NNP-NHLs) according to immunophenotype. PATIENTS AND METHODS One hundred thirteen Chinese patients with primary NNP-NHLs that belonged to the categories E, F, G, or H according to the Working Formulation (WF), with full immunophenotypic data and complete clinical follow-up data, were analyzed in this retrospective study. RESULTS Ninety (79.6%) patients had localized (stage I or II) disease, while 23 (20.4%) had stage III or IV disease. The lymphomas in 51 (45.1%), 24 (21.3%), and 38 (33.6%) patients showed natural killer (NK)/T- (CD56-positive), T-cell, and B-cell immunophenotype, respectively. Seventy-three patients (65.8%) achieved a complete remission, of whom 34 (46.6%) subsequently relapsed. The median follow-up time for those alive was 88 months. The 5-year actuarial disease-free and overall survival rates were 34.4% and 37.9%, respectively. Multivariate analysis showed that only stage and immunophenotype were significant for survival. NK/T lymphomas were distinctive among the three immunophenotypes in the following aspects: the highest male-to-female ratio, more frequent involvement of the nasal cavity alone, higher risk of dissemination to the skin, more frequent development of hemophagocytic syndrome, and the worst prognosis (overall median survival, 12.5 months). CONCLUSION The three immunophenotypes studied are shown to exhibit different clinical patterns. Since the NK/T phenotype carries the worst prognosis, patients who present with NNP-NHL should have their tumors analyzed for CD56 expression.

The Histopathologic Patterns of Intracranial Neoplasms in the Lagos University Teaching Hospital (LUTH), Idi-Araba, Lagos, Nigeria: A 10-Year Retrospective Study, January 2008 to December 2017

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S120-S121
Author(s):  
Kasiemobi Uchime ◽  
Luqman Adebayo ◽  
Charles Anunobi
Keyword(s):  
Teaching Hospital ◽  
Pituitary Adenomas ◽  
Age Groups ◽  
University Teaching ◽  
Geographical Differences ◽  
Intracranial Neoplasms ◽  
Female Ratio ◽  
Intracranial Neoplasm ◽  
Male To Female ◽  
Age And Sex

Abstract Objectives Intracranial neoplasms have distinct diagnostic histologic features and some are common in certain gender and age groups. The most common intracranial neoplasm worldwide is meningioma, followed by gliomas, most especially astrocytic tumors, and then pituitary adenomas. There are geographical differences in the pattern of occurrence of intracranial neoplasms. Few studies have been done in Nigeria to demonstrate the pattern of occurrence, age, and sex distributions of these neoplasms. The aim for this study is to establish the pattern of occurrence with age and sex distribution of different histologic types of intracranial neoplasm in our environment. This study may help portray the health burden of these tumors and aid in epidemiological studies. Methods A total of 296 patients (165 females, 131 males) diagnosed with intracranial neoplasms between January 2008 and December 2017 at Lagos University Teaching Hospital (LUTH), Idi-Araba, Lagos, Nigeria, were retrospectively analyzed. Patients’ data were retrieved from the archives of the Department of Anatomic and Molecular Pathology, LUTH, Idi-Araba, Lagos. Histologic patterns with age and gender distribution were noted. The data obtained were analyzed with SPSS version 23. Results Majority of the patients diagnosed with intracranial neoplasm were between 41 and 50 years of age. The most frequently diagnosed intracranial neoplasm at LUTH within the study period was meningioma (105 cases, median age of 42 years, male to female ratio of 3:7), followed by pituitary adenoma (78 cases, median age of 47 years, male to female ratio of 3:2), and then gliomas (66 case), most especially the astrocytic and oligodendroglial tumors (median age of 37 years, male to female ratio of 2:3). Conclusion The result of the study shows that the pattern of occurrence of primary intracranial neoplasms in our environment is different from that in Caucasians, with meningiomas being the most common, followed by pituitary adenomas and then gliomas.

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