scholarly journals Analysis of changes in the state of vaginal microflora in women of reproductive age under conditions of a three-day "dry" immersion without the use of prophylaxis

2022 ◽  
Vol 98 (6) ◽  
pp. 657-663
Author(s):  
V. K. Ilyin ◽  
V. V. Boyarintsev ◽  
D. V. Komissarova ◽  
K. A. Toniyan ◽  
N. A. Usanova ◽  
...  

Introduction. Currently, the participation of women in space flights is increasing. In this regard, questions about the influence of space factors on the state of the female body arise inevitably. Model experiments, in particular, "dry" immersion, are most convenient for studying the influence of individual factors of space flight on the organism. The aim of this work is a comparative assessment of the state of the vaginal microbiota of 6 female volunteers before and after three-day "dry" immersion.Materials and methods. Microbial samples of all volunteers were stained according to Gram with a sequential culture study in accordance with the medical technology. The species identification of microorganisms was performed by MALDI-TOF-MS analysis using an Autoflex III time-of-flight mass spectrometer with Maldi BioTyper software.To assess changes in the state of the vaginal microflora and microflora of the cervical canal, eubiotic index was used. It reflects the number of positive states of microbiota to the number of negative ones.Results. After 3 days of "dry" immersion volunteers, who had high titer of aerobic microorganisms before isolation, had significant increase of the amount of aerobic microorganisms, while the number of lactobacilli decreased. The other group of volunteers showed activation of colonization resistance of the vaginal microflora. Volunteers, who had a significant contamination with anaerobic opportunistic microflora before isolation, had reduction of the number of all anaerobes, including lactobacilli. The eubiotic index, calculated for the cervical canal, decreased after 3 days of immersion. The data obtained indicate that after 3 days of isolation, the state of the microflora has deteriorated.

Author(s):  
Наталья Резниченко ◽  
Галина Резниченко ◽  
Анатолий Дюдюн

Insufficient effectiveness of antibacterial and anti­inflammatory therapy dictates the need to find new ways of prevention and treatment of chronic recurrent inflammatory diseases of the vagina and cervix in women with the use of new generation multiprobiotics. Objective of the study: evaluation of the effectiveness of the use of a multipropiotic drug with propolis in the treatment of recurrent bacterial vaginitis in women of reproductive age - residents of a large industrial city. Materials and methods of the study: 69 patients aged 18 - 45 years with bacterial vaginitis living in the large industrial city of Zaporizhzhya were observed. The main group consisted of 14 women with inflammatory diseases of the vagina and cervix, who received in the complex treatment of multiprobiotics with propolis 1 dose 1 time a day in the vagina for 5 days. To determine the presence of an infec­tious agent, microscopic and bacteriological examination of vaginal and cervical canal secretions was performed, the species composition of pathogens was determined by PCR. Results of the study and their discussion. In patients with chronic vaginitis of reproductive age living in the conditions of a large industrial city there are pro­found disorders of the relationship between obligate and pathogenic microorganisms, which contributes to the re­currence of the pathological process. Conclusions. The use of a multiprobiotic drug with propolis, which has a broad antiviral and antibacterial properties, containing bifido, lacto, propionic acid bacteria and propolis can ef­fectively normalize the vaginal microflora in chronic vagi­nitis, shorten the development time and treatment. The results of the study give us grounds to recommend the widespread use of a propolis-based multipropiotic drug for women suffering from chronic vaginitis who are not amenable to standard anti-inflammatory therapy.


2003 ◽  
Vol 123 (0) ◽  
pp. 51-55
Author(s):  
Munenori Hayakawa ◽  
Tadao Nishimura ◽  
Kenji Suzuki ◽  
Natsuki Morishima ◽  
Nobuhiro Shibata ◽  
...  

Author(s):  
Sonalika Hiremath ◽  
Santhosh Kumar S. ◽  
Sridevi Swamy

Infertility primarily refers to the biological inability of a person to contribute to conception. In women, it may also refer to the state when she is not able to carry a pregnancy to its full term. Female infertility is caused due to structural problems like blocked Fallopian tubes, defect in cervical canal, uterine fibroid or polyps. Hormonal imbalance leading .ovulation problems too can cause infertility. From Ayurvedic perspectives, Shukra Dhatu can get affected by various physical, mental causes and even by serious diseases. Poor quality Shukra Dhatu can cause infertility in males and females.


2021 ◽  
pp. 056943452110105
Author(s):  
Marshall H. Medoff

This study, using state data, empirically examines the factors affecting the availability of abortion providers over the period 1992–2011. The empirical results found that the labor force participation of women and the percentage of women of reproductive age in the 18–24 age group were positively associated with the number of abortion providers in a state. The level of antiabortion activities and antiabortion attitudes were negatively associated with the number of abortion providers in a state. Also, a state’s abortion rate was positively associated with the number of abortion providers. The enforcement of a parental involvement law by a state significantly deters physicians or organizations from becoming or remaining abortion providers. JEL Classifications: I11, I18, K32, K38


2021 ◽  
pp. 001458582110225
Author(s):  
Thomas E Peterson

A central question facing the reader of the Paradiso terrestre (Pg 28–33) concerns the selfhood of the protagonist, the character Dante. While the state of Dante’s soul was critical to the poem’s beginning in the dark wood, and remained implicit through the intervening cantos, it is only in the Paradiso terrestre that it becomes the poem’s central focus. This question is explored in cognitive and theological terms in a sequential reading of the six cantos that elucidates the learning process occurring in the character before and after his confession in Pg 31: in his encounter with Matelda, his sensory and perceptual experience of the procession, his dialogues with Beatrice, and his witnessing of her divine beauty as the analogia entis reflecting the beauty of God. The analysis acknowledges the changes in Dante’s style in this interval, which serves as a fulcrum of the entire Commedia, a spatio-temporal threshold in which the transition of one soul, from confession to redemption to instruction on the divine word, is linked to the destiny of humankind and the prospect of universal salvation. Throughout this process of becoming, the character’s cognitive limitations are exposed, not simply as flaws but as signs of his intrinsic humanity.


2020 ◽  
Vol 30 (11) ◽  
pp. 4505-4509
Author(s):  
Anna Różańska-Walędziak ◽  
Paweł Bartnik ◽  
Joanna Kacperczyk-Bartnik ◽  
Krzysztof Czajkowski ◽  
Maciej Walędziak

Abstract Introduction Obesity is associated with hyperestrogenism along with other hormonal abnormalities affecting the menstrual cycle. The most effective and decisive method of obesity treatment is bariatric surgery. The aim of this study was to analyze the impact of bariatric surgery on menstrual cycle, the incidence of menstrual abnormalities, hyperandrogenism manifestation, and contraception use. Materials and Methods It was a cross-sectional study of 515 pre-menopausal women who had undergone bariatric surgery between 1999 and 2017 in a bariatric center. Data was collected via anonymous questionnaire, and the questions covered a 1-year period before the surgery and the last year before questionnaire completion. Results Before the surgery, 38.6% of the patients reported irregular menstruations in comparison with 25.0% after bariatric surgery (RR = 0.65; 95%CI 0.53–0.79). The mean number of menstruations per year did not differ before and after surgery (10.2 ± 3.9 vs 10.4 ± 3.3; p < .45). There were no statistically significant differences in terms of prolonged menstruations, acne, and hirsutism prevalence. A total of 14.4% of patients before surgery reported estrogen-based contraception use in comparison with 15.0% after the surgery (p < .95). There were no significant differences in the frequency of OC use (11.0% before surgery vs 13.6% 12 months after the surgery vs 11.5% at the moment of survey administration; p < 0.46). Conclusion Bariatric surgery improves the regularity of the menstrual cycle in obese women in reproductive age. The lack of any changes in the combined hormonal contraception (CHC) use, especially OC, before and after bariatric surgery may be a result of a possibly low level of contraception counseling.


Author(s):  
Alois Paulin

In this study the authors analyze the effects of e-government reforms that began in mid-90ies by confronting the promises which these reforms made to government performance in the period before and after the reforms took place. The authors use fiscal and performance indicators of the Slovenian government and courts to argue that e-government did not yield any notable effects on the state performance. Finally, the authors analyze the reasons why e-government technology cannot be regarded as sustainable and suggest a different approach towards researching how to sustainably improve governance for generations to come.


2013 ◽  
Vol 4 (1) ◽  
pp. 57-82 ◽  
Author(s):  
Süleyman Polat

At the end of the sixteenth and the beginning of the seventeenth centuries the Celali revolts resulted in wide-scale destruction throughout the entire Anatolian region. While research has been done on the general effects of this destruction, in-depth work investigating the economic consequences of the Celali revolts based on extant economic data has yet to be undertaken. Using archival material it is, however, possible to show the economic effects of these revolts. Taking the fall in tax collected by the state from the population as a result of the Celali revolts, this article aims to show how these revolts affected the economic structure of the state. By comparing the levels of avarız taxes collected before and after the revolts, and by trying to establish the levels of tax set according to the tax unit, the avarız hanes, the article thus sets out the economic impact the revolts had in Anatolia.


2020 ◽  
pp. 58-66
Author(s):  
Ya. I. Uraeva ◽  
I. I. Ivanova ◽  
N. N. Lazarenko ◽  
E. V. Filatova ◽  
I. A. Pankova ◽  
...  

The results of the treatment of women (n = 94) suffering from genital endometriosis are presented. The first (control, n = 30) group of women received standard drug therapy; the second (main, n = 64) group of women additionally had hirudotherapy procedures using medical leeches. The course of treatment consisted of 10–12 procedures. The state of cerebral circulation was assessed according to the rheoencephalography data before and after the treatment, as well as after 1, 3, 6, and 9 months. As a result, in patients in the 2-nd (main) group receiving complex treatment, the state of cerebral circulation improved signifi cantly. Moreover, according to the statistical regression analysis, it was possible to predict its further decrease by two periods ahead, compared with the treatment results in patients in the 1-st (control) group.


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