scholarly journals The seroprevalence of SARS-CoV-2 among residents of the Khabarovsk Krai during the COVID-19 epidemic

2021 ◽  
Vol 98 (1) ◽  
pp. 7-17
Author(s):  
A. Yu. Popova ◽  
E. B. Ezhlova ◽  
A. A. Melnikova ◽  
O. E. Trotsenko ◽  
T. A. Zaitseva ◽  
...  
Keyword(s):  
Large Scale ◽  
Herd Immunity ◽  
Age Groups ◽  
Maximum Level ◽  
Fold Increase ◽  
Incidence Rates ◽  
High Rate ◽  
Slow Increase ◽  
Khabarovsk Krai ◽  
Epidemic Process

Introduction. The coronavirus disease (COVID-19) pandemic was announced by WHO in February 2020. In the Khabarovsk Krai, the first three cases of the disease were diagnosed on March 19, 2020, these cases were imported from Argentina (transit through Italy). The epidemic process of COVID-19 in the Khabarovsk Krai is characterized by a slow increase in the incidence. During the period of time when the SARS-CoV-2 seroprevalence study was conducted the incidence rates varied from 35.9 to 39.1 per 100 thousand population. Within the next 5 weeks the incidence continued to increase, the maximum level was 67.3 per 100 thousand population. A statistically significant decrease in the incidence is noted in the first decade of August. The study of the SARS-CoV-2 seroprevalence among residents of the region was carried out from June 9 to June 21, 2020 during the period of increasing intensity of the epidemic process of COVID-19 infection.Aim. To determine the level and structure of herd immunity to SARS-CoV-2 virus among the population of the Khabarovsk Krai during the period of intensive spread of COVID-19.Materials and methods. The study was conducted as a part of the first stage of a large-scale Rospotrebnadzor project to assess the herd immunity to SARS-CoV-2 virus among the population of the Russian Federation, taking into consideration the protocol recommended by WHO. The selection of volunteers for the study was carried out by the method of questionnaires and randomization by random sampling. The results of a survey of 2675 individuals were included into analysis. The number of volunteers in all age groups was similar.Results. The results of the study showed that the herd immunity to SARS-CoV-2 in the total population of the Khabarovsk Krai was 19.6%. The maximum level of herd immunity was observed in children 14–17 years old (34.4%), children 7–13 years old (24.8%), and people over 70 years (22.6%). The highest level of seropositivity, except for the children and the elderly, was found among educational workers (26.7%). The lowest level of seropositivity was found in the military (8.7%) and the unemployed (8.3%). There were no statistically significant differences in the level of seroprevalence between men and women.Conclusions. The results of the seroepidemiological study demonstrated that in the Khabarovsk Krai, the presence of the contacts with COVID-19 patients is associated with the 1.4-fold increase in the likelihood of the seroconversion. Antibodies were detected in 58.9% of the past COVID-19 cases. In individuals with the previous positive PCR test result, antibodies were detected in 50% of cases. A high rate of asymptomatic infection, up to 93.7%, was observed among seropositive volunteers.

scholarly journals Characteristic of herd immunity among the population of Stavropol region amid the COVID-19 epidemic

2021 ◽  
Vol 13 (4) ◽  
pp. 79-89
Author(s):  
A. Yu. Popova ◽  
E. B. Ezhlova ◽  
A. A. Melnikova ◽  
V. S. Smirnov ◽  
L. V. Lyalina ◽  
...  
Keyword(s):  
Herd Immunity ◽  
Age Groups ◽  
Population Level ◽  
Fold Increase ◽  
Disease Spread ◽  
Steady Increase ◽  
Epidemic Process ◽  
Population Immunity ◽  
First Case ◽  
Asymptomatic Volunteers

Introduction. The first pandemic in the 21st century, caused by the pathogenic representative of the coronavirus SARS-CoV-2, began in the Chinese city of Wuhan, where the first outbreak of coronavirus pneumonia was recorded in December 2019. The disease spread so quickly around the world that already on February 11, 2020, WHO was forced to declare a pandemic of the “coronavirus disease 2019” COVID-19. The first case of COVID-19 in the Stavropol Territory was registered on March 20, 2020, and three weeks later, starting from the 15th week of the year, a steady increase in the incidence began, which lasted until the 52nd week. During the study period, the incidence increased from 21.1 to 28.3 per hundred thousand of the population. Growth 1.3 times.Purpose: to determine the dynamics of population immunity among the population of the Stavropol Territory in 2020-2021. during the period of an epidemic increase in the incidence of COVID-19. Materials and methods. The SARS-CoV-2 study was carried out according to a unified methodology within the framework of the program for assessing the population immunity of the population of the Russian Federation, developed by Rospotrebnadzor with the participation of the St. Pasteur. In total, 2688 people were examined, divided into 7 age groups. In the examined individuals, the level of specific IgG to the SARS-CoV-2 nucleocapsid was determined by the enzyme immunoassay.Results. The level of seroprevalence among residents of the Stavropol Territory was 9.8%. The largest proportion of seropositive individuals was found in the age groups 1-6 and 7-13 years old (19.2% and 19.7%, respectively). Seroprevalence had no gender differences and ranged from 9.3% to 10.8%. When assessing the distribution of the proportion of seropositive persons in different geographic territories of the region, it was found that the maximum proportion was found in the Kochubeevsky district (23.1%), the minimum in Kislovodsk (7.7%). Among convalescents, the content of specific antibodies to SARS-CoV-2 was noted in 73.3%, which is 7.8 times higher than the average population level. When conducting seromonitoring in the 2nd half of 2020, a 10-fold increase in seroprevalence was recorded, accompanied by a decrease in incidence from the 5th week of 2021. Among asymptomatic volunteers in whom SARS-CoV-2 RNA was detected by the polymerase chain reaction, antibody titers to viruses were found in 78.6%, which corresponds to the seroprevalence of convalescents. The proportion of seropositive persons among those who have come into contact with COVID-19 patients was 16.4%, (1.8 times higher than the average for the population). Out of 262 seroprevalent volunteers, the asymptomatic form of SARS-CoV-2 was detected in 92% of the examined, which indicates a significant role of the number of asymptomatic forms of infection in the epidemic process of COVID-19.Conclusion. The results of assessing the population immunity of the population of the Stavropol Territory indicate that it has not yet reached the threshold level at which a decrease in the intensity of the COVID-19 epidemic process can be expected. 

Features of the Current Epidemic Process of Infectious Mononucleosis in the Nizhny Novgorod Region

2021 ◽  
pp. 79-86
Author(s):  
MI Popkova ◽  
OV Utkin
Keyword(s):  
Infectious Mononucleosis ◽  
Average Rate ◽  
Disease Incidence ◽  
Age Groups ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Epidemic Process ◽  
Tract Infections ◽  
Nizhny Novgorod Region

Introduction: Today, we are witnessing the process of forming a fundamentally new epidemiological situation on infectious mononucleosis. Over the past decade, a general increase in the incidence of infectious mononucleosis, its proportion in the structure of respiratory tract infections, and economic importance was noted in Russia. Information about the epidemic process of infectious mononucleosis in different areas is limited. Our objective was to study the features of the epidemic process of infectious mononucleosis in the Nizhny Novgorod Region in 2010–2019. Methods: We conducted a retrospective epidemiological analysis of the incidence of infectious mononucleosis in the Nizhny Novgorod Region for 2010–2019 based on official statistics using standard statistical approaches. Results and discussion: The long-term incidence rate of infectious mononucleosis in the Nizhny Novgorod Region was stable (+0.6 %) with the long-term average rate of 12.6 ± 0.6 ‰оо. An autumn-winter-spring seasonality with two distinct peaks (in November–December and May) was revealed. The majority of cases were children aged 0–14 years (72.8 ± 2.2 %). The highest incidence rates were regis�tered in the age groups of 1–2 and 3-6 years. We established a reverse trend in the disease incidence among children aged 0–6 (decrease) and 7 years and older (increase). Adolescents aged 15–17 demonstrated the most pronounced growth rate (+7.5 %). The typical annual dynamics in adults was distinguished by a clear spring-summer seasonality, the absence of a characteristic growth in the autumn months, and a low rate in December. The identified features of the epidemic process in different age groups require clarification and detailing. Conclusions: We established recent patterns and features of the epidemic process of infectious mononucleosis in the Nizhny Novgorod Region. This work is an important component of epidemiological surveillance of infection and a scientific basis for improving the existing system of preventive and anti-epidemic measures.

ANNUAL DYNAMICS OF PNEUMOCOCCAL CARRIAGE AND COMMUNITY-ACQUIRED PNEUMONIA INCIDENCE IN KHABAROVSK CITY IN 2015

2016 ◽  
Vol 1 (62) ◽  
pp. 16-21 ◽  
Author(s):  
Татьяна Корита ◽  
Tatyana Korita ◽  
Людмила Бутакова ◽  
Lyudmila Butakova ◽  
Татьяна Каравянская ◽  
...  
Keyword(s):  
General Population ◽  
Respiratory Diseases ◽  
Age Groups ◽  
Incidence Rates ◽  
Community Acquired Pneumonia ◽  
Nasopharyngeal Carriage ◽  
Pneumococcal Infections ◽  
Epidemic Process ◽  
Pneumococcal Carriage ◽  
Annual Dynamic

The research objective was to study prevalence of pneumococcal nasopharyngeal carriage among different age-group populations as well as evaluate annual dynamics of nasopharyngeal carriage levels against incidence rates of community-acquired pneumonia in Khabarovsk city in 2015. The bacteriological research was conducted among 2429 people (1100 adults and 1329 children) suffering from respiratory diseases. The level of pneumococcal carriage of the whole group was equal to 12.3±0.67%. The pneumococcal carriage was registered in all age-groups; its highest levels were diagnosed in children from 1 to 3 years old and in children from 3 to 6 years old (27.0±2.16 and 23.1±1.97%, respectively). The incidence rates of community-acquired pneumonia equaled to 290.2 per 100000 of general population and 687.1 per 100000 of children population. The comparative analysis of annual dynamics of pneumococcal carriage and community-acquired pneumonia incidence rates among general population of Khabarovsk city and separately for children from 0 to 14 years old has shown a correlation between these epidemiologic manifestations. Typically, pneumococcal carriage and incidence rates are the lowest in August; they elevate in September due to influence of common factors that are associated with “mixing” of people. The peculiarity of annual dynamic of community-acquired pneumonia incidence rates is a double-wave course with maximum in April and September. The revealed trends show the correlation between epidemic process of community-acquired pneumonia and undetected epidemic process of pneumococcal infections manifested as pneumococcal carriage.

scholarly journals Age-related features of cancer incidence in Omsk and Orenburg Regions

2021 ◽  
Vol 6 (1) ◽  
pp. 41-46
Author(s):  
N. G. Shirlina ◽  
A. S. Kolchin ◽  
V. L. Stasenko ◽  
A. V. Klimushkin ◽  
S. V. Vyaltsin
Keyword(s):  
Cancer Incidence ◽  
Maximum Level ◽  
Fold Increase ◽  
Incidence Rates ◽  
Age Group ◽  
Upward Trend ◽  
Orenburg Region ◽  
Health Authorities ◽  
Age Related

Aim. To assess the age-related cancer incidence in Omsk and Orenburg Regions.Materials and Methods. We analysed the statistical reports (form 7) obtained from the health authorities of Omsk and Orenburg Regions from 2010 to 2019.Results. Age-specific indicators of cancer incidence in the indicated regions differed significantly (р < 0.001). In the Omsk Region, cancer incidence showed a 65-fold increase with age (from 20 to 79 years), reaching the maximum values at the age of 75-79 years and then decreasing in subjects > 80 years of age (p < 0.05). In the Orenburg region, age-related incidence rates increased 95-fold from 20 to 79 years, reaching a maximum level in the age group of 70-79 years, that was also followed by a decrease in the population over 80 years of age (p < 0.05). Trends in cancer incidence in Omsk and Orenburg Regions were similar to those in Russia, yet the rate was 1.4-1.8-fold lower. Cancer incidence in both regions had a moderate upward trend (increment of 1.2% and 1.5%, respectively; p < 0.001). The highest increase in cancer incidence was detected in subjects between 30 and 39 years and over 80 years of age (Omsk and Orenburg Regions, increment of 1.4% and 2.5%; 1.3% and 1.3%, respectively; p < 0.001).Conclusions. Cancer incidence in the Orenburg Region significantly exceeds that in the Omsk region, yet both of the regions are characterised by the specific trends. We found the most significant increase in cancer incidence in subjects > 80 years of age over the last decade, which was more pronounced in the Omsk Region in comparison with the Orenburg Region.

Effect of gender on age-specific effects for ulcerated malignant melanomas.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1603-1603
Author(s):  
Blakely S. Richardson ◽  
William F. Anderson ◽  
Jill Barnholtz-Sloan ◽  
Margaret A. Tucker ◽  
Meg R. Gerstenblith
Keyword(s):  
Large Scale ◽  
Tumor Biology ◽  
Age Groups ◽  
Older Men ◽  
Incidence Rates ◽  
Age At Diagnosis ◽  
Tumor Depth ◽  
Superficial Spreading ◽  
Men And Women ◽  
Malignant Melanomas

1603 Background: Gender, age at diagnosis, and ulceration are all independent prognostic factors for melanoma. The purpose of this study was to further examine the interactions among gender, age, and melanoma ulceration. Methods: Using the NCI’s SEER 17 Registries Database (2004-2008), we assessed ulceration status among White men and women with malignant melanoma, stratified by younger (ages 10-39 years) and older (ages 40-84 years) ages at diagnosis as well as by tumor depth. The analysis was restricted to melanomas common to both age groups, i.e. superficial spreading, nodular, and unclassified melanomas. There were 2905 older men, 301 younger men, 1624 older women and 276 younger women that fit our criteria. Relative risks were expressed as incidence rate ratios (IRR) with 95% confidence intervals (CI). Results: At every tumor depth, IRRs for ulcerated melanomas were significantly higher for older than younger persons (IRR>1.0). The trend, however, was different in men as compared to women. In men, the IRR (older to younger) rose continuously with increasing depth [≤1.0mm: IRR 7.81 (CI 6.18-9.98), 1.01mm-≤2.0mm: IRR 9.71 (CI 7.55-12.68), 2.01mm-≤4.0mm: IRR 11.04 (CI 8.78-14.06); and ≥4.01mm: IRR 12.26 (CI 9.60-15.87)]. On the other hand, in women, IRR (older to younger) was stable for all depths ≤4.0mm then nearly doubled for melanomas ≥4.01mm [≥4.01mm: IRR 8.00 (CI 5.85-11.20)]. The IRR trend analysis was statistically significant for men (p = 0.01) but not for women (p = 0.34). Conclusions: Our study confirms that older age at diagnosis is associated with higher incidence rates of ulcerated malignant melanomas. This large-scale population-based analysis also shows an effect modification by gender and tumor thickness, suggesting different biologic behavior in melanoma in younger and older men and women. Future studies should further investigate tumor biology differences in these populations and the interactions among gender, age at diagnosis, and ulceration in melanoma.

The structure of seroprevalence to the SARS-CoV-2 virus among residents of the Moscow Region during the period of epidemic incidence of COVID-19

2020 ◽  
Vol 18 (4) ◽  
pp. 17-26
Author(s):  
A.Yu. Popova ◽  
◽  
E.B. Ezhlova ◽  
A.A. Melnikova ◽  
O.M. Mikailova ◽  
...  
Keyword(s):  
Large Scale ◽  
Medical Center ◽  
Age Groups ◽  
Maximum Level ◽  
Test System ◽  
Moscow Region ◽  
Pcr Analysis ◽  
Enzyme Linked Immunosorbent Assay ◽  
Population Immunity ◽  
First Case

A pandemic of the disease caused by the SARS-CoV-2 virus (hereinafter referred to as COVID-19) was announced by WHO in February 2020. In the Moscow Region (MR), the first case of the disease was detected on March 7, 2020 in a woman who arrived from Switzerland. Four weeks later, a rapid rise began, the peak of which fell on the 20th week (May 11, 2020 – May 17, 2020), which was replaced by a gradual steady decline that lasted for 13 weeks. Objective. To determine the level and structure of population immunity to the SARS-CoV-2 virus among the population of the Moscow Region between June 22, 2020 and July 11, 2020. Patients and methods. A serological study of seroprevalence among residents of MR to COVID-19 was carried out from June 22, 2020 till July 11, 2020 during the period of a steady decline in the incidence. The work was conducted as part of the first stage of the large-scale Rospotrebnadzor program to assess population immunity to the COVID-19 virus among the population of the Russian Federation. Volunteers for the study were selected by the method of questioning and randomization. The analysis included the results of a survey of 2688 people. The number of volunteers in all age groups was equal. The content of specific IgG to the COVID-19 nucleocapsid was determined by the enzyme-linked immunosorbent assay using a test system manufactured by the FBIS SRCAMB according to the manufacturer's instructions. Results. The results of the study showed that the collective immunity of the total population of the Moscow Region was 21.0%. The maximum level of population immunity was established in children aged 14–17 years (30.7%) and 1–6 years old (25.2%). There were no statistically significant differences in the level of seroprevalence between men and women. As a result of seroepidemiological research, it was shown that in the medical center, in the presence of contacts with patients with COVID-19, the risk of infection increases by 2.5 times. After infection with COVID-19, antibodies were detected in 78.7% of cases. In persons with a positive result of the PCR analysis obtained earlier, antibodies were detected in 82.8% of cases. A high proportion of asymptomatic infection among seropositive volunteers was found, which amounted to 83.4%. Key words: coronaviruses, SARS-CoV-2, incidence, seroprevalence, the Moscow Region, population, COVID-19

scholarly journals Assessment of Population Immunity to SARS-CoV-2 Virus in the Rostov Region

2021 ◽  
pp. 117-124
Author(s):  
A. Yu. Popova ◽  
E. B. Ezhlova ◽  
A. A. Mel’nikova ◽  
A. K. Noskov ◽  
E. V. Kovalev ◽  
...  
Keyword(s):  
Herd Immunity ◽  
Age Groups ◽  
Incidence Rates ◽  
The State ◽  
Scientific Center ◽  
Education Professionals ◽  
Humoral Immune ◽  
Population Immunity ◽  
Rostov Region ◽  
High Level

By August 2020, more than 850000 cases of new coronavirus infection (COVID-19) caused by SARSCoV-2 were confirmed in the Russian Federation, with the Rostov Region as one of the ten most affected regions in Russia. The spread of the disease is largely determined by the state of population immunity in a certain area. Our research focuses on specific humoral immune response and estimates the level of herd immunity to SARS-CoV-2 virus among the population of the Rostov Region.Materials and methods. The study involved 3,048 people; the volunteers participating in the study were divided into seven age groups. The content of antibodies to SARS-CoV-2 was determined applying ELISA using a kit for the analysis of human serum or blood plasma for the presence of specific IgG to the nucleocapsid of the SARS-CoV-2 virus, manufactured by the State Scientific Center of Applied Microbiology and Biotechnology (Obolensk) in accordance with the instructions for use.Results and discussion. The assessment of seroprevalence to SARS-CoV-2 in the Rostov Region showed that the proportion of people positive for IgG to the new coronavirus was 16.5 %, the range of seropositive individuals in the general population was between 13.9 % and 19.1 % (p<0.05). There were no significant gender differences in the degree of seroprevalence with a positive result registered in 16.6 % of women and 16.5 % of men. A high level of humoral immunity to SARS-CoV-2 was established in individuals aged 1–17 against the background of low incidence rates, which may indicate the dominance of asymptomatic forms of the disease in this age group. The highest level of seropositivity was found in preschool children (33.6 %), students (29.3 %), employees (17.3 %), and education professionals (15.3 %). 

scholarly journals Strong Impact on the Polycyclic Aromatic Hydrocarbon (PAH)-Degrading Community of a PAH-Polluted Soil but Marginal Effect on PAH Degradation when Priming with Bioremediated Soil Dominated by Mycobacteria

2007 ◽  
Vol 73 (5) ◽  
pp. 1474-1480 ◽  
Author(s):  
Anders R. Johnsen ◽  
Stine Schmidt ◽  
Trine K. Hybholt ◽  
Sidsel Henriksen ◽  
Carsten S. Jacobsen ◽  
...  
Keyword(s):  
Contaminated Soils ◽  
Large Scale ◽  
Fold Increase ◽  
High Rate ◽  
Soil Bioremediation ◽  
Marginal Effect ◽  
Strong Impact ◽  
Pah Degradation ◽  
Degradation Rates ◽  
Polycyclic Aromatic

ABSTRACT Bioaugmentation of soil polluted with polycyclic aromatic hydrocarbons (PAHs) is often disappointing because of the low survival rate and low activity of the introduced degrader bacteria. We therefore investigated the possibility of priming PAH degradation in soil by adding 2% of bioremediated soil with a high capacity for PAH degradation. The culturable PAH-degrading community of the bioremediated primer soil was dominated by Mycobacterium spp. A microcosm containing pristine soil artificially polluted with PAHs and primed with bioremediated soil showed a fast, 100- to 1,000-fold increase in numbers of culturable phenanthrene-, pyrene-, and fluoranthene degraders and a 160-fold increase in copy numbers of the mycobacterial PAH dioxygenase gene pdo1. A nonpolluted microcosm primed with bioremediated soil showed a high rate of survival of the introduced degrader community during the 112 days of incubation. A nonprimed control microcosm containing pristine soil artificially polluted with PAHs showed only small increases in the numbers of culturable PAH degraders and no pdo1 genes. Initial PAH degradation rates were highest in the primed microcosm, but later, the degradation rates were comparable in primed and nonprimed soil. Thus, the proliferation and persistence of the introduced, soil-adapted degraders had only a marginal effect on PAH degradation. Given the small effect of priming with bioremediated soil and the likely presence of PAH degraders in almost all PAH-contaminated soils, it seems questionable to prime PAH-contaminated soil with bioremediated soil as a means of large-scale soil bioremediation.

scholarly journals Assessment of the Herd Immunity to SARS-CoV-2 among the Population of the Leningrad Region during the COVID-19 Epidemic

2020 ◽  
pp. 114-123
Author(s):  
A. Yu. Popova ◽  
E. B. Ezhlova ◽  
A. A. Mel’nikova ◽  
O. A. Historik ◽  
O. S. Mosevich ◽  
...  
Keyword(s):  
Herd Immunity ◽  
Significant Proportion ◽  
Maximum Level ◽  
Leningrad Region ◽  
Scientific Center ◽  
Epidemic Process ◽  
First Case ◽  
Applied Microbiology ◽  
Instructions For Use ◽  
The Unemployed

The first case of COVID-19 was registered in the Leningrad Region on March 13, 2020. The period of increasing intensity of the epidemic process lasted 8 weeks. One month after reaching the maximum incidence rate, a study was organized to determine seroprevalence to COVID-19 among the population of the Region.Objective of the study was to determine the level and structure of community immunity to SARS-CoV-2 virus in the population of the Leningrad Region in the period of intensive COVID-19 transmission.Materials and methods. The work was carried out within the framework of the Rospotrebnadzor project on assessment of community immunity to the SARS-CoV-2 virus in the population of the Russian Federation. The content of antibodies to SARS-CoV-2 was determined applying ELISA using a kit for the analysis of human serum or blood plasma for the presence of specific IgG to the nucleocapsid of the SARS-CoV-2 virus , manufactured by the State Scientific Center of Applied Microbiology and Biotechnology (Obolensk) in accordance with the instructions for use.Results and discussion. The study has showed that the herd immunity of the population of the Leningrad Region was 20.7 %. The maximum level has been established in children 1–6 years old (42.3 %) and people over 70 years old (29.0 %). The highest level of seropositivity, except for children and older people, was found among the unemployed (25.1 %). The lowest level of seroprevalence was detected in civil servants (12.8 %) and military personnel (16.7 %). It has been shown that the risk of infection increases by 1.5 times in case of contacts with COVID-19 patients. After exposure to COVID-19 virus, antibodies are produced in 82.1 % of the cases. In individuals with a positive PCR test result obtained earlier, antibodies are detected in 82.8 % of cases. The share of asymptomatic forms among seropositive residents of the Leningrad Region was 86.9 %. The results of assessing the herd immunity to SARS-CoV-2 in the population of the Leningrad Region indicate that during the period of intensive COVID-19 transmission, an average level of seroprevalence was formed. A significant proportion of asymptomatic forms of infection characterizes the high intensity of the latently developing epidemic process. The results obtained should be taken into account when organizing preventive measures, including vaccination, and predicting morbidity rates. 

The Incidence of Enterobiasis in Children Attending Educational Institutions of the Tyumen Region

2021 ◽  
pp. 63-69
Author(s):  
AN Letyushev ◽  
TF Stepanova ◽  
GV Sharukho
Keyword(s):  
Pearson Correlation ◽  
Univariate Analysis ◽  
Age Groups ◽  
Interval Data ◽  
Incidence Rates ◽  
Coefficient Of Determination ◽  
Comparative Characteristic ◽  
Educational Institutions ◽  
Epidemic Process ◽  
Testing Coverage

Introduction: Enterobiasis remains a predominant invasion in the structure of parasitic diseases. At the same time, judging by the incidence rates of enterobiasis, the activity of the epidemic process differs significantly from one region to another and even between cities of one and the same region. The purpose of our study was to assess the intensity of the epidemic process of enterobiasis based on incidence rates and pinworm testing coverage in children aged 3 to 6 years attending preschools and schoolchildren aged 7 to 14 years in the Tyumen Region. Materials and methods: We analyzed data on the incidence of enterobiasis (per 100 thousand population) and pinworm testing coverage (%) per 100 children of two age groups (3 to 6 and 7 to 14 years old) by municipalities of the Tyumen Region in 2013–2017. The interval data were analyzed using methods of variation statistics. To test the hypothesis that the differences between samples were random, a univariate analysis of variance was used. Additionally, the mean difference was calculated and its 95 % confidence interval was determined. The strength of the relationship between two variables was measured using the coefficient of determination, i.e. the square of the Pearson correlation coefficient. Results: We gave a comparative characteristic of the intensity of the epidemic process of enterobiasis based on the incidence and pinworm testing coverage data in 3 to 14-year-old children attending educational institutions of the Tyumen Region in 2013–2017 and assessed the deterministic relationship between the incidence rates of enterobiasis and the commitment of healthcare workers to pinworm detection testing in organized groups of children. Conclusions: We established that the incidence of pinworm infection in the child population of the Tyumen Region differed significantly between the administrative territories. It should be noted, however, that a relatively high incidence of enterobiasis in some areas was mainly attributed to a high pinworm testing coverage of children while in other areas a low coverage underestimated the incidence rate of enterobiasis and created a false impression of epidemiological welfare.

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