scholarly journals Condições clínicas de pacientes com hemofilia assistidos em um hemocentro regional: um estudo transversal

2020 ◽  
Vol 23 (269) ◽  
pp. 4731-4740
Author(s):  
Stefane Vieira Nobre ◽  
José Adelmo Da Silva Filho ◽  
Natália Bastos Ferreira Tavares ◽  
Thiáskara Ramile Caldas Leite ◽  
Raimundo Monteiro da Silva Neto ◽  
...  

The aim of the study was to characterize the sociodemographic and clinical profile of patients with hemophilia followed at a Regional Blood Center. Epidemiological cross-sectional study with data collection by document analysis with 30 records from a Regional Blood Center in the Center-South region of Ceará. Statistical analysis was performed using Microsoft Office Excel® 2016 software. The work was approved by the Research Ethics Committee. There was a predominance of males (27), aged 20 to 59 years, single marital status, incomplete elementary education, residing in rural areas and income below 01 minimum wage. As for the clinical profile, hemophilia A in severe form, has a sedentary lifestyle, with a history of transfusion procedures. Most have two or more associated clinical manifestations. With the prevalence pointed out among the participants, the need for comprehensive and equitable assistance is evident, with an emphasis on nursing actions.

2021 ◽  
Vol 9 (1) ◽  
pp. 57
Author(s):  
Ni Made Mertaniasih ◽  
I Gede Yogi Prema Ananda ◽  
Soedarsono Soedarsono ◽  
Deby Kusumaningrum

Tuberculosis diagnosis is an important component in decreasing TB incidence and prevalence. Because of the difficulty to collect sputum in some cases, urine specimens are used as it is easier to garner. One of the biomarkers in urine that can be used to diagnose pulmonary TB is IP-10, which can be represented by the CXCL10 gene. The study aims to determine the accuracy of diagnosis based on detection of the CXCL10 gene in urine as a biomarker for the patients with suspected pulmonary TB in Dr. Soetomo Hospital in Surabaya from November 2019 until March 2020. Thus, this is an observative laboratory research with a cross-sectional study. CXCL10 gene was examined using PCR for 36 urine samples, and then, the data, together with the medical records of clinical manifestations of pulmonary TB, GeneXpert MTB /RIF, blood count, and thorax radiograph, were processed using IBM SPSS Statistics 26. The results of the GeneXpert MTB/RIF and thorax radiograph criteria show positive results of pulmonary TB, which were 44.4% and 69.4% respectively. CXCL10 gene was not found in all urine of healthy people (negative), while 2.8% (1/36 samples) positive CXCL10 gene was found in a patient with positive GeneXpert, also with negative clinical manifestations and urine culture. In this study, the accuracy of diagnosis based on detection of the CXCL10 gene in urine for diagnosis of active pulmonary TB was 2.8%. Future research is needed to improve the methods, among them are bigger size of urine samples and clearer medical history of patients. 


Author(s):  
Viral R. Dave ◽  
Bhavik M. Rana ◽  
Kantibhai N. Sonaliya ◽  
Suraj J. Chandwani ◽  
Samkit V. Sharma ◽  
...  

Background: Hypertension and gestational diabetes are among the leading causes of maternal and perinatal mortality, especially in rural areas of developing countries with meager health facilities. With early diagnosis and timely treatment, these adverse events can be decreased. The primary aim of this study was to implement a screening program for gestational diabetes and hypertension, and to assess risk factors associated with these conditions among antenatal women in the rural area of the Gujarat province in India.Methods: A cross–sectional study was conducted at one of the rural areas of Gujarat province in India. Following a random  cluster sampling procedure, the village of Davas was selected. A multistage random sampling method was utilized, resulting in a sample of 346 antenatal women. Screening guidelines from the American Diabetes Association were followed for gestational diabetes screening.Results: The majority of antenatal mothers (55.50%) were between 21-25 years of age. 242 antenatal women were multigravida, and among them, 85.96% had institutional delivery at their last pregnancy. Of the total 346 women, 17.60% were prehypertensive. The prevalence of systolic hypertension was 1.40%, diastolic hypertension was 0.90%, and gestational diabetes was 1.73%.Conclusion: Socioeconomically upper class, a family history of hypertension, and BMI ≥ 25 were strong risk factors for hypertension during pregnancy and gestational diabetes. Health education should be made readily available to antenatal mothers by paramedical workers regarding symptoms of hypertension and gestational diabetes mellitus for early self identification.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
S. M. Seck ◽  
D. G. Dia ◽  
D. Doupa ◽  
A. Diop-Dia ◽  
I. Thiam ◽  
...  

Diabetes represents a challenging global health issue in the 21st century. Data from sub-Saharan African populations are scarce and are usually restricted to urban settings. The objective of this study was to compare prevalence and risk factors of diabetes in rural and urban areas in Senegal.Methods.In a community-based survey between January and May 2012, we included 1027 adults aged≥18 years living in northern Senegal. Sociodemographic, clinical, and biological data were collected during household visits. Multivariate logistic regression was performed to identify factors associated with diabetes.Results.Mean age of participants was48.0±16.9years and 65.7% were female. Participants from urban area represented 55.7%. The age-standardized prevalence of diabetes was 7.6% (6.0% in men versus 9.0% in women). Prevalence of diabetes was higher in urban areas (8.1%) compared to rural areas (4.6%). Disease awareness rate was 43%. After multivariate analysis, age (OR = 1.63,p=0.001), familial history of diabetes (OR = 1.42,p=0.001), and abdominal obesity (OR = 1.17,p=0.05) were associated with diabetes.Conclusion.Diabetes is frequent in urban and rural areas in Senegal. Awareness rate is very low among populations. Age, family history of diabetes, and abdominal obesity are the main risk factors identified.


2021 ◽  
Author(s):  
Amira Siddig ◽  
Khabab Abbasher Hussien Mohamed Ahmed ◽  
Ahmed Abdelrahman ◽  
AlHussien Abbasher ◽  
Abubaker Alsedig Abbasher ◽  
...  

Abstract Background: Patients with dementia are more prone to acquire COVID-19 infection. Patients with COVID-19 showed a tendency to develop cognitive impairment. Objectives: We aimed to study the clinical manifestations of COVID-19 infection among adult Sudanese demented patients and the prevalence of cognitive impairment among adult Sudanese non demented patients. Methodology: This is a descriptive cross-sectional study which took place in Sudan, Khartoum state in the period (September-December 2021) in a private neurology/psychiatry clinic. 135 adult Sudanese patients were included in this study and were divided into two groups. The first group consists of 100 patients with a known history of dementia that got infected recently with COVID-19, while the second group consists of 35 patients who developed some sort of cognitive impairment after recovering from COVID-19 infection. Regarding the second group, cognitive functions were assessed by senior consultant neurologist and senior consultant psychiatrist using a well validated neuropsychological measure. Results: Out of 100 patients in the first group, females were 60 and males were 40. Age distribution is between 63 -98. The common presenting symptoms of COVID-19 among this group were: Cough and fever (90 patients), diarrhea and vomiting (5 patients), breathlessness (4 patients), coughing of blood (5 patients), convulsions (1 patient), paraplegia (1 patient) and hemiplegia (1 patient). Regarding the second group, Age distribution varied from 30 to 80 years. Cognitive functions impairment was noticed as follows: Memory recall (22%), memory recognition (23%), memory encoding (24%), processing speed (16%), executive functioning (19%), phonemic fluency (17%) and category fluency (17%). Conclusion: Patients with dementia are more susceptible to develop COVID-19 infection. Patients with COVID-19 Infection are at risk of developing some sort of cognitive impairment after recovery.


2010 ◽  
Vol 36 (1) ◽  
pp. 1-3 ◽  
Author(s):  
A.F.M. Sarwar ◽  
SK. Akhtar Ahmad ◽  
Manzurul Haque Khan ◽  
M.H. Selim Ullah Sayed ◽  
Md. Humayun Kabir

This cross-sectional study was carried out in some selected arsenic contaminated rural areas of Bangladesh to determine any clinical changes in oral cavity, among the arsenic exposed population through drinking water. Total 600 respondents (200 arsenicosis patients, 200 non-patients but having the history of taking arsenic contaminated water and another 200 arsenic non-exposed). 75.5% of arsenicosis patients had swelled vallate papillae whereas only 44.5% and 8.5% in case of arsenic exposure and non-exposure subjects respectively. The differences were found statistically significant (p<0.001). This study suggests that there is a tendency of developing swelled vallate papillae among the arsenic exposed population. Online: 10 July 2010DOI: http://dx.doi.org/10.3329/bmrcb.v36i1.4479Bangladesh Med Res Counc Bull 2010; 36: 1-3


Author(s):  
Sunil Kumar Ahuja ◽  
Nimisha Mishra ◽  
Pradeep Kumar

Background: Better knowledge of socio-demographic profile and obstetric features may help in early identification and treatment of patients with post-partum psychosis. The aim of present research is to study the age, parity, socio-demographic and obstetric and menstrual profile of patients suffering from post-partum psychosis. Setting and Design: A cross-sectional study at in-patient department of psychiatry, SS Medical College and associated SGMH Rewa.Methods: The study was conducted on sixty patients of post-partum psychosis admitted in psychiatry ward. Detailed socio-demographic characteristics, obstetric and menstrual profile along with psychiatric assessment were recorded in proforma specially designed for the study.Results: Bulk of our post partum psychotic subjects (60%) were in the age range of 18-25 years with 83.33% of women were residing at rural areas. Most of subjects (76.67%) of post partum psychosis were illiterate. 73.33% patient were belonging to low socio-economic status and remaining to middle and high socioeconomic status. Majority of subjects (13.33%) were house wife (86.67%) followed by laborer class. Family jointness reveal 80% and 20% of subjects trailed from joint and nuclear family respectively. the maximum number of subjects (60%) were primipara with only 13.33% of subjects had history of obstetric complication in form of prolonged labour and post-partum heamorrhage. 25% subjects had cesarean delivery. 40% patients of puerperal psychosis were having menstrual irregularity and 60% had regular menstruation.Conclusions: Screening of vulnerable groups i.e. younger age, primipara, history of irregular menstruation in post partum period for psychiatric sign and symptoms is requisite for early diagnosis and prompt and adequate management. As most of the patients were from rural areas it is necessary to establish psychiatric services in rural areas as well so that this group of population can be provided holistic care along with already existing medical services.


2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Hairui Zhang ◽  
Ran Ren ◽  
Jinlin Liu ◽  
Ying Mao ◽  
Guowei Pan ◽  
...  

Background. Patients with chronic liver disease (CLD) have extrahepatic manifestations and impaired health-related quality of life (HRQOL), and hepatitis C virus (HCV) infection is a leading cause of CLD, cirrhosis, and hepatocellular carcinoma (HCC). This study is aimed at assessing HRQOL in patients with HCV infection in the rural areas and identifying factors associated with impairment of HRQOL. Methods. A cross-sectional study was conducted in a county of Liaoning Province in northeast China. HRQOL of patients with HCV infection was assessed using the chronic liver disease questionnaire (CLDQ) and EuroQol-5 dimensions (EQ-5D). Data were transformed to score comparisons of six major CLDQ domains, EQ index, and visual analog scale (VAS). Results. A total of 397 (93.4%) subjects, including 67 healthy subjects (HSs), 314 patients with chronic hepatitis C (CHC), and 16 patients with liver cirrhosis (LC) completed the study. The overall quartile CLDQ scores for HSs, patients with CHC, and patients with LC were 6.4 (6.0, 6.7), 5.8 (4.6, 6.4), and 4.1 (3.0, 6.0), respectively. The quartile scores of EQ index for the three groups were 1.0 (1.0, 1.0), 1.0 (0.8, 1.0), and 0.9 (0.6, 1.0), respectively. The median scores of EQ VAS for the three groups were 85.0, 60.0, and 60.0, respectively. Female sex, patients with family history of hepatitis, other comorbid chronic diseases, drinking, and disease duration≥10 years were associated with significant improvement in overall CLDQ scores, and family history of hepatitis and other comorbid chronic diseases were considered predictive factors for EQ index and VAS, respectively. Conclusions. Compared with HSs, HCV infection had a greater negative impact on HRQOL in patients with CHC and LC. The significant factors associated with HRQOL include female sex, patients with a family history of hepatitis, other comorbid chronic diseases, drinking, and disease duration≥10 years. Patients with HCV infection in the rural areas should be paid careful attention regarding their HRQOL with proper health education and disease management.


1969 ◽  
Vol 3 (1) ◽  
pp. 258-262
Author(s):  
IQBAL WAHID ◽  
HAMID HUSSAIN ◽  
SADULLAH AFRIDI ◽  
ZIA UR REHMAN ◽  
SALEHAAFRIDI ◽  
...  

Objectives: Hypertension is a chronic medical condition. Some observers say that 20% of population aged18 74 years suffered from hypertension and l /3rd of them are not aware that they are hypertensive. More than70% of all hypertensive patients (85% in rural areas) in Pakistan are not aware of their disease.Methods: A cross-sectional study design was used to estimate the prevalence, awareness and factorsassociated with hypertension. Sample of 500 teachers was selected. Data were analyzed using statisticalpackage for social sciences version 16.0.Results: The prevalence of hypertension was found in 128/500 (25.6%) teachers. Out of these 128, 50(40%)were not aware of their hypertensive status. Old age, family history of hypertension, obesity, lack ofexercise, smoking and living stressful life are pre-determinants of hypertension in the teachers.Conclusion: The teachers should get their blood pressures checked on a regular basis, so that any increase inblood pressure can be properly monitored. The teachers should be encouraged to take walks or do lightexercise regularly during their free time. This will help them deal with their sedentary lifestyle and obesity.Lowering weights will concurrently deal with hypertension.Key words: Hypertension, Prevalence,Awareness,Teachers, University, Peshawar


Author(s):  
Vahid Mashayekhi Mazar ◽  
Ali Dehghani ◽  
Masaood Mirzaee ◽  
Mohsen Askarshahi ◽  
Mohammad Reza Sharifi ◽  
...  

Introduction: Due to the global burden of measles, many measures have always been taken to control and eradicate this disease. However, epidemics of this disease still sometimes occur in some parts of the world and Iran. The aim of this study was to investigate the epidemiology of measles cases in the south of Kerman Province during 2014-2015. Methods: This descriptive cross-sectional study was performed on 326-suspected cases of measles using a checklist and review forms. Data were analyzed by SPSS software version 16. Results: During the years of 2004 and 2005, out of the total number of suspected cases (n=326), 23% were laboratory confirmed. The highest percentage of measles was in the age group of 1 to 4 years (45.3%) and above 10 years (30.7%) and the highest cases of measles were among males (61.3%). Most cases of definite measles were in people without a history of vaccination (61.3%), in Iranians (81.3%) and in rural areas (73.3%). Conclusion: According to the results of the study, there is a need to pay attention to additional immunization in remote areas and in places of gathering of foreign nationals. The highest prevalence of measles were among people who did not have a history of measles vaccination, it seems that the measles vaccination program has not been very successful in the cities covered by the Jiroft University of Medical Sciences. It is recommended that additional studies be performed to determine the risk factors for measles.


2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Marhamah Hasnul ◽  
Najirman Najirman ◽  
Yanwirasti Yanwirasti

Abstrak Penyakit jantung rematik (PJR) adalah penyakit jantung sebagai akibat adanya gejala sisa (sekuele) dari demam rematik (DR) yang ditandai dengan terjadinya cacat katup jantung. Tujuan penelitian ini adalah melihat karakteristik pasien penyakit jantung rematik.yang dirawat. Metode yang digunakan adalah deskriptif observasional dengan desain cross sectional study dan pendekatan retrospektif untuk menilai karakteristik pasien PJR di RSUP Dr. M. Djamil Padang dari Januari 2009 - Desember 2012. Populasi dan sampel sebanyak 54 sampel. Hasil penelitian menunjukkan distribusi pasien terbanyak pada kelompok umur 11-20 tahun (50%), perempuan (57,41%), tingkat pendidikan SD/sederajat dan SLTP/sederajat masing-masing 25,93%, pelajar/mahasiswa (53,70%), dan berasal dari daerah rural (70,37%). Sebagian besar pasien mengeluhkan keluhan utama sesak napas (62,96%). Hasil pemeriksaan elektrokardiografi memperlihatkan LVH sebesar 35,19% dan AF sebesar 27,78%. Berdasarkan pemeriksaan foto toraks umumnya pasien telah mengalami kardiomegali (92,59%). Berdasarkan pemeriksaan ekokardiografi yang paling banyak ditemukan adalah kelainan katup regurgitasi mitral (30,40%), derajat kerusakankatup berat (36,80%), dan fraksi ejeksi normal (72,97%). Pada penelitian ini dapat disimpulkan bahwa terdapat variasi karakteristik dari penderita PJR yang ada di RSUP Dr. M. Djamil Padang. Kata kunci: penyakit jantung rematik, karakteristikAbstract Rheumatic heart disease is a cardiovascular disease caused by delayed sequele of rheumatic fever characterized by heart valve damage. The objective of this study was to observe the characteristics of RHD patients.This study is a descriptive observasional with cross-sectional study design and the retrospective by observing the characteristics of RHD patients in RSUP Dr. M. Djamil Padang from Januari 2009 – December 2012. The population and sample of this study was 54 patients. The result of this study showed that majority of the patients at the age group 11-20 years (50%), female (57.41%), elementary education degree/equal and junior high/equal of each 25.93%, students/university students (53.70%), and come from rural areas (70.37%). Most patients complained experiencedbreathlessness (62.96%). The result of electrocardiography showed LVH is the the highest (35.19%) and AF 27.78%. Based on chest X-ray examination majority of the patients showed a cardiomegaly (92.59%). Based on echocardiography examination, the most heart valve damage is mitral regurgitation (30.40%), the severity is severe (36.80%), and the fraction ejection is in normal limit (72.97%). The conclusion of this research, there are variation in the characteristics of RHD patients in RSUP Dr. M. Djamil Padang.Keywords: rheumatic heart disease, characteristics


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